Lactobacillus helveticus DPC 4571: lhv_0282
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Entry
lhv_0282 CDS
T00625
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
lhe
Lactobacillus helveticus DPC 4571
Pathway
lhe00300
Lysine biosynthesis
lhe00550
Peptidoglycan biosynthesis
lhe01100
Metabolic pathways
lhe01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
lhe00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
lhv_0282
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
lhv_0282
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
lhv_0282
Enzymes [BR:
lhe01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
lhv_0282
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
RecA-like_ORC2
Motif
Other DBs
NCBI-ProteinID:
ABX26511
UniProt:
A8YXI0
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All DBs
Position
287150..288517
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AA seq
455 aa
AA seq
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MKMQMAEIAKDLNTTCEGDDKTVITSVAFDSRKITTGGLFVPLEGERDGHDFVAGAISNG
ASATLWKKGHPNKPENITVIEVDNPLTAMQDLARYYLRKVNPTVVGITGSNGKTTTKDMI
AAVLSKRFNVHKTQANFNNEIGVPMTILEMKPNTEILVLEMGMDRPGQLHHLSELTHPDV
AVITMIGEAHIEFFGSRDKIADAKMEITDFLREDGEFIYNGDEPLLQERAKKLDQAKATF
GFRDEDTVHATGFKSYMHHATFTINDSEQKFSIPMIGKHNVSNAMAAISVGHHFGESDEE
IASSLSNFKPTANRMEWEKGDAGEAIMSDVYNSNPTAVRAVVTSFGQVEVKDGGRRIAVL
GDMLELGKKSPELHAGLSDTLDPQIINEVYLYGSEMKNLYDALQDKYEPENLHYYTQDQM
DHMINDLKNDIKPDDIIVLKGSHGMHLENVLARLR
NT seq
1368 nt
NT seq
+upstream
nt +downstream
nt
atgaaaatgcaaatggctgaaattgccaaggatttaaatactacttgtgaaggcgacgac
aaaactgttattacttctgttgcctttgactccagaaagataacaactggtggtttgttt
gtaccgcttgaaggtgaacgtgatggacatgatttcgtagcgggtgctattagtaatggt
gcttctgctactttgtggaaaaaaggccatccaaataagcctgaaaatatcacagtaatt
gaagtagataatcctcttactgctatgcaagatttggcgcgttattatttgcgcaaggtt
aatccaactgtagtaggcattaccggttctaatggtaagactactactaaggatatgatt
gctgcagttttatctaagcgttttaacgtacataagacacaagctaactttaataatgaa
attggtgtaccaatgaccattctcgaaatgaaaccaaatactgaaattttggtacttgaa
atgggtatggatagaccaggtcaattacatcatttgagtgaattgactcatccagatgta
gctgtcattactatgattggtgaagctcatattgagttctttggtagccgtgacaagatt
gctgatgctaagatggaaatcacggactttttgcgtgaagatggtgaattcatttataac
ggtgatgaaccattgttgcaagaacgtgctaagaagcttgatcaagctaaagctacattt
ggcttcagagatgaagatacagttcatgcaactggattcaagagctacatgcatcatgct
acttttacaattaatgattcagagcaaaagttctcaattccaatgattggtaagcataat
gtttctaatgcaatggcagcaattagtgtaggacatcactttggtgaaagtgatgaggaa
attgcttcatcattgtctaactttaagccaactgctaaccgaatggaatgggaaaaaggc
gacgctggcgaagctattatgagtgatgtttacaactcaaatccaactgctgttagagcg
gttgttactagttttggtcaagttgaagttaaagatggtggtcgcagaatcgctgtactt
ggcgacatgttggaattaggtaaaaaatcacctgaacttcatgccggattaagcgatact
ttggatccacaaatcatcaatgaagtgtacttgtacggctctgaaatgaagaatttgtat
gatgctttgcaggataaatacgagccagagaatttacattattatactcaagatcaaatg
gatcatatgattaatgatcttaaaaatgacattaagccggacgacattatcgtattgaag
ggttcacacgggatgcaccttgaaaatgtcttagcccgactaagatag
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