Lutzomyia longipalpis: 129796019 Help Entry 129796019         CDS       T10428                                  Name (RefSeq) ryanodine receptor   KO K04962   ryanodine receptor 2 Organism lll  Lutzomyia longipalpis Brite Ion channels [BR:lll04040]  Voltage-gated cation channels   Ryanodine receptor    129796019 Domain-containing proteins not elsewhere classified [BR:lll04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    129796019 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR SPRY Ins145_P3_rec MIR RR_TM4-6 RIH_assoc Ion_trans EF-hand_7 DUF996 Motif Other DBs NCBI-GeneID:  129796019 NCBI-ProteinID:  XP_055693636 LinkDB All DBs Position 4:complement(10824389..10854600) Genome browser AA seq 5141 aa AA seqDB search MAEAEGGSEQDDVSFLRTEDMVCLSCTATGERVCLAAEGFGNRHCFLENIADKNIPPDLS QCVFVIEQALSVRALQELVTAAGSETEKDSLGKGTGSGHRTLLYGNAILLRHQNSDMYLA CLSTSSSNDKLSFDVGLQEHSQGEACWWTVHPASKQRSEGEKVRVGDDLILVSVATERYL HTTKENDQSIVNASFHVTHWSVQPYGTGISRMKYVGYVFGGDVLRFFHGGDECLTIPSTW ANEPGQNIVIYEGGSVMSQARSLWRLELARTKWSGGFINWYHPMRIRHLTTGRYLAVNEN NELCLLAKDEATISCSTFCLRQEKDDQKIILEDKDLEIIGSPIIKYGDSTVIVQHLESSL WLSYKSYETKKKGVGKVEEKQAALHEEGKMDDGLDFSRSQEEESKTARVIRKCSSLFTKF INGLERLQEHRRHSIFFQTVNLSEMVMCLEDLINYFAQPDDDMEHEEKQNRFRALRNRQD LFQEEGVLNLILEAIDKINVITSQGFLASFLASDESGQSWELISGYLYQLLAAIIKGNHT NCAQFANTNRLNWLFSRLGSQASSEGSGMLDVLHCVLIDSPEALNMMRDEHIKVIISLLE KHGRDPKVLDVLCSLCVGNGVAVRSSQNNICDFLLPGKNLLLQTQLVDHVASIRPNIFVG RVEGSAMYQKWYFEITMDHIEQTTHMMPHLRIGWANTSGYVPYPGGGEKWGGNGVGDDLY SFGFDGAHLWTGGRKIAIVSAELQEPYIRKGDVIGCALDLTVPIITFTFNGARVRGSFRN FNLDGMFFPVLSCSSKLSCRFLLGGDHGRLKFAPPLGFSPLVQCLMPHQVLSLDPCFYFG NLNKNVLAGPWLVEDDTPFVPQPVDTTNVGLPSFVDTIKDKLAENIHEMWALNKIEAGWC WGEYRDDLHKIHPCLTQFERLPAAEKRYDCQLAVQTLKTIIALGYYITLDKPPARIRPIR LPNEPFMQANGYKPAPLDLSAVTLTPKLEELVDQLAENTHNLWAKERIQQGWTYGLNEDS ENHRSPHLVPYAKVDEAIKKANRDTASETVRTLLVYGYNLDPPTGEGNEALLAEAQRLKF AAFRTYRVEKNYAVTSGKWYFEFEVLTAGPMRVGWARADCNPGTMLGNDDSTWAFDGYNE EKVSGGSTESFGKQWVPGDVVGVFLDLVDHTISFSLNGELLMDALGGETTFADVTSDGVG FVPACTLGVGQKARLIYGQNVDSLKWFTTCGLQEGYEPFCVNMRRPVTHWYTKDQPIFEN TEDFIDCRIDVTRIPGGADTPPCLKISHNTFETMEKANWEFLRLSLPVICQSTFITENEK MRRWEEIKMRQNRILAEAEQTTPAHFDHIMRSGFTMNDIKGLHRNYNEDAAEADEQMLRP NPSRPPRKGSLSRGSIAAYDPPSIEINSKIQRSTSELDMNAYGEIGDKDDKKKRGRSPFK FFSKKRDQSKDKLKAKTPEPADRRSTQGRNVIQSQTMTRAPTVRVSNADLRVQPPAVPDR PKTMTVNSLGGSPIEAVGNEVYDSECLKLINEYFYGVRIFPGQDPTHVWIGWVTTQYHRH SNEFNQQTVRRISVTMEDDYGSIADQVNRQSCYMVRSDELFNEVTQDASGKGASQGMFVG CFVDTATGTIRFTCEGKETSHKWVMEPDMKLFPAIFVEATSKEVLQIELGRTPTTLPLSA AVLPTGDKHVNPQFPPRLKVQCLKPHQWARVPNNALQVHALKLSDIRGWSMLCEDPVSML ALHIPEEDRCIDILELIEMDKLLSFHSHTLTLYAALCYQSNYRAAHALCLHVDQKQLLYA IKSEYMSGPLRQGFYDLLIALHLESHATTMEVCKNEYIIPLGPELAELYKDTEMCHSLRS ITTESVRPQMKMTEIASPLPNVPIVVANGVSSEPIPTIDALYSPRFPLEVVREFVMEALA