Leptospira interrogans serovar Lai 56601: LA_2350
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Entry
LA_2350 CDS
T00098
Symbol
leuA
Name
(GenBank) isopropylmalate/homocitrate/citramalate synthase
KO
K09011
(R)-citramalate synthase [EC:
2.3.3.21
]
Organism
lil
Leptospira interrogans serovar Lai 56601
Pathway
lil00290
Valine, leucine and isoleucine biosynthesis
lil00660
C5-Branched dibasic acid metabolism
lil01100
Metabolic pathways
lil01210
2-Oxocarboxylic acid metabolism
lil01230
Biosynthesis of amino acids
Module
lil_M00535
Isoleucine biosynthesis, pyruvate => 2-oxobutanoate
Brite
KEGG Orthology (KO) [BR:
lil00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
LA_2350 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
LA_2350 (leuA)
Enzymes [BR:
lil01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.21 (R)-citramalate synthase
LA_2350 (leuA)
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Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
Motif
Other DBs
NCBI-ProteinID:
AAN49549
UniProt:
Q8F3Q1
Structure
PDB
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Position
I:complement(2325127..2326677)
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AA seq
516 aa
AA seq
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MTKVETRLEILDVTLRDGEQTRGVSFSTSEKLNIAKFLLQKLNVDRVEIASARVSKGELE
TVQKIMEWAATEQLTERIEILGFVDGNKTVDWIKDSGAKVLNLLTKGSLHHLEKQLGKTP
KEFFTDVSFVIEYAIKSGLKINVYLEDWSNGFRNSPDYVKSLVEHLSKEHIERIFLPDTL
GVLSPEETFQGVDSLIQKYPDIHFEFHGHNDYDLSVANSLQAIRAGVKGLHASINGLGER
AGNTPLEALVTTIHDKSNSKTNINEIAITEASRLVEVFSGKRISANRPIVGEDVFTQTAG
VHADGDKKGNLYANPILPERFGRKRSYALGKLAGKASISENVKQLGMVLSEVVLQKVLER
VIELGDQNKLVTPEDLPFIIADVSGRTGEKVLTIKSCNIHSGIGIRPHAQIELEYQGKIH
KEISEGDGGYDAFMNALTKITNRLGISIPKLIDYEVRIPPGGKTDALVETRITWNKSLDL
EEDQTFKTMGVHPDQTVAAVHATEKMLNQILQPWQI
NT seq
1551 nt
NT seq
+upstream
nt +downstream
nt
atgacaaaagtagaaactcgattggaaattttagacgtaactttgagagacggggagcag
accagaggggtcagtttttccacttccgaaaaactaaatatcgcaaaatttctattacaa
aaactaaatgtagatcgggtagagattgcgtctgcaagagtttctaaaggggaattggaa
acggtccaaaaaatcatggaatgggctgcaacagaacagcttacggaaagaatcgaaatc
ttaggttttgtagacgggaataaaaccgtagattggatcaaagatagtggggctaaggtt
ttaaatcttttgactaagggatcgcttcatcatttagaaaaacaattaggcaaaactccg
aaagaattctttacagacgtttcttttgtaatagaatacgcgatcaaaagcggacttaaa
ataaacgtatatttagaagattggtccaacggtttcagaaacagtccagattacgtcaaa
tcgctcgtagaacatctaagtaaagaacatatagaaagaatttttcttccagacacgtta
ggcgttctttcgccagaagagacgtttcaaggagtggattcactcattcaaaaatacccg
gatattcattttgaatttcacggacataacgactacgatctttccgtggcaaatagtctt
caagcgattcgtgccggagtcaaaggtcttcacgcttctataaatggtctcggagaaaga
gccggaaatactccgttggaagcactcgtaaccacgattcatgataagtctaactctaaa
acgaacataaacgaaattgcaattacggaagcaagccgtcttgtagaagtattcagcgga
aaaagaatttctgcaaatagaccgatcgtaggagaagacgtgtttactcagaccgcggga
gtacacgcagacggagacaaaaaaggaaatttatacgcaaatcctattttaccggaaaga
tttggtaggaaaagaagttacgcgttaggcaaacttgcaggtaaggcgagtatctccgaa
aatgtaaaacaactcggaatggttttaagtgaagtggttttacaaaaggttttagaaagg
gtgatcgaattaggagatcagaataaactagtgacacctgaagatcttccatttatcatt
gcggacgtttctggaagaaccggagaaaaggtacttacaatcaaatcttgtaatattcat
tccggaattggaattcgtcctcacgcacaaattgaattggaatatcagggaaagattcat
aaggaaatttctgaaggagacggagggtatgatgcgtttatgaatgcacttactaaaatt
acgaatcgcctcggtattagtattcctaaattgatagattacgaagtaaggattcctcct
ggtggaaaaacagatgcacttgtagaaactaggatcacctggaacaagtccttagattta
gaagaggaccagactttcaaaacgatgggagttcatccggatcaaacggttgcagcggtt
catgcaactgaaaagatgctcaatcaaattctacaaccatggcaaatctaa
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