Leptospira interrogans serovar Copenhageni: LIC_11726
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Entry
LIC_11726 CDS
T00166
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
lic
Leptospira interrogans serovar Copenhageni
Pathway
lic00290
Valine, leucine and isoleucine biosynthesis
lic00620
Pyruvate metabolism
lic01100
Metabolic pathways
lic01110
Biosynthesis of secondary metabolites
lic01210
2-Oxocarboxylic acid metabolism
lic01230
Biosynthesis of amino acids
Module
lic_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
lic00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
LIC_11726 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
LIC_11726 (leuA)
Enzymes [BR:
lic01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
LIC_11726 (leuA)
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
Motif
Other DBs
NCBI-ProteinID:
AAS70315
UniProt:
Q72RL9
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All DBs
Position
I:2100758..2102344
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AA seq
528 aa
AA seq
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MSVRLIDCLKNKTQKTGSRIFCEKDMAMDLKDYVRIFDTTLRDGEQCPGAAMTENEKLEI
ASQLATMKVDIIEAGFPVSSPVQFQAVERIARETEGPMIAALARAMKADIEAASKALQPA
KKRRIHTFIASSPIHMKYKLGKEPKEVLKMAVEAVTLCRQFVDDVEFSPEDATRSEPEFL
RELCEAVIAAGATTINIPDTVGYTTPAEYGGLFKFLLSNVRGAEKIIFSAHCHNDLGLAT
ANSLAAVQNGARQIECTINGIGERAGNTAMEEVVMAMRTRKDTFGIQTQIKTEEIARASY
LVKTITGMLVQPNKAIVGANAFAHESGIHQDGVIKHRETYEIMKPETVGLSSNRMVLGRH
SGRAGFKDRIVKLGFSPQVEELEAAYQRFLEIADRKKEIYDEDIRALFSEEARKSTGDRF
QLEGFTVSTGTKSTPTAGVRILIDGHVREESATGDGPVDAIYKAIQKTTGMDPEVSRLVI
SPVTEGQDAMAEASVTLEYKGDRVVGKGSSTDIIEACSRAYISALNRL
NT seq
1587 nt
NT seq
+upstream
nt +downstream
nt
atgagtgttcgtttaattgattgtctaaagaataaaacccaaaaaactggaagtagaatt
ttttgcgagaaagatatggcaatggatctaaaagactacgttcgtatatttgatacaact
ctcagagacggagaacaatgtcccggggctgcgatgaccgaaaacgaaaagttggaaatt
gcttctcaactcgcaacgatgaaggtagatattattgaagccggatttccagtttcttcc
cccgttcaatttcaagcagtggaaagaatcgcaagagaaaccgaagggcccatgatcgcg
gcactcgctagggcaatgaaggcggatattgaagccgcatctaaagcgcttcagcctgcg
aaaaaaagaaggattcatactttcattgcatcttctccgattcacatgaaatataaactc
ggaaaagaaccgaaagaagttttaaagatggctgtagaagcggtgacactttgcaggcaa
tttgtggacgacgtggaattttcacccgaagacgcaactaggagcgaacctgaattttta
agagaactttgtgaagcggtaattgcagcaggagctactacgatcaacattcctgacact
gtaggttataccactcctgcagaatacggtggtctttttaaatttctgctcagcaacgta
agaggagccgaaaaaattatcttttctgctcattgtcataacgatttaggacttgctacc
gcaaattccttggctgcggttcaaaacggagctagacaaattgaatgtacgattaacggt
atcggagaaagagccggtaatacagcaatggaagaagtagttatggcaatgcgtactaga
aaagatacgttcggaattcaaactcaaattaaaaccgaagaaattgcccgcgcctcttat
cttgtaaaaacgattaccggaatgctcgttcaaccgaacaaagcaatcgtaggagcaaac
gcatttgcacatgaatctggaattcatcaagacggagttatcaaacatagagaaacctac
gagattatgaaaccggaaaccgtcggtctttcttccaatagaatggttttgggaagacat
agtggtcgcgccggttttaaagatagaattgttaaactgggtttttctcctcaagtagaa
gaattggaagccgcttatcaaaggtttttagaaattgcggacagaaaaaaagaaatctat
gatgaagacattcgagcgcttttctccgaagaagctagaaaatcaaccggagatcgtttt
caattagaaggttttacggtttccaccggaaccaaaagtactcccactgcgggtgttaga
attttaattgatggtcatgtaagagaagagtctgcaaccggagacggcccggtagacgca
atctacaaagcgattcaaaaaacaaccggaatggatccggaagtctccagacttgtaatt
tctccggttaccgaaggacaagatgcaatggctgaagcctccgtgactttagaatataaa
ggagaccgtgtcgtgggaaaaggaagttctacagatattatcgaagcctgttcaagggct
tatatttccgcactcaatcgactttga
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