Lutra lutra (Eurasian river otter): 125083176
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Entry
125083176 CDS
T08100
Name
(RefSeq) tyrosine-protein kinase ABL1 isoform X1
KO
K06619
abelson tyrosine-protein kinase 1 [EC:
2.7.10.2
]
Organism
llv
Lutra lutra (Eurasian river otter)
Pathway
llv04012
ErbB signaling pathway
llv04014
Ras signaling pathway
llv04110
Cell cycle
llv04360
Axon guidance
llv04722
Neurotrophin signaling pathway
llv05200
Pathways in cancer
llv05206
MicroRNAs in cancer
llv05208
Chemical carcinogenesis - reactive oxygen species
llv05220
Chronic myeloid leukemia
llv05416
Viral myocarditis
Brite
KEGG Orthology (KO) [BR:
llv00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
125083176
04014 Ras signaling pathway
125083176
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
125083176
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
125083176
09158 Development and regeneration
04360 Axon guidance
125083176
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
125083176
05206 MicroRNAs in cancer
125083176
05208 Chemical carcinogenesis - reactive oxygen species
125083176
09162 Cancer: specific types
05220 Chronic myeloid leukemia
125083176
09166 Cardiovascular disease
05416 Viral myocarditis
125083176
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
llv01001
]
125083176
Enzymes [BR:
llv01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
125083176
Protein kinases [BR:
llv01001
]
Non-receptor tyrosine kinases
ABL family
125083176
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
F_actin_bind
SH2
SH3_1
SH3_2
SH3_9
Haspin_kinase
Kinase-like
SH3_6
Motif
Other DBs
NCBI-GeneID:
125083176
NCBI-ProteinID:
XP_047555170
LinkDB
All DBs
Position
13:90337842..90474125
Genome browser
AA seq
1149 aa
AA seq
DB search
MGQQPGKVVGDQRRPSLPALHFIKGAGKKESSRHGGPHCNVFVEHEALQRPVASDFEPQG
LSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCE
AQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQR
SISLRYEGRVYHYRINTASDGKLYVSSESRFNALAELVHHHSTVADGLITTLHYPAPKRN
KPTIYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVE
EFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLL
YMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKF
PIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERP
EGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKKGVRGVAST
LLQAPELPTKTRTSRRAAEHKDPTEVPEMPHSRGPGETEPLDHEPPVSPLLPRKERGPQD
GGLNEDERLLPKDKKTNLFSALIKKKKKTAPAPPKRSSSFREMDGQPERKATSEEEGRET
SNGAPVLTPSDAAEPAKSPKPSSRAGVPNGAFRESGGAGFRSPHLWKKSSTLTSSRLAAS
EEESGSSSSKRFLRSCSASCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPA
LPRKRASENRSDQVTRGTVTPPPRLVKKTEDAADEVFRDAGESSPGSSPPSLTPKLLRRQ
VAGTPSSGLLHKDEVGKSGALGTLVAAEPVPATSRAGPGASGGAGKAPTEEPRARRHKPS
SESPGRDKGKLSKLKPVPPPPPPASAGKAGKPSQSLSQEAAGEAGAGGKAKAAAVVVDAV
NSDAVKPGPLGEGVKKPGLPSMPKPQSSKPAGTPTSPAPAPSASPSASSSLAGDQPASTA
FIPLISTRVSLRKTRQPPERIASGTITKGVVLDGTEALCLAISKNSEQMASHSAVLEAGK
DLYTFCVSYVDSIQQMRNKFAFREAINKLEHNLRELQICPATAGSGPAATQDFSKLLSSV
KEISDIVQR
NT seq
3450 nt
NT seq
+upstream
nt +downstream
nt
atggggcagcagcctggaaaagttgttggggaccagagaaggccaagtttgcctgccctg
cactttatcaaaggagcagggaagaaggagtcatcgaggcatgggggcccgcactgcaat
gtttttgtggaacacgaagcccttcagaggccagtagcatctgactttgagccccaaggt
ctcagcgaagcagctcgttggaactccaaggaaaaccttcttgctggccccagtgaaaac
gacccaaaccttttcgttgcactgtatgattttgtggccagtggggacaacaccctaagt
ataactaaaggtgagaagctccgggttttaggctacaatcacaatggggagtggtgtgaa
gcccaaaccaaaaatggccaagggtgggtcccaagcaactacatcacaccagtcaacagt
ctggagaaacattcctggtaccacgggcccgtgtcccgcaacgcagctgagtacctgctg
agcagcgggatcaacggcagcttcttggtccgggagagcgagagcagtcctggccagagg
tccatctcgctgagatacgaagggagggtgtaccactacagaatcaacactgcttccgat
ggcaagctctacgtctcctcagagagccgcttcaacgctttggctgagttggttcatcat
cactcgactgtggccgatgggctcatcaccactctccattacccggcccccaagcgcaac
aagcccaccatctacggcgtgtcccccaactacgacaagtgggagatggagcgcacggac
atcaccatgaagcacaagctgggcggaggccagtacggggaggtgtacgaaggtgtgtgg
aagaaatacagcctgacggtggccgtgaagaccttgaaggaggacaccatggaggtggag
gagttcttgaaagaagccgcagtgatgaaagagatcaagcaccccaatctggtgcagttg
ctcggggtctgcacccgggagcccccattctacataatcactgagttcatgacctacggg
aacctgctggattacctgagggagtgtaaccggcaggaggtgaacgccgtggtgctgctc
tacatggccacccagatctcgtcagccatggagtacctggagaagaagaacttcatccac
agagatcttgctgcccgaaactgcctggtaggggagaaccacttggtgaaggtagctgac
ttcggcctgagcaggttaatgaccggggatacctacacagcccatgccggggccaagttc
ccgatcaagtggacagcgccagaaagcctggcctacaacaagttctccatcaagtccgac
gtctgggcttttggagtattactttgggaaattgccacctacggcatgtcaccttaccca
ggaattgacctgtcccaagtgtatgagctgctggagaaggactatcgcatggagcgccca
gaaggctgcccagagaaggtctacgaactcatgcgagcatgttggcagtggaatccctcc
gaccggccatcctttgctgaaatccaccaagcctttgagacgatgttccaggaatccagc
atatcagatgaagtggaaaaggaactggggaagaaaggtgtgcgaggggttgcgagtact
ttgctgcaggccccggagctgcccaccaagaccagaacctccaggagagctgcagaacac
aaggaccccactgaggtgcctgagatgccccactccaggggcccgggagagaccgagcct
ctagaccacgagcctcctgtgtctccactactccctcgaaaagaacgaggtccccaggat
ggtggcctaaatgaagatgagcgccttctccccaaagacaaaaagaccaacttgttcagt
gccttgatcaagaagaagaagaaaacagccccggcccctccgaaacgcagcagctccttc
cgggagatggacggccagcccgagcgcaaggcgaccagcgaggaagagggccgagaaacc
agcaatggggcgccagtcctcacaccctcggacgcggccgagccagccaagtccccaaaa
cccagcagcagggctggtgtccccaacggagccttccgggaatcaggaggtgcaggcttc
cggtctccccacctgtggaaaaagtccagtacactgaccagcagccgcctagcagccagc
gaggaggagagtggcagcagctccagcaagcgcttcctcaggtcctgctctgcctcctgc
gtgccccacggggcgaaggacacagagtggaggtctgtcacactgccacgcgatctgcag
tccacggggaggcagttcgactcgtccacatttggagggcacaaaagcgagaagccagct
ctgcctcggaagcgggcaagtgagaacaggtccgaccaggtgaccagaggcacggtgact
cccccacccaggctggtgaaaaagactgaggacgcagcggatgaggtcttccgagacgcc
ggggagtccagcccaggctccagccctcccagtttgactccaaaactcctccgcaggcag
gtcgcggggactccttcctctggccttctccacaaggatgaggtcgggaagtctggtgcc
ttggggacacttgtcgcagctgagccagtgcccgccaccagcagagcagggccaggagca
tctgggggggccggcaaggcccccaccgaagagcccagagcgaggaggcacaagccctct
tccgagtccccagggagagacaaggggaagctgtccaagctcaagcctgtcccgccgccc
ccgccaccggcctccgctgggaaagccgggaagccctctcagagcctgagccaggaagca
gcgggggaggccggcgctggtgggaaagccaaagccgcggccgtggttgtggatgctgtg
aacagtgacgctgtcaagcccgggccactgggagaaggcgtcaaaaagcctgggcttccg
tccatgccaaagccacagtccagcaagccggcagggaccccaaccagcccagctcccgcc
ccctccgcctcgccatcagcatcttcttccctggccggagaccagccagcctccactgcc
ttcatcccgctcatatcgacccgtgtgtctcttcggaaaacccgccagcctccagagcgg
atcgccagtggcaccatcaccaagggcgtggtcctggacggcacggaggctctgtgcctg
gccatctccaagaactctgagcagatggccagccatagcgccgtgctggaagccggcaag
gacctctacacgttttgcgtgagctatgtggattccatccagcaaatgaggaacaagttc
gccttccgcgaggccatcaacaaactggagcataatctccgggagcttcagatctgcccg
gcgacagcaggcagcggcccggcggccactcaggacttcagcaaactcctcagctccgtg
aaagagatcagtgacatcgtacagaggtag
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