Leishmania infantum: LINJ_21_1670
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Entry
LINJ_21_1670 CDS
T01112
Name
(RefSeq) putative 2-oxoisovalerate dehydrogenase alpha subunit
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
lif
Leishmania infantum
Pathway
lif00280
Valine, leucine and isoleucine degradation
lif00640
Propanoate metabolism
lif00785
Lipoic acid metabolism
lif01100
Metabolic pathways
lif01110
Biosynthesis of secondary metabolites
lif01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
lif00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
LINJ_21_1670
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
LINJ_21_1670
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
LINJ_21_1670
Enzymes [BR:
lif01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
LINJ_21_1670
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Ortholog
Paralog
GFIT
Motif
Pfam:
E1_dh
DUF8389
DUF4440
Motif
Other DBs
NCBI-GeneID:
5068849
NCBI-ProteinID:
XP_001465431
UniProt:
A4HZE0
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All DBs
Position
21:complement(577832..579271)
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AA seq
479 aa
AA seq
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MFHISRAVRCNALATAIAGRTSLSDAIRQVQKVWNLDFKDGPVTTSTLTFNDEPDPAAPI
FHVLDLQGGVFVEEKADSGAAAATPSTVNEAGKTELQSAELGQVFRYHAKDETSVITREV
AERMMSAMLTHNTIDKIMLEAQRQGRISFYMTMFGEEAAVIGAAAGLASNDELFAQYREA
GILTYRGYTIPEFIAQCMGNCECDLKGRQMPIHYGSKRLNAQMVSSPLATQIPHGAGAGY
AFRLENQALERRLPTGTLLSTIPEARICATFFGEGAASEGDFHAGLNFASTVGSHTLFFV
RNNGYAISTPTHSQYMGDGILSRAVGYGMPAARVDGLDALAVYHTVRKAREMILNNHRPV
LVEALTYRLSHHSTSDDSTAYRSRDEIEHFAETFSPIERFERFMAERGWWTPEQSTEVVE
RTRREVLSELRRQEKLPAWPVSTLCDDVFEHLTPELERQRAQLVEHYQAHRSIYDQEKL
NT seq
1440 nt
NT seq
+upstream
nt +downstream
nt
atgttccacatctctcgtgcagtgcgctgcaacgcactcgccaccgccatcgctggccgt
acctcgctaagtgatgcgatacgccaggtgcagaaggtgtggaacctcgacttcaaggat
ggaccggtgaccacgagcacgctgacgttcaatgacgagcctgacccggctgcgccgatc
ttccatgtgctcgatttgcaaggcggcgtctttgtggaggaaaaggcagacagcggagct
gctgcagcaacgccttcaaccgtcaatgaggctggcaaaactgagctgcagagcgccgag
cttgggcaggtatttcgctaccatgcaaaggatgagacgagcgtcatcactcgcgaggtg
gcggagcgcatgatgtcggcgatgctgacgcacaacaccatagacaagataatgctagag
gcgcagcggcaaggccgcatctccttctacatgacgatgtttggcgaggaggctgccgtg
atcggcgcggcggctgggctggccagcaacgacgagctcttcgcgcaatacagagaggcg
ggtattctgacgtaccgcggctacactatacccgagtttatcgcgcagtgcatgggcaac
tgtgagtgcgatttgaagggccgtcagatgcctatccactacggcagcaagcgtctgaat
gcgcagatggtcagctccccgctcgccacgcagatccctcacggcgccggcgccggctac
gcgtttcggctagaaaaccaggcgctggagaggaggctgccgactggcacgctgctgtcg
acgattccggaggcgcgcatctgtgccaccttcttcggcgagggagccgcgagcgagggc
gacttccacgctgggctgaacttcgctagcaccgtcggctcgcacaccctcttctttgtg
cgcaacaatggttacgccatctcgaccccgacccacagccagtacatgggcgacggcatc
ttgagccgtgcggtaggctacggcatgccggccgccagagtcgacggcctcgacgcgctg
gcggtttaccataccgtgcgcaaggcacgtgaaatgatcctgaacaaccaccggcccgtc
ctggtggaggcactgacgtaccgcctctcgcaccactcaacctcggacgacagtaccgcg
taccgctcgcgggacgagatcgagcacttcgcagagacctttagccccatcgagcgcttt
gagcgcttcatggcagagcgtggctggtggacgcccgagcagtcgacggaggttgtcgag
aggacccgcagagaggtgcttagcgagctgcgtcggcaggagaagctgcctgcatggcca
gtatcgaccctgtgcgatgacgtctttgagcacctgacgccagagctggagcggcagagg
gcgcagctggtggagcactaccaggcgcaccggtctatctacgatcaggagaagctttag
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