Leptopilina heterotoma: 122508048 Help Entry 122508048         CDS       T08438                                  Name (RefSeq) E3 ubiquitin-protein ligase UBR4   KO K10691   E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27] Organism lht  Leptopilina heterotoma Brite KEGG Orthology (KO) [BR:lht00001]  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:lht04121]     122508048 Enzymes [BR:lht01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      122508048 Ubiquitin system [BR:lht04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    UBR box proteins     122508048 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  E3_UbLigase_R4 E3_UBR4_N UBR4 zf-UBR Motif Other DBs NCBI-GeneID:  122508048 NCBI-ProteinID:  XP_043477057 LinkDB All DBs Position Unknown AA seq 5228 aa AA seqDB search MAAKSGGSVDWSSIIKPILSASYGSFNKNEIIDLVKAIVKSESEFSNHDESHEAFYTSFA ALIADYISGYANSLSKNQIPLVWQACKILLVYLVGKLPQNQTQPGDGSSTILTTKQLLLA IRSLCVGQSLLVKTEEVALVTILRNAKLPSSATTSTTTTATGTTTPLSTNGEKESNQQHI KEAKRSRSDLSSNILEQLTMPLQEFIPSLSARIDVTSDGTKLPENVSNEQASDIKMMFTA NNIGTLQNISAGDTLLDMCTNLPHLSRYSRKYQTFLNRKSFCLPSNHSEAHTIRYSLHSV VNDINIVHSVVSLPILEPLTPVKLEKLSLLTMSCLYCSIANATASSIVGITNAVSPKCST NQAGQATGNQSGKSAEEEYDTLAINVVERSLEIFSLVSNIIKYSTRAGGHILQNHLLIGV WLLVAGLQAQLSVSSVSAVDKSKEEKGKSPSKARDGTGRINLMKVQQGFGVLSVALASHA LTLMSALLEDVSVEAGPNRPPTPEPAPLDILATVTALQRAATFFQAAPLNHLLFYLATIS YRKACTLKRVQKHSLEGDTLSQSDSTTYYEDLLSCSENSADEEEDSEPILGLWFEETLAP SDSQSSNASKETNNEPTVERATTAIVPDNREPHGYISLATQIFQFMNQHLLGSRSIYVRE YVMNGLVEQQMVILAAIIRDLDHEAARTETGTISVFYGATLGAMYSEFSQALSLYTHNLL TRNTLSETLQNTLLQHLGVSPWATENANSSSWPLQVYPRTLSVLAQILLLKPQLEKEAAC ISIWHRLVTTMVENVCNSPANSDAENEDLNVEHAQLVLFLFHSLNLMQKKSVLLVTGSGA VRCSEAVKTPMKDSQILHLSRLLLLLEYMMKHLYDAPSSLLEQVQWNLLSGTSLVCDAKE GNKQASRIYTPWKEIEDNYKKFTPQDELSIKPKFYNLTIADLNNQDTPKLDGLACNFVLG TSDKMKYPLLVDALIDILNIINQTSIPRKQSPDAKDKMTFTGLCATQYCFSICWRLLLML PPSTAYMDELALGEEIPSTPMLLYSLIWGPRAACKAFTGWMKDCLVKQGMYTQYAENLLK TISSTVTSLKYDVTLAKNAIKALIPEVKEEKILPKNSLPKLSSLTILSAVIGKLQVIMDE SLYKTSNDNIEQSKNQSQESITSNINKMLIDILPHVLKLTRSVILACKSSVLYQAQEASD QCKYNARDFSVLDIIIAMDGITSMTGWSLETSMVNLLSSNVRSALDKWKSINAAHIPWNT YVNDIIPAESYILATINHHINPLSEFGTFSINSSLKNLLYSLVNFIMEYVNPISGLEISE ISQIREEAIDILIPLTIDARTDYVQEMASKTLGKILGDTDSEPRQLRVHLFILSYTYDLI IDYTSNSEEAINITIDEKILTNYIKYWEYLLDKPVGYKALAEFFAPDTNRKLMSILLSIA SPLASQQFGTHVLHFFNKLFKTAEKVNDGSLDRLCSSVANLSTVENEKLQTWLRHVILGE RKERKEEGTETWQNILVDGKVNQNNHYQALEENNQLLQSLTNYIVKENSGNNVSVTMLQA LIPLGYHILSSVEGVSFTDLMQVMSTLADVGTDKGHKLLFKAATGWIEVCKQQLMSDPQL EKPSGYIEAGCCVLNYIADVVSAVCPQNYSQDRATSPPWEGATPVNDVNDSDWNEELVHE DDDSAAEDSDEDSLCNKLCTFTITQKEFMNQHWYHCHDCNMVDGVGVCTVCARVCHRGHD VTYAKYGNFFCDCGAKDDASCQALMKRSPQSSEHQIVGNNIAYGTGNSDTTHLTSSLRRR ASSPIHEKSERSSKDRQKLSALSKQLEGSKDWILAQLWSSELISSLVELTSNLVPAVEAS CRKHSAVGCHSRGQLALRQLHLLDKKFEHTDQLMLPTLGSQEGAFENVRMNYSGDQGQTI