Leopardus geoffroyi (Geoffroy's cat): 123605271
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Entry
123605271 CDS
T10761
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
lgf Leopardus geoffroyi (Geoffroy's cat)
Pathway
lgf04217
Necroptosis
lgf04380
Osteoclast differentiation
lgf04620
Toll-like receptor signaling pathway
lgf04621
NOD-like receptor signaling pathway
lgf04630
JAK-STAT signaling pathway
lgf04658
Th1 and Th2 cell differentiation
lgf04659
Th17 cell differentiation
lgf05145
Toxoplasmosis
lgf05160
Hepatitis C
lgf05161
Hepatitis B
lgf05162
Measles
lgf05164
Influenza A
lgf05165
Human papillomavirus infection
lgf05167
Kaposi sarcoma-associated herpesvirus infection
lgf05168
Herpes simplex virus 1 infection
lgf05169
Epstein-Barr virus infection
lgf05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
lgf00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
123605271 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
123605271 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
123605271 (TYK2)
04621 NOD-like receptor signaling pathway
123605271 (TYK2)
04658 Th1 and Th2 cell differentiation
123605271 (TYK2)
04659 Th17 cell differentiation
123605271 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
123605271 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
123605271 (TYK2)
05160 Hepatitis C
123605271 (TYK2)
05171 Coronavirus disease - COVID-19
123605271 (TYK2)
05164 Influenza A
123605271 (TYK2)
05162 Measles
123605271 (TYK2)
05168 Herpes simplex virus 1 infection
123605271 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
123605271 (TYK2)
05169 Epstein-Barr virus infection
123605271 (TYK2)
05165 Human papillomavirus infection
123605271 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
123605271 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
lgf01001
]
123605271 (TYK2)
Enzymes [BR:
lgf01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
123605271 (TYK2)
Protein kinases [BR:
lgf01001
]
Non-receptor tyrosine kinases
JAK family [OT]
123605271 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kdo
Kinase-like
FERM_C_FAK1
ABC1
RIO1
RA_2
Motif
Other DBs
NCBI-GeneID:
123605271
NCBI-ProteinID:
XP_045347820
LinkDB
All DBs
Position
A2:complement(7838373..7858961)
Genome browser
AA seq
1181 aa
AA seq
DB search
MPLCRWGATTRDSRPDGDEAQSMVSRGGLKVLLHWAGPDGGDPWVTFSEATLTAEEVCIH
IAHKVGITPSCLNLFALFDAQAQVWLPPNHILEVSRDMNLTLYFRMRFYFRNWHSMNPQE
PAVYRCGPTRAKSSSEQAEQGMQLLDPASFEYLFEQGKHEFVNDVAPLWELSSEEEIHHF
KNESLGMAFLHLCHLALCHGIPLEKVAKKISFKDCIPRSFRLQLRRHNALTRLRLRRLFR
RFVRAFQPGHVSQPVIMVKYLATLEQLAPRFGTERVLVCRLEEQAQAVGDPCYVQDGGQS
PPEPGPELAPGPPTHEVLVTGTGGIRWRPVQAEGPSGDGCSRNPRAGPSGKKSKAQEVGS
QPADRPQEAPWAYFCDFQDITHVVLKERHVSIHCQDKCLELTLPSRAVALSLVSLVDGYF
RLTADSSHYLCREVAPPRLVMSIRDGIHGPLLEPFVLAKLRPEDGLYLIHWSTSHLNRLI
LTVAQRDQAPGGQQLHLRKFPIELRAGSFELEGWDRSFPSVRELRTALQGCSLRAGDDCF
SLRRCCLPRPGELSNLIIMRGSRASPGPLNLSQLSFHRVCQDDITQLSHLGQGTRTNVYE
GILRVGERGPKEGTTDGGDPSTPSGDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVS
HVHLAFVHGVCVHGSENIMVTEYVEHGPLDVWLRRERGHVPVAWKVAVAQQLASALSYLE
DKSLVHGNVCGRNILLARLGLAEGSSPFIKLSDPGVGLGALSREERVERIPWTAPECLSG
GASTLTTAADKWGFGVTLLEICFDGEAPLQGRGPSEKECFYQKQHQLPQPSCPELATLTS
QCLTYEPAQRPSFRTILRDLTQLQPQNLADVLAVNPDSPASDPTVFHKRYLKKIRDLGEG
HFGKVSLYCYDPTNDGTGEMVAVKALKAGGGPQLRTGWRREIDILRTLYHKHIVKYKGCC
EDQGEKSVQLVMEYVPLGSLRDYLPRHNVGLAQLLLFAQQICEGMAYLHAQHYVHRDLAA
RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKECKFYYASDVWS
FGVTMYELLTYCDSSQSPPSKFIELIGLTQGQMTVLRLTELLERGERLPRPEKCPCEIYL
LMKNCWEAEASFRPTFQNLIPILKTVQEKYQGQAASVFNVC
NT seq
3546 nt
NT seq
+upstream
nt +downstream
nt
atgcctctgtgccgttggggtgccaccaccagggacagcaggcctgatggggatgaggct
cagtccatggtctccaggggaggcctaaaggtccttctgcactgggctggccctgatggc
ggggacccctgggtcaccttcagcgaggccacactgaccgcagaggaggtctgcatccac
atcgcacacaaagtcggcatcactccatcctgcctcaatctcttcgccctctttgatgcc
caggcccaggtgtggctgcccccaaaccacatcttggaggtctccagagacatgaacctg
acattgtacttccgcatgaggttttatttccggaactggcacagcatgaatcctcaggag
ccggctgtgtaccgctgtgggcccaccagggccaagtcttcctcggagcaggcagagcag
gggatgcaactcctggacccagcctcctttgagtacctctttgagcagggcaagcacgag
tttgtgaatgatgtggcaccactgtgggagctgtcgagcgaggaggagatccaccatttt
aagaacgagagcctgggcatggcctttctgcacctctgccaccttgccctttgccacggt
atccccctggagaaggtggccaagaagatcagcttcaaggactgcatcccgcgctccttc
cggctgcagctccggcggcacaacgcgttaacacggctgcgcctacggagactcttccgc
aggtttgtgcgggccttccagccgggccacgtctcccagccggtcatcatggtcaagtac
ctggccacgctggagcagctggcaccccgcttcggcacggagcgcgtgctcgtgtgccgg
ctggaggagcaggcccaggccgtgggggacccctgctacgtccaggacgggggccagtcc
cccccggagcctgggcctgaattggcccccggaccccctactcatgaggtgctggtgaca
ggcactggtggcatccggtggcggccagtccaggcagagggtcccagtggcgatggttgc
agcaggaacccccgtgctggcccatcggggaagaaaagcaaggcccaggaggtgggcagc
cagccagcggacagacctcaggaagcgccatgggcctacttctgtgacttccaggacatc
acccacgtggtgctgaaagagcgccatgtcagcatccactgtcaggacaagtgcctggag
ctcaccctgccttcccgggctgtggccctgtccttggtgtcgctggtggacggctatttc
cgcctgacagccgactcgagccattacctgtgccgggaggtggcccctccgcggctggtg
atgagcatccgggatggcatccacgggcccttgctggagccgttcgtgctggccaagctg
cggcccgaagatggcctctacctcatccactggagcaccagccacctcaaccgtctcatc
ctcacggtggcccagcgtgaccaggcacctggcgggcagcagctgcacctccgtaaattc
cccattgagctgcgggccgggagcttcgagctggagggctgggaccgctccttcccgagc
gtgcgggagctgcgcaccgccctgcagggctgctcgctgcgggccggggacgactgtttc
tccctgcgccgctgctgcctgccacggcccggagagctctccaacctcatcatcatgcgt
gggtctcgggccagccctgggccactcaacctcagccagctcagcttccaccgcgtctgc
caggatgacattacccagctgtctcacttaggccaaggcacgaggaccaatgtgtatgag
ggcatcttacgggtgggggaaagaggccccaaggagggcacgacagatggtggggacccc
tccacgcccagtggggaccgtgggcaggagctacgagtggtactcaaggtgctggatccc
agtcaccacgacatcgccctggccttctacgagacagccagcctcatgagccaggtctcc
cacgtgcacctggcctttgtgcacggcgtctgcgtgcacggctctgagaacatcatggtg
acagagtacgtggagcacggacccctggatgtgtggctgcggcgggagaggggccacgtg
cctgtggcctggaaggtggcagtggcccagcagctggccagcgctctcagctacctggaa
gacaagagcctggttcatggtaatgtgtgtggccggaacatcctgctggcacggctggga
ctggcggagggcagcagccccttcatcaagctgagcgatcccggtgtgggcctgggcgcc
ctttccagggaggagcgggtagagaggatcccctggacagcccccgagtgcctgtcaggt
ggggccagcaccctaaccactgcagctgacaaatggggctttggtgtcaccctcctggag
atctgcttcgacggggaggcccctctgcagggccgcggcccttccgagaaagagtgcttc
taccagaagcagcaccagcttcctcagccctcatgcccggagctggccacactcaccagc
cagtgcctgacctatgaaccagctcagcggccctccttccgcaccatcctgcgtgacctc
actcagctgcagccccagaatcttgctgacgtcttggctgtgaacccggactcgcctgca
tcagaccccaccgttttccacaagcgctatttgaaaaagatccgggatctgggcgagggt
catttcggcaaggtcagtctgtattgctacgacccgactaacgacggcaccggcgagatg
gtggctgtgaaggccctcaaggcgggcgggggcccccagctccgcactggctggcggcgg
gagatcgacatcctgcgcacgctctaccacaagcacatcgtcaaatacaagggatgctgt
gaggaccaaggagagaagtcggtgcagctcgttatggagtacgtgcctctgggcagcctc
cgggactaccttccccggcacaacgtcggactggcccaattgctactcttcgcccagcag
atctgtgagggcatggcctaccttcatgcacagcactacgtccaccgagacctggctgcc
cgcaacgtgctgctggacaacgacaggctggtcaaaatcggggactttggcctagccaag
gctgtgcctgaaggccatgagtactaccgcgtgcgcgaagatggggacagccccgtattc
tggtatgctccagagtgcctgaaggagtgtaagttctactatgcatccgacgtctggtcc
ttcggggtcaccatgtatgagctgctgacctactgtgactccagccagagccccccttcg
aaattcatcgagctcataggcctcacccaagggcagatgacggtgctgaggctcactgag
ctgctggaacgaggggagaggctgccgcggccagagaaatgcccttgcgagatctacctc
ctcatgaagaactgctgggaggcagaggcctcattccgccccactttccagaacctcatc
cccattctcaagacagtccaggagaaataccaaggccaggccgcctcagtgttcaatgtg
tgctga
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