Lactobacillus helveticus DPC 4571: lhv_0143
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Entry
lhv_0143 CDS
T00625
Name
(GenBank) D-alanine-D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
lhe
Lactobacillus helveticus DPC 4571
Pathway
lhe00470
D-Amino acid metabolism
lhe00550
Peptidoglycan biosynthesis
lhe01100
Metabolic pathways
lhe01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
lhe00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
lhv_0143
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
lhv_0143
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
lhv_0143
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
lhe01011
]
lhv_0143
Enzymes [BR:
lhe01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
lhv_0143
Peptidoglycan biosynthesis and degradation proteins [BR:
lhe01011
]
Precursor biosynthesis
Amino acid ligase
lhv_0143
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
ATP-grasp
GARS_A
ATP-grasp_4
CPSase_L_D2
TTL
Motif
Other DBs
NCBI-ProteinID:
ABX26408
UniProt:
A8YWP6
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All DBs
Position
144431..145513
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AA seq
360 aa
AA seq
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MTKKTQVGLIFGGNSSEYEVSIVSCRNIYKAIDKEKFDVHPIWITNEGYFANEEESFKVL
EDPSYQVKNPHKVHNISNLIELENLPEIDVFFPIVHGNLGEDGVLQGLFRLMNKPFVGDD
VLAAAVTMDKEFTKILAQRVGVPVADWITIKRFEYDDKNNDKLDYEKVAEKLGRDMFVKP
SNQGSSVGVSHVTNADEYAAALKEAFKYDDKVLVEETVPGTEVETAVLGNDKPIVAGVGQ
ITNAKGSFYSYKNKYDDNSTSKLQIPADLPQEIIDTVRRNARKVYEVTECSGMARIDSML
TPGGKVVLTEVNALPGFTNISMYPKLFEEAGVPYTELITRLIEVGMERFDHKKTLLHKHD
NT seq
1083 nt
NT seq
+upstream
nt +downstream
nt
atgactaaaaaaacacaagttggattgatttttggtggtaactcatcagaatatgaagta
tcaattgtttcatgtcgtaatatttataaagcaattgataaagaaaaatttgatgtacac
ccaatttggattactaatgaaggctactttgcaaatgaagaagaaagtttcaaggtttta
gaagatccttcataccaagtaaagaacccacacaaggttcacaatatttctaatttaatt
gaattagaaaacttaccagaaattgatgtctttttccctattgttcacggtaacttgggt
gaagacggcgttttacaaggtttattccgtttgatgaataagccattcgttggtgatgac
gtcttggctgctgccgtaaccatggacaaagaatttaccaagattttagctcaaagagtt
ggcgttcctgttgctgactggatcacaattaaacgttttgaatacgatgacaaaaataat
gataaacttgattatgaaaaagttgctgaaaaacttggccgtgacatgtttgttaagcca
tctaaccaaggttcatcagttggtgttagccatgtaactaacgctgatgaatatgcagca
gcattaaaagaagcatttaagtacgatgacaaggtattagttgaagaaactgttcctggt
actgaagtagaaactgccgtactaggtaacgacaagccaattgtagcaggtgtgggacaa
atcaccaatgcaaaaggctcattctacagctataagaacaaatacgatgacaattcaact
tctaagttacaaatccctgcagatttgccacaagaaattattgacaccgtaagaagaaat
gctcgtaaagtttatgaagttaccgaatgtagtggtatggctagaattgactctatgctt
actccaggtggtaaagtagtattgactgaagttaatgctcttccaggctttactaatatc
agtatgtatcctaagttgtttgaagaagcaggtgttccttacactgagttaattactcgt
ttgattgaagtaggaatggaacgttttgatcataagaagactttgcttcataagcacgat
taa
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