RQLLSAHMIRRVAMCCLSSPHGKRQHLAVSHEKGKITVLQLSTLLKQADSSKRKLTLTRL ASAPIPFTVLSITGNQWNEDFLAVCGLKDCHVLTFNSSGTVSDHLVLHPHLETGNFIIKA LWLPGSQTQLALVTADFVKIYDLSKDALSPQYYFLVPTGKIRDCTFIHAEDGMFHLLLMS SAGYIYSQAMDEESLAKHGPFYVTNTLDIYHPEIKDNGQVGGGGVSIYYSHALQLLFFSY ACGKSFIAPLKYMNLEINIVFMINLANKTNGNKSNNNQPQPLCQWSEIANHPGLVCSVLQ SSNNPVILMIKPETIMIQEIKVVPAKAKIMDIVAIRHSSSNAEHRTTLILLCEDGSLRVY MAAMDQTGFWMSPNVQPVGTIATIKQTKKKKAMKTGKPSGSVVFPVDFFEHCQSMNDVEF GGNDLLQIYNVAQIKHRLNTTGMYVASTRQLGFNVEVNNNDPTLVMTGFRVQLGNQDIQR APLFVEIFGRSVRIMLTRSRWFDIPLTREESLQADKKLVITFGPSQDAEGVIMVDSIKVY GKTKDAFGWPEEPEEITAGQSTSAPAATGAPVNNENESTLVSPVTLTSIDKMTSSILQVL VSSFTLSSSDENKSSLKSTAIEVASNLLTLPIPQQVQVHTTSLLAALHNSKLSYHSHKDQ VLLSHVLDSLSSMQKINDPRDIDAENFYRLVLIVRNIAVARPGNLAKFADQHSAKSIDIS SIPVFEKDRLDSQSTTDKNQHLVVQLMDVLWSLYAAYPKNMALAPVVVPGLTHTEATIHA IVEIIHAFTTCDIEGNTPLAAKLYLQLLLSSDTSISFSAKQAIIRVLRPRYKRRRVFIPS PPHCSTPGAPMETEEKREISVQSSQDSADVEQQYEVEANDPMALSGNDDNRASGGRAGNH PLEALLGPGGFPQLLDMPPADDDEVMVELAIALSLQDQQRAGNSQVPQQGFPQGLANIPG LQGLENLNGPELDRIQALAVQGLSQAVERLNVAVLGQEGSHYSDTTASAGGSDDEGSTAA TDGSTLRTSPAEQGGSGGSKGSESGGSDSGGSAVDSITGEHNVSGRSSAYGDNAPESIPS MNIGQPSRSENSSVGAATAFSATEQEQEQEQEQEQVLEQDTDNVGENTMNLHDIRLLLLD KLMQFIPDLTNVSGVLAIPFMQVILMLTSDLDGMDERDKTCVERLLQILVKELEMENPDT SDICQRSNKREVHLVIMRLLSVLMSRSKGSTKSQVENPNFVSQTTAAILSNNGVIDYCLN LLKALLDYWKNTSNEEAGNVIGGQLLKEHLIASPPDMSPFFLRQYVKGHASDVFEPYPQL LTEMALKLPYQVHKYAENSVVQPEFDQQAWFYYLCEYMMSYQTPFVRRQVRKLLLFICGN KDKYRQLRDLHSLVSHVQSVQQCCNTGGYDPLNSHPLAINLPYDSLVELIEHLKSCVEVA TSRTGNWQRFCSKHNTVLSYLFTISTLLDEGVSPTVLQLLQCAICSSKFKEVKSKDTKST TSSTKERRDREKSEDSDTEAKFEEAQCVFLVKQIQQQVSPALLTKFIQTFLLEANNTNVR WQAHSLILAIYKNCGPSNQEILLDLLWRLWPLLPMYGRKAAQFVDLLGYFSLKTPHTGNK MHVYMEQAVAVLHAENELLSRHPNANLYANLAQFVELDGYYLESEPCLVCNNPEVPMSTI KLSSIKVDSKFTTTTQIVKLVGSHTISRITLRIGDLKRTKMVRTINVFYNNRSVQAVVEL KNKPAMWHKAKKITLAQGQTEIKIEFPLPIVACNLMIEYADFYENIQASSETLQCPRCSA SVPANPGVCANCGENVFQCHKCRAINYDEKDPFLCHACGFCKYAKFDYTLTGRPCCAVDP IESDEDRKKTVATINTLLEKADRVYKSLISNKPTLEMLLVKISEHRSDRSLEDGGVVAGG STQVNRAIQLLAQKYCGECKTSFEELSKIIQKVLACRRELVAYDRNQRGLAVIQHQQAST SDGSVEPIAPNAGRCYGCASAATEHCLTLLRALATNQAAREVLCKHGLIQELVEHNLRKG TIQMQEEVRQLLCLVTRDNSESTKELCALLTNRVTMTLKGRIATHDLSMAVRHEMSLLAA LVQKEDSCWEQKLRCVMQLFLLACKDSKSPVVMDSVILPCMKILQSVIKPEQPVSKKNKD KSTESLATIQPPAGISIDIGKWLSGDSMYTYANWLERVPTRKSEAGPSKQLTKEEARIVY LMEKYGHRWHNRCHHLRDMKSLKLVDGAWLKEVLFNPSSRLARQVACTMIESLCQGMERK KELLVLLTNYLEEVHIAGESSAEFLSLYQSLIRQSPWKQFLAVKGVLTLLAELLTREIED LHRLEETTLTSDLAQGYSLKMLTELLATFLEQENIKQHYKGRLVGAVLNGYLSLRRLVVQ RTRLIDDTQEKLLELLEEMTTGTEEETKAFMAVCVETIQKYSPQDVRTPVFIFERLCSII YPEENDVGEFFLTLEKDSQQEDFLQGRMLGNPYSSLEPGLGPLMRDVKNKICQDCELVAL LEDDNGMELLVNNKIISLDLPVKEVYKKIWVVEGGECDAMRVVYRMRGLLGDATEEFVET LNANSEQEVNNEEVYKMANVLADCGGLEVMLNRLAAIQDVSRARPLLQVLLKLFRLSVKV KKNQEVLSRPELKAVSVLLDVLQRCLETESDSSQAKITEQLLDIMETILENAAAQPLSSF EEFSKTLGGADHIKTLLSCTQSSAVRQCNNVLMHLARVLAALTYGNEEKMALLCDYFKPV