EAVEINQVHNRDPIGGSNENLFLPLIKLTDRLLLVGILTDQDIEKLLIMINPETWDSNFD KEGKDEHRKGLLTMKMAEGAKLQMCYLLHHLCDIQLRHRVESIIAFSNGFVGDLQADQLR RYIEIKQSDLPSAVAAKKTREFRCPPREQMNAILSFKALEDDDIENCPCGVELRDALNAF HAQLMYTVSLNALQDSEAEDAGAADTGKSGPLSKIFNFINTVKELEEEPVEKGEPVKKTP EEIFRKVLIKTIVSWAEESQIETPKLVREMFSLLVRQYDTVGELIKALEKTYVINSKTKN DVAGMWVGLSQIRALLPVQMSEEEEKLMRTRLWKLVNNHTFFQHPDLIRILRVHENVMAV MMNTLGRRAQAQSDAPVQSEGGEQPVKEKDTSHEMVVACCRFLCYFCRTSRQNQKAMFDH FDFLLENSNILLSRPSLRGSTPLDVAYSSLMENTELALALREHYLEKIAVYLSRCGLQSN SELVEKGYPDLGWDPVEGERYLDFLRFCVWVNGESVEENANLVIRLLIRRPECLGPALRG EGEGLLRAIIDANKMSERIADRRKLQDEAEGTMSGLSFNHPLPESDDDEDYIDTGAAILC FYCTLVDLLGRCAPDSSVIAQGKNESLRARAILRSLVPLEDLQGVLSLKFTLQNPAPGEE KPKSDMPSGLIPGHKQSIVMFLERVYGIETQELFYKLLEEAFLPDLRAATMLDRNDGSES DMALSMNRYIGNSILPLLIQHSKFYNEAENYASLLDATLHTVYRLSKNRMLTKGQREAVS DFLVALTAQMQPSMLLKLLRKLTVDVSRLSEYTTVALRLLTLHYDRCAKYYGSSGGQGAY GSSSDEEKRLTMLLFSNIFDSLSNMDYDPELFGKALPCLIAIGCALPPDYSLSKNTDEDF YGKPASTSAPDQPQYNPQPINTSAVVLDNDLNSIVQKFSEHYHDAWASRKLEAGWSYGEQ WSDSQKSHPRLKPYNMLTDYERERYKEPVREALKALLALGWTVEHAEGDVPLSHRGSTRR TSKPNLEFQGDSSSPFNYNPQPIDMTNLTLSREMQNMAERLAENSHDIWAKKKREELNTC GGAIHSQLVPYDLLTDKEKRKDRERSQEFLKYMQYQGYKLHKPSRGLSVDGEQAGGGPAI ELRFAYSLLEKLIQYLDRATINMKLLKPSTTFSRRNSFKTSSRDIKFFSKVVLPLMEKYF STHRNYFIAVATATNNVGAASLKEKEMVAALFCKLASLLRYRLAAFGPDVRITVRCLQVL VKGIDAKSLVKNCPEFIRTSMLTFFNNTADDLGQTIVNLQEGRYSHLRGTHLKTSTSLAY VNTVILPVLTAMFDHLSACEYGSDLLLDEIQVASYKILASLYTLGTDASLTHDRKYLKTE IERHKPSLGSCLGAFSSTFPVAFLEPHLNKHNQFSLLNRIADHSLEAQDIMVKMEASMPN LEAILQEVDQFVESDKTYNDAQHIIDVILPLLCAYLPFWWAQGPDNLTPTTGNHVTMVTA DHMNQLLKNVLKMIKKNIGNDNSPWMTRIAAYTQQIIINSSEELLKDPFLPLAERVRKRT DNMFHKEESLRGFIKSATDDTSQVEAQIQEDWQLLVRDIYSFYPLLIKYVDLQRNHWLKN NIPEAEELYNHVAEIFNIWSKSQYFLKEEQNFISANEIDNMALIMPTATRRTQVISEGQQ NTGGKIKKKKKDRSKKRDKDKEVQASLMVACLKRLLPVGLNLFAGREQELVQHCKDRYLK KMQEYDVIEFARTQLTLPDKLDPADEMSWQHYLYSKLGKKETEIDEIVEKSKASDDKKPE NKIDDTVDRIVAMAKVLFGLHMANRPKQRSDKWQRIVSLARRKSALACLKAKPLYKLSRH RACNIFARTYHELWLQDENAGQEIMIEDLTQSFEDAEKAKKDAEEEESKPDPLTQLVTTF CRGAMTERSGALQEDALYMSYAQIAAKSCGEEEEEGGEEEGGGEEGESSGASIHKNTMET LMEQEMEKQKLLFHQARLSNRGVAEMVLLHISASKGVPSEMVMKTLELGIAILRGGNIDI QMGMLNHLKEKKDVGFFTSIAGLMNSCSVLDLDAFERNTKAEGLGVGAEGAAGEKNMHDA EFTCALFRFIQLTCEGHNLEWQNYLRTQAGNTTTVNVVICTVDYLLRLQESIMDFYWHYS SKEIIDPAGKANFFKAIGVASQVFNTLTEVIQGPCTLNQQALAHSRLWDAVGGFLFLFSH MQDKLSKHSSQVDLLKELLNLQKDMITMMLSMLEGNVVNGTIGKQMVDTLVESASNVELI LKYFDMFLKLKDLTSTPSFQEIDPNGDGWINPKDFQDKMEQQKSYTPEEIEFLLACCETN HDGKIDYIDFVDRFHDPAKEIGFNLAVLLTNLSEHMPNEPRLARFLETAGSVLNYFEAFL GRIEIMGSSKRIERVYFEIKESNIEQWEKPQIKESKRAFFYSIVTEGGDKEKLEAFVNFC EDAIFEMTHASALMATDEGGASVRREASFSTYISEEEEEKAAKDPIKRTVQGFKDGFWFI LHFFSVSNIKHQIAVAQTKSIPELFVGFFKMIFYAFYYSGYGVALIVKYFLNVLMSLMRG SGTEEAEPEPVPEATGLMRALPALPQEEPPGTVQAFGLDISKEENGQYKLAPHESPAASP SSSMEETGESSPEDAAAAGEHATEEGQEPPITLVDLLGGEAAKRAAQERSEAQKLQEAAM