Lactococcus lactis subsp. cremoris MG1363: llmg_0361
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Entry
llmg_0361 CDS
T00475
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
llm
Lactococcus lactis subsp. cremoris MG1363
Pathway
llm00300
Lysine biosynthesis
llm00550
Peptidoglycan biosynthesis
llm01100
Metabolic pathways
llm01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
llm00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
llmg_0361 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
llmg_0361 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
llmg_0361 (murF)
Enzymes [BR:
llm01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
llmg_0361 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
CAL96966
UniProt:
A2RI73
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Position
348927..350249
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AA seq
440 aa
AA seq
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MKLTIHEIAQVVGAKNDWSQLADLSVNKIEFDSRLIEKGDIFLPLKGARYGHDFIEIAFD
NGAIISFSEKEVEQAHLLVDDNLAAFQTLAKYYLEKTKVPVIAVTGSNGKTTTKDMIAAV
LSKKYKTYKTQGNHNNEIGLPYTILHMPEDTEKLVLEMGMDHPGDIDFLSQLAQPELALI
TLIGEAHLEFMGSRENIAKGKMGITAGLHGELIAPADPIINAFIPENQKISRFGLPGEDL
FITKLIEHKERLTFETNFLDESITIPVPGKYNATNAMLAAYVGLHYGLTEAEINKALKEV
ELTRNRTEWKKSKNGADLLSDVYNANPTAMRLILETFQAIPKNENGRKIAVLADMLELGP
TAAQLHKEVLKSIDFTKIDKVYLYGEMMKNLADISTDKPVSYFTDLDLLTESLSADLKPA
DQVLFKGSNIMKLSEVVEKL
NT seq
1323 nt
NT seq
+upstream
nt +downstream
nt
atgaaactcacaattcacgaaatcgctcaagtcgttggcgcaaaaaatgattggtcgcaa
ctggcagatttgtcagtaaataaaattgaatttgacagccgtttaattgaaaaaggagat
atctttttgccactcaaaggggcacgatatggtcatgatttcatcgagattgcttttgac
aatggagcaataattagcttttcagaaaaagaagttgaacaagctcatcttttggttgat
gataatctagcagctttccaaacattagcaaaatattatctggaaaaaacaaaagttcca
gttattgcggtgacaggctcaaatggtaaaacaaccaccaaagatatgattgctgctgtt
ttatctaaaaaatataaaacctataaaacacaaggaaatcataataacgaaattggattg
ccttacacaattttacacatgccagaggatactgaaaaattagtattagaaatgggaatg
gaccaccctggcgatattgattttctctcacaactagctcaacctgaactagctcttatt
accttaattggtgaagctcatcttgaatttatgggtagtcgtgaaaatattgcaaaaggt
aaaatgggtattactgctggtctacatggtgaattaattgcccctgctgacccaattatt
aatgcttttattccagaaaatcaaaaaatcagtcgttttggtttgcccggtgaagattta
ttcattacaaaattaattgagcacaaagaaagattgacttttgaaactaattttttagat
gaatcaataacgattccagttcctggtaaatataatgcaacgaatgctatgttagctgct
tatgttggcttacattatggattgacagaagctgaaatcaacaaagctttgaaagaagtt
gaactgaccagaaatcggacagagtggaaaaaatctaaaaatggagctgaccttttaagc
gacgtctataatgccaatccaacagctatgcgcctgattttggaaactttccaagccatt
cctaaaaatgaaaatggtcgaaaaatcgcagttcttgctgacatgttagaactcggacca
acagctgctcaacttcataaagaggtgctgaaatcgattgatttcacaaaaattgataaa
gtctatctttatggcgaaatgatgaaaaatttggcagatatttcgactgataaacctgtc
agctattttacagatttggatttactgacagaaagtctgtcagcagatttgaaaccagca
gaccaagttttattcaagggttcaaacatcatgaaactttcagaagttgttgaaaaatta
taa
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