KEGG   Lutra lutra (Eurasian river otter): 125085919
Entry
125085919         CDS       T08100                                 
Name
(RefSeq) sodium/potassium-transporting ATPase subunit alpha-2 isoform X1
  KO
K01539  sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
Organism
llv  Lutra lutra (Eurasian river otter)
Pathway
llv04022  cGMP-PKG signaling pathway
llv04024  cAMP signaling pathway
llv04260  Cardiac muscle contraction
llv04261  Adrenergic signaling in cardiomyocytes
llv04820  Cytoskeleton in muscle cells
llv04911  Insulin secretion
llv04918  Thyroid hormone synthesis
llv04919  Thyroid hormone signaling pathway
llv04925  Aldosterone synthesis and secretion
llv04960  Aldosterone-regulated sodium reabsorption
llv04961  Endocrine and other factor-regulated calcium reabsorption
llv04964  Proximal tubule bicarbonate reclamation
llv04970  Salivary secretion
llv04971  Gastric acid secretion
llv04972  Pancreatic secretion
llv04973  Carbohydrate digestion and absorption
llv04974  Protein digestion and absorption
llv04976  Bile secretion
llv04978  Mineral absorption
Brite
KEGG Orthology (KO) [BR:llv00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    125085919
   04022 cGMP-PKG signaling pathway
    125085919
 09140 Cellular Processes
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    125085919
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    125085919
   04918 Thyroid hormone synthesis
    125085919
   04919 Thyroid hormone signaling pathway
    125085919
   04925 Aldosterone synthesis and secretion
    125085919
  09153 Circulatory system
   04260 Cardiac muscle contraction
    125085919
   04261 Adrenergic signaling in cardiomyocytes
    125085919
  09154 Digestive system
   04970 Salivary secretion
    125085919
   04971 Gastric acid secretion
    125085919
   04972 Pancreatic secretion
    125085919
   04976 Bile secretion
    125085919
   04973 Carbohydrate digestion and absorption
    125085919
   04974 Protein digestion and absorption
    125085919
   04978 Mineral absorption
    125085919
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    125085919
   04961 Endocrine and other factor-regulated calcium reabsorption
    125085919
   04964 Proximal tubule bicarbonate reclamation
    125085919
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:llv04147]
    125085919
Enzymes [BR:llv01000]
 7. Translocases
  7.2  Catalysing the translocation of inorganic cations
   7.2.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.2.2.13  Na+/K+-exchanging ATPase
     125085919
Exosome [BR:llv04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   125085919
  Exosomal proteins of other body fluids (saliva and urine)
   125085919
  Exosomal proteins of colorectal cancer cells
   125085919
  Exosomal proteins of bladder cancer cells
   125085919
SSDB
Motif
Pfam: E1-E2_ATPase Cation_ATPase_C Cation_ATPase Cation_ATPase_N Hydrolase Hydrolase_3 Sigma70_r4 HAD
Other DBs
NCBI-GeneID: 125085919
NCBI-ProteinID: XP_047560806
LinkDB
Position
15:complement(65245772..65269140)
AA seq 1020 aa
MGRGAGREYSPAATTAENGGGKKKQKEKELDELRRMVAMDDHKLSLDELGRKYQVDLSKG
LTNQRAQDILARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAME
DEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVVREGEKMQINA
EEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNI
CFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFL
GVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLE
AVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALS
RIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPF
NSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYM
ELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAV
GKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPREAKAC
VVHGSDLKDMTSEQLDEVLKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSP
ALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSN
IPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPQTDK
LVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRSMNDLEDSYG
QEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETA
LAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY
NT seq 3063 nt   +upstreamnt  +downstreamnt
atgggccgtggggccggccgcgagtactcgcccgcagccaccaccgcggagaatgggggc
ggcaagaagaagcagaaggagaaggagcttgacgagctgagaaggatggtggccatggac
gaccacaagctgtccttggatgagctgggccgcaaataccaagtggacctatccaagggc
ctcaccaaccagcgggcccaggacattctggcccgggacggacccaacgccctcaccccg
cccccgacaacccccgagtgggtcaagttctgccgccagctcttcgggggtttctccatc
ttgctgtggatcggggccatcctctgcttcctggcctacggcatccaggccgccatggag
gacgaaccatccaacgacaacctctatctgggcgtggtgctggcagccgtggtcattgtc
accggctgcttctcctactatcaggaagccaagagctccaagatcatggattccttcaag
aacatggtgccacagcaagccctggtggtgcgggaaggagagaagatgcagatcaacgca
gaggaggtcgtggtgggggacctggtggaggtgaagggcggggaccgcgtacccgcggac
ctccggatcatctcttctcacggctgcaaggtggataactcatccctaacaggcgagtcc
gagccccagacccgctcccccgagttcacccatgagaaccccttggagacccgcaacatc
tgcttcttctccaccaactgcgtggaaggcacggccaggggcatcgtgatcgccacggga
gaccggacagtgatgggccgcatagccaccctggcctcgggcctggaggtggggcggacg
cccatcgccatggagatcgagcatttcatccagctgatcacgggggtggccgtgttcctg
ggggtctctttcttcgtgctctccctcatcctgggctacagctggctggaggctgtcatc
ttcctcatcggcatcatcgtggccaatgtgcctgaggggctgctggccactgtcaccgtg
tgtctgaccctgacagccaagcgcatggctcgtaagaactgcctggtgaagaacctggag
gccgtggagacgctcggctccacatccaccatctgctccgacaagacgggcaccctcacc
cagaaccgcatgaccgtcgcccacatgtggttcgacaaccagatccacgaagcggacacc
acggaagatcagtccggggccactttcgacaaacgatcccccacgtggacggcactgtct
cggattgccggcctctgcaaccgtgccgtcttcaaggccgggcaggagaacatctctgtg
tctaagcgggacacggctggtgatgcctccgagtcagccctgctcaagtgcatcgagctg
tcctgcggctccgtgcggaagatgagggacagaaaccccaaggtggcagagatccctttc
aattccaccaacaagtaccagctgtccatccacgagcgagaggacagcccccagagccac
gtgctggtgatgaagggggccccggagcgcatcctagaccgctgctccaccatcctggtg
cagggcaaggagatccctctggacaaggagatgcaggacgcctttcagaacgcctacatg
gagctgggcgggctgggggagcgcgtgctggggttttgtcagctgaatctgccttccggg
aagtttccgcggggcttcaagtttgacacggacgagctgaacttccccacggagaagctc
tgcttcgtggggctcatgtccatgatcgaccctccccgggctgccgtgccagacgccgtg
ggcaagtgccgcagcgcgggcatcaaggtgatcatggtgaccggggaccaccccatcaca
gccaaggccatcgccaaaggtgtgggcatcatatcagaaggcaacgagactgtggaggac
atcgcggcccggctcaacattcctgtcagccaggtcaaccccagagaagccaaggcgtgc
gtggtgcacggctccgacctgaaggacatgacatcggagcagctggacgaggtcctcaag
aaccacacagagatcgtgttcgcgcgcacgtccccgcagcagaagctcatcatcgtggag
ggttgccagcggcagggggccatcgtggcagtgaccggggacggcgtgaacgactccccc
gcactgaagaaggcggacatcggcatcgccatgggcatctcaggctccgacgtgtccaag
caggccgccgacatgatcctgctggacgacaactttgcctccatcgtcacgggcgtggag
gagggccgcctgatcttcgacaacctgaagaagtccatcgcctacaccctgaccagcaac
atccccgagatcacacccttcctgctgttcatcatcgccaacatccccctgccgctgggc
accgtcaccatcctctgcatcgacctgggcaccgacatggtccccgccatctccttggcc
tacgaggccgcggagagtgacatcatgaagcgacagccgaggaacccccagacggacaag
ctggtgaacgagagactcatcagcatggcctacggacagattgggatgatccaagccctg
ggtggctttttcacctacttcgtcatcctggcggagaacggtttcctgccctcgcggctg
ctgggaatccgtctggactgggacgaccggtccatgaacgacctggaggacagctatggg
caggagtggacctacgagcagcggaaggtggtggagttcacgtgccacacggccttcttt
gccagcatcgtggtcgtgcagtgggccgacctcatcatttgcaagacccggcgcaactca
gtcttccaacagggcatgaagaacaagattctgattttcgggctgctggaggagacggcg
ctggcggccttcctgtcctactgcccgggcatgggcgtagccctccgcatgtacccgctc
aaggtcacctggtggttctgcgccttcccctacagcctcctcatcttcatctatgatgag
gtccggaagctcatcctgagacggtaccctgggggctgggtggagaaggagacctactac
tga

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