Legionella hackeliae: LHA_1576
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Entry
LHA_1576 CDS
T03809
Symbol
pdhA
Name
(GenBank) Pyruvate dehydrogenase E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
lha
Legionella hackeliae
Pathway
lha00280
Valine, leucine and isoleucine degradation
lha00640
Propanoate metabolism
lha00785
Lipoic acid metabolism
lha01100
Metabolic pathways
lha01110
Biosynthesis of secondary metabolites
lha01210
2-Oxocarboxylic acid metabolism
Module
lha_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
lha00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
LHA_1576 (pdhA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
LHA_1576 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
LHA_1576 (pdhA)
Enzymes [BR:
lha01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
LHA_1576 (pdhA)
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Motif
Pfam:
E1_dh
DXP_synthase_N
Transketolase_N
TPP_enzyme_C
HTH_41
NifW
Motif
Other DBs
NCBI-ProteinID:
CEK10616
UniProt:
A0A0A8UT17
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Position
I:complement(1634487..1635560)
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AA seq
357 aa
AA seq
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MTTVASFEIPFVQFINEQGQPTDNLPSFAADKNVLKELYSIMVRTRTFDKKAIALQRTGK
MGTYAPINGQEAISTAIGHAMRKEDLFVPYYRDYAAQFQRGVKMSEILAYWGGDERGSQF
ACDSEDLPICVPIASQCLHAAGVAFAFKYRKQPRVAVVCIGEGGTSEGDFYEAMNVAGTW
KLPVVFIVNNNKWAISVPLSKQTAAETIAQKAIAAGFAGIQIDGNDVVACRQVISDAIEK
ARRGEGPTLIEALTYRLCDHTTADDATRYQPCEEVDSAKLKEPISRFKHYLEQQNIWDAK
QETELLEQSSKLVEQAVNDYLNRAPQPISSIFDYHYAELPDYLIEQRAIAMEEAAHA
NT seq
1074 nt
NT seq
+upstream
nt +downstream
nt
gtgacaacagtcgccagttttgaaataccattcgtccagttcattaatgaacaaggtcag
cctacagacaatttaccgtcttttgcagcggataaaaacgttctgaaggaactttatagt
attatggttcgcacaagaacttttgataaaaaagctattgcgcttcagcgtacaggaaaa
atgggtacctatgcaccaattaatggccaggaagccatttccaccgctattgggcacgca
atgaggaaggaagatctattcgttccttactatcgcgattatgctgcacagtttcagcgt
ggcgttaaaatgtctgagattttagcgtattggggcggcgatgagcgtggtagtcaattt
gcctgtgactccgaagatctaccaatttgtgttcccattgcttcccagtgtttgcatgca
gccggtgttgcttttgcttttaaataccgtaaacaacctcgtgttgctgttgtttgcatt
ggtgaaggcgggacttctgaaggtgatttttatgaagccatgaacgttgctggcacgtgg
aaattgcctgtagttttcattgttaacaataacaaatgggctatttccgtccccttgtca
aaacaaactgcagctgaaacgattgctcaaaaagctatagcagcgggatttgctggcatt
caaatcgatggcaatgatgttgtagcctgccgtcaagtaattagtgacgccatagaaaag
gcacgcagaggtgaaggtcctactttaattgaggcattaacctacagactgtgtgatcac
acaaccgctgacgatgccacacgatatcagccctgtgaagaagtagacagcgccaaacta
aaagaacctatcagccggttcaaacattatttagaacagcaaaatatctgggacgcaaaa
caagaaacagaattgctggaacaaagcagtaaactcgtagaacaagccgttaatgactat
ttgaatcgtgcaccgcaacctattagcagtatctttgattatcactacgccgagttgccc
gattatttaatcgagcagcgtgcaatagccatggaggaagcggctcatgcctga
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