Liolophura japonica (common chiton): 135468178 Help Entry 135468178         CDS       T09976                                  Name (RefSeq) ryanodine receptor 2-like   KO K04962   ryanodine receptor 2 Organism ljp  Liolophura japonica (common chiton) Brite KEGG Orthology (KO) [BR:ljp00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:ljp04040]     135468178    04990 Domain-containing proteins not elsewhere classified [BR:ljp04990]     135468178 Ion channels [BR:ljp04040]  Voltage-gated cation channels   Ryanodine receptor    135468178 Domain-containing proteins not elsewhere classified [BR:ljp04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    135468178 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR SPRY MIR Ins145_P3_rec RR_TM4-6 RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_5 EF-hand_6 EF-hand_8 EF-hand_11 DUF819 Motif Other DBs NCBI-GeneID:  135468178 NCBI-ProteinID:  XP_064602338 LinkDB All DBs Position 6:43679..215502 Genome browser AA seq 5223 aa AA seqDB search MADSTEGGGSEQDDISFLRTDDNVCMTCVASLTRDSVERVCLAAEGFGNRMCFLENVSSK DVPPDTSVCVFVLEQALSVRALQEMVTSTSQDSTATQSGHRTLLYGHAVLLKHLHSNMYL SCLSTSSSNDKLAFDVGLQEMAHGESCWWTIHPASKQRSEGEKVRVGDDLILVSVSSERY LHIGSGASVIASFQQTLWTVAPVCSGAIRQKTLGYVFGGDVLRLFHGHMDECLAMPQAGS DNEHNAVMYETGAVCSHARSLWRMEHIRIKWAGGFIGWGHQCRIRHVTSGRYLGVVNENQ VVTVHRNRADEASTAFYLRQSKDDKKQSEGREDEGMGKADIKYGDSIAFIQHCSTGLWLS YQTFETKKRGVGKVEEKKAIMLVEGHMDDGFTLTRAQEEESRSAGVIRKCQSLFHRFNTA LDALKDEGISSNAWSRISLSEVLKCLEDLIEYFAQPGDDEEHEEKQNKLKALRNRQDLFQ EEGMIALILETIDKFSHYKSRRQFAYYAGEDAAQNWDDISSYLYLLLAAMIRGNRANCAQ FAQSYRLDWLVNRLESQQSSKGVLDVLHCVLIDSPEALNMIKEKHIVTIISLIDKHGRDP KVLDVLKSLCVGNDVAVRLNQNLICDNLLPGRDLLLQTKLVDQVTSIRPSIYVGLKAGSA MYKKWYYEVIVDHVEKTTHLPPLLRVGWANTGGFVPYPGGGEQWGANGVGGDLYSYAFDG LNLWTGGKPKQVRHASQMLQKHDIIGCCLDLALSQITFSLNGNKIRGFFKDFNVDGMFFP VISMSAKVSCRFVLGGDHGKLKYGPPEGHSPVFESLPPREKLKIEPCFHLGDVQKSIVCG PAGNLERVVFVPHPVDTAHIQLPAYIENVRDRLAENIHELWAMNKIEQSWTYGERRDDTK KTHPCLTTFERLPMSEKKYDITLAYETLRTLLALGYHITIDAKKQSSRLKTLKLGNPYLQ SNGYKPTPLDLSGVTLNEKMQELVDLLAENTHNVWAKDRIKQGWTYGHTESQANKRSPHL VPYSKVDATIKKANRDTATETVKTLLAYGYNLEPPTNETGESAVSRDAADVKNLSQTFRA EQTYAVTSGKWYYEFEVLTPGSMKIGWATVSCDSNQELGLDGTSYCFDGFTARKWHQGPD PYGKMWQVGDVIGCMLDLQDRTISFSLNGELMMDALGQEIAFRGVDTSDGYVPAMTLGAL QQGKLNFGQDVNSLKHFTCCGLQEGYEPFCVNMTRHLPMWYSKDLPLYSPILSNHQRIQV SRIPGGSNVTPCLKVSSKTFGTLEKVRLEFLRLSLPVKCHDYFSPRGDKGTPSSATMFER RMNFENARRHGYDSFDGMVNGDTYSDANISEASFEESTRAYPDDEDYSPRGMANGGPDLT LRKTIHRGYTEDESIGAQDRRKTFRQTSKAGQAHHSLDDRGVQQLLPGQIKPAASESHLD HEGKNTLSVPGRKERSGSKVSLSGLMDKMASTVKGGSSEMDKTGKRGKSPFTAIFRRSKS RDPSPSGRTPKTEKRGSFRVPRDQSGAGRSQTLPPKIVSSADGDVGPSLEAPKSFIPYEF QDAIGGRQMPRNFSQNSMDDLDLQSDEELNELNALAQDVHEYHYAVRIFPGQDPSQVHVG WVTSSFHGLSKTFDLKKIRHVIVSTLDMDYAIKQSVSRKDCYMVSAGDLQQRYGGAQDNM SSKRASPGLLIGCTIDAASGLLSFSVNGKEVANKFQVEPGVSLFPAVICEPTIKEMFQFE