Lutra lutra (Eurasian river otter): 125083271
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Entry
125083271 CDS
T08100
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial-like isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
llv
Lutra lutra (Eurasian river otter)
Pathway
llv00790
Folate biosynthesis
llv01100
Metabolic pathways
llv01240
Biosynthesis of cofactors
llv01523
Antifolate resistance
llv04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
llv00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
125083271
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
125083271
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
125083271
Enzymes [BR:
llv01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
125083271
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
125083271
NCBI-ProteinID:
XP_047555423
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Position
13:88085052..88101235
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AA seq
589 aa
AA seq
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MSQARCHLRAALFLAAVSSRGATTGVTARRGLSAWPAPQEPGMEYQDAVRTLNTLQTNAG
YLEKVKRQRGDPQTQLDAMKLYLARSGLQVEDLDQLNIIHVTGTKGKGSTCAFTERILRS
YGLKTGFFSSPHLVQVRERIRINGQPISPELFTKHFWHLYHRLEETKDSSSCVSMPAYFR
FLTLMAFHIFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGISSLGIDHTSLLGDTVEAI
AWQKGGIFKRGVPAFTVLQPDSPLAVLRDRAQQISCPLYLCPPLEALEEGGPPLTLGLEG
EHQRSNAALALQLSRCWLQQKGHQGLGELKISRPSVLRQMPLAPVFQPTSHMRHGLRDTE
WLGRTQTLRRGPVTWYLDGAHTVSSVQACVRWFRQALHRSRRPSGGREVRVLLFNSTGNR
DSAALLKLLQPCQFDYAIFCPNLTEVSSASNADQQNFMVTLDQVLLRCLAHQQHWSHLDE
EPASPDLWSPTNPEPGDEPTSLLLASHPRHTHSTGSLVFSCISHALQWISQGRDPVFQPP
SPPPGLLAHPVAGSGAGVLREAAAIHVLVTGSLHLVGGVLKLLEPSLSQ
NT seq
1770 nt
NT seq
+upstream
nt +downstream
nt
atgtcgcaggcacgctgccacctgcgcgccgctctcttcctggcggcagtttcttcacgc
ggtgccacgaccggggtcacggcgcggcgagggttgagcgcgtggcccgcgccgcaggag
cccggcatggagtatcaggatgctgtgcgcacactgaacaccctgcagaccaatgctggc
tacctggagaaggtgaagcgccagcggggtgaccctcagacgcagctggacgcgatgaag
ctgtacttggcccggagtgggctgcaggtggaagacttggaccagctgaacatcattcac
gtcactgggaccaaggggaagggttccacttgtgccttcactgaacgtattctccgcagc
tatggcctgaagacaggattctttagctctccccacctggtgcaggtgcgggagcggatc
cgcatcaacgggcagcccataagccccgagctcttcaccaagcacttttggcacctctac
caccggctggaggagaccaaggacagcagcagctgtgtctccatgcctgcctacttccgc
ttcctcacactcatggccttccacatcttcctccaggagaaggtggacctggcggtggtg
gaagtgggcattggtggcgcttacgactgtaccaacatcatcaggaagcctgtggtgtgt
ggcatctcctctcttggcatcgaccacaccagccttctgggggacacagtggaggcgatc
gcatggcagaaagggggcatcttcaagcgtggcgttcctgccttcacggtgctccagcct
gacagtcccctggcagtgctgcgggaccgtgcccagcagatctcgtgtcctctctacctg
tgcccaccactcgaagccctggaggaaggcgggccgccgctgaccctgggcctggaggga
gagcaccagcggtccaacgccgccttggccttgcagctgtctcgctgctggctgcagcaa
aagggccaccagggcctcggggagctgaagatatctcggcccagcgtcttgcggcagatg
cctctggcacccgtgttccagcccacgtcccacatgcgacatgggcttcgggacactgag
tggctgggccggacgcagacactgcggcgcgggccggtcacctggtacctggacggcgcg
cacaccgtgagcagtgtgcaggcctgcgtgcgctggttccgccaggcgctgcaccgcagc
cggaggccgagcggaggccgtgaggtgcgcgtgttgcttttcaactccactgggaaccgg
gattccgcggccctgctgaagctgctgcagccctgtcagtttgactatgccattttctgc
cctaacctgacagaggtgtcatctgctagcaacgcagaccagcagaacttcatggtgacc
ctggaccaggtgttgctccgctgccttgcacatcaacagcactggagccacctggatgag
gagccggccagcccggacctctggagccccaccaacccggagcctggtgatgagcccacg
tccttgctgctggcttcccacccacgccacacccatagcaccggctccctcgtcttcagc
tgcatctcccatgccctgcagtggatcagccaaggccgggaccctgtctttcagccaccc
agtcccccgccaggcctccttgcccaccctgtggctggcagtggggctggtgtgctccga
gaggctgccgccatccatgtactggtcacaggcagcctgcacctggtgggcggcgtcctg
aagctgctggagccttccctgtcccagtag
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