Lutra lutra (Eurasian river otter): 125086044 Help Entry 125086044         CDS       T08100                                  Name (RefSeq) hemicentin-1 isoform X1   KO K17341   hemicentin Organism llv  Lutra lutra (Eurasian river otter) Brite KEGG Orthology (KO) [BR:llv00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04990 Domain-containing proteins not elsewhere classified [BR:llv04990]     125086044 Domain-containing proteins not elsewhere classified [BR:llv04990]  EGF-like domain-containing proteins   hEGF / cEGF domain-containing proteins    125086044 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  I-set Ig_3 Ig_2 ig V-set C2-set_2 TSP_1 EGF_CA VWA_4 G2F V-set_CD47 Ig_6 cEGF TSP1_spondin Receptor_2B4 Ig_C17orf99 GBD_Hemicentin TSP1_CFP_C FXa_inhibition EGF_3 TSP1_ADAMTS Fibulin_C EGF DRL_cat hEGF Motif Other DBs NCBI-GeneID:  125086044 NCBI-ProteinID:  XP_047561043 LinkDB All DBs Position 15:21439237..21916638 Genome browser AA seq 5635 aa AA seqDB search MISWDIVHTVFLFALLSSSQAQDASPQPDPGAEEIPEGASTLAFVFDVTGSMYDDLVQVI EGASKILETSLKRPKRPLFNFALVPFHDPEIGPVTITTDPKKFQYELRELYVQGGGDCPE MSIGAIKIALEISLPGSFIYVFTDARSKDYRLTHEVLQLIQQKQSQVVFVLTGDCDDRGH IGYKVYEEIASTSSGQVFHLDKKQVNEVLKWVEEAVQSSKVHLLSTDHLEQAVNTWKIPF DPSLKEVTVSLSGPSPGIEIRNPLGKLIKKGFGLNELLNIHNSAKVVNVKEPEAGMWTVK TSSSGRHSVRITGLSTIDFRAGFSRKPTLDFKKTVSRPVQGIPTYVLLNTSGISIPARVD RLELLSTSGSSLKTIPVKYYPDRKPYGVWNISDFIPPNEAFFLKVTGYDKDDYLFQRVSS VSFSSIIPDAPRVTMPKKTPGYYLQPGRIPCSVESLLPFTLSFVRNGVTLGVDQYLKESS SVNWEIEKVTLSDEGAYECIAVSSVGTGRAQTFFDVSEPPPVIQVPDNVTVPPGERAVLT CLVLSAVDYNLTWQRNDRDARQADPARMRILANLSLELRSVKFSDAGEYLCVVSNEGGSS AASVFLTVQEPPKVTVMPKNQSFTGGSEVSIRCSATGYPKPKITWTINDMFIMGSHRYRM TSEGNLFIKNAVPRDAGIYGCLASNAAGTDKQTSTLRYIEAPKLNVVQSELLVALGDTTV MECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAVNDAGR VAGKITLDVGSSPVFIQEPADVSVEIGSNVTLPCYVQGYPEPKIKWQRSDNMPIFSRPFS VSSISQLRTGALFISNIWANDKGTYICEAENQFGKIQSQTTITVTGLVAPLIGISPSVTS VIEGQQLTLPCALLAGNPIPERRWIKNSAMLVQNPYITVRSDGSLHIERVRLQDGGKYTC VASNVAGTFNKTTTVDVHVLPTIQHGQQVLSTIEGIPVTLPCKASGIPKPSIIWSKKGEL ISTSSAKFSTGADGSLYVVSPGGEESGEYVCTATNAAGYAKRKVQLTVYVRPRVFGDQRG LSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKIIET RVSDSGMYLCVATNIAGNVTQSVKLNVHVPPKIQRGPKLMKVQAGQRVDILCNAQGTPLP VITWLKGGSAALVDGARLVSNSDGTLSIDPALLSDAGVYTCVATNMAGSDETEITLHVQE PPTLEDLEPPYNTPFQERVASERIAFPCPAKGTPKPTIKWIWNGRELTGREPGISILEDG TLLVIASVTPSDNGEYICVAVNEAGTTEKKYNLKVHVPPVIKDKEQITNVSVLVNQLTNL FCEVEGTPSPIVMWYKDEVQVTESSTIQIVNNGKILKLFRVAPEDAGSYSCKAVNVAGTS QKYFNVEVLVPPTIIGAGSPNEVSVVLNRDITLECQVKGTPFPVIHWFKDGKPLFLEDPN TELLDRGQVLHLKNARRSDKGRYQCAASSGAGKQVKDIKLTVYIPPSIKGGNVTTEISAL INSMIKLECETRGLPMPAISWYKDGQPVISSSQALYIDKGQFLHIPRAQVSDSATYTCHA TNVAGTAEKSFHVDVYVPPVIEGDLAVPLNKQVVIAHSLTLECKATGNPPPVLTWLKDGV PVKPSDNIHTEAGGKKLEIRRVLEADRGQYVCVATSVAGEKEIKYEVDVLVPPAIEGGDE TSYFIVMINNLLELDCQVTGSPTPTIMWLKDGQIIDERDGFKILLNGRKLVITQAQVSDT GLYRCVATNIAGDHKKEFEVTIHVPPTIKSSGLSERAIVKYKPITLQCIANGIPNPSITW LKDGQPINTAQGNLKIQSSGRVLQIAKALMEDAGRYTCVATNAAGETQHHLQLHVHEPPS LEDAGKMLNETVVLNNPIQLECKAAGNPLPAITWYKDNHPLSASSSVTFLNRGQIIDIES AQISDAGIYKCVAINSAGATELFYSLQVHVPPSISGSNNMVAVVVNNLVRLECEARGTPA PSLTWLKDGSPVSSFANGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRV YVPPNIMGEEQNISVLISQAVELLCQSDAIPPPTLTWLKDGRPLLKKPGLSISENGSVLK IEEAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIYGSDEHAQLTVIEGNLISLLCES SGIPPPNLVWKKKGLPVLTDSAGRVRTLSGGRQLQISVVEKSDAGLYTCVASNVAGTAKK DYDLQVYIRPTISNSGSHPTEIIVTRGKSISLECEVQGIPQPKVTWMKDGRPLTKGRGME ILDEGRILQLKNIHVSDTGRYVCVAVNVAGMTDRKYDLSVHTPPSIIGNHGIPENTSVVE KNSVSLTCEASGIPLPSITWLKDGWPVSLSSSVRILSGGRTLRLMQTRVEDAGQYTCVVR NAAGEERKIFGLSVLVPPRIVSENTLEHVKVKEKQSVTLTCEVTGNPMPEITWHKDGQLL LEDDTHHIMSGGRFLKITNAQVSHTGRYACLASNTAGDKSKSFSLNVLVSPTIAGVDSDG GPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDN AGRYSCIATNEAGEMIKHYEVKVYIPPIINKGDLLGPGLSPKEVKIKVNNTLTLECEAYA IPSASLSWYKDGQPLKSDDHVNIAASGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDV NIQVPPSFQKLWEIGNMLDTGRSGEAKDVIINNPISLYCETNAAPPPTLTWYKDGRPLTS NDRVLILPGGRVLQIPRAKVEDAGRYMCVAVNEAGEDSLQYDVRVLLPPVIKGANSDLPE EVTVLVNKSTLMECLSSGNPVPRSSWQKDGQPLQEDGHHKFLSNGRILQILNTQITDIGR YVCVAENTAGSAKKYFNLNVHVPPSVIGPNPENLTVVVNNFISLTCEVSGFPPPDLSWLK NEQPIKVNTNALIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKVLLTVYVPPSIKD HGSESLSVVTVREGTSVSLECESNAVPPPVITWYKNGQMITESTHLEILADGQMLHIQKA EVSDTGQYVCRAINVAGRDDKNFHLNVYVSPSIEGPENERVVETVSNPVTLTCDATGIPP PTIAWLKNHKPIENSDSLEVHILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKNYILS IQVPPSIAGAEIPSEVSVLQGENVELACNANGIPTPLLQWLKDGKPLNRSETERIRVTVD GSTLNIYGALPSNVGKYTCVATNPAGEEDRIFNLNVYVPPAIRGNKEEAEKLMTLVDTSI NIECRASGTPPPQINWLKNGLPLPLSSHIRLLSGGQVIRIVRAQVSDVAMYTCVASNRAG VDNKHYSLRVLVPPNLDNAMGTEEITIVKGSSTSMTCFTDGTPTPRMSWLRDGQPLGPNT RLTITTQGMVLQLNKAETEDSGRYICIASNEAGEVNKHFILKVLEPPHINGSEEPVEISV IINNPLELTCFASGIPTPKITWMKDGRPLPQTDQVQTLGGGAVLRISSAQVEDTGRYTCL ASSTAGDDDKEYLVRVHVPPNIAGTDESQDFTVLRNRQVTLECKSDAVPPPVITWLKNGE RLQATPRVRILSGGRYLQINNADLSDTANYTCVASNIAGKTTREFILTVNVPPNIKRVPQ SLVIHLNTSTVLECLAEGVPAPRITWRKDGAVLSASHARYSILENGFLHIQSAHVADTGR YLCMATNAAGTDRRRIDLQVHVPPSIALGPTNITVTVNVQTTLACEAAGIPKPSIRWRKN GHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNDAGEDKRTVDLTVQVPPSIA DEPTDFVVTKHAPTVITCTASGVPVPSIHWTKNGLRLYPRGDGYRILSSGAIEIFATQLN HAGKYTCVARNAAGSAHRHVTLYVQEPPVIQPQPSELDVIVNNPILLPCEATGTPSPFIT WQKEGINVITAGKSHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPV ISPHPKEYITAVDKPISLPCEADGLPPPDITWHKDGRAVVESVRQRILSSGALQIAFAQP DDTGQYTCMAANAAGSSSTSAKLTVHVPPRIRSTEIQYTVNENSQAILPCMADGIPTPAI NWKKDNVLLANLLGKYTIEPYGELILENVVPEDSGAYTCVANNAAGEDTHMVSLTVHVLP TFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAYFDSVNGHSELVIERASK EDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPLGGNAVLNCEVKGDPAPT IQWSRKGVDIEINHRIRQLVNGSLAIYGTVNEDAGDYTCVATNDAGVVERSMSLTLQSPP IITLEPVETIINAGDKVLLNCQATGEPHPTITWSRQGQSIPWDDRVNVLSNNSLHIAAAR KEDTSEYECVARNLMGSVLVRVPVTVQVHGGYSQWSTWRACSVTCGKGIQKRSRLCNNPF PANGGKPCQGSDSEMRNCQRKLCPVDGSWSEWSPWEECTRSCGRGNRTRTRTCNNPSAQY GGRPCEGNAVEIIMCNIRPCPVHGAWSTWQPWSACSESCGKGTQIRTRLCNNPPPSFDGS YCDGAETQMQVCNERHCPVDGKWATWTSWSTCTVSCGGGARQRTRECSDPVPQYGGIRCE GSDVQSDFCNNDPCPTHGNWSPWSGWGMCSRTCNGGQMRRYRTCDNPHPSNGGRACGGPD SQIQRCNTDMCPVDGSWGNWHSWGQCSASCGGGEKTRKRLCNNPVPSKSGRPCPGDATQV SRCNTQACPGGPQRARGSVIGNINDVEFGIAFLNATVIDSPTSDTRIIQAKITNVPRSLG PAMRKIVSILNPIYWTTAKEIGEAVNGFTLTNAVFKRETQVEFATGEILRMTHVARGLDS DGALLLDIVVSGHVLQLQSPAEVTVKDYTEDYVQTGPGRLYAYSTRLFTIDGISVPYTWN HTVFYDEAQGRMPFLVETLHASSVESDYNQLEETLGFKIHASISKGDRSNQCPSGFALDS VGPFCADEDECAAGSPCSQICHNTVGTYYCSCSKGLTIAADGRTCQDVDECALGGHTCHA GQDCDNTIGSYRCVVRCGIGFRRTSDGLSCQDINECQESSPCHHRCFNAIGSFHCGCEPG YQLKGRKCIDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGT HQCRYNQICENTRGSYRCVCPRGFRSQGVGRPCMDINECEQVPKPCAYQCANTPGSFKCI CPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSSVRNNYQPQQHYRQYSHLYSSYSE YRNSRTSLSRTRRTIRKTCPEGSEASRDTCVDIDECENRDICQHECKNTFGSYQCICPPG YQLMLNGKTCQDVDECLEQSVRCGSNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCLKNC PPNDLECALSPYALEYKLVSLPFGIAANQDLIRLVAYTQDGVMHPRTTFLMVDEEQTVPF ALRDENLKGVVYTTRPLREPETYRMRVRASSYSANGTIEYQTTFIVYIAVSAYPY NT seq 16908 nt NT seq  +upstreamnt  +downstreamnt atgatttcctgggacattgtccacaccgtattcctgtttgctcttctttcttcttcccaa gctcaagatgcaagcccccagcccgaccccggggctgaggaaattcccgagggggcctcc accttggcttttgtgtttgatgtgacgggttccatgtacgatgacttagttcaggtgatc gaaggggcttccaaaattttggagacgtctttgaaaagacccaagagaccacttttcaac ttcgccttggtgccgttccatgatccagaaattggcccagtgacaattaccacagatccc aagaaatttcaatatgaactcagagaactgtatgttcagggtggtggcgattgtccagaa atgagtattggagctataaaaattgccttagaaatttctcttcctggctctttcatctat gttttcactgatgcacggtccaaggattatcggctcactcacgaggtgctccagcttatc caacagaaacagtcacaagtggtatttgtgctcactggagattgtgatgacaggggccat attggatataaagtctatgaagaaattgcctctacaagttctggtcaagtgttccatctg gacaaaaaacaagttaatgaggtgttaaaatgggtagaggaggcagtacagtcctctaaa gttcacctcttatcaacagatcatttggaacaagctgtaaacacttggaaaattcctttt gatcccagcctaaaagaggttactgtgtctctgagtggcccttctccagggattgaaatt cgcaatcccttagggaagctgataaaaaagggatttggcttgaacgagctattaaatatc cataactctgccaaggtggtgaatgttaaagagccagaggctggaatgtggacagtgaag acttcaagcagtggaaggcactctgttcgcatcactggccttagtactattgatttccga gctggtttttccagaaagcccaccctggacttcaaaaagacagtcagcagaccagtgcaa ggaatacctacctatgtgctgctgaatacttctggaatttccatcccagccagagtagat cgtcttgaacttctgagtacctcaggcagttctcttaagactattcctgttaaatactac ccagaccgaaaaccttatggcgtgtggaatatttctgactttataccaccgaatgaagct ttctttctcaaagtaacaggctatgataaggatgattatctattccagagggtatcaagt gtttccttttctagtatcatcccagatgctcccagagttacaatgcccaagaaaacccca ggatactacctgcagccaggccgaattccctgctctgttgagagtcttctaccgtttacc ctgagctttgtcagaaatggagttacacttggagtagaccagtatttaaaagaatcttcc agtgtgaactgggagattgaaaaggtcactttgtctgacgaaggcgcctatgagtgcatc gctgtgagcagcgtggggactggacgggcacagacattttttgatgtgtcagagccccct ccagtcatccaagtgcctgataatgttacagtccctcctggagaaagagcagttctgacc tgtctcgtcctcagtgcagtggattacaatctaacctggcagaggaatgacagagatgcc cgacaggcagacccagcgagaatgaggatcttggctaacctctccttggagctacggagt gtgaagttcagcgacgctggggagtatctctgtgtggtttccaatgaaggaggatcgtca gccgcttccgttttcctcacagtgcaagaaccacccaaagtcactgtgatgcccaagaat cagtcattcacaggaggatctgaggtctccatcaggtgttctgcaacaggttatcccaaa ccaaagatcacctggaccatcaatgatatgtttatcatgggttcacacaggtataggatg acctcagaaggtaacttattcatcaaaaatgcagttcccagagacgcagggatctacggt tgcctagcaagtaatgcagctggaacagacaaacagacttctaccctcagatacattgaa gccccaaagctgaatgtagttcagagtgagctcttggttgctcttggggatacaacagtt atggaatgtaaaacctctggtattcctccacctcaagttaaatggttcaaaggggatctt gagctgaggccatcaacattcctcattattgaccctctcttggggcttttgaagattcaa gaaactcaagacctggatgctggtgattatacgtgtgtagctgtcaatgatgctggaaga gtggctgggaagataactctggatgttggctcatctccagttttcatacaagaacctgct gatgtttctgtggaaattggctcaaatgtgacattaccttgctatgtccagggttatcca gaaccaaagattaaatggcagagatcagacaacatgcccatcttctcaagacccttttca gtgagttccatcagccaactaagaacaggagctctctttatttcaaatatatgggccaat gataaaggaacctatatttgtgaagctgaaaaccagtttggaaagatccagtcccagaca acaataacagtgacaggactagttgctccacttattggaatcagcccttcagtgaccagt gtcattgaaggacagcagcttactttgccttgtgctctgttggctggaaatcccattcca gaacgtcggtggattaagaattcagccatgttggtccaaaatccttacatcactgtacgc agtgacgggagtctccatattgaaagagttcgccttcaggatggaggcaaatatacttgt gtggccagtaatgttgctggaacttttaacaaaactaccactgtggatgtacatgtcctg ccaaccattcagcacgggcagcaggtactcagcacaattgaaggcattccagtaactcta ccatgcaaagcaagtggaattcccaagccatccatcatctggtccaagaaaggcgagctg atctccaccagcagtgctaagttttccacaggggctgacggaagtttgtatgtggtgtca cctgggggtgaagagagtggggagtacgtctgcaccgccaccaatgcggctggctacgcc aaaaggaaagtgcagctgactgtctatgtaaggcccagagtgtttggagatcaacgagga ctgtctcaagataagcctgttgagatctccgtccttgcaggggaagaggtgacgcttcca tgtgaagtgaagagcttacccccacccatcattacgtgggccaaagagacccagctcatc tctccattttctccaagacacacattcctcccttctggttcaatgaagatcattgagacc cgtgtttcagatagtgggatgtatctttgcgttgccacaaatatagctgggaacgtgact cagtctgttaaattaaatgtccatgttcctccaaagatacagcgtggccctaaacttatg aaagtccaagctggtcaaagagtggacatcctgtgcaacgctcaagggacgcctcttcct gtaatcacgtggttgaagggtggaagtgccgcgctggtggacggagcgcggcttgtgagc aattcagatggaacgttaagcattgacccagccctgctctcggatgccggcgtctataca tgtgtcgctactaacatggcaggcagtgatgaaacagaaataacgctacatgtccaagaa ccgcctacactggaagacctagaacctccatataacaccccattccaagaaagagtggcc agtgaacgcattgcatttccatgtcctgcaaaaggtacccccaaaccaactatcaaatgg atatggaatgggagagagctaacaggcagagagcctggtatttctatcttggaagatggc acattgttggtcattgcttctgttacaccctctgacaatggggagtatatctgtgtggcc gtcaatgaagctggaaccacagaaaaaaaatataacctcaaagtccacgttcctccagta attaaagataaagaacagataacaaatgtatctgtgctggtcaatcagctgaccaatctc ttttgcgaagttgaaggtactccttctcccatcgttatgtggtataaagatgaagttcag gtgactgaaagcagtaccattcagatcgtgaacaatgggaagatattaaagctcttcaga gtcgctccggaggacgcaggaagctattcctgtaaagcagttaatgttgcaggcacttct cagaagtattttaacgtcgaggtgttagtcccacccaccataataggtgctggctctcca aatgaagtctctgttgtcctcaaccgtgatatcacccttgaatgccaagtcaaaggcaca cccttccccgttattcactggttcaaggatggcaagcctttatttttagaagatcctaac actgaacttctagacagaggacaagttctgcatttaaagaatgcacgaagaagtgacaaa gggcgctaccagtgtgctgcatccagtggggctggcaaacaagtgaaggatataaaactg actgtctatattccacctagtattaaaggagggaatgttaccacagaaatttcagcattg atcaacagcatgattaaactggaatgtgaaacgcggggactgccgatgcctgctatttct tggtataaggatggccaaccagtcatttccagctcccaagcactttatattgataaagga caatttcttcatatccctcgagcacaggtctctgattcagcaacatatacgtgtcatgcc accaatgttgctggaactgctgaaaaatcattccatgtggatgtctacgttcctccagtg attgaaggtgacttggctgtgcctctgaataagcaagtggttattgctcattcgctgacc ctagagtgtaaagccacggggaaccctcctccagtcctcacctggttaaaagatggtgta cctgtgaaacccagtgacaacatccatacagaagctggtgggaagaaactagaaatcagg agagtcttagaagctgatcggggacagtatgtatgtgtggctaccagtgtggcaggagaa aaggaaatcaaatacgaagttgatgtcttagtgccaccagctatagaaggaggagacgaa acatcttacttcattgtgatgattaataacttattggagctagattgtcaagtgacaggc tctcccacgccaactatcatgtggctaaaggatggacagataattgatgaaagggatgga ttcaagattctactaaatggacgcaaattggttattacccaggctcaagtatcagatacg ggcctttatcgctgtgtggcaacaaacattgctggtgaccacaagaaggaatttgaagtt actattcatgttcctccaacaatcaaatcctcaggcctttctgagagagccatagtgaaa tacaagcctatcaccttgcagtgcatcgccaatggcattccaaatccatctatcacatgg ttaaaagatggccaacctattaacactgcccaaggaaaccttaagatccagtcttccggt cgagttttacaaattgccaaagccctgatggaagatgctggcagatacacttgtgtggcg accaacgcagctggggaaacacagcaccaccttcagctacatgtgcatgaaccgcctagt ctggaggatgcagggaagatgttgaatgagaccgtggtgctcaacaaccccattcagctg gagtgtaaggcagctggaaatccattacccgctattacatggtacaaagataatcatcca ctctcagcctccagcagtgtgactttcttgaacagaggacagatcattgatatcgaaagt gcccagatctctgacgctggcatatataaatgtgtggccatcaactcagccggagcgaca gagttattttatagtctgcaggttcatgtgcccccatcaatttctggcagcaataacatg gtggcagtggtggttaataacctggtgaggttagaatgtgaagccagaggaacacctgcc ccaagtctgacctggctgaaagatgggagccctgtctctagttttgctaacgggttacag gttctgtctggaggccgcatcctagcactgaccagcgctcaaatcagtgatactgggaga tacacctgcgttgctgtgaatgctgctggggagaaacaaagggacattgacctcagagta tatgttcctccgaatattatgggagaagaacagaacatctctgtcctcattagccaagct gtggagctactgtgtcagagtgatgctatccccccacctactttgacttggttgaaggat ggccgccccttgctgaagaaaccaggcctcagtatctctgaaaatggaagtgtgttaaag attgaagaggctcaagttcaagacactggtcgttacacttgtgaggcaacaaatgttgct ggaaaaactgagaaaaactataatgtcaacatttgggtaccaccaaatatttatggttct gatgaacatgctcaacttacagtcattgaagggaatctcattagtttattgtgtgaatca agtggtattccacccccaaatcttgtttggaagaagaaaggcttgccagtgctgactgat tctgcagggcgagtcagaactttatctggaggcagacagttacagatctcagttgtggaa aaatctgatgcagggctatacacatgtgtggcatcgaatgttgctggaactgcaaagaaa gactacgatctgcaagtctacattcgaccaactatatccaatagtggcagccatcctact gaaatcattgttactcgagggaagagtatttctttggagtgcgaggtgcagggtattcct cagccaaaagtgacctggatgaaagacggtcgccctttgacaaagggaaggggaatggaa atattggatgaaggtcgcatccttcagctgaagaacattcatgtatctgacacaggccgt tatgtgtgtgttgctgtgaatgtagcaggaatgactgacagaaaatatgacttaagtgta catacccctccaagcatcataggaaaccatgggatacctgaaaataccagtgtcgtggaa aagaactcagtgtctctgacttgtgaagcttcaggaattcccctgccttccattacctgg cttaaagatggatggcctgtcagccttagcagttctgtgagaattctctcaggaggcagg actctgcggttgatgcagaccagagtagaagatgctggccagtatacttgtgttgtaagg aatgcagctggtgaagaaaggaaaatctttgggctttcagtattagtgccacctcgcatt gtgagtgaaaatacattggaacatgtgaaggtaaaagagaagcagagtgttacactgacc tgtgaagtgacagggaatccaatgccagaaattacatggcacaaagatggacaactcctc ctagaagatgacacccatcacattatgtctggtggccgttttcttaaaattaccaatgcc caagtgtcacatactggaagatatgcatgtttggcttctaatacagctggcgacaagagc aaaagtttcagccttaatgtgttggtatctcctacaattgctggcgttgatagtgacggt ggccctgaagatgtcaccgttatccttaacagccccacatctttggtctgcgaagcttat tcatatcctccagccaccatcacctggtttaaggatggaacacctttagaatccaaccga aatattcgtattcttccaggaggtaggaccctgcagatcctaaatgcacaggaggataat gctggaagatactcttgtatagccactaatgaggcgggggaaatgataaagcactatgaa gtaaaggtctacattccacccatcatcaataaaggggacttactggggccaggtctttcc cctaaagaagtgaagatcaaagtcaacaataccctgactttggaatgtgaagcttatgca attccttctgcctctctcagctggtacaaggatggacagccccttaaatcagacgatcat gtcaatattgctgcaagtggccacacacttcaaataaaggaggctcagatatcagatact ggacggtatacttgtgtagcatctaatattgcaggtgaagatgagttggattttgatgtg aatatacaagttcctccaagttttcagaaactctgggaaataggaaacatgctggatacc ggcagaagtggtgaagccaaggatgtaatcatcaacaatccaatttctctttactgtgaa acaaatgctgctcctcctcctacactgacatggtacaaagatggccgtcctctgacctcg aatgatagagtgttgattctaccaggagggcgagtgttgcagattccccgtgccaaagta gaagatgcgggtcgatatatgtgtgtggctgtgaacgaagctggagaagattcccttcag tacgacgttcgtgtactcttgcctccagttattaagggagcaaatagtgatctccccgaa gaagtcaccgtgctggtgaataagagcacactgatggagtgtttatccagtggcaacccg gtgccaaggagttcctggcaaaaggatgggcaacctttgcaagaagatgggcatcataag tttctatctaatggaagaattctgcagattctaaacactcaaataacagatatcggcagg tatgtgtgtgttgctgagaacacagctggaagtgccaaaaaatattttaacctcaatgtt catgttcctccaagtgtcattggtcctaaccctgaaaatctcactgttgtggtgaacaat ttcatctctttgacctgtgaggtctctggttttccaccaccggatctcagctggctgaag aatgaacagcctatcaaagtaaatacaaatgctcttattgtacccggtggtcgaactcta cagattattcgggcaaaggtatctgatggtggcgaatacacttgtatagcgatcaaccaa gctggtgaaagcaagaaaaaagttctcctgactgtttatgtgcccccaagcattaaagat catggcagtgaatctctttcggtagttactgtaagagaggggacctcggtgtccctggag tgtgagtcaaatgctgtcccccctccagtcatcacctggtataagaatgggcagatgata acagagtctactcacttggagattttagcagatggacagatgctgcacatccagaaagcc gaggtgtctgacacaggacagtatgtatgtagagctataaatgtagcaggacgggatgat aaaaatttccacctcaatgtatatgtgtcccccagtatcgaagggcctgaaaatgaaagg gttgtcgagacagtcagcaatcctgtgaccttgacgtgtgacgccacgggaatcccgcct cccacaatagcatggttaaagaaccacaagcccatagaaaattctgactcactcgaagta catattttgtctggaggtagcaaactccagattgctcggtctcagcattcagatagtgga aactatacatgcattgcatcaaatatggagggaaaagcacagaaaaattacattctttca attcaagttcctccaagtattgctggtgctgaaattccaagtgaagtcagcgttcttcag ggagaaaacgttgagctggcctgcaatgcaaatggcattcccaccccacttcttcagtgg cttaaagatggaaagcccttaaacaggagtgaaacagaaagaatcagggtgactgtggat ggtagtacattaaatatttatggagctctcccatcaaacgtggggaaatacacatgcgtc gctactaaccctgctggagaagaagaccgaatttttaacttgaatgtctatgttccacct gcaattaggggtaataaagaagaagcagagaagctaatgactttggtggatacttcaata aatattgaatgcagagccagcgggacacctccaccacagataaactggctgaagaatgga cttcctctgcctctctcctcccacatccggttgttatcaggagggcaggttatcaggatt gtgagagctcaggtgtctgatgttgccatgtacacctgtgtagcctccaacagagctggg gtggataataagcattacagccttcgagttcttgtgccaccaaatctggacaatgcaatg ggaacagaggagatcacaatagtcaagggtagttctacctccatgacatgctttacagat ggaaccccaactcccaggatgtcctggcttagagatggccagcctctgggtcctaatacc cgtctgacaataaccactcaaggaatggttcttcagctcaacaaagcagagactgaagat tcaggaaggtacatctgcattgcctcaaatgaagctggagaagtcaacaaacactttatc ctgaaggtcctggaaccacctcatatcaatggatcagaagaacctgtagagatatcagtg attattaataatccacttgaacttacctgctttgcttctggaatcccaactcctaaaatc acctggatgaaagatggacggcccctcccacagacagatcaggtacaaactcttggaggt ggagcagtgcttcgaatatctagtgctcaggtggaggatacaggaagatatacatgtctg gcatccagtactgcaggagatgatgataaagaatatttagtgagagtgcatgtaccccct aatattgctggaactgatgagtcccaggatttcactgtgttacggaacagacaagtgaca ttggaatgcaaatcagatgcagtgcccccacctgtaatcacctggcttaaaaatggagaa cggttacaggcaacacctcgagtacgaatcctatctggagggagatacttgcaaattaat aacgcagatctaagtgatacagccaattatacttgtgtggccagcaacattgcaggaaag actacaagagaatttattctcactgtaaatgttcctccaaacataaagcgtgtcccccag agtcttgtcatccacttaaatacgtcaactgtattggaatgccttgctgagggtgtgcca gccccaaggataacatggagaaaggatggagctgttctctccgcaagtcatgcaagatac tccatcttggaaaatggattccttcatatccagtcggcacatgtggcagatactgggcga tatttgtgtatggctaccaatgctgctggaacagaccgcaggcgaatagatttacaagtc catgttcctccatccattgctctgggtcctaccaacataactgtaacagtaaatgttcaa actactctggcttgtgaggctgctgggataccaaaaccatcaatcaggtggaggaaaaat gggcatcttcttaatgtggaccaaaatcagaattcatacaggctcctttcttctggttca ctggtcattatttccccttctgtggatgacactgcaacttacgagtgcaccgtgacaaat gatgctggggaggataagagaactgtggatctcactgtccaagttccaccctccatagcc gatgagcctacggacttcgtagtaaccaaacatgcccccaccgtaatcacctgcactgct tcaggagttccagttccctcaattcactggacaaaaaatggtttaaggctatatcccagg ggagacggttacagaattctgtcctcaggagcaattgaaatatttgccactcagttaaac cacgctggaaaatatacctgtgttgccaggaacgcagctggttctgcacatcgacatgtg accctttatgtgcaggagcctccagtcattcagcctcagccaagtgaactcgacgtcatt gtaaacaatcccattttattaccgtgtgaagcaacagggacccccagtcctttcattact tggcaaaaagaaggcatcaatgtcatcactgcaggcaaaagccatgcagttcttcccagt ggcggcttgcagatctccagagctgtcagagaagatgctggtacttacatgtgcgtggct cagaatccggctggtacagccttaggcaaaatcaaattaaatgttcaagttcctccagtc attagcccccatccaaaggaatatatcactgctgtggataagcccatctctctaccgtgt gaggcagacggcctcccaccccctgacattacctggcataaagatgggcgtgcagttgtg gaatcggtccgccagcgcatcctcagctctggggccctgcagatagcgtttgctcagcct gatgacaccggccagtacacgtgcatggcagcaaacgcagcaggatcgagcagcacaagt gccaagctcactgtccatgtacctcctagaatccgaagtacagaaatacagtacacggtc aatgagaattcacaagccattcttccatgcatggctgatggaatccccacacccgcaatt aactggaaaaaagacaatgttcttttagctaacttgttgggaaaatataccattgaaccc tatggagaacttattctggaaaatgttgtgccggaggattctggtgcctatacctgtgtt gctaacaatgctgcaggtgaagacacccacatggtcagcctgactgtacacgttctcccc acttttactgaacttcctggagatgtgtcattaaataaaggagaacagctacgattaagc tgtaaagccactgggattccattgcccaagttaacatggaccttcaataacaatattatc ccagcctactttgacagtgtgaatggacacagtgaactcgttattgaaagagcgtcaaag gaggattcaggtacttacgtgtgcaccgcagagaacagcgttggttttgtgaaggcgatt ggatttgtttatgtgaaagaacctccagtcttcaaaggtgattacccttctaactggatt gaaccacttggtggtaatgcagtcttgaattgtgaagtgaaaggagatcctgccccaacc atccaatggagcaggaagggggtggatattgaaataaaccacagaatccgtcaactggtc aatggctccctggccatttatggcactgtaaatgaagatgctggtgattatacgtgcgta gctaccaatgacgctggggtggtggagcgcagcatgagtctgactctgcagagtcctcct attatcactcttgagccagtagaaaccattattaatgctggtgacaaagtcctattgaat tgtcaggcaactggagagcctcatccaaccattacatggtcccgtcaagggcagtctatc ccctgggatgaccgagttaatgtgttgtccaacaactcattacatattgctgctgctcgg aaagaagatacctctgaatatgaatgtgttgctcgaaacttgatgggttctgtccttgtc agagtgccggtcactgtccaggttcatggcggatattcccagtggtctacatggagagcc tgcagtgtcacctgtggaaaaggcatccaaaagagaagtcgtctgtgcaacaaccccttt ccagccaatggagggaagccttgccaagggtcagattcagaaatgcggaactgtcagcgt aagctgtgtccagtggatggaagctggtcagaatggagcccttgggaagaatgtacaaga agttgtggacgcggcaaccgaaccaggaccagaacttgcaataatccatcagctcagtat ggtgggcggccgtgtgaaggaaatgcagtagaaataatcatgtgcaacattaggccctgc ccagttcatggagcatggagcacctggcagccttggagtgcatgcagtgaaagttgtggc aaaggtacccagataaggacaagactgtgcaataatccaccaccatcatttgatggatcc tattgtgatggggcagaaacacagatgcaagtttgtaatgaaagacactgtccagttgat ggcaagtgggcaacttggaccagttggagtacctgtaccgtgtcctgtggaggaggtgcc agacagagaacaagggagtgctctgatcctgtcccccagtatggaggcatcagatgtgaa gggagtgatgtccagagtgatttttgcaataatgacccttgcccaactcacggcaactgg agtccttggagtggctggggaatgtgcagccggacatgcaatggagggcagatgcggcga taccgcacatgcgataaccctcatccctccaatggtggaagagcttgtggggggccagac tcccagatccagaggtgcaacactgacatgtgtcctgtggatggaagttggggaaactgg catagttggggccagtgctctgcctcttgtggaggaggtgaaaagactagaaaacggctg tgcaacaatccagtgccatctaaaagtgggcgcccctgtccaggagatgctactcaggtg tccagatgcaacacgcaagcatgtccaggtgggccccagcgagccagaggaagtgttatt ggaaatattaatgatgttgaatttggaattgctttccttaatgccacagtaatagatagt cctacctctgatactagaataatacaagccaaaattaccaacgtacctcgcagtcttggc ccagcaatgagaaaaatagtttctattctaaatcccatttactggacaacagcaaaggag ataggagaagcagtcaatggctttaccctcaccaatgcagtcttcaaaagagaaacccag gtggaatttgcaactggagaaatcttgcggatgactcatgttgcccggggcttggattct gatggtgctttgctcctcgatatcgttgtgagtggccatgtcctgcagcttcagtcacct gctgaagtcactgtaaaggattacacagaggactacgttcagacaggtcctgggcggttg tatgcctactcaacccggctgttcaccattgatggcatcagtgtcccatacacatggaac cacaccgtgttctatgatgaggcacagggaagaatgcctttcttggtagaaacccttcac gcttcctctgtggaatctgactacaaccagctggaagagacactgggctttaaaatccac gcttcaatttccaaaggagatcgcagtaatcagtgcccctcgggatttgccttagactca gttggacccttttgtgctgatgaagatgaatgtgccgcggggagtccctgctcccagatc tgccacaatacggtgggaacttattactgctcctgctcgaaaggcctcaccatagccgcg gatggaaggacttgtcaagatgtcgacgagtgtgctttaggtggacacacctgccacgct ggtcaggactgtgacaataccatcggatcctatcgctgtgtggtccgttgtggaattggc tttcgaagaacctctgatgggctgagttgccaagatattaatgaatgtcaagaatccagc ccctgtcaccaccgctgtttcaatgccataggaagttttcattgtggatgtgaacctggg tatcagctcaaaggcagaaaatgcatagatgtgaatgaatgtaggcagaacgtgtgcaga ccagatcagcactgcaagaacacccgcggaggctataagtgcattgatctttgtcccaac ggaatgaccaaggctgaaaacggaacctgcattgatattgatgaatgtaaagatgggacc catcagtgcagatacaaccagatatgtgagaatacaagaggcagctatcgctgtgtatgt cccagaggtttccggtctcaaggagttggaagaccctgtatggacattaatgaatgtgaa caagtgcctaagccttgtgcgtatcagtgcgccaacacccccggcagcttcaagtgtatc tgtccaccaggacaacatttattaggggacgggaaatcttgcgctggattggagaggctg cctaattatggcactcagtacagtagctataaccttgcacggttctcctctgtgagaaac aactatcaacctcaacagcattacagacaatactcccatctctacagctcctactcagag tatagