Lactococcus lactis subsp. lactis IO-1: lilo_0309
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Entry
lilo_0309 CDS
T02485
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
lls
Lactococcus lactis subsp. lactis IO-1
Pathway
lls00300
Lysine biosynthesis
lls00550
Peptidoglycan biosynthesis
lls01100
Metabolic pathways
lls01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
lls00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
lilo_0309 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
lilo_0309 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
lilo_0309 (murF)
Enzymes [BR:
lls01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
lilo_0309 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF6585
Motif
Other DBs
NCBI-ProteinID:
BAL50310
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Position
327901..329223
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AA seq
440 aa
AA seq
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MKLTIHEIAQVVGAKNDWSQLADLSVNKIEFDSRLIEKGDIFLPLKGARDGHDFIEIAFD
NGAIISFSEKEVEQAHLLVDDNLLAFQKLAKYYLEKTKVPVIAVTGSNGKTTTKDMIAAV
LSKKFKTYKTQGNHNNEIGLPYTILHMPDDTEKLVLEMGMDHPGDIDFLSELAKPELAVI
TLIGEAHLEHMGSRENIAKGKMGITAGLHGELIAPADPIINAFIPDNQKIIRFGLPGEDL
FITKLVEHKEKLTFETNFLDESITIPVPGKYNATNAMLAAYVGLHYGLSEVEIKKALKEV
ELTRNRTEWKKAKNGADLLSDVYNANPTAMRLILETFQAIPKNENGRKIAVLADMLELGP
SAAQLHKDILKSIDFNKIDKVYLYGEMMKNLAEISTDKAVSYFTDLDLLTESLSADLKPT
DQVLFKGSNSMKLSEVVEKL
NT seq
1323 nt
NT seq
+upstream
nt +downstream
nt
atgaaactcacaattcacgaaatcgcccaagtcgttggcgcaaaaaatgattggtcgcaa
ctggcagatttgtcagtcaataaaattgaatttgacagccgtttgattgaaaaaggggat
atctttttgccacttaagggggcacgagatggtcatgatttcatcgaaatcgcttttgat
aatggagcaataatcagcttttcagaaaaagaagtcgaacaagctcatctcttggttgac
gataatctgcttgctttccaaaaattagcaaaatattatcttgaaaagacaaaagttcca
gtcattgcggtgacaggttcaaatggaaaaacaacaaccaaagacatgattgctgctgtt
ttgtctaagaaatttaaaacatacaaaacacaaggaaatcacaataatgaaatcggctta
ccctacaccattttacatatgccggacgatactgaaaaattagttttggaaatgggaatg
gatcaccctggtgatattgattttttatcagaacttgctaagcctgaacttgctgtcatt
accttaattggtgaagcacatcttgaacatatgggaagtcgcgaaaatattgctaaaggg
aaaatggggattacggctggtttgcatggtgagcttattgcccctgctgacccaattatt
aatgcttttatcccagacaatcaaaaaattattcgctttggtttgcccggtgaagattta
tttattacaaaattagtcgaacacaaagaaaaattaacttttgaaactaattttttagat
gaatcaattactattccagttcctggtaaatataacgcgacgaatgctatgttagctgct
tatgttggcttacattatggactttcagaagtcgaaattaaaaaagctttgaaagaagta
gagctgaccagaaatcggacagagtggaaaaaagccaaaaatggtgcagaccttttgagt
gatgtttataatgccaatccgacagcaatgcgtttgattttggaaactttccaagccatt
cctaaaaatgagaatggtcgaaagattgcagttcttgctgatatgttagaacttggaccc
agtgcagcccaactccataaagatatattgaaatctattgatttcaataaaattgataaa
gtctatctttatggtgaaatgatgaaaaacttggcagaaatttcgactgacaaagcggtc
agctattttacagatttagatttactgacagaaagtctgtcagcagatttgaaaccaact
gaccaagtgttattcaaaggttcaaatagcatgaaactttcagaggttgttgaaaaatta
taa
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