ATIEAESKKSSAEPKEPAAVTQIDFSQYTHKIVSFLARNFYNLKYVALVLAFCINFMLLF YKVTTFGEDEGGSGEGELDMEFGSGGSGSGLGALLEGSGLDMDGEGGEEEDPLESVHVDE DFYYMEHVLRIAAFLHSTVSLAMLIAYYHLKVPLAIFKREKEIARRLEFDGLFIAEQPED DDIKSHWDKLVISAKSFPVNYWDKFVKKKVRQKYSETYDFDCISNLLGMEKSAFTAQEAE GGGLVHYIVTIDWRYQIWKAGVTITDNAFLYSLWYFTFSIFGNFNNFFFAAHLLDVAVGF KTLRTILQSVTHNGKQLVLTVMLLTIIVYIYTVIAFNFFRKFYVQEEDEEVDKKCHDMLT CFVFHLYKGVRAGGGIGDEIGDPDGDDYEVYRIIFDITFFFFVIVILLAIIQGLIIDAFG ELRDQLESVKENMESNCFICGIGKDYFDIVPHGFDTHVQKEHNLANYMFFLMHLINKPDT EYTGQETYVWNMYQQRCWDFFPVGDCFRKQYEEELGGGSGG NT seq 15426 nt NT seq  +upstreamnt  +downstreamnt atggctgaagcggaaggaggatctgagcaagatgatgtttcattcttgcgcacggaagac atggtttgtctttcgtgcacagccacaggtgaacgtgtttgcttagcagcggagggtttt ggcaatcggcattgtttccttgaaaatattgccgataaaaacatccctcctgacctatca caatgtgtcttcgttattgagcaagctctctccgtgagagcactgcaggagctcgttaca gctgcaggatctgagaccgagaaagattccttagggaaaggaacaggatccggtcacagg acactactctacggtaatgctattcttttacgccaccaaaacagcgacatgtacttagct tgcctgtcgacgtcgtcctcaaatgacaaattgtccttcgatgttggtcttcaggagcac agtcaaggcgaagcgtgctggtggacggttcatccggccagcaagcagaggtcagaaggt gaaaaggtgcgtgtcggtgatgatttgattctcgtatccgtggccactgagcgatacttg cacaccaccaaggagaatgaccagtccattgtcaatgccagcttccacgttacacactgg tcagttcaaccctatggtacgggaatttcgcgcatgaagtatgttggctatgtctttggc ggtgatgtcctgcgattctttcacggtggtgacgaatgtctaacaatcccgagcacgtgg gcaaatgaacctgggcaaaacatagtgatatatgaaggaggttctgttatgtcacaagca aggtccctatggcgcttagaattggctcgtacaaagtggtctggtggctttataaattgg taccatccaatgaggattcgtcacctaacaacaggacgttatttggctgttaacgagaac aacgaactatgcttgctggcaaaagacgaagcaacaatttcatgctcaacattttgcttg cgtcaggagaaagatgatcaaaaaattatccttgaggataaagatttggaaataattgga tccccaattataaaatacggtgactcaactgtcattgtacagcacttagagtcgagtctc tggttgagctacaagagctatgagacgaagaagaagggcgtgggaaaggtggaggagaaa caggctgccctgcatgaggaaggaaaaatggatgatggtctggatttctcacggtcccag gaagaggaatccaaaacggcaagggtaatccgcaaatgcagtagtctcttcacgaaattt atcaatggtcttgaaagattgcaagaacatcgacgtcactcaatattctttcaaactgtg aatttgtccgagatggtgatgtgtcttgaagatctcatcaattactttgcccaaccggac gatgatatggaacacgaagagaagcaaaacagatttcgtgctctgcgaaatcgtcaggat ctttttcaggaagaaggcgtgttgaatttaattctcgaggccattgataagatcaatgta atcacttcccagggatttcttgctagcttcctagcgagtgatgaaagtggtcagagttgg gaattaatttcgggctatctgtaccaattactagctgctattattaaaggaaatcacacc aattgtgctcaatttgccaatacaaatcgattgaattggctattctctcgccttggttct caagcctccagcgaagggtctggaatgctcgatgtactccactgtgtccttattgattca cctgaagccttgaatatgatgagggatgaacacattaaagtgattatatccttgctggag aaacatggtcgtgatccaaaggtccttgatgtcctttgctccctttgtgtgggtaatggt gtagctgtgagatcgtcacagaataatatttgtgactttcttctgcccggaaagaatctt ctccttcagacgcaacttgttgatcatgtggccagcattcgaccaaacatatttgtaggt cgcgtcgaggggtctgcaatgtaccaaaagtggtattttgaaataacaatggatcacatt gagcagacaacccacatgatgccacatctacgaattggttgggccaatacatcgggatat gtcccataccccggaggtggtgaaaaatggggtggaaatggcgttggggatgatctctac tcattcggcttcgacggtgcacacctgtggacaggtggacgcaaaattgccattgtatcg gctgaactgcaggagccttacatccggaagggtgatgtaattggatgcgccctggactta acagtgccaataataacatttacattcaacggggctagagttcgtgggagcttccggaat ttcaatctcgacggcatgttctttcccgtactcagttgttcttccaaattgagctgtcgc ttccttctcggtggtgatcatgggcgcttgaaatttgctccaccactgggattttcaccg ctcgttcagtgccttatgccacatcaagtacttagcctcgatccttgcttctactttggc aatctcaataagaatgttctagcgggaccgtggctcgttgaggatgacaccccctttgtg ccacagcccgttgatacaaccaatgtcggtctaccgtcatttgtggatacgattaaggat aaattagcggagaatattcacgaaatgtgggctctcaataaaattgaagctggatggtgc tggggggaataccgcgacgacttgcacaaaatccatccatgcctaacgcaatttgaacgc ctaccggctgcagagaagcgctacgactgccagctagctgtacaaacgctaaagacaatc attgctcttggatactacattacattggataagcctccagcgagaattcgaccaattcgt ctaccgaatgaaccctttatgcaggcaaatggctacaagcccgccccattggatctcagt gctgtaactttaacacccaaactcgaggagctcgttgatcaattggctgagaatacgcac aatttgtgggcaaaggagagaatccagcagggatggacgtatggtctcaatgaagattca gaaaatcaccgtagcccccatttggtgccctatgcgaaagttgatgaagccataaagaag gcaaatcgggatacggcttcggaaactgtacgaaccctcttggtgtatgggtacaatctt gacccaccaacaggtgagggcaatgaagctcttctggctgaagcacaacgactgaaattc gctgcatttcgaacgtatcgagttgagaagaactacgccgttacatcgggaaaatggtac tttgaatttgaagtacttactgccggcccaatgcgggtcggttgggctagagctgactgc aatccaggaacgatgcttggaaatgatgacagtacatgggcctttgatggatacaatgaa gaaaaagtatcggggggctcaacagagtcctttggcaaacagtgggttcctggcgatgtc gttggtgtcttccttgatttggtggatcacaccatcagtttctctctgaatggagaactg ttgatggatgcattgggtggtgaaacaacatttgctgatgtaacctccgatggtgttggc tttgttccagcctgtactcttggggtgggacaaaaagctcgattgatttatgggcagaat gttgattccttgaagtggttcacaacgtgtggtcttcaagagggctacgaaccattctgt gtaaatatgagaagacctgtaacgcattggtacacgaaggatcaaccaattttcgagaat accgaagactttattgattgtcgcattgatgttacgagaattccaggaggtgctgataca ccgccatgcttaaaaatctcccataatactttcgaaacaatggagaaagccaattgggaa ttccttaggctatcactgccagttatttgccagagtacatttattactgaaaatgagaaa atgcgccgatgggaagagatcaagatgcgccaaaatcgcatcttagctgaagctgaacaa acaactcctgcacattttgatcatataatgcgtagtggcttcaccatgaatgatatcaag ggcctacataggaattacaatgaagatgctgcggaggcagatgaacaaatgctacgtcca aacccatcaagaccaccgaggaagggatccctttcgcgtggtagcattgctgcatacgac ccaccaagtattgagattaattcaaagattcagaggtcaacaagtgaattggatatgaat gcctacggtgagattggcgataaggatgataagaagaagcgtggcaggagtccgtttaaa ttcttctcaaagaaacgtgatcagagtaaggataaattgaaggcaaagaccccagaacca gctgaccggagaagtactcagggaagaaatgttattcaatcgcaaacaatgacaagagct ccaacggtcagagtgtctaatgctgatttaagagttcaaccacctgcagtgccagatcgt ccgaaaacaatgaccgtgaattctttgggtggtagcccaattgaggcagttggcaatgaa gtctatgattcagaatgtctcaagctgatcaatgaatatttctacggtgtacgaatcttc ccgggtcaagatcctacgcacgtgtggattggctgggtaaccacacaatatcacaggcac agcaatgaatttaatcagcaaactgttcgccgtatctccgtaacaatggaagatgattac ggaagtattgcagatcaggtgaatcgacagagttgctacatggtgcgttcggatgaattg ttcaacgaagtgactcaggatgcatcggggaagggtgcatctcagggtatgtttgtgggg tgcttcgttgatacggcaacgggtacaattagatttacgtgcgagggtaaggaaacctcc cataaatgggtcatggaacccgatatgaaactctttccggctatttttgtggaggctaca agtaaggaagtgctccaaattgaattgggtcgtaccccaactaccctaccattgtcagct gctgttctaccaaccggggataagcatgttaatccccaatttccaccaagactaaaggtg caatgcctaaagccacatcaatgggctcgtgtgcccaacaatgccctccaagttcatgcg ctgaaactctccgacatacgtggttggtctatgctatgtgaagaccccgtatccatgctg gctcttcacattcccgaggaggatcgttgcattgatattctggagctcattgaaatggat aaacttctctccttccactcacatactctaacactctacgcagcactttgctaccaatcg aattatagagctgctcacgccctatgccttcatgtggatcaaaagcaactactctatgcc atcaagtccgaatatatgagtggtcctttgcgtcaaggtttctatgatcttctcattgca ctacatttggaatctcacgccacgaccatggaagtctgcaaaaatgaatacatcatccca cttgggccagaattggcggaactgtacaaagatactgaaatgtgtcattcactgaggtca attacgactgaatcagtaaggccacagatgaaaatgactgaaattgcctcccctttgcca aatgtaccaatagtagtggccaatggtgtttccagtgagcctataccgacgattgatgcc ctgtattcaccacgcttcccattagaagtcgtcagggaatttgtaatggaagccctagca gaagccgttgagatcaatcaagtacacaatcgggacccaattggtggatctaatgaaaat ttattcctgccattgataaagctaacggatcgtcttcttcttgtgggaatactgacggat caagatattgagaaactcttgataatgatcaatccagagacatgggacagcaacttcgac aaggagggcaaagatgagcaccgaaagggtcttttaacgatgaaaatggccgaaggggct aagcttcagatgtgctacctactccatcatctctgtgacatccagttgcgacatcgtgtt gagagtataattgcattctcaaatggatttgttggtgatctacaggctgatcagttgagg cgttatattgagataaagcaatctgatctcccgagtgctgtggctgcgaagaaaacgcgt gaattcagatgtcctccgcgtgaacagatgaatgccattctaagtttcaaagctctcgag gatgatgatattgaaaattgcccatgtggtgttgaattgcgggatgcactcaatgcattc catgctcaacttatgtacactgtatccctcaatgctcttcaggattcagaggcagaagat gctggggcagcggatactggaaagtccggaccactatcgaagatatttaactttatcaat acagttaaggagctagaagaggagccggtggaaaagggtgaaccagttaagaagactcct gaagaaatattccgaaaagtcctcattaagactatcgtgtcctgggcagaggaatcccaa attgagacaccgaagctcgtgagggagatgtttagcctcctggtgcgacagtatgatact gttggtgagctaattaaagctctggagaagacatatgtgatcaacagtaagacgaagaat gatgttgccggtatgtgggtgggtctcagtcagatacgtgcccttctaccggtacagatg agtgaggaggaagaaaaattaatgagaacgcgcctgtggaagttggtgaataatcacaca ttcttccaacatccagacttgattcgtattctaagggtgcacgagaatgtaatggccgtt atgatgaatacccttgggagaagggctcaagcgcaaagcgatgcaccagtacagagtgag ggtggtgaacaaccagttaaggagaaggatacatcccatgagatggttgttgcatgttgt cgtttcctctgctacttctgtcgcacaagtcgtcaaaatcagaaagcaatgtttgatcat tttgattttctcctggagaactccaatattctcctttcgcgaccaagtttgcgtggttca acaccacttgatgttgcatactccagcttaatggaaaacactgaattagctcttgcttta agagagcactacttggagaagattgctgtctacctatccaggtgtggtttgcaaagtaat tcagagctcgtggagaagggttatccggacttgggatgggatcccgttgagggtgaaaga tatttggacttcctccgtttctgcgtttgggtgaatggtgaaagtgttgaggagaatgca aacttagttattcgcctattgatccgtagacctgaatgccttggtccagctctacgtggg gaaggtgaaggtcttctcagggctataattgatgcaaataaaatgtccgagaggattgct gatcgtcgtaagctgcaagatgaggcagaaggaacaatgtctggcttatcattcaaccat cctctacctgaaagtgatgacgatgaagattacattgatactggcgctgccatattatgc ttctactgcacccttgttgatctccttggacgctgtgctccggattcttctgtaattgca caggggaagaatgaatcgcttagggctagggccatcttgcgatcacttgtaccactggaa gatcttcaaggtgttctcagtctaaagtttacgctacaaaatccagctcctggtgaagag aaacctaaatcagatatgccttctgggcttattcctggacacaaacagagtatcgtcatg ttcttggaacgtgtctacggcattgaaacccaggaattattctacaaactactcgaggaa gccttcctgcctgatcttcgtgctgccacaatgctcgatcggaatgatggctctgaaagc gatatggctctttcaatgaatcgctacattggaaattcaattctacctttacttattcaa cattctaaattctacaatgaagcagaaaactacgcaagtcttcttgatgctacacttcac acagtttatcgcctttcgaagaatcgaatgcttacaaagggacaacgtgaagctgtttct gattttcttgttgccctcacagcacaaatgcaaccatctatgctcctcaagttattacgt aagctcactgttgatgtgtctcgcctttcggagtacacaactgtggcacttcgccttcta acactgcactatgatcggtgtgccaagtactatgggtcaagtggagggcagggtgcttat gggtcttcttctgatgaggaaaaaagactcacaatgcttctgttctcaaatatctttgac tccttgagcaatatggattatgatcctgagctgtttggtaaggcgctaccatgcctaatt gccattgggtgtgctctaccgcctgactatagtttatcaaagaataccgatgaggatttc tatgggaaacccgcttcaacatcggctccagatcagccacaatacaacccacagccaatc aatacgagtgccgtagtacttgacaatgatctgaattccattgtacagaaattcagtgag cactaccacgatgcttgggcgagtcggaaacttgaggctggatggtcatatggtgagcaa tggtcagacagccaaaagtctcatcctcgcctaaagccctacaatatgttgactgactat gagcgtgaacggtataaggaaccagttagggaggctctcaaagcactccttgcactagga tggactgttgaacatgccgaaggagatgttccactatcgcatcgtggttcaacaaggaga acatcaaaacctaatcttgaatttcagggtgactcatcatcaccatttaattacaatcct caaccaattgatatgactaacttaacgctaagtcgtgaaatgcaaaatatggcagagaga cttgcagagaattctcacgatatctgggcaaagaagaagcgtgaagagttgaatacatgt ggtggggcaattcattcacaacttgtaccatatgatttactaacggacaaggagaagcgc aaggatcgagagagatctcaggaattcctcaaatatatgcaatatcagggatacaagttg cacaaaccatctcgtggtttgtccgttgatggagaacaggctggtggtggtccagctatt gaactcagatttgcctactcgcttctggaaaagttaattcaatacttggacagagctaca atcaacatgaaactactgaaaccatcaacaactttcagtcgtaggaattccttcaagaca agtagcagagatattaaattcttttcaaaagttgttctacctttgatggaaaaatacttt tctactcatcgaaactactttatagccgttgcaacggcaaccaataatgttggagcagca tctctcaaagagaaagaaatggtagctgccctgttctgcaagttagcgagcttgttgcgc tatcgattggcagcttttggtccagatgttcgcatcacagtccgatgccttcaagtcttg gttaagggtattgatgcgaagtctttggtgaagaattgtcccgaatttattcgtacatca atgctgacattcttcaataacaccgcagacgatcttggacaaaccattgttaatttgcaa gaaggaagatatagtcacttgcgaggaacacacttgaagacatcaacatctctagcttat gtgaatacggtgatcttacccgttttaactgcaatgtttgatcacttatctgcctgtgaa tatggatcagatctactattggatgaaattcaagttgcttcctacaagattttagcatca ctgtatactttgggaacagatgctagccttactcatgataggaagtacctaaaaacggaa attgaacgacataaaccaagtctcggatcgtgtttaggagctttcagttcaacgttccca gttgcattcttagagcctcatctcaataagcacaatcaattttctctactcaatcgaatt gcagaccattctttagaagctcaagatataatggtgaagatggaggcttctatgcccaat cttgaagcaattcttcaagaagttgatcaatttgttgaatctgacaagacatacaatgat gctcaacatattattgatgttatactgccacttctctgcgcttacctacctttctggtgg gctcaaggacctgacaatcttacaccaactacagggaatcacgtgactatggtaacggca gatcatatgaatcagctacttaagaatgtcctgaagatgattaagaaaaatattgggaat gacaattccccatggatgacgaggattgcagcctatacacagcagatcattattaatagc tcggaagaattgctaaaggatcccttcttaccgctagctgaacgtgtacgtaaacgtacc gataatatgttccacaaggaagaaagtcttcggggttttataaaatccgcaacggatgat acatcgcaagttgaagcacaaattcaggaagattggcaacttcttgtacgagatatttac tctttttacccgttacttataaaatacgtggatttgcagaggaatcactggctaaagaat aacatcccggaagctgaggagttgtacaatcacgtagcggagattttcaatatttggtcc aagagtcagtacttcctgaaggaggaacaaaatttcatatcagccaatgaaattgataat atggcactcatcatgccaacggcaacgagacgaacgcaggttatttctgaggggcaacag aatactggggggaagataaagaagaaaaagaaggatcgaagtaagaaacgtgacaaggat aaggaggttcaggcaagcttaatggttgcctgcttgaagcgtctcctcccggttggcttg aatttgtttgccgggcgtgagcaagaattggtgcagcattgcaaggatcggtatttgaag aaaatgcaagagtacgatgtaattgagtttgctcgtacgcagctaacactaccggataaa ctcgatccagctgatgaaatgtcttggcagcactatttgtactcaaaacttgggaagaaa gaaacggaaattgatgaaattgtagaaaaatccaaagcttcagacgataagaagcccgaa aataagattgatgatacagttgataggattgtagcaatggctaaagttctctttggacta catatggcaaatcgcccaaagcagcgatctgataaatggcaacgtattgtgtcactggcc agaagaaaatccgcccttgcttgccttaaagctaaacctttgtataagctgagcagacac cgggcttgtaatatttttgcacgaacctaccatgagctatggctacaggatgaaaatgct ggtcaagaaattatgattgaggatctaacgcaatcatttgaggatgctgagaaggcgaag aaggatgcagaggaggaagaaagcaagcccgatccactaactcaacttgttacaaccttc tgtcgtggtgccatgacagaacgcagtggggctcttcaggaggatgccctctacatgtct tatgcacaaattgccgcaaaatcatgcggagaagaagaagaggagggtggcgaagaagaa ggcggtggtgaagagggtgaatcaagtggggcaagtattcataaaaacacaatggaaacc cttatggagcaagaaatggagaagcagaagcttcttttccatcaagctagactttcaaat cgtggtgtagctgagatggttcttcttcatatttcggcatcaaagggtgtaccatcggaa atggtcatgaagacccttgaattgggaatagccattctccgcggtggtaacatcgacatt caaatgggaatgttaaatcatctcaaggagaaaaaggatgttggcttctttacgtccatt gctggtctaatgaattcctgtagtgtattggatttagatgcatttgagaggaacactaag gcagaaggtttgggagttggagctgaaggtgcagcaggagaaaaaaatatgcacgatgct gaatttacgtgtgccctctttagattcatccaattgacatgtgaagggcataatttagaa tggcaaaactaccttagaacccaggcaggtaatactacaacagtcaatgtggttatctgt actgtggactacctattgcgacttcaggaatcaattatggacttctattggcactattcc agcaaggaaattattgatcccgccgggaaagcaaacttcttcaaagcaattggggtagca agtcaagttttcaatacactcactgaggtcattcagggtccgtgtaccctcaatcagcag gcattagcacattcgagattgtgggatgccgttggtggtttcctctttctcttttcgcac atgcaagacaagttgtcgaagcattcaagtcaagtggatttgctgaaggagctactcaat ctgcagaaggacatgatcaccatgatgttgtccatgcttgagggaaatgttgtcaatggt accattggaaagcaaatggtggacacactcgtggagtcagcgtcgaatgttgaattgatc ctcaaatacttcgatatgttcctcaaactcaaggatctcacatcaacacccagtttccag gagattgatcccaatggtgatgggtggattaatccaaaagattttcaggataaaatggaa caacaaaagagctacacccctgaggaaattgaattcttattggcttgctgtgagacaaat catgacgggaaaattgattatattgactttgtcgatcgcttccatgacccagctaaagag attggttttaatttggctgttcttctgacaaatctatcggagcacatgcccaatgaacca aggcttgctcgattcctggaaaccgctggatctgttctgaattactttgaggcgttcctt ggtagaattgagattatgggtagttcaaagaggattgagagagtctactttgaaattaag gaatccaacattgagcaatgggaaaaaccgcaaattaaggaatcaaagagagctttcttc tattcaattgtaacagaaggtggtgacaaggagaagctggaggcatttgtgaatttctgc gaagatgccatctttgaaatgacccatgcttctgcactaatggcaactgatgagggtggt gcaagtgtccgaagggaagcatcattcagtacctacatcagcgaagaggaggaagagaaa gctgccaaggatccaatcaagagaacagtacaaggtttcaaagacggcttctggttcatt ttgcatttcttcagtgtttccaacataaagcaccaaatagctgttgcacaaacaaaatcc atcccggagctgtttgtgggattcttcaagatgattttctatgctttctactactcaggc tatggtgttgctcttattgtgaagtacttcctcaatgttttgatgtctctaatgcgtgga tcgggtactgaggaggctgaacccgaacccgtacctgaggcaacgggattaatgcgagca ctaccggcactaccgcaagaggagcccccggggacggtacaagcattcggattagatata agtaaggaagagaatgggcaatacaaattggcaccgcatgagtctcccgcagcaagtcca tcgtcatcaatggaggaaactggggagagtagtccagaggatgcagctgcagcaggtgaa catgctacggaagagggtcaagagccaccgattacccttgtagatctccttggtggtgag gcagctaagagagctgctcaggaacgttcggaagcacagaaacttcaagaagctgcaatg gcaaccattgaggcggaaagtaagaaatcctcagcagaacccaaagaaccggctgcagtt acgcaaattgacttctcacagtacacccacaagatagtgagctttctcgcacggaatttc tacaatctcaagtatgtggcactggtgttggcgttctgcatcaacttcatgctactcttc tacaaagtcacgacattcggggaagatgaaggtggttctggggaaggtgaacttgatatg gaattcggctcagggggttcgggatctggacttggggctctactggaaggtagtggtctc gatatggacggcgaagggggtgaagaggaagatccattggaatcggtgcatgttgatgaa gacttttactacatggaacatgtcctgcgaatagctgctttcctccatagtacagtctcc cttgcaatgttgattgcctactatcacctaaaggttcctttggctatttttaagcgtgaa aaggagattgcacgacgcctggaattcgatggactcttcatagctgagcaaccagaagat gatgatataaagtcgcattgggataaacttgttatatcagctaaatccttccccgtcaac tactgggataagtttgtgaagaagaaggtgcggcagaagtatagtgaaacgtatgatttt gattgcatatcgaatcttctggggatggagaagtcagcatttacggcacaagaagctgaa ggaggtggtctcgttcactacatcgtcaccattgattggcgctatcagatttggaaggcg ggtgtaacaataactgacaatgccttcttgtactccctttggtactttaccttctcaatc tttggtaatttcaacaatttcttcttcgctgctcacctattggatgttgccgttggcttc aagaccctgcgcacaatcttgcaatctgtcacccacaatggcaaacaattggtgctaacg gtgatgctgcttacgatcatcgtgtacatttacacggttattgccttcaatttcttccgc aaattctacgtgcaggaagaagatgaggaagtggacaagaagtgccacgatatgctcact tgtttcgtcttccatctgtacaagggtgtacgagctggtggtgggataggtgatgaaatt ggtgatccagatggtgatgactacgaagtctatcgcatcatcttcgacatcacattcttc ttctttgtcattgtcatccttctggccatcattcagggtctcattattgatgccttcggt gagctccgtgatcaattggagtcagttaaggagaatatggagtcaaattgcttcatatgt ggcatagggaaggattactttgacatagtaccgcatggcttcgatacgcacgtccagaag gaacacaatctagccaattacatgttcttccttatgcatctaattaataaacccgacacg gagtatacgggtcaggagacctacgtgtggaatatgtatcaacagagatgctgggacttc ttccccgttggtgattgtttcaggaagcaatatgaagaggaattgggtggtggtagtggt gggtaa

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