Lactococcus garvieae ATCC 49156: LCGT_0215
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Entry
LCGT_0215 CDS
T01618
Name
(GenBank) D-Ala-D-Ala adding enzyme
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
lgr
Lactococcus garvieae ATCC 49156
Pathway
lgr00300
Lysine biosynthesis
lgr00550
Peptidoglycan biosynthesis
lgr01100
Metabolic pathways
lgr01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
lgr00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
LCGT_0215
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
LCGT_0215
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
LCGT_0215
Enzymes [BR:
lgr01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
LCGT_0215
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Microtub_bd
Motif
Other DBs
NCBI-ProteinID:
BAK57728
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Position
214533..215864
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AA seq
443 aa
AA seq
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MKLTLHEIARVVGATNNWSELADTEIHNIEFDSRKIQKGDLFLPLKGARDGHTFIDTAFA
QGALATFAEQEVVQPHLRVEDCLEAFQKLAQYYLEKTAVEVIAVTGSNGKTTTKDMIQAV
LSEKYKTYKTQGNYNNEIGMPYTVLHMPDDTEKIVLEMGMDRLGDIDLLSKIAKPKIALV
TLIGESHLEFFGTREKIAEGKLGIKAGLRPDGELIVPADKIINKYLPTDTKITRFGPDED
IFVTKLIEHKDQLSFTTNFLDEEMTIPVPGKFNATNAMLAAYVGTLLDVDEVKIKHALSH
VALTRNRTEWKKASNGADILSDVYNANPTAMRLILETFQALPKNAGGRKLTVLADMLELG
EQAPGLHAGIAAAIDFSKMDHVYLYGDLMKYLRAELPEDKVSYFTDLNELTEAIQNTLQP
QDQLLLKGSNSMKLGTIVEELQN
NT seq
1332 nt
NT seq
+upstream
nt +downstream
nt
atgaaactaacactacacgaaatagcccgcgttgtcggcgcaacaaataattggtcagaa
ttggcagatacagaaattcataatattgagtttgacagccgcaaaatccaaaaaggcgat
ctctttttgccccttaaaggtgcaagagatggtcatacgtttattgacacggcctttgca
caaggagctcttgcgacctttgcagaacaagaagtagttcaaccccacttacgtgttgag
gattgtctggaagctttccaaaaattagcccagtattacctagaaaaaacagcagtagaa
gtaattgctgtgacgggatcaaatgggaaaaccacaaccaaagatatgattcaggctgtc
ctttcggaaaaatataagacttataagacacaaggcaattacaataacgaaattggaatg
ccttatactgttcttcatatgcctgatgatactgaaaaaatcgtgttggagatgggcatg
gatcgtctgggggatattgatcttctatctaaaatagcgaaaccaaaaattgctcttgtc
acgcttattggggaatcgcatttggaatttttcggtacacgtgagaaaattgcggaaggg
aagcttggaattaaggcgggcttgcgccccgatggcgaacttattgtgcctgcagataag
attattaataagtatttacccacagacacaaaaattacgcgttttggaccagatgaggat
atttttgtcacaaagcttatcgaacacaaggatcaactcagtttcaccacaaacttctta
gatgaagaaatgacaatccctgtgccgggtaaatttaatgcaactaatgcaatgctcgca
gcttatgtggggactttacttgacgttgacgaggttaaaattaaacacgcgctttcgcat
gttgccttgacacgtaaccggaccgagtggaagaaggcaagtaatggcgcagatattctt
agtgatgtttacaatgctaacccaacggccatgagacttatcttggaaaccttccaagct
cttccgaaaaatgcagggggacgtaaactcactgttcttgctgatatgctcgaactaggg
gaacaagctccaggacttcacgcaggcattgctgcagcaattgatttctccaaaatggac
cacgtttacctctatggcgacttgatgaaatatttgcgggcagaattaccagaagataaa
gtatcgtactttaccgatcttaatgaattgaccgaggcgattcaaaatacgcttcaacct
caagatcaacttttactcaaaggatctaacagcatgaaattaggaacaatcgttgaagag
ttacaaaactaa
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