Lutra lutra (Eurasian river otter): 125080939
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Entry
125080939 CDS
T08100
Name
(RefSeq) hepatocyte growth factor receptor isoform X1
KO
K05099
proto-oncogene tyrosine-protein kinase Met [EC:
2.7.10.1
]
Organism
llv
Lutra lutra (Eurasian river otter)
Pathway
llv01521
EGFR tyrosine kinase inhibitor resistance
llv04010
MAPK signaling pathway
llv04014
Ras signaling pathway
llv04015
Rap1 signaling pathway
llv04020
Calcium signaling pathway
llv04151
PI3K-Akt signaling pathway
llv04360
Axon guidance
llv04510
Focal adhesion
llv04520
Adherens junction
llv05100
Bacterial invasion of epithelial cells
llv05144
Malaria
llv05200
Pathways in cancer
llv05202
Transcriptional misregulation in cancer
llv05205
Proteoglycans in cancer
llv05206
MicroRNAs in cancer
llv05208
Chemical carcinogenesis - reactive oxygen species
llv05211
Renal cell carcinoma
llv05218
Melanoma
llv05223
Non-small cell lung cancer
llv05225
Hepatocellular carcinoma
llv05226
Gastric cancer
llv05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
llv00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
125080939
04014 Ras signaling pathway
125080939
04015 Rap1 signaling pathway
125080939
04020 Calcium signaling pathway
125080939
04151 PI3K-Akt signaling pathway
125080939
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
125080939
04520 Adherens junction
125080939
09150 Organismal Systems
09158 Development and regeneration
04360 Axon guidance
125080939
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
125080939
05202 Transcriptional misregulation in cancer
125080939
05206 MicroRNAs in cancer
125080939
05205 Proteoglycans in cancer
125080939
05208 Chemical carcinogenesis - reactive oxygen species
125080939
05230 Central carbon metabolism in cancer
125080939
09162 Cancer: specific types
05225 Hepatocellular carcinoma
125080939
05226 Gastric cancer
125080939
05218 Melanoma
125080939
05211 Renal cell carcinoma
125080939
05223 Non-small cell lung cancer
125080939
09171 Infectious disease: bacterial
05100 Bacterial invasion of epithelial cells
125080939
09174 Infectious disease: parasitic
05144 Malaria
125080939
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
125080939
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
llv01001
]
125080939
Enzymes [BR:
llv01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
125080939
Protein kinases [BR:
llv01001
]
Receptor tyrosine kinases (RTK)
MET family
125080939
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
TIG
Pkinase
Sema
PSI
Kinase-like
Pkinase_fungal
Linker_histone
PepSY_TM
Motif
Other DBs
NCBI-GeneID:
125080939
NCBI-ProteinID:
XP_047551128
LinkDB
All DBs
Position
11:75281006..75396928
Genome browser
AA seq
1382 aa
AA seq
DB search
MRAPAVLAPGILVLLFTLVQKSCGECKEALVKSEMNVNMKYQLPNFTAETPIQNVVLHKH
HIYLGAVNYIYVLNDKDLQKVAEYKTGPVLEHPDCSPCQDCSHKANLSGAVWKDNINMAL
LIDIYYDDQLISCGSVQRGTCQRHVLPHSNTADIQSEVHCMYSPQADEEPGQCPDCVVSA
LGTKVLISEKTRFINFFVGNTINSSYHPDHSLHSISVRRLKETQDGFKFLTDQSYIDVLP
EFRDSYPIKYVHAFESNHFIYFLTVQRETLDAQTFHTRIIRFCSVDSGLHSYMEMPLECI
LTEKRRKRSTREEVFNILQAAYVSKPGAHLAKQIGANLNDDILYGVFARSQPDSAEPMNR
SAVCAFPIKYVNEFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEVRSDEYRTE
FTTALQRVDLFMGQFNQVLLTSISTFIKGELTIANLGTSEGRFMQVVVSRSGSSTPHVNF
RLDSHPVSPEAIVEHPLNQNGYTLVVTGKKITKIPLNGLGCDHFQSCSQCLSAPPFVQCG
WCHDKCVQLEECPTGTWTQEICLPTIYEVFPTSAPLEGGTMLTICGWDFGFRRNNKFDLK
KTKVLLGNESCTLTLSESTTNMLKCTVGPAVNEHFNISIIIANGRGTAQYSKFSYVDPII
TSISPSYGPKTGGTLLTLNGKYLNSGNSRHISIGGKTCTLKSVSDSILECYTPAQTTPTE
FPIKLKIDLANREMNSFSYQEDPIVYAIHPTKSFISGGSTITAIGKNLHSVSVLRMGINV
HEARRNFTVACQHRSNSEIICCTTPSLQQLSLQLPLKTKAFFMLDGIHSKYFDLIYVHNP
VFKPFEKPVMISIGNENVLEIKGNDIDPEAVKGEVLKVGNKSCETIYSDSEAVLCKVPND
LLKLNNELNIEWKQAVSSTILGKVIVQPDQNFTGLIVGVISISLIVLLLLGLFLWLKRRK
QIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNG
SCRQVQYPLTDLSPMLTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVH
FNEVIGRGHFGCVYHGTLLDNDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV
LSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKK
FVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQK
FTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKC
WHPKAELRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSQDNIDGEG
DT
NT seq
4149 nt
NT seq
+upstream
nt +downstream
nt
atgagggcccctgctgtgcttgcacctggcatccttgtacttctgtttaccttggtgcag
aagagctgtggggagtgcaaagaggcactagtaaagtctgagatgaatgtgaacatgaag
taccagcttcccaactttactgcagaaacacccatccagaatgttgttttacacaagcat
catatttacctcggtgcagttaactatatttacgttttaaatgacaaagaccttcagaag
gttgctgagtacaagactgggcccgtgctggaacacccagattgttccccatgtcaggac
tgcagccacaaagccaatttatcaggcgctgtttggaaagataacatcaacatggctcta
cttattgacatatactatgatgaccagctcattagttgtggcagtgtccagagagggacc
tgccagcgacatgtccttccacatagcaatactgctgatatacagtcggaagtccattgc
atgtactccccacaggcagatgaagagcctggccaatgccctgactgtgtggtgagtgcc
ctgggaaccaaagtcctgatatctgaaaagactcggttcatcaacttcttcgtgggcaat
accataaattcctcgtaccatccagatcattcattgcattcaatatcagtgagaaggcta
aaggaaacgcaagatggtttcaagtttttgacagaccaatcttatattgatgttctacct
gagttcagagattcctaccctattaaatatgtccatgcctttgaaagcaatcattttatt
tactttttgaccgtccaacgagaaactctagatgctcaaacttttcacacaagaataatc
aggttctgttctgtagactctggattgcattcctacatggaaatgcctctggagtgtatt
ctcacagaaaaaagaaggaagagatccacaagggaagaagtctttaatattctccaagct
gcatatgtcagtaagcctggggcccacctcgctaagcaaataggtgccaacctgaatgat
gacattctctatggagtgtttgcacgaagccagccagattcagctgaaccaatgaatcgc
tctgctgtctgtgcattccctatcaaatatgtcaatgaattcttcaacaagatcgtcaac
aaaaacaacgtgagatgtcttcaacatttttatggacccaaccacgaacactgctttaat
aggacacttttgagaaattcatccggctgtgaagtgcgcagtgatgaatatcgaacggag
tttaccacagctttgcagcgtgttgacttattcatgggccaattcaaccaagtcctctta
acatctatatctaccttcattaaaggagaactcaccattgctaatcttgggacgtcagag
ggtcgcttcatgcaggttgtggtttctcgatcaggatcatcaacccctcatgtgaatttt
cgcctagattcccaccctgtgtctcctgaagccattgtggagcacccattaaaccaaaat
ggctacacactggttgtcactgggaagaagattaccaagatcccactgaatggcttaggc
tgtgatcatttccagtcctgcagtcagtgtctctccgcgcctccctttgtgcagtgcggc
tggtgccacgataaatgtgtgcagttggaggaatgccccactggaacatggactcaggag
atctgtctgcctacaatctatgaggttttcccaactagcgcacccttggaaggagggaca
atgctgaccatatgtggctgggacttcggattcaggaggaataataaatttgatttaaag
aaaaccaaagttctccttggaaatgagagctgcaccttgaccttaagtgagagcacaaca
aatatgctgaaatgcacagttggtcctgcagtaaatgagcatttcaatatatccataatt
attgcaaatggtcgagggacagcacaatacagtaaattttcctatgtggatcctataata
acaagtatttctccaagttacggtcctaagactggtggcaccttgctaactttaaatgga
aagtacctgaacagtgggaattctagacacatttcaattggtggaaaaacatgtacttta
aaaagtgtgtcagatagtattctcgaatgttataccccagctcaaaccactccaactgag
tttcctattaaattgaaaattgacttagccaaccgagagatgaacagcttcagttaccaa
gaagaccccattgtctatgcaattcatccaaccaaatcttttattagtggtgggagcaca
ataacagctattggaaaaaacttgcattcagttagtgtcctgaggatgggaataaatgta
catgaagcaagaaggaactttacagtggcatgtcaacatcgctctaattcagagataatc
tgctgtacaactccttcactgcaacagctgagtctgcagctccctctgaaaaccaaagcc
tttttcatgttagatgggatccattccaaatactttgatctcatttatgtacataatcct
gtgtttaagccttttgaaaagccagtgatgatctcaataggcaatgaaaatgtactggaa
attaagggaaatgatattgaccctgaagcagttaaaggtgaagtgttaaaagttggaaat
aagagctgtgagaccatatactcagattctgaagctgttttatgcaaggtccccaatgac
ctgctgaagttgaacaacgagctaaatatagagtggaagcaagcagtttcttcaaccatc
cttggaaaagtaattgttcaaccagatcagaatttcacaggattgattgttggtgttatc
tcaatatcattaatagtcttattattacttgggcttttcctgtggctgaaaaggagaaag
caaattaaagatctgggcagtgaattagttcgctatgatgcaagagtacacactcctcat
ttggataggcttgtaagtgcccgaagtgtaagcccaactacagaaatggtttcaaatgaa
tctgtagactaccgagctacttttccagaagatcagtttcctaactcatcccagaatgga
tcatgcagacaagtacagtatcctctgacggacctgtcccctatgcttactagtggggac
tctgatatatccagtccattactgcaaaatactgtccacattgacctcagtgctctaaat
ccagaactggtccaggcagtccagcacgtagtaattgggccgagtagcctgattgtgcat
ttcaatgaagtcataggaagaggacattttgggtgtgtataccacgggactttgttggac
aatgatgacaagaaaattcactgtgctgtgaaatccttgaatcgaatcactgacataggc
gaagtttcccagtttctgactgagggaatcatcatgaaagactttagtcatccaaatgtt
ctttcactcttgggaatctgccttcgaagtgaggggtctccactggtggtcctaccatac
atgaaacatggagatcttcgaaatttcattagaaatgaaactcataacccaactgtaaaa
gatcttattggctttggtcttcaagtagccaaaggcatgaaatatcttgcaagcaaaaag
tttgtccacagagacttggctgcaagaaactgtatgctggatgaaaaattcactgtcaag
gttgctgattttggccttgccagagacatgtatgataaagaatactatagcgtacacaac
aaaacaggtgccaagctgcccgtgaagtggatggctttagaaagtctgcaaactcagaag
tttaccaccaagtcagatgtgtggtcctttggcgtgctcctctgggaactgatgacaaga
ggagcaccaccttatcctgatgtcaatacctttgatataacagtttacttgttgcaaggc
agaaggctcctacaacccgaatactgcccagatcccttatatgaagtgatgctcaaatgc
tggcaccctaaagctgagctgcgcccatctttttctgaactggtctccaggatatcagca
atattctctactttcattggggagcactacgtccatgtgaacgctacctatgtgaatgtc
aaatgtgttgctccatacccttccctgttgtcttcacaagataacattgatggcgagggg
gacacatga
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integrated database retrieval system