Leptotrichia hongkongensis: JMUB5056_0090
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Entry
JMUB5056_0090 CDS
T06709
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
lhg
Leptotrichia hongkongensis
Pathway
lhg00300
Lysine biosynthesis
lhg00550
Peptidoglycan biosynthesis
lhg01100
Metabolic pathways
lhg01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
lhg00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
JMUB5056_0090
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
JMUB5056_0090
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
JMUB5056_0090
Enzymes [BR:
lhg01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
JMUB5056_0090
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
ZoocinA_TRD
Motif
Other DBs
NCBI-ProteinID:
BBM58523
UniProt:
A0A510L7L3
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Position
95295..96674
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AA seq
459 aa
AA seq
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MNKAEVFQSFFNKVEISDFEINNISINSKELDKNDIFVAIRGGNNFVNEALEKGAFAVYD
SKTLKIDEKYANRAFLVNDSVEFLQNFAREWRKNLDIKVIGITGSNGKTTVKDMIYHLLS
QKYKGKKTEGNYNNHIGLPFTLLRAEEDDKFIILEMGMSGFGEIDLLGQIALPDINVITN
IGESHLEFLKTKENVFLAKTEIIPYIKNTLVINGDDDYLKNVKAENIEVVKALNLGSNEF
REKTSDFYYGDVHFNEGGTDFFLKYFGKICQSTVERNYKTNVLGEHNVLNLVMAIAVAKQ
FGMEDKIISEAVKNIGLTGMRFQIIENGDTTYINDAYNASPMSMEKSLETFSQIYNDRLK
IMVLGDMLELGENELELHSNLFNTIKTTKFDKLYLFGERMKSLFEKIKENVDNENLKNKE
FGHFDEKEEIKEKIRQISEQKAVLLKASRGMRLEEIIEK
NT seq
1380 nt
NT seq
+upstream
nt +downstream
nt
atgaataaagctgaagtgtttcaaagtttctttaataaagtagaaatatcagattttgag
ataaataatatttcgattaactcgaaagaacttgataaaaatgatatttttgttgccatt
agaggtgggaacaattttgttaatgaagcattggaaaaaggtgcttttgctgtttacgac
agtaaaactttaaaaatagatgaaaaatatgctaatcgtgcatttcttgtaaatgacagt
gttgaatttttacaaaattttgctagagaatggcgaaaaaatttagatataaaagtaatt
ggaattacaggaagtaatggaaaaaccactgtaaaggacatgatttaccatttgctttca
caaaaatataaaggaaaaaagactgaagggaattacaataatcatattggattgcccttc
actttgttgcgtgctgaagaagatgacaaatttattattctagaaatgggaatgagcggt
tttggagaaattgatcttcttgggcagattgcattgcctgatattaatgtaattaccaac
attggagaatcacatctggaatttttaaaaacgaaggaaaatgtatttttggcaaaaacg
gaaattattccgtatattaaaaatacacttgtaatcaatggagatgatgattatttaaaa
aatgtaaaagctgaaaatattgaagttgtaaaggctttgaatctaggaagtaatgagttt
agggagaagacgtctgatttttattatggagacgttcattttaacgaaggcggaactgat
ttttttctgaaatattttggaaaaatttgtcaaagtacggttgagagaaattataagacg
aatgttctaggagaacataatgtattaaacttagttatggcaattgctgtagctaaacaa
ttcggaatggaagataaaataatcagtgaagctgtgaaaaatattggcttgactggaatg
cggtttcaaataattgaaaacggcgatacaacatatattaacgatgcctataatgcaagt
ccaatgtctatggagaaatcacttgaaacattttcccaaatatataacgacagactgaaa
ataatggttctaggagatatgctggaactaggagaaaatgaactggaacttcatagtaac
ctttttaatacaataaaaactacaaaatttgacaaactttatttatttggagaaaggatg
aaaagcctattcgaaaaaataaaggaaaatgtggacaatgaaaatttaaaaaacaaggaa
tttggacattttgatgaaaaagaagaaataaaagaaaaaataagacagatttctgaacaa
aaggcagtgctgttaaaagcatcacgaggaatgagattagaagaaatcatagaaaaataa
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