Leopardus geoffroyi (Geoffroy's cat): 123604364
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Entry
123604364 CDS
T10761
Symbol
PFAS
Name
(RefSeq) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
lgf Leopardus geoffroyi (Geoffroy's cat)
Pathway
lgf00230
Purine metabolism
lgf01100
Metabolic pathways
Module
lgf_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
lgf00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
123604364 (PFAS)
Enzymes [BR:
lgf01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
123604364 (PFAS)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
AIRS
Motif
Other DBs
NCBI-GeneID:
123604364
NCBI-ProteinID:
XP_045346292
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All DBs
Position
E1:2866159..2884843
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AA seq
1336 aa
AA seq
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MPSVLHFYVRPSGHERAASGHTRRKLQGKLPELQAVETELCYNVNWTADSLPSAEEMKKL
TWLFGCPLLLGDVAQESWLRSDSSDLLLEVGPRLNFSTPASTNIVSVCWAAGLGAVDRVE
TTRRYLLSFAKPPSSETKTLALATLHDRMTEQHFPRPIQSFSLRSMSAPLNGQIDILAEG
RRALEKANQELGLALDSWDLDFYTKRFQELKRNPSTVEAFDLAQSNSEHSRHWFFKGQLH
MDGQEMTHSLFEAIMSTQASSNPNNVLKFCDNSSAIQGKEVRFLQPEDPTRPSCFRQQRA
LRHVVFTAETHNFPTGVAPFSGATTGTGGRIRDVQCTGRGAHVVAGTAGYCFGNLHIPGY
NLPWEDPSFQYPENFARPLEIAIEASNGASDYGNKFGEPVLAGFARSLGLQLPDGQRREW
IKPIMFSGGIGSMEAEHVSKEPPEPGMDVVKVGGPVYRIGVGGGAASSVQVQGDNSSDLD
FGAVQRGDPEMEQKMNRVIRACVEAARGNPICSLHDQGAGGNGNVLKELSDPAGAVIYTS
RFQLGDPTLNALEIWGAEYQESNALLLRPVDRDFLSHVSARERCPACFVGTITGDRRIVL
VDDRDCPVGRNGEGDAPSPPTPVDLELDWVLGKMPRKEFFLQRSLPMLRPLALPPGLSVR
QALERVLRLPAVASKRYLTNKVDRSVGGLVAQQQCVGPLQTPLADVAVVALSHQELVGAA
TALGEQPVKSLLDPKVAARLAVAEALTNLVFALVTDLRDVKCSGNWMWAAKLPGEGAALA
DACAAMVAVMAALGVAVDGGKDSLSMAARVGSETVRAPGSLVISAYAVCPDITATVTPDL
KRPGGRGRLLFVPLSPGQHRLGGTALAQCFSQLGEQPPNLDLPENLVRAFRITQGLLRDR
LLCSGHDVSDGGLVTCLLEMAFAGNCGIEVDVPAPGVDALPALFAEEPGLVLEVRGPDLA
QVLKRYRDAGLYCLELGATGDAGPHALVRVSVNGAVVLEESVRQLRALWEETSFQLDRLQ
AEPRCVAEEEQGLRERTGPTYRLPPGFPKASVPREPGGPIPRVAILREEGSNGDREMADG
FHLAGFEVWDVTMQDLCSGAIGLDTFRGVAFVGGFSYADVLGSAKGWAAAVTFHPLAGAE
LRRFRKRPDTFSLGVCNGCQLLALLGWVGGSPSEEAEGTGQDSWPAQPGLLLRHNLSGRF
ESRWASVRVGPGPALMLRGMEGAVLPVWSAHGEGYMAFSSPELQAQIEARGLAPLHWADD
DGNPTEQYPLNPNGSPGGVAGVCSLDGRHLALMPHPERAVRLWQWAWQPPPFDTLSTSPW
LQLFINARNWTREGGC
NT seq
4011 nt
NT seq
+upstream
nt +downstream
nt
atgccctcagtccttcacttctatgtccgtccctctggccatgagagggcggcctctgga
cacactcggaggaagctgcaagggaaattgccagagctgcaggctgtcgagaccgagctg
tgctacaacgtgaactggacagcggactccctcccaagcgccgaggagatgaagaagctc
acgtggctctttggctgccccttgttactgggtgatgttgcccaggagtcctggctccgt
tctgactccagcgacctactgctggaggtcgggcccaggctgaacttctccaccccagcc
tctaccaatatcgtgtccgtctgctgggctgcggggctgggggccgtggatcgcgtggag
actacccggcgctacctgctctcgtttgccaagcccccttcctctgagacgaagaccttg
gctctggctaccctgcatgaccggatgacagagcagcacttcccgcggcccatccagagc
ttctcccttcggagtatgtcagcgcctctcaacggccagatcgacatcctggcagagggc
cggcgtgccctggaaaaagccaaccaggaactaggcctggccctagactcctgggacctg
gatttctacaccaaacgcttccaggagctaaagcggaaccccagcaccgtggaggccttc
gacctggctcagtccaatagcgagcacagccgacactggttcttcaagggccagctccac
atggatgggcaggagatgacgcactccctgtttgaggccatcatgagcactcaggcgtcc
tcgaaccccaacaacgtcctcaagttctgtgacaacagcagtgcaatccaagggaaggaa
gtccgattcctacagcccgaggaccccacgcgaccaagctgcttccggcagcagcgggcg