LNFYKFDFEHTTEDDQKLELFCILTQGIERNAIGNTLKDHIINMGIVKDAFEYITMHAPC VKPTLLRTDSDELKDFISKPSLKYILRFLTGLATEHEPIQLSVSPAIISIIHRLEQVSSD EHVGSLAENLLEALCTNKKVSELIEEARQHTRSEKKRLAMAMRERQLGALGMSTNDKGQV TASKTILQQMEDLGDETGLICVICREGYKFKPNMVLGIYTFTKRCNVEEFETKQRKTIGY TTVTHFNVVHVDCHMSAVRLARARDEWESAALQNANTKCNGLLPLWGPQVPESAFASCLA RHNTYLQECTGHRDISYSSTIHDLKLLLLRFAQEKTFHEDTGGGGPQSNMHIIPYLIHMA LYVINTTRSAAREEKAHMSYLHSTASSSWLDSCYEADGPFYQCTLSLLVMPPSQWNKFRI THLRRLIILAQQRYTSPSLSTKNLTDVTVKDYSVYKSVLIFFGLVDCIYNTFFKKVVVTS DEQWPSILAEYIRHNDEALLKASERVLATYRDELLPCESFEEYCDVVGLIEDVTDISSYI SKVLKDLA NT seq 15687 nt NT seq  +upstreamnt  +downstreamnt atggcggcgaagagcggtggctccgttgactggtcgtcaattattaagccaattttatct gcatcttatggttcattcaacaaaaatgagattattgaccttgttaaagcaattgtcaaa agtgaatcagaattttcaaatcacgatgaatcccatgaggccttttatacgtcttttgct gctttaattgctgattacatcagtggttacgcgaattcattatcgaaaaatcaaattcca cttgtttggcaagcatgcaaaattctattggtctacttagtgggaaaattgccccaaaat caaacccaacctggcgatggatcgtcaacgattttaacaacgaaacaattgcttcttgca attcgttcactttgtgttggacagtcacttctcgtaaaaacagaagaagttgctctagtc acaattctgagaaatgcaaaattaccatcatcagcaacaacatcaacaacaacaacagca acaggtacaacaacgccattatcgacaaatggcgagaaagaatcaaatcaacaacacatc aaggaagcaaagagaagtcgaagcgatttgtcgagcaatattcttgaacaattaacaatg cctcttcaagaatttattccttcattatcggcgagaattgatgttacctccgatggaacg aaactacctgagaatgtttccaacgaacaagcctcagacataaagatgatgttcacggcg aataatataggaactctccaaaatatcagcgctggagacacattattagacatgtgtaca aatcttccgcatttgtcacgctacagtcggaagtatcaaacttttttaaatcgtaaaagt ttctgcctcccttcaaatcattcagaagcgcatacaatacgttacagtcttcattcagtt gtgaatgatataaatatcgttcacagtgttgtatcattgccgattctcgagccattgaca ccagtgaaattagagaaattatcactactcacaatgtcgtgtctctattgttcaattgca aatgcaacagcgtcgagtatcgttggcataacgaatgcagtgtcaccgaaatgtagtaca aatcaagctggccaagcaactggcaatcaaagtggtaaaagtgccgaggaggaatacgat acattagcaataaatgttgtggagagaagtttagaaatattcagtctagtctcaaatata ataaaatacagtacacgagccggtggtcatattctgcagaatcatcttttgattggagtt tggcttcttgttgccgggttgcaggcgcaattgtcagtgagtagtgtgagtgcggtggat aagagtaaggaggagaagggaaaatcgccgagtaaggctagagatggaactgggaggata aatttgatgaaagtacaacagggttttggtgtattgtcagtggcgttggcgtcacatgcg ttgacattgatgagcgcacttttggaggatgtttccgtggaggcgggtccgaatcgtccg ccaacaccggaaccggcgcctttggatattctcgcgacagtgacggcattgcagagggcg gcgacatttttccaagcggcgcctcttaatcatctgcttttctacttggcaacgataagt tacaggaaagcttgcaccttaaagcgagtgcagaaacattccctcgagggcgacacattg agtcaatcggactcgaccacgtactacgaggatttgttgagttgctcggagaattcggcc gacgaggaagaagacagtgaaccgattttgggactttggttcgaggagactttggcacct tcagacagtcagtcgagtaatgcctcgaaggagacgaataatgagccgactgtcgagaga gcgaccactgcgattgttcccgataatcgtgaaccacacggatatatttcactggcaacg cagatatttcaatttatgaatcaacatttactgggaagtcggagtatttacgtgagggaa tatgtcatgaatggattggttgaacagcaaatggttattctggcggctatcataagggat ttggatcatgaggctgcgagaacggaaacgggaactatatctgttttttatggcgcaaca ctcggagcgatgtattcggaattctcccaagcgctcagtttgtacacacataatttactg acgagaaatacattgagtgaaactctgcaaaatacgcttctgcaacatttgggagttagt ccctgggcgacggaaaatgcgaatagttcctcttggcccctgcaagtttatccgaggaca ctcagtgttctcgctcagatacttttactaaaaccacaactcgaaaaggaagcagcgtgc ataagtatttggcaccgattagtcacgacaatggtagaaaatgtttgcaattcaccagcg aattctgatgctgaaaatgaagatttgaatgtggaacatgcgcaacttgttttgtttctc tttcattctctgaatttaatgcaaaagaaatctgttttgctcgtaacgggaagtggcgca gttcgatgcagcgaagctgtcaaaactcccatgaaagattcacaaattcttcatctatcg cgcttgttacttctactggagtatatgatgaaacacctttatgatgctccgtcttctcta ctcgaacaggtgcaatggaatcttttatcgggaacgagtttagtgtgcgacgcaaaagaa gggaataaacaggcatcaagaatttacacaccatggaaggagattgaagacaattacaaa aagttcacaccacaagatgaattatcaataaaaccgaaattctacaatttaacaattgcc gatcttaataatcaagatacaccgaaactcgatggtttggcctgtaattttgtcctcggc acatcggacaaaatgaaatatccccttcttgtcgatgcattaattgatattctcaatatt atcaatcaaaccagtattccaagaaagcaatcgccagatgcaaaggataaaatgacattc accggtctatgtgcaacgcaatattgtttttccatttgttggcgattacttctcatgcta ccaccatcgacagcctatatggacgaattggcattgggcgaggaaattccctcaactcca atgcttctttattcattaatctggggaccgagggccgcttgtaaagcattcaccggctgg atgaaggattgtctcgtcaaacaaggaatgtacacacaatatgcggaaaatttattaaaa acaatttcgtcaacagtcacatcattgaaatatgacgttacactcgctaaaaatgcgata aaagccttaataccagaagtgaaggaggagaaaatattaccaaagaattccctaccgaaa ttgagttccctgacaatattgtcggcagtaattggcaaattacaagttattatggacgaa agtctgtataaaacatcgaatgacaatattgagcaatcgaaaaatcaatcacaagagtca ataacttcgaatattaataaaatgctaatagacattttacctcatgtgttaaaattaacg agatcagtgattttagcatgtaaatcgagtgttttgtatcaagctcaagaagcttcggat caatgtaaatataatgcgagagatttttccgttcttgacattatcatcgcaatggatgga ataacatcaatgactggttggtcactcgaaacttcgatggtgaatctactttcaagcaat gttcgctcggctctcgataaatggaaatctataaatgcggcccacattccttggaatacg tacgtcaacgatattataccagctgaaagctatattctagccacgataaatcatcatatt aaccccctctctgaatttgggacattttccataaattcctcgctgaaaaatctactctac tcgctcgtgaattttataatggagtatgttaatccgatctcgggtttggaaatatcggaa atctcccaaattcgcgaagaggcgatcgatatactgataccgttgacaatcgatgcgcga actgattatgttcaagagatggcatcgaagactttggggaaaatactcggcgatacggac agtgaacctagacagttacgagttcatctcttcattctttcgtatacttacgatttgatt atcgattacacgagtaatagtgaggaggcaatcaatataacgatcgacgagaaaatattg accaactatatcaagtactgggagtatttgcttgataaaccggttggttataaggctctc gcagaattctttgctccggatacaaatcggaagttgatgtcaatattgctgtcgattgcc tcgccactggcttcgcaacaatttggaacgcatgttttgcattttttcaataaattattc aagactgcggagaaagtgaatgatggatctttggatcgattgtgtagttcggtggcgaat ttatcgacggtcgagaatgagaaattgcaaacttggttgagacatgtgatacttggggag aggaaggagcgaaaggaggaggggacggaaacttggcagaatattctcgtggatggaaag gtgaatcagaataatcattatcaagcgctggaggaaaataatcagctgttacagtcgttg acgaattatatcgtcaaggagaatagtggaaataatgtatccgtgacgatgctccaggcg ttgattcccttgggctatcatattctgtcgagtgtcgagggtgttagcttcacggatttg atgcaagtgatgtcgaccctagcggatgtggggaccgataaaggtcataagttattattc aaggcggcgaccggatggattgaggtctgtaaacagcagttgatgagcgatccacaactt gagaaaccatcgggttatattgaggcgggttgttgtgttttgaactacattgcggatgtg gtttccgccgtttgtccgcagaattattcgcaggacagggcgacgagtccgccttgggag ggagcgacgccggtgaatgatgtgaatgacagtgattggaatgaggagttggtgcatgag gacgatgacagtgcggcggaggattcggacgaggatagtctttgtaataaactttgtact ttcacgataactcagaaggagtttatgaatcagcattggtatcactgtcatgattgtaat atggtggatggagtgggggtttgtacggtttgtgctcgggtttgtcacaggggacacgat gttacctatgcgaagtatgggaattttttctgtgactgtggagctaaggacgatgcctcg tgtcaggctttgatgaaacgaagtccacagagttcggagcatcagattgtggggaataat attgcctatgggacggggaattcggacactacgcatttgacgagtagtttacggaggaga gcgtcgagtccgattcacgagaagagtgagcgatcgagtaaggataggcagaaattgtca gcactttcgaagcaactggagggatcgaaggactggattttggcgcaattgtggtctagt gaattgatatcgtcgttggtggagttgaccagtaatttggtgccggctgttgaggcgtct tgtcgaaaacattcggctgttggctgccactctaggggtcagttggcgctgagacaactt catctgttggataagaaattcgagcatacggatcagttgatgctgcctacgttgggctcc caggagggggcttttgagaatgtgaggatgaactactcgggcgatcaggggcagacgatt agacaattactctcggcgcatatgatcaggagagtcgccatgtgttgcctctcgtccccc catggcaaacgacagcatctcgccgtttcacacgagaagggaaagatcacggttctacaa ttgagtactttactaaaacaggccgattcgtcgaaaagaaaattaaccctcactcgtttg gcctcagcgccgattccatttacagttttgtcaataaccggaaatcagtggaacgaggac tttctggcggtgtgcggactcaaggactgtcatgtcctgactttcaacagttcgggaact gtcagtgatcacttggtactgcatccgcatctagagaccggaaacttcatcatcaaggcc ttgtggctcccaggctcgcagacccaactggcccttgtcaccgcggactttgtcaaaatc tacgatctcagcaaagacgctctaagtcctcagtactacttcctggttccaacggggaaa attcgtgactgtactttcattcacgcggaagatggaatgttccacctgctgctaatgtcc tcagccggttatatctacagtcaagcgatggacgaagagagtctcgcaaagcacggacca ttttacgtcacaaacacgctcgatatctatcacccagaaattaaggacaacggtcaagtg ggaggcggcggtgtctcgatctactactcccacgctttgcaacttctcttcttcagttac gcctgcggcaagagtttcatcgccccgttaaaatacatgaatctcgagataaatatcgtc ttcatgatcaatctagcgaacaaaaccaacggcaacaaatcaaataacaatcaaccccaa ccactttgtcaatggagtgaaattgccaatcatcccggtttggtctgctccgttctccaa agcagtaataatcccgtgattctgatgatcaaacccgaaacaataatgatacaggaaatt aaggttgtgccggcaaaggcgaaaataatggatattgtcgcgattagacactcgagttca aatgcggagcatagaacaacgttgattttgctctgtgaggatggaagtttgagagtttat atggcggcgatggatcagacgggattttggatgtcgccgaatgttcaaccggtgggaaca attgccaccattaagcagacgaaaaagaagaaggcgatgaaaacgggaaaaccatcggga tcggtcgtatttccggttgatttcttcgaacactgtcaatcgatgaatgacgttgaattc ggtggaaatgacttgctgcagatttataatgtggcacaaattaaacatcgattgaatacc actgggatgtatgttgcatcgacgagacaacttggttttaatgttgaggtcaataataat gatcccactctagtcatgacgggatttagagttcaattgggaaatcaggatattcaacgg gcacctctctttgttgaaattttcggcagaagtgtcagaataatgctgacgcgaagcaga tggttcgatattcctttaacaagagaggaaagcttgcaagcggataaaaaattagtcatt acttttggtccatcgcaagatgccgagggcgtcattatggtcgattcaattaaagtatat ggaaaaacgaaagatgcctttggttggccagaagaaccggaggaaattaccgctggacaa tcgacatcggctcctgctgcaactggagcacctgtcaataatgaaaatgaaagtacactt gtctctccagtgacactaacatctattgacaagatgacgtctagtatcttgcaagttcta gtttcctccttcactctctcttccagtgatgaaaataaatcctcattaaaatcaacagca attgaagttgcctctaatcttttgacactaccaattccacaacaagttcaagtgcacaca acttcgcttctagctgctctacacaattcaaaattatcctatcactctcacaaggatcaa gtacttctgtcgcatgttctcgattcattgagttcaatgcaaaaaataaatgatccacgt gacattgatgcggagaatttttaccgacttgttcttattgttcgaaatattgccgttgct cgtcctggtaatttagccaagtttgccgatcagcattctgctaaatcaatcgatatatcg agtattcccgttttcgaaaaggatcgtcttgattcacaatcgacgactgataagaatcaa catttggtggtgcaattaatggacgttttgtggtcactttatgctgcgtatccaaaaaat atggccctggcgccagttgtggtgccaggtttgactcacacagaggcaacaattcacgcg attgttgaaataattcacgcctttacaacctgcgacattgagggtaacacgccattggca gcgaagctttatcttcaattattattatcctcggacacgagtatcagctttagtgcaaag caagcaatcattcgtgttttgagacccagatataaacgtcgacgtgtttttataccgagt cctccacattgcagtactccaggtgcgccgatggaaacagaggaaaaacgagaaatttcg gtgcaatcgtctcaagattcagcggacgttgaacagcaatatgaagttgaagcaaatgat ccaatggcgttgagtggtaacgatgataatcgagcatcgggaggccgagcgggaaatcat cctctggaagcgcttcttggtcctggaggatttccacaattgttggatatgccaccggct gacgacgatgaagtaatggttgaattggcaattgccctcagtctacaggatcagcaaaga gctggtaacagtcaagttcctcagcaaggctttccacagggtcttgccaatattcccgga cttcagggtttggagaatttaaatggacccgaattagatcgaattcaagcgttggccgtt cagggtctttcgcaggctgtcgagagattgaatgtcgccgtcttgggtcaagaaggaagt cattattcggacacaacagcttctgctggaggctcggacgatgagggttcaacggctgca actgacggcagtactttaagaacttcgccagccgaacaagggggaagtggtggcagtaaa ggaagtgaaagcggtggaagcgattcaggtggcagtgcagttgacagcatcactggcgaa cacaacgtttccggaagaagttccgcctacggtgacaacgctcccgaaagtataccttca atgaatatcggtcagccttcacgttctgaaaatagttccgtcggtgctgcgactgctttc agcgctacggaacaggaacaagaacaggaacaggagcaggaacaagtattggaacaagat acggataatgtcggtgaaaatacaatgaatcttcacgatatcagacttttgctacttgat aaattgatgcaatttattcccgatttgacaaatgtctctggcgtgttagcaattccattt atgcaggtaattttgatgttaacttccgatctcgatggtatggacgaaagagataaaacg tgcgttgaacgactattgcaaattttggtgaaagaattggaaatggaaaatcccgataca agtgacatttgccaaagaagcaataagagagaagttcatcttgtaattatgcgactgctg agtgttttaatgtcaagatcaaaaggcagtacaaagagtcaagttgaaaatccaaatttt gtatcacaaacaactgcggctattttgagtaataatggagtcatcgattattgcttgaat cttctgaaagcactacttgactattggaaaaacacctcgaacgaagaagctggaaacgtg attggtggtcagttactgaaggaacatctcattgcatctccacccgatatgtcgccattc ttcttgagacagtacgttaaaggtcatgcgagcgatgttttcgaaccgtatccacaattg ttgactgaaatggcgctgaaattaccgtaccaagtgcacaagtatgcagaaaattcagtc gtacaaccagaattcgatcagcaagcatggttctactatctttgcgagtacatgatgtcg tatcaaacaccattcgtgagacgacaagttcgtaaattattgcttttcatttgtggaaac aaggataaatatcgacaattgagggacttgcactcactcgtttctcatgtccagtcagta caacaatgttgtaatacgggcggttacgatccacttaattctcatcctctggcaattaat ttgccttacgattcgctcgtcgaactgatagagcatctcaagagttgcgtcgaagttgcc accagtagaactggcaattggcagagattttgttcaaaacacaacacagttctgtcatat ttattcactatctcgacacttttagacgaaggcgtcagtcccacggttcttcaactactg caatgcgcaatttgttccagtaaattcaaagaagtcaaaagcaaggacacaaagtcaacg acatcatcgacaaaagaaagaagagatcgagaaaaatctgaagattcggatacagaggca aaattcgaggaagcacaatgtgtatttctggttaaacaaattcaacaacaagtttcaccg gccttgcttacgaaatttattcagacattccttctcgaggcgaataatacaaatgtgcgc tggcaagcacattcactaatactcgccatctataaaaattgtggtccatcaaatcaggaa attcttctcgatctcctctggcgattgtggcccctacttccaatgtacggccgcaaagcc gcacaatttgtcgatctactcggttatttctcattaaaaacaccacacaccggcaataaa atgcacgtctacatggagcaagcagtcgccgtattacacgccgaaaacgaattactatcc cgtcatccaaatgcgaatctctacgcaaatcttgcccaattcgtcgaactcgatggctat tacctggagagtgaaccatgtctcgtttgtaacaatcccgaggtcccgatgtcgaccatc aaactctcttcgattaaagtagattcaaagtttacgacaactactcaaatagttaaatta gtgggtagtcacaccataagtcgtatcaccttacgaattggagacttaaagagaactaaa atggtgagaacaatcaatgtcttttataacaatcgatcagtacaggcagttgtggaattg aagaataaacccgccatgtggcacaaggcgaagaaaataactctcgctcagggacagacg gaaattaagatcgaattccccttgcccatagtggcttgtaatttgatgatcgagtacgct gatttttacgaaaatatacaagcatcgtcggagacgttgcaatgtccgagatgttcggcg agcgtaccggcgaatccgggtgtttgtgcgaattgtggcgagaatgtatttcagtgccac aagtgtcgggctattaactatgacgagaaggatccattcttgtgtcacgcttgtggtttt tgtaagtacgcgaaatttgattatacactcacgggacgtccttgctgtgctgtggatccg atcgagagtgacgaggatcgaaagaagacggtcgcgacgatcaacacattgctcgagaag gcggatcgagtttataagagtttgatttcgaataaaccgacactggagatgttgctggtg aagatatcggagcatcgatcggataggagtttggaagatgggggtgttgttgccggggga agtacgcaagtaaatcgagcgatacaacttttggcgcagaaatattgcggggagtgtaag acatctttcgaggaattgagtaaaattatacaaaaagtcctggcatgtaggagggaattg gtggcgtacgatcggaatcagagaggattggcggtgattcagcatcagcaggcgtcgacg agtgatggatcggttgagccgatagcgccgaatgcggggcgatgttacgggtgtgcgtcg gcggcgacggagcattgcttgacactgttgagagcgttggctacgaatcaggcggcgcgg gaggttttgtgtaaacatggattgatacaggagttggtggagcataatttgaggaaaggg acgatacagatgcaggaggaggtgaggcagttgctctgtttggtgacgagggataattcg gagtcgacgaaggagctttgtgcgcttttgacgaatcgggtgacgatgacgctgaagggg aggattgcgacgcatgatctgtcgatggcggtgaggcatgagatgtcacttttggcggcg ttggtgcagaaggaggattcgtgctgggagcagaaattgagatgtgtgatgcaattgttt ctgttggcttgtaaggattcgaagagtccggtggtgatggactcggtgattctgccgtgt atgaagattctgcagagtgtgatcaagccggagcagccggtgtcgaagaagaataaggat aagagtacggagtcgttggcgacgatacaaccgccggcggggattagcattgatatcgga aagtggttgagcggggattcgatgtacacttatgcgaattggttggaacgagtgccgacg aggaagagcgaagcgggaccgagcaagcagctgacgaaggaggaagctagaattgtttat ttgatggagaaatacggtcatcggtggcataatcgctgtcatcatttgagggacatgaag tctttgaaattagtcgatggcgcttggttgaaggaggttttattcaatccgagttcgaga ctagcgcgtcaagtggcttgtacgatgattgaaagtctctgccaggggatggagaggaag aaagaattgctggtcctcctgacgaattatctcgaggaggttcacatagccggggaaagc agcgctgaattcttgtccctttatcagagtctaatcagacagtcgccttggaagcagttc ttggccgtgaaaggcgttctcacactcctcgccgagttgttgacccgcgaaatcgaggat cttcaccgcctcgaagaaacgactttaactagcgatctcgcccagggttattctttgaaa atgctcaccgaactcttggcaaccttcctcgagcaggagaatatcaagcaacactacaaa ggaagactcgtaggggccgttctcaatggttacctctcgctaaggagactcgtcgttcag aggacgagactgatcgacgacacgcaggagaagcttttggaacttttggaggagatgaca accggaacagaagaggagacaaaggcctttatggccgtgtgcgtcgaaacgatacaaaag tacagtccccaggacgtaagaactccggtatttatattcgaacgcctctgctcgataatc tatcccgaagagaatgacgtcggtgaatttttcctcactttggaaaaggattcccagcag gaagattttctccagggaagaatgctgggcaatccctacagtagtttggaacccggtctc ggaccactgatgagagacgtgaagaataaaatctgtcaggattgtgaattggtggcattg ctcgaggacgacaatggaatggaactacttgtaaataataaaataataagtctcgattta ccagtgaaggaggtgtataaaaaaatctgggtcgtcgagggtggtgagtgcgatgcaatg cgagttgtttatcgaatgcggggacttcttggcgatgcgacggaggaatttgtcgagaca ttgaatgcgaatagcgagcaggaggtgaataatgaggaggtgtacaaaatggcgaatgtt ctcgctgattgcggtggtttggaggtgatgttgaatcgattggcggctattcaggacgtt agtcgagcgagaccgttgctgcaggttttgttgaaattattccgattgtcagtgaaggtg aagaagaatcaggaggttctgagtcgaccggaattaaaggcagtgtctgttttactcgac gttttgcaaagatgtctagagacggagtctgatagttcacaggcgaaaataacggagcaa ttactcgatattatggagacaattctagaaaatgcggccgcacaaccattgagttccttt gaggaattctcaaagacactcggcggtgcggatcatataaaaacacttctctcctgcacc caatcgtcagcggtgagacaatgcaataacgttctgatgcacctggctagagtcctagcc gcactcacttacggcaacgaggagaaaatggccctactttgcgattatttcaaaccagtt ctaaacttttacaaattcgattttgaacacacaaccgaggatgatcagaaattggaacta ttttgtattctaacgcaaggcattgagagaaatgcgattggaaacacactcaaggatcat attatcaatatgggaattgttaaggatgctttcgagtacataacgatgcatgcgccttgc gtgaagccaacattattgagaacggacagtgatgaattgaaggactttatatcgaaaccg tcgttgaagtatatattgagatttctcactggacttgcgacggaacatgaaccgatacaa ttgtcagtgtcgccggcgattataagcattattcatcgattggagcaggtatcgtctgat gaacatgtgggatcattggcggagaatttactcgaggcattgtgtacgaataaaaaagtt tcggaattaattgaagaggcgagacaacatacgaggagtgagaagaagagactcgcgatg gcaatgagagagaggcaattgggtgctttgggaatgagtaccaatgataagggtcaagtc actgcgagtaagacaattttacagcaaatggaggatctgggcgatgagacgggtctcatt tgtgttatttgcagagagggatataaattcaagcccaatatggttctgggcatatacaca tttacgaaacgatgtaacgtggaggagtttgagacgaaacagaggaaaacaatcggctac acgacggtgacacatttcaatgtggtgcacgtggattgtcacatgtcggctgttcgatta gcaagagcgagagacgaatgggagagtgcagcgctgcagaatgcgaatacaaaatgcaat ggtctactaccactttggggaccacaagttcctgaatcggcattcgccagttgtttagcg agacacaatacatatttgcaagagtgcacgggacatcgcgacatttcttattcgtcgaca attcacgatcttaaattactcctcttgcgattcgcgcaggaaaaaactttccatgaggat acgggtggtggtggaccacagtcaaacatgcacataataccttatttaattcacatggct ctctatgtgatcaacacaacacgatcggcagcgagagaggagaaagcacacatgtcgtat ttacattctactgccagctcctcttggcttgacagttgttacgaggctgatggtccattt tatcagtgcacactgtcactccttgtaatgccaccctcacaatggaataaattcagaatt actcatttgaggagactcattattctcgctcaacaaagatacacttctccttcgttgtca acgaaaaatctcaccgatgttaccgtcaaagattattcagtatacaagagtgtccttatc ttctttggtcttgtcgattgcatatacaatacattttttaagaaagttgttgtcacttca gacgaacaatggccgtcaattttagctgaatatattcgacacaatgatgaagctttattg aaagcttcggagcgtgttttggcaacctatcgagatgaattgttaccttgtgaatcattc gaagaatattgtgatgttgtcggtttaatcgaagatgtgacagacatttcgtcgtatata agcaaagttctgaaagatctcgcttag

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