LGRTKHTLPLSAAVFRGPKSIVPSCPTRLDVQVMKESHWGRVPDSTVRVHILKLSDIRGW SAFCEEPVSMLAVHIPEENRSLDILELKEYTDLLTFHARTLDLYQAVCSHGNHKVANVLT SHVDERQLMHCIRSEYLAGPIRHGFHNLLISLHLESHAHSRLLTQNEFIVPLTVQTRSLS LFRRPSPTSDTYKIKHSIPVMEKSVSIRPELSIGKEAEHKAKVGFKDQLAPVFPVAQLKR HVMKSLTEAVSKGAAHIRDPIGGSNANLFVPLLKVCDNLLVMGLLDDDDLYHLLCLIDPT SFDEKYDRRQPKTGLLHMVLAEDVKLELCHILQHICDCQLRHRVESIVAFADDFVGESQN DQLRRYIEIKQADLPSAITAKKTREFRCPPHAQMKALLAFKVEEEEEEKQSPCREDMKES LRCFHSDLLRHCTIPTIQEPEKTQDVVAEEKTTSVSEKLLQLVWKVKEDDKNDYLDDVEK PDSLQTLIGRTMVRWAEESFIQNQNLVREMFSLLHRQYDGVGELLRAMDKAYVISSASKE DINHLLKALGHIRSLLSVQAGPDEEEMMKNSLKELMDNKVFFQHPDLMRALCVHETVMQL MVNTLNKAQQQQSAAIGGATELSTSQNKPTVVTAASDSLIEPSKDAAAEMVVMCCRFLCY FCRTSRQNQRAMFDHLSYLLDNSSMLLARPSLRGSCPLDVAYSSLMDNNELALALRESHL EKIAMYLSRCGIQSNAELTEKGYPDIGWDPVEGERYLDFFRFCVWVNGESVEENANLVVR LLIRRPECLGPALRGEGGGLLKAMRDGIKMSEQITAARDSNSSQFLTAVNDDDDTGGQYL FQSKYDFSLLPPEDDEDYIDMGGAILNFYSSLVDLLGRCAPDAETIKAGRSDSLRARAIL RSLVSMEDLEGVLGLQFILPVGPPAPPGGASTSSNDDGGGALGGGGLPPGLLPIHKASIV LFLERVYGIPDQTTFFRLLEDGFLTDLRAATTLDTAVASESDMALALNRYLCASVLPLLT THAHFFNDADHVSSLIDSTLNTVYRLSKCRSLTKGQRDIVSDYLVAFTNQLRPPSMTRLL RKLAVDVPALSENAVVPLRLLTHYFERCGRYYSSGGWGTLGSASEEEKRLTMMLFSGIFD SLAQRAYDPELFSRALPCLSAIGCALSPDYSLSHQDENWYRQMSVDADGGYNPMPVNTSR VALAGALDLVVNKFAEHYHDCWALKKIDQGWVYSSVYDDDKKHHPLLKPYHLLSEKDKMK YTEPVRESLKAMLTWGWTLDQDQARFTSNRDSMKRRGSKAQFEHGYSPRPYDLRNMTLTR ETQTLAERIAENSHDSWAKKKKDELDAIGGGVHPQLVPYDILTDKEKRKDRSQAQELLKF LQFMGYRIHSTDMELGGMRRDSHSRQSKESEADSGVGVSATEKRFAYSLLEKLLEYLDKA SQNMKQNKPSSRYSRRGSYTTATEDVKFFGKVVLPFVERYFHAHRLYFIASPSSPQSSSG GMASAKEKEMTASLFCKLAQTLRSKITAFGHDVNISVRCLQVLVQAVDARSVVKNSPEIV RASLLPFFNNAADDLNQVVDNLSRGRFSHIKGTITKGATSLNMVHMVLLPVLSSMFDHLG NQHYGSDLIVGEIQLACYRILNSLYLLGTSSSSVVQRETFQAELARHRPALGECVGSFAT CFPVAFLEPHLNKYNKHSMLFGLEGKIADHSLEAQVVMDQLVENLPNLEKIVAEIEELAE SGGKYQEAPHVIEVTLPMLCSYLPVWWSQGPDKVPSERGHHTTSVTAQLMNSVLGNVLKL ILNNIASENAPWMKRIATRTQPIIGNSTPDMVRDHFLPVAQKLRDNAKTVEQEERRLNQD RKIISEVADQEARVQERFSIFVRDIYAFYPLLIKYVDLHRSHWLKHPTAEAEELFSCVAN IFLLWSKSVIFRREEQNFVTQNEIDNLALIMPSQAKRLSPSKVDQKGGQKGSATDKMRKK EKKKLESHNSLNVACLKRLLPIGLTVFGGKEQELVQQAKQKLFQKESDGDVEEFLLLSLE QGEDASEKDEKVQWQKLLYKKIGTTKLEGISQLNQAKIVEKILSMAKVLHGLHLVEHPPP SLKNAWKKVISTQRKRAVMACFRMIPLHGLPRHRAINLFLRSYKQQWLNIDYMEEEKNTL IEDITHNKEEEEMEAVEKKELEEEITPDSLTQLITALSRAATKEQQSSIPEDFLYMSYAD IMSKSCSGEDEDDEEEGGEDAGSSFQEQEMEKQKLLFEQSRLADRGAAEMVLLYISASRG VSGEMTSSTIELGISLLRGGNQDVQKSMLKHLRDKKDVGFFTSLAGLMQQCSVLDLDAFE RCNKAEGLGMSSDAGAGEKNLHDAEDTCKLFRFLQLLCEGHNLEFQNYLRTQAGNTTTVN IIICTVDYLLRLQESIMDFYWHYSGKDIIDSAGKDNFCRAIKVATQVFRTLTEYIQGPCS LNQLALAHSRLWDAVGGFLYIFAHMQNKLSKDADQLELLREFMKLQKEMMIMLLSMLEGN VMNGPIGKQMVDTLVESSANVEMILKFFDIFLKMKDLTTSEAFLEFDTNKDGWISCKEFR RAMEAQKVYSDEEIDYVMMCVDANQDGKVDFQEFTDRFHNPAKDIGFTMSVLLTNLSEHM TNDPRLDKILEKAKPVLDYFNMYLGRIEILGSSNRIERVYFEIKQSHIDQWEKPQIKESK RSFLHSVVNEGGDKEKLESFVNFCEDTIFEMQHATSISAEEQRLAALKAGQGEDVGVLEP VRMMFRFIRDGLGTILSLFTWSNIKTGYKTFKSMTYFQLLVAFLKMNIRLTLLLLTFLFH VAWTLCKFLANMMMGEKPSDDPVQDKKGPPALTAGPMVLHNTGHPGGGYGGGLPFYEPEI HVQPSSAFGIIITNKEETTQSDESAPPPGDMGSGLQPTTASKDAKPASAKAPSVKQTQWS SQSGEATSDEEEPLLREEETPETSRPPPRKPYSDVPVGFIGEWAFVPGSDPSSSTSAQEE DVLVEPRSFDYGKYILSLFARNFYNFKYLGLAISFLINIILLFYKVSKVTGEGVEGGAGN DTSDDDVEEFVVIEEDVSYLEPIMRTLAFVHSLVSLSMLVAYYCLKVPLVIFKREKEIAR MLEFEGLWIAEQPSEDDIKCHWDKLVISTVSFPQSYWDKFVKKKVRNKYSEQYDYESISN LLGMDKGDSITISTEEQQQSGILPSFLCNVDWQYQIWKWGVIFTDNSFLYIMGYFIFSVC GNFNYFFFAAHLLDVAIGFKTLRTILQSVTHNGKQLVLTVMLTSVVVYLYTVVAFNFFRK FYVKDEDGNVDYKCHDMCLFVCYSVFVYHLHTGVRAGGGIGDEIEPADGDAYEVPRILFD ITFFFFVIVILLAIIQGLIIDAFGELRDQLEQVKEDMESKCFICGIGKEYFDKVPHGFET HVQNEHNFANYMFFLMHLINKPDTEYTGQESYVWELYQNRSWDFFPVGDCFRKQYDDDAA KDH NT seq 15672 nt NT seq  +upstreamnt  +downstreamnt atggcggattctacagaaggagggggctccgaacaagatgatatttcattcctacggacg gatgacaatgtgtgtatgacatgtgtggcctccctaactcgggacagtgtagagcgcgtg tgtctggcagcagagggcttcggaaaccgcatgtgctttctggagaatgtcagctcaaag gatgttccaccagatacatcagtatgtgtctttgtactggagcaagccctttctgtcaga gcactacaagagatggtcacttctacatcccaagattccaccgccactcagtctggacac aggacattattatatggccatgctgtactacttaaacacctgcacagtaacatgtatttg tcctgtctgtccacaagctcctccaatgacaaactggcctttgatgtgggtcttcaggag atggctcatggggagtcatgctggtggacaattcacccagcctccaagcagagatcagag ggtgaaaaggttagggtcggggatgacctcatccttgtcagtgtgtcctccgagaggtac ctgcacataggcagtggggccagtgtgatcgcatcctttcagcagaccttgtggactgtt gctcctgtgtgctctggggcaatacgacagaagactttaggttatgtatttggtggagat gttttgagactgttccatggtcacatggatgaatgtctggccatgccacaagctggcagt gataatgaacacaatgctgtaatgtatgagacaggagctgtatgcagtcatgccaggtca ttgtggaggatggagcacatcagaatcaaatgggccggtgggttcattggatggggacat cagtgtagaatacgacatgtcacctcgggcaggtacctgggagtcgtcaacgaaaaccaa gtggtcactgtacatagaaacagagctgatgaagccagcacggccttctatcttcgtcag tccaaagatgacaaaaagcagagtgaaggacgtgaggatgagggaatgggaaaggctgat atcaaatacggtgactccattgccttcatccagcactgttctacaggactctggctgtcc taccagacgtttgagacaaagaaaaggggtgttggcaaggttgaggagaagaaggccatc atgctggtagaaggccacatggacgatggtttcacattgaccagggcacaggaagaggag tcgcgatcagccggggtcattcgcaaatgccagtctttgtttcacaggttcaacacagct cttgatgcactcaaggatgaagggattagcagtaatgcctggtcgaggatcagcttgtca gaggttctcaaatgcctggaagatttaattgagtactttgctcaacctggagatgatgaa gaacatgaagaaaaacaaaacaaactgaaggctttaagaaacagacaagatttgtttcaa gaagagggtatgattgccttgatattggagaccattgacaagttcagccattacaaaagt cggcgtcagtttgcatattacgcgggagaggacgctgctcagaactgggatgacatctcc agttatctctatttgctgctggctgcaatgattcgtggtaaccgtgctaactgtgctcag tttgctcaatcttaccgtctggattggctggtgaatcggctggagagtcagcagtcttct aaaggtgtgctggatgtgttacactgtgtgctgatcgattctccagaagctctgaacatg attaaggagaaacatattgtcaccattatatcgctgattgacaaacatggcagggatcct aaggtgcttgacgtgctcaaatccctgtgtgtggggaacgacgtagctgtgcgactcaat caaaaccttatctgtgataacctccttcctggccgtgacctcctgctgcagactaaactg gttgaccaggtcaccagcatcagacccagtatatacgtaggcctgaaagctggctcagct atgtacaagaagtggtactacgaggtcatcgtggaccatgtggagaagacgacacactta cctcccttgttgcgtgttggctgggctaatacaggtggctttgtgccgtaccctggtgga ggggagcagtggggggctaatggtgttggtggagacctatactcttacgcctttgatggc ctcaacctgtggacaggtggtaagcccaaacaggtgcgacatgccagccagatgcttcag aaacatgacatcattggctgttgtctggatttggccctatctcagatcaccttcagtctg aatggcaacaagatcaggggcttcttcaaggacttcaatgtggatggcatgttcttccct gtcatcagcatgtctgccaaagtcagctgtcgctttgtcttgggtggagaccatggaaag ctgaagtacggcccccctgagggtcactctcccgtctttgagagtctgcccccgagggag aagctgaagatagagccgtgttttcacctgggtgatgtacagaagagcattgtctgtggt ccagcgggaaatctggagcgcgtggtgtttgtccctcatcccgtggacacagcacatatc cagttgccggcgtacattgagaatgttcgggacagattggctgaaaatatccacgagctc tgggcaatgaacaaaatagagcaatcctggacgtatggggagaggagggatgacacgaaa aagacacacccttgtctcaccacatttgagaggctacctatgtctgagaagaaatatgac attaccctggcttatgaaactctgaggaccctcttggctctagggtaccacataacaatt gatgccaagaagcagtcaagcagattaaagacactgaaactggggaatccttacctgcag tctaatggctacaaacccacccccttagacctgtcaggggtcacactaaatgagaagatg caggaactggtggatctcctggctgagaacacacacaatgtctgggctaaggaccgcatt aaacagggctggacctatggtcacacagagagccaagccaataaaagaagcccacatttg gtgccatacagtaaggttgatgccaccatcaagaaagccaacagagacacggccacagaa actgtcaagacccttctggcctatggttacaatctggaaccaccgaccaatgagactgga gaaagcgctgtgtctagagatgctgctgatgtaaagaacctgtcccagacattcagggca gagcagacatatgctgttacatcaggcaaatggtactacgagtttgaggtgcttacacca ggctccatgaagattggctgggccactgtatcatgtgactcaaaccaggagctgggattg gatgggacctcctactgctttgatggcttcacggcccgtaaatggcaccaaggccccgac ccatatggtaagatgtggcaggtgggagatgtgattggctgtatgctggacctgcaggac aggactatctccttttccttgaatggagagctcatgatggatgccttgggtcaggaaatt gcttttcgaggggtggacaccagtgatggttatgttccagcaatgacacttggagctctg cagcagggcaaactcaattttggacaggatgtcaactcgctgaagcacttcacatgttgt ggcctacaggaaggttatgaaccattctgtgttaacatgacccgccacttgcccatgtgg tactctaaggacctgcccctgtactccccgattctgtccaaccaccaaagaatacaggtg tccaggatccctggggggagcaatgttaccccatgcctgaaagtctcctccaaaacattt ggcaccttggagaaggtgcggctggagttcttacgtctgagtttacctgtcaaatgtcat gactacttctctccaaggggagacaaaggaacaccatcctcagccaccatgtttgaaaga agaatgaactttgagaatgcccgtcgtcatggatacgattcctttgatgggatggtgaat ggcgatacgtacagtgacgctaacatcagtgaggcatcgtttgaggagagcacaagggct tacccagatgatgaggactattccccaaggggtatggccaatgggggcccagacctcacc ctcaggaaaacaattcaccgtggttacacagaggatgaatctattggtgcccaggatcgc aggaagacctttcgacagacatccaaggcgggtcaggctcatcattccttggacgacagg ggtgttcaacaacttctacctggccagatcaaacctgcagccagcgagtcgcatctggac cacgagggcaaaaacacactgtcagtgcctggcaggaaggagcgatcgggatctaaggta tccttgtcaggactcatggacaaaatggctagcacagtcaaaggtggcagcagtgagatg gacaagactggcaagagaggcaagtctccattcacagccatcttcaggaggtctaagtcc cgcgacccgtcaccgtcaggacgcactcccaagacggagaagcgagggtctttccgtgtg cccagagatcagtccggggccggtcgctcccagaccttacccccaaagattgtctccagc gctgacggggatgtaggtccaagtctggaagctcccaaaagcttcataccttacgagttc caagatgccatcgggggtcgccagatgccacgaaacttcagccagaattccatggatgac cttgacttacagagtgacgaggagctgaatgagttaaatgccttagctcaggatgtccat gagtatcactacgctgtgcggatcttcccggggcaggacccctcccaggtccatgtgggc tgggtcacctcaagcttccacggtctcagcaaaacttttgatctgaagaaaatccgccat gtcattgtatctacattagacatggattatgccataaaacagagtgtcagtcgtaaggac tgttacatggtgtctgcaggtgaccttcaacagcggtacggtggtgctcaagacaacatg tcttccaaacgtgcatctccaggccttctgattggctgcaccattgatgctgcctcagga ctgctaagcttcagtgtcaatggcaaggaagtggctaataaatttcaggtggagccaggt gtcagtctcttcccagctgtgatctgtgaaccaacaatcaaggaaatgttccagtttgag ctaggaagaacaaagcacaccttacccctgtctgctgctgtgttccgcggccctaagagc attgtgcccagttgtcccacccgcctggacgtacaggtgatgaaggagtcacactggggg cgtgtgccagactctaccgtcagggttcacattctcaaactgtctgacatcagaggctgg agtgccttctgtgaggagccagtgtcaatgcttgctgtgcacatcccggaggagaatcgt tctctggatatcctggagctgaaggagtacacagaccttctcacgttccatgctcggacg ctggatttgtaccaggcagtgtgttcccatggcaaccataaagtggccaatgtgctgaca agtcatgtagatgagagacagctgatgcactgtatccgcagtgaatatctggctggccca atacgccatggtttccacaacctgctgatatctctccacctggaatcacatgcccactcc agactgctgacccagaacgagtttatcgtgcccctgacagtacagacacgctctctaagc ctgttcagacgacccagtcctacgtcagatacatacaagatcaaacacagcatccctgtc atggagaagagcgtttccatcaggcctgagctcagcatcggcaaggaggcagagcataag gctaaggtaggatttaaggatcagctggcacccgtcttcccagtggctcagctcaaacgt cacgtgatgaaatccctgacggaggccgtcagtaagggagctgcccacatcagggaccct atcgggggtagcaatgccaacctctttgtgcctctgctgaaggtgtgtgataatttacta gtaatgggattgctggatgacgatgacctctaccatctcctctgcctcattgaccccacc tcctttgatgagaagtacgatagacgtcaaccaaagactggactactacacatggtgtta gctgaagatgttaaacttgagctgtgtcatatcctgcagcatatctgcgactgtcagctc agacacagggtcgagtccattgtggcatttgctgatgactttgttggagagagccaaaat gaccagctacggaggtatattgagataaagcaggcagatttaccgtcggccatcactgcc aagaaaactagagagtttcgctgtccacctcatgcacagatgaaggcgttgctggcattt aaggtagaggaggaggaagaagagaagcagtctccttgtcgcgaggacatgaaggagtcg ctgaggtgtttccactcagacctgctgcgtcactgcaccattcccactatccaggagcca gagaagacccaggatgtggtcgccgaggagaagactacgtctgtgtcagagaaacttctt cagctcgtctggaaggtgaaggaagacgacaagaatgattatctggatgacgtggagaaa ccagactcgctgcagaccctgataggtcgcaccatggtgaggtgggccgaggagagcttc atacagaaccaaaatctggtacgagagatgttcagcctgctccatcgacagtatgacggg gtcggagagttgttacgtgccatggacaaggcctatgtgattagcagcgcgagtaaggag gacatcaatcatctgctcaaggccctggggcacatacgctccctgctctcagtccaggct ggacctgatgaagaggagatgatgaaaaacagtctcaaagagctgatggacaataaggtg ttcttccagcaccctgatctgatgagggctctgtgtgtccacgagacagtaatgcagctg atggtgaacacccttaacaaggcccaacaacaacagtctgctgccatagggggcgccact gagcttagcaccagtcagaacaaaccgactgtggtgacagccgcctcagatagcctcatc gaaccatcaaaggacgctgcagcggagatggtggtgatgtgttgtcggttcctgtgttac ttttgccgcaccagtcgtcagaaccagagagccatgtttgatcacctgagctacctgttg gacaacagcagtatgctcctagcccgtccttccctccgtggctcctgccccctggatgtg gcatattcctccctcatggacaacaatgagctggccttagctctgcgagagtctcacctg gagaagattgccatgtacctgtccaggtgcggtatccagtctaatgctgagctgacagaa aaaggctacccagacattggctgggatcctgtggaaggagaaagatatctggacttcttt cgcttctgtgtctgggtcaatggtgagagtgtagaggagaatgctaaccttgtggtacgt ctgctgattcgtcgccctgagtgcctgggccctgccctgcgtggtgaggggggtggctta ctgaaggccatgagggatggcatcaagatgtcagagcagatcactgctgccagggacagt aactcttcacagttcctcacagccgtcaatgatgatgatgatacggggggacagtatctc ttccagagtaaatatgacttttccctcctgccccctgaggatgatgaggattacattgac atgggtggggccatcctcaacttctactccagtctggtcgacctgcttgggcggtgtgcc ccagacgccgagaccatcaaggctgggcgcagcgactcactgagggccagggctattctc aggagtttggtgtccatggaggacctggagggagttctaggcctgcagttcatccttccc gtgggacccccagcaccacctgggggagcctctaccagcagtaatgacgatgggggtggt gccttgggtgggggaggtttacccccagggttactgcccatccacaaggcatccattgtt ctgttcttggagagagtctatggcatcccagatcagacgaccttcttccgactgctggag gatggcttcctgactgacctccgcgctgccactacacttgacacggcggttgcctcagag agtgacatggccttagccttgaaccgttacctgtgtgcctcggtcttgcccctgctcacc acccacgctcatttcttcaatgacgctgaccatgtgtcctccctgattgactccaccctg aacaccgtctataggctgtccaaatgccgctcactcaccaagggacagagggacattgtg tctgactacctggtggcctttacaaatcagctgcgccctccctccatgaccagactgctg aggaagttagcagtggatgtcccggccctgtcagagaacgctgttgtaccactgaggttg ttgacccattactttgagcggtgcggtcggtactacagcagcgggggctggggcaccctg gggtccgcctcagaagaggagaaacgccttaccatgatgctcttcagtggcatatttgac tccttggctcagagggcctatgatccagagttgttttcccgagctttgccctgcctgtct gccattggctgtgccttgtcacctgactactccctgtcacaccaagatgagaactggtac cgccagatgagtgtggatgctgatggaggttacaacccaatgccagtcaacacatcaaga gtggccttggcgggagccctggatcttgtggtgaacaagtttgctgaacactaccatgac tgctgggctctcaagaagattgaccagggctgggtgtatagcagtgtttatgatgatgac aagaaacaccacccactgttgaaaccttaccatctcttgtcagaaaaggacaagatgaag tacacagagcctgtgcgtgagtccctgaaggccatgttgacctggggctggacgctggac caggaccaggcaaggttcacctccaacagagacagtatgaagaggaggggctcaaaggca cagtttgagcatggttacagcccccgaccttatgacctgcggaacatgacgctgaccagg gagacacagacattggcagagagaattgctgagaactctcatgactcctgggctaagaag aagaaggatgagctggatgctattggtgggggtgtacacccacaactggtgccctatgac attctcactgacaaggagaagaggaaggaccgcagtcaggcccaggaactcctcaagttc ctacagttcatgggctacaggatccacagtacggacatggaattgggaggtatgcgtcgt gactctcattccagacagagtaaggagtcggaggcagacagtggggtaggggtttccgcc acagagaagcgcttcgcctacagcttactggagaaactactggagtacctggacaaagcc tctcagaacatgaagcagaacaaaccgagcagtcgctacagtcgtcgcggcagctacaca accgccaccgaggatgtcaagttctttggaaaggtggtgcttccctttgtggagcgctac ttccacgcccacaggctctacttcatcgcctcccccagctctccccagagcagctcagga ggtatggcatctgccaaagagaaggaaatgacagccagtttgttctgtaaactggcgcag acactgaggtctaagatcactgcctttggtcatgatgtcaacatctctgtgcgatgtcta caggtgctagtccaagctgtggatgccaggtctgtggtgaaaaacagcccagaaattgtg cgtgcttctctattgcctttcttcaacaacgcagctgatgatttgaatcaggtggttgac aacctgagccgtgggcggttcagccacatcaaggggacaatcacaaaaggagccaccagc cttaatatggtgcacatggttttacttcctgtcctctcctccatgtttgatcacctaggc aaccagcactacggcagtgacctcatcgttggggagatccaactggcctgttacaggatc ctcaactccctgtatctcctgggtacaagcagttcttctgtcgtacagagagagacgttc caggcagaattagccagacaccgcccagctcttggggaatgtgtaggctcttttgccacc tgtttcccagtagccttcctggaaccccacctgaacaagtacaacaagcactccatgttg tttggcctggaggggaagatcgctgaccactccttagaggctcaagtggtaatggatcag ctggtggagaacctgcctaacctggagaagatcgtggctgagatagaggagctggccgag tctggggggaagtaccaggaagcaccccatgtgattgaggtcacactgcccatgctctgc agctacttgccagtgtggtggtcacaagggccagacaaagtgccgtctgaaaggggtcat catacgacgtccgtaacagctcaactcatgaacagtgtccttggcaatgtcctcaaactt atcctcaacaacattgcctctgaaaatgctccatggatgaaacgaattgccactcgcacc cagccaatcatcggtaactccacccctgacatggtgcgtgaccactttttgccggtggct caaaagttgcgtgacaacgcgaagacggtggaacaggaggagaggcggctgaatcaggac cgtaagatcatctctgaggtggctgaccaggaagcccgtgtgcaggagcgattcagcata ttcgtgagggacatctatgccttctacccactgcttatcaaatatgtggatctgcaccgc tctcattggctgaaacacccaacggctgaggcagaggaactgtttagctgtgtggcgaac atcttcttactctggtccaaatctgtgatatttcgtagagaagaacaaaactttgtaaca caaaatgaaatcgacaatttggctctgatcatgccaagtcaagctaagcgcctctccccc tctaaggtggatcagaagggaggtcagaaaggctctgctacagataagatgaggaaaaag gagaagaagaagttagagtctcacaacagtctgaacgtggcctgtctgaagcgactactt cccatcggcctcacggtgtttggcgggaaagaacaggagcttgtgcaacaagccaagcag aaactcttccagaaagaatcagatggggatgtggaggaattcttactgctgagcctggaa caaggagaggacgcgtctgagaaagacgagaaggtacaatggcagaagctgctgtacaag aaaattgggaccaccaagctggaggggatatcccagctgaaccaagccaagatcgtagag aagatcctgtccatggctaaagtcttacacggactacatctggttgagcacccacctcca tctctgaagaacgcctggaagaaggtgatctcgacccagcgcaagagggcggtgatggct tgcttcaggatgataccacttcatggactgcccaggcaccgagctatcaacttatttttg agatcttacaaacaacagtggctgaacatagactatatggaagaggagaaaaacaccttg attgaagatatcacacacaacaaagaagaagaagagatggaagccgtagagaagaaggag ttggaagaggagataactcctgactccttgactcagctgatcacggccctgagccgagcg gccacaaaggagcagcagtccagcatccctgaagatttcctgtatatgtcctacgctgac atcatgagcaagagctgcagcggggaggatgaagatgacgaggaagaaggaggagaagat gccggctcctctttccaggagcaggagatggagaagcaaaagctgctgtttgagcagtca cggctggctgaccgcggggctgctgagatggtgctactttatattagtgccagcagaggt gtctctggagaaatgacatctagcacaattgaactgggtatatcattactcaggggaggt aaccaagatgttcaaaagagcatgttaaaacacctgagggacaagaaggatgttggcttc ttcacctctctggcaggtctgatgcagcagtgcagtgtgctggacctggacgcatttgag cgctgtaacaaggctgagggcctggggatgagctctgatgcaggtgcaggagagaagaac ctccatgatgctgaggacacgtgtaaactgtttaggttcctacagctgctctgtgagggc cacaacctagagttccagaattacctgaggacccaggcaggtaacacgacgacggtcaac attattatctgtacagtggattacctgctcagattacaggagtctatcatggacttctac tggcattattctggtaaagatatcatcgattctgcgggtaaagataatttctgtcgagca atcaaagtggccactcaggtgttcaggacccttactgagtacatacagggtccgtgctcc ctcaaccagctggccctggcacacagtaggctttgggatgctgttggaggattcctctac atctttgcccacatgcagaataaattatcaaaggatgctgatcaactggaactcctccga gaattcatgaaactgcagaaggaaatgatgatcatgttgctgtccatgttggaaggcaat gtgatgaatgggccaatcggaaagcagatggtggatactttggtcgagtcatcggccaat gtggagatgattctgaaattcttcgacattttcttgaagatgaaagacctgaccacttct gaagctttcctggagtttgatactaataaagatgggtggatttcgtgcaaagaattccgc agggccatggaagctcaaaaagtttattcggatgaggagatagattacgtgatgatgtgt gtggatgctaaccaggacggcaaagtggacttccaggagtttacagaccgattccacaac ccagccaaggatatcggcttcaccatgtctgtactgctgaccaacctctccgagcacatg accaacgacccaagattggataagatcctggagaaagccaaacccgtcctggactacttt aacatgtacctgggtcgtattgagatcctgggaagcagtaataggattgagcgcgtgtac tttgagatcaaacagtctcatattgaccaatgggaaaagccacagatcaaggaatctaaa cgctcgttcctccacagtgtggtcaatgaagggggtgacaaggagaagctggagagcttt gtcaatttctgcgaggacaccattttcgagatgcagcatgccacaagcatcagtgctgag gaacagaggctagcagctctgaaggccggccagggtgaagatgttggtgtcctggagcct gtcaggatgatgttccggtttatccgtgatggactcggtacaatcctctcactcttcacc tggagtaacataaagacaggctacaaaaccttcaagtccatgacgtacttccaactgctg gtggccttcctcaaaatgaacattcgtctcactttgctgctccttaccttcctcttccat gttgcctggacactgtgtaagtttctggctaacatgatgatgggggagaagccatcagat gacccagtccaggataagaagggtccccctgccctgacagctgggccaatggtgctgcac aacacgggccacccaggtggggggtacggtgggggcctgcccttctatgagccggagata catgtgcaaccctccagtgcattcggcattatcattactaacaaagaggagacaactcag tctgatgagtccgccccacccccaggagacatgggctcaggattacaacccaccactgca agcaaggatgctaaacctgcctcagctaaggctccatctgtgaaacaaactcagtggtcc tcacaatcaggggaggcaacttcggatgaggaggagcccctgctaagggaagaggaaacc ccagagaccagtagaccacctccaaggaagccttattctgatgttccagttggtttcatt ggagaatgggcgtttgtacccggctctgacccatcaagttcaacatcagctcaagaagaa gatgtgctggtcgaaccgagaagctttgactacggcaaatacatcttgagtctttttgct cggaatttctacaacttcaaatacttaggactggccatatcctttctgatcaatatcatc ctgctgttctacaaggtatccaaggtgactggagagggtgtagaaggtggggcaggtaat gacacttctgacgatgacgtggaagagtttgtggtgatagaggaggatgtgagttacttg gagcccatcatgcggacgctggcctttgtccactcacttgtctctctctccatgcttgtg gcctactattgcctcaaagtcccactggttatattcaagcgtgagaaggaaattgcccga atgctggagtttgagggactgtggattgctgaacagccgagtgaagatgacatcaaatgt cactgggacaagctcgtcatcagcactgtatccttcccacaatcttactgggacaaattt gttaagaaaaaagtgaggaacaagtactcagagcagtatgattacgagtctatcagtaat ctcctgggaatggataagggagactcaatcacgatcagcacagaggaacaacaacagtcc ggcatcctcccgtcctttctatgcaatgttgattggcagtaccagatctggaagtggggt gtcatattcacagataattcgttcctctacattatgggctactttatattctcggtgtgt ggaaatttcaactatttcttctttgctgcccatttgctggatgttgctattggcttcaaa accctgagaaccattttgcagtctgtcactcacaatggaaaacagctggtgttgacagtc atgctaaccagtgtggtggtctatctttacactgtcgtagccttcaacttcttccgtaaa ttctatgtcaaggacgaagatggcaacgttgattacaagtgtcatgacatgtgcttgttt gtctgttacagtgtttttgtgtatcacctgcatacaggtgtcagagctggaggaggtata ggagatgagattgaaccagcagatggcgatgcttacgaagtacccagaattctctttgac ataacatttttctttttcgttattgtcatcctgttggctattattcagggtttgatcatt gatgcctttggagagctgagagaccagctagagcaggtgaaagaggatatggagtccaaa tgtttcatctgcggtatagggaaggagtattttgataaagtacctcatgggtttgagact catgttcagaatgagcacaactttgccaattacatgtttttcctgatgcatctcatcaac aaacctgatacagagtatactggtcaggagtcgtacgtttgggagctgtaccagaacaga agctgggacttcttccccgtgggtgactgctttaggaaacagtatgatgatgatgcggcc aaagatcactga

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