Lactococcus lactis subsp. lactis KF147: LLKF_1183
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Entry
LLKF_1183 CDS
T01141
Symbol
folC
Name
(GenBank) Folylpolyglutamate synthase / Dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
llk
Lactococcus lactis subsp. lactis KF147
Pathway
llk00790
Folate biosynthesis
llk01100
Metabolic pathways
llk01240
Biosynthesis of cofactors
Module
llk_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
llk00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
LLKF_1183 (folC)
Enzymes [BR:
llk01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
LLKF_1183 (folC)
6.3.2.17 tetrahydrofolate synthase
LLKF_1183 (folC)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
ADA64884
UniProt:
A0AAN0P2A4
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Position
1194380..1195663
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AA seq
427 aa
AA seq
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MSIEEALEWIHSRLKFNIRPGLSRVSALLELLGHPEESLSMIHVAGTNGKGSTVAFTRSI
FMQAGLKVASFTSPFITTFGERMSINALPIADDKLIYYVEMIQPLVAELDKDAELTGITE
FEIITAMAFKYFSDEQVDLAVIEVGLGGLLDSTNVIKPVVSGITTIGLDHIDILGSTIEE
IAAQKAGIIKPGIPVVVGNIELKALRVIWEVARKNTARVYQFPYDYRTEVEEHEHFNFFS
GQEAILDIEKSLVGLHQIENAGMAIELSLVYASKVGIELTEDVIRSGIREAFWPARMEKL
GEKPLILLDGAHNAHAMNRLLENLSSEFPDKKITIIFSAIITKDISQMIKMLQTVKNSHL
ILTTFDYPKALNLGDFQRLEEEGVELAPSWELALVRAQKNLAEDDLLLVTGSLYFSSQVR
EFLKKEK
NT seq
1284 nt
NT seq
+upstream
nt +downstream
nt
atgtctatagaagaagcattggaatggatacattcacgtttaaaatttaatattcgccca
ggcctaagtcgtgtttcggcccttttagaattgcttggtcatccagaagagtctttgtca
atgattcacgttgctggaacaaatggaaaaggctccacagtcgctttcacacgctcaatc
tttatgcaggcaggtctgaaggttgcttctttcacaagtcctttcatcaccacttttggt
gagcggatgtcgattaatgcactcccgattgctgatgataaattaatttattatgtagaa
atgatccaaccacttgttgctgaacttgataaagatgctgaactgactggaattaccgaa
tttgaaattatcacggcaatggcttttaaatatttctctgatgagcaggttgatttagcg
gttattgaagttggtttaggtggacttcttgattcaacaaatgtgattaaacctgttgtt
tctggaattacaacaattggtttagatcatattgatattcttggttcgaccattgaagaa
atcgcagctcaaaaggctggaattattaaaccaggaattccagtagttgttggaaatatt
gaattaaaagcacttcgggttatatgggaagtggctagaaaaaatacagcgcgtgtttat
caatttccatatgattatcgtacggaagtggaagaacacgaacattttaatttcttttct
ggtcaagaagcaatattggatattgaaaaatctttagttggcttacatcaaatagaaaat
gctggtatggctattgaactttctctggtttatgcaagtaaggttgggattgaattgact
gaggatgtgattcgctctggaattcgtgaggctttttggccagctcgtatggaaaaattg
ggtgaaaaaccactcattttactggatggtgctcataatgctcatgcgatgaatcgtttg
cttgaaaatcttagctctgagtttccagataaaaaaattacaatcattttttcagccatt
atcacaaaagatattagtcaaatgataaaaatgcttcaaactgtgaaaaattcgcatctg
attttgacaacttttgattatccgaaagctttgaatttgggagattttcaaagattggaa
gaagaaggggttgaattggctccaagttgggaattagctttagttcgtgcgcaaaaaaat
ttagctgaagatgatttgttattagttacaggctctctctatttttcatctcaagttcgt
gagtttttgaaaaaagagaagtaa
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