ctgagacatgtcgtcttcacggcggagacccacaacttccccacaggagtagcccccttc
agtggggcgaccacaggcaccgggggccggatccgagatgtccagtgcacgggccgtggc
gcccacgtggtggctgggactgctggctactgctttggaaacctgcacatcccaggttac
aatttgccctgggaggacccaagcttccagtatcctgagaactttgcccgacccctggag
atcgccattgaggccagtaatggggcttctgattacggcaacaagttcggggagccagtg
ctggccggcttcgcccgctccttgggcctccagctcccggacggccagcggcgtgagtgg
atcaaacccatcatgtttagtgggggcattgggtccatggaggctgagcatgtgagcaag
gagcccccagagccaggcatggacgttgtaaaggttgggggtcccgtctacaggatcgga
gtcgggggtggagccgcctcgtctgtgcaggtgcagggagacaattccagtgacctggac
tttggggctgtgcagcggggagacccggagatggaacagaagatgaaccgtgtgatccgg
gcttgcgtggaggccgccagggggaaccccatctgcagcctccacgaccagggtgccggt
ggcaatggcaacgtcctgaaggaactgagtgacccggctggagctgtcatttacaccagc
cgcttccagctcggggacccgaccctgaatgccctggaaatctggggggccgagtaccag
gagtcgaatgctcttctgctgaggcccgtggaccgagacttcctcagtcatgtcagcgcc
cgggagcgctgcccagcttgctttgtgggcaccattacgggagacaggaggatcgtgctg
gtggacgatcgcgactgtcccgtcggaagaaatggcgaaggggacgccccctcgcccccg
acccctgtggacctggagctggattgggtgctgggcaagatgcctcggaaggagttcttc
ctgcagcggagtctccccatgctgcggcctctggccttgcccccggggctgagtgtgcgc
caggctctggagcgcgtcctgaggctgcctgctgtggccagcaagcgatacctcaccaac
aaggtggaccgctccgtgggcggcctggtggcgcagcagcagtgcgttgggcccctgcag
acccctctggccgacgtggcggttgtggcattgagtcaccaggagctcgtaggggctgcc
accgctctaggagagcagccggtcaaaagcctgctggaccccaaggttgccgcccgactg
gctgtggccgaagccctcaccaacctggtgtttgctctggtcaccgacctccgggacgtg
aagtgcagcgggaactggatgtgggcggccaagctcccgggggagggcgcggctctggcc
gacgcctgcgcggcgatggtggcggtgatggcggccttgggtgtggcggtggacggtggc
aaggactccctcagcatggccgcccgggtcggctctgagaccgtgcgggcccccgggtcg
ctggtcatctcggcctatgctgtctgtccggacatcacagccaccgtgaccccggacctc
aagcgtcctgggggcagaggccggctgctgttcgtgcctctgagccccgggcagcaccgg
ctggggggcacagccctggcccagtgcttctcgcagctgggcgagcagcccccgaacctg
gaccttcccgagaacctggtgcgtgccttccgcatcacacaggggctgctgcgagaccgt
ctcctctgctcaggccacgatgtcagtgacgggggcctcgtcacctgcctgctagagatg
gcctttgctgggaattgtgggatagaggtggacgtgcctgcccctggggtcgatgcgctg
cctgcattgttcgctgaggagccgggcctggtgctggaggtgcgggggcccgacctggcc
caggtgctgaagcgctaccgggacgccggcctgtactgcctggagctgggcgccacgggc
gacgccgggccccacgccctggtgcgagtgtccgtgaacggggctgtggttctggaagag
tctgtgaggcagctgcgagccctctgggaggagacgagtttccagctggaccggctgcag
gccgagccgcgctgtgtggcggaggaagagcaggggctcagggagcggacggggcccact
taccgcctgcccccaggcttccccaaagcttccgtgccccgagagcctggcggtcccatt
ccccgagttgccatcttgcgagaggagggcagtaacggagaccgcgagatggcggacggc
ttccacttggccgggttcgaggtgtgggatgtgaccatgcaggacctctgctctggggcg
atcggtctggacacgttccgcggcgtggccttcgtgggcggcttcagctatgcggatgtc
ctgggctctgccaaagggtgggccgctgctgtgaccttccacccgctagctggggctgaa
ctgagacgtttccgaaagcggcccgacaccttcagcctgggcgtgtgtaatggctgtcag
ttgctggctctgctgggctgggtaggaggtagccccagcgaggaggcagaggggacaggc
caggactcctggccggcccagccgggcctcctgcttcgccacaacctgtctgggcgcttt
gagtcccgctgggccagtgtgcgggtgggtcctgggccggccctgatgcttcgagggatg
gaaggagctgtgctacccgtgtggagcgctcatggcgaaggttacatggctttttcttct
ccggaactccaagcccagattgaggccaggggcttggctccgctgcactgggccgacgac
gacgggaaccctacagaacagtatcccctgaaccccaatgggtccccagggggcgtggct
ggtgtctgctccctcgatggccgccacctggccctcatgcctcaccctgagcgggctgtg
cggctttggcagtgggcgtggcagcctcctccctttgacactctgagtacctccccctgg
ctccagctcttcatcaacgcccgaaactggacccgggaggggggctgctga
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