Lutra lutra (Eurasian river otter): 125082008
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Entry
125082008 CDS
T08100
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 2
KO
K05853
P-type Ca2+ transporter type 2A [EC:
7.2.2.10
]
Organism
llv
Lutra lutra (Eurasian river otter)
Pathway
llv04020
Calcium signaling pathway
llv04022
cGMP-PKG signaling pathway
llv04024
cAMP signaling pathway
llv04148
Efferocytosis
llv04260
Cardiac muscle contraction
llv04261
Adrenergic signaling in cardiomyocytes
llv04380
Osteoclast differentiation
llv04919
Thyroid hormone signaling pathway
llv04972
Pancreatic secretion
llv05010
Alzheimer disease
llv05017
Spinocerebellar ataxia
llv05022
Pathways of neurodegeneration - multiple diseases
llv05410
Hypertrophic cardiomyopathy
llv05412
Arrhythmogenic right ventricular cardiomyopathy
llv05414
Dilated cardiomyopathy
llv05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
llv00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
125082008
04024 cAMP signaling pathway
125082008
04022 cGMP-PKG signaling pathway
125082008
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
125082008
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
125082008
09153 Circulatory system
04260 Cardiac muscle contraction
125082008
04261 Adrenergic signaling in cardiomyocytes
125082008
09154 Digestive system
04972 Pancreatic secretion
125082008
09158 Development and regeneration
04380 Osteoclast differentiation
125082008
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
125082008
05017 Spinocerebellar ataxia
125082008
05022 Pathways of neurodegeneration - multiple diseases
125082008
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
125082008
05412 Arrhythmogenic right ventricular cardiomyopathy
125082008
05414 Dilated cardiomyopathy
125082008
05415 Diabetic cardiomyopathy
125082008
Enzymes [BR:
llv01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.10 P-type Ca2+ transporter
125082008
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1-E2_ATPase
Cation_ATPase_C
Cation_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
HAD
Motif
Other DBs
NCBI-GeneID:
125082008
NCBI-ProteinID:
XP_047553027
LinkDB
All DBs
Position
12:85573592..85636153
Genome browser
AA seq
997 aa
AA seq
DB search
MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKEKWGSNELPAEEGKTLLELVIEQFEDL
LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK
EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL
TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV
ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCRMFILDKVEGDSCSLNEFTITGSTYAPIGEVHKDDKPVKCHQYDGLVELATICALC
NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK
KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTPGV
KQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMNLEDSANFIKYETNLTFVGCVGMLD
PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDEL
NPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKSEIGIAMG
SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL
GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG
CYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKDDNPDFEGVDCAIFESPYPMTMAL
SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP
LNLTQWLMVLKISLPVILMDETLKFVARNYLEPAILE
NT seq
2994 nt
NT seq
+upstream
nt +downstream
nt
atggagaacgcgcacacaaagacggtggaggaggtgctgggccacttcggcgtcaacgag
agcacggggctgagcctggagcaggtcaagaagctcaaggagaaatggggttccaacgag
ttaccggctgaagaaggaaaaaccttgctggaacttgtgattgagcagtttgaagactta
ctagttagaattttattgctggcagcttgtatatcttttgttttggcttggtttgaagaa
ggtgaagaaacaataacagcctttgtagaaccctttgtaattttacttatattagtagcc
aatgcaattgtgggtgtgtggcaggaaagaaatgctgagaatgcaatcgaagcccttaag
gaatatgagcctgaaatgggcaaagtataccgacaggacagaaagagtgtccagcggatt
aaagctaaagacatagttcctggtgatattgtagaaattgctgttggtgacaaagttcct
gctgatataagattaacttccatcaaatctactactctaagagttgaccagtctattctc
acaggcgagtctgtgtcggtcatcaagcacacggaccccgtcccggacccgcgggccgtc
aaccaagataagaagaacatgctcttttctggtacaaacattgctgctggcaaagccatg
ggagtggtggtggcaactggagtgaacacagaaattggcaagatccgggatgaaatggtg
gcaacagagcaggagagaaccccgctccagcagaaactagatgagtttggggaacagctt
tccaaagtcatctccctgatttgcattgctgtctggatcataaacattgggcacttcaac
gacccagttcatggaggctcctggatcaggggtgctatttactacttcaaaattgcggtg
gctctggctgtggcagccattcctgaaggtctgcctgctgtcatcaccacctgcctggct
cttggaactcgcagaatggcaaagaaaaatgccattgttcgaagcctcccttctgtagaa
acccttggttgtacttctgttatctgctcggacaagactggtacgctgacaacgaaccag
atgtctgtgtgcaggatgttcattctggacaaagttgaaggtgatagctgttcccttaat
gagtttaccattactggatcaacttatgcacctattggagaagtgcataaagacgataag
ccggttaagtgtcatcagtatgacggtcttgtggaactggcaacaatttgtgctctttgt
aacgattctgccttggattacaatgaggcaaagggtgtgtatgaaaaagttggagaagct
acagagactgctctcacttgcctagtggagaagatgaatgtatttgataccgaattgaag
ggtctctctaaaatagagcgagcaaatgcctgcaactcggtcatcaagcagttgatgaaa
aaggaatttactctggagttttcacgtgataggaaatcgatgtcagtttattgtacacca
aacaaaccaagccggacatcgatgagcaaaatgtttgtgaagggtgctcccgaaggtgtc
atcgacaggtgcacccacattcgagttggaagtacgaaagttcctatgaccccgggagtc
aaacagaagatcatgtctgtcattcgggaatggggcagtggcagcgacacactgcggtgc
ctggctctggccactcatgacaacccactgagaagagaagaaatgaaccttgaggactct
gccaactttattaaatacgagaccaatctgactttcgttggctgtgtgggcatgctggac
cctccaagaattgaagtggcctcttctgtgaagctgtgccggcaagcaggcatccgggtc
atcatgatcacgggggacaacaagggcactgcagtggccatctgtcggcgcattggcatc
ttcgggcaggacgaggatgtgacttcaaaggcttttacgggtcgggagtttgatgagctc
aatccttcagcccagagagatgcctgtttgaatgctcgctgttttgctcgagttgaacct
tcccacaagtcaaaaattgtagaatttcttcagtcttttgatgagattacagctatgact
ggggacggcgtgaatgatgctcccgccctgaagaaatctgagatcggcattgccatgggc
tctggcacggcagtggctaaaacggcctcagagatggtgctggccgacgacaacttttcc
accatcgtggctgcggtggaggaggggcgcgccatctacaacaacatgaagcagttcatc
cgctatctcatctcctcgaatgtgggggaagtggtctgtatcttcctgacagcagccctt
ggctttcctgaggctttaattcctgtccagctgctctgggtcaatctggtgacagacggc
ctgcctgccactgccctggggttcaaccctcccgacctggacatcatgaacaaaccaccc
cggaacccgaaggaacccctgatcagtggatggctctttttccgttacctggccattggc
tgttacgttggcgcagctaccgtgggtgccgccgcgtggtggttcattgctgccgacgga
gggccaagggtgtccttctaccagctgagccacttcctacagtgtaaagatgacaacccg
gactttgaaggagtggattgtgcaatctttgagtccccatacccgatgacaatggcgctg
tctgttctagtaaccatagagatgtgtaacgccctcaacagcttgtccgaaaaccagtcc
ctgctgaggatgcccccctgggagaacatctggctcgtgggctccatctgcctgtccatg
tcgctccacttcctcatcctctacgtggaacctttgccacttattttccagatcacaccg
ctgaatctgacccagtggctgatggtgctgaaaatctccttgcctgtgattctgatggac
gagacactcaagtttgtggcccgcaactacctggaacctgcaatactggagtaa
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