Lactococcus lactis subsp. cremoris SK11: LACR_0388
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Entry
LACR_0388 CDS
T00420
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
llc
Lactococcus lactis subsp. cremoris SK11
Pathway
llc00300
Lysine biosynthesis
llc00550
Peptidoglycan biosynthesis
llc01100
Metabolic pathways
llc01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
llc00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
LACR_0388
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
LACR_0388
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
LACR_0388
Enzymes [BR:
llc01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
LACR_0388
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ABJ71995
UniProt:
Q031X7
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Position
354729..356051
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AA seq
440 aa
AA seq
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MKLTIHEIAQVVGAKNDWSQLADLSVNKIEFDSRLIEKGDIFLPLKGARDGHDFIEIAFD
NGAIISFSEKEVEQAHLLVDDNLAAFQTLAKYYLEKTKVPVIAVTGSNGKTTTKDMIAAV
LSKKYKTYKTQGNHNNEIGLPYTILHMPEDTEKLVLEMGMDHPGDIDFLSQLAQPELALI
TLIGEAHLEFMGSRENIAKGKMGITAGLHGELIAPADPIINAFIPENQKISRFGLPGEDL
FITKLIEHKERLTFETNFLDESITIPVPGKYNATNAMLAAYVGLHYGLTEAEIKNALKEV
ELTRNRTEWNKSKNGADLLSDVYNANPTAMRLILETFQAIPKNENGRKIAVLADMLELGP
TAAQLHKEVLKSIDFTKIDKVYLYGEMMKNLADISTDKPVSYFTDLDLLTESLSADLKPA
DQVLFKGSNSMKLSEVVEKL
NT seq
1323 nt
NT seq
+upstream
nt +downstream
nt
atgaaactcacaattcacgaaatcgctcaagtcgttggcgcaaaaaatgattggtcgcaa
ctggcagatttgtcagtaaataaaattgaatttgacagccgtttaattgaaaaaggagat
atctttttgccactcaaaggggcacgagatggtcatgatttcatcgagattgcttttgac
aatggagcaataattagcttttcagaaaaagaagttgaacaagctcatcttttggttgat
gataatctagcagctttccaaacattagcaaaatattatctggaaaaaacaaaagttcca
gttattgcggtgaccggctcaaatggtaaaacaaccaccaaggatatgattgctgctgtt
ttatctaaaaaatataaaacctataaaacacaaggaaatcataataacgaaattggattg
ccttacacaattttacacatgccagaggatactgaaaaattagtattagaaatgggaatg
gaccaccctggcgatattgattttctctcacaactagctcaacctgaactagctcttatt
accttaattggtgaagctcatcttgaatttatgggtagtcgtgaaaatattgcaaaaggt
aaaatgggtattactgctggtctacatggtgaattaattgcccctgctgacccaattatt
aatgcttttattccagaaaatcaaaaaatcagtcgttttggtttgcccggtgaagattta
ttcattacaaaattaattgagcacaaagaaagattgacttttgaaactaattttttagat
gaatcaataacgattccagttcctggtaaatataatgcaacgaatgctatgttagctgct
tatgttggcttacattatgggttgacagaagctgaaatcaaaaatgctttgaaagaagtt
gaactgaccagaaatcggacagagtggaacaaatctaaaaatggagctgaccttttaagc
gacgtctataatgccaatccaacagctatgcgcctgattttggaaactttccaagccatt
cctaaaaatgaaaatggtcgaaaaatcgcagttcttgctgacatgttagaactcgggcca
actgctgctcaacttcataaagaggtgctgaaatcgattgatttcacaaaaattgataaa
gtctatctttatggcgaaatgatgaaaaatttggcagatatttcgactgacaaacctgtc
agctattttacagatttggatttactgacagaaagtctgtcagcagatttgaaaccagca
gaccaagttttattcaagggttcaaacagcatgaaactttcagaagttgttgaaaaatta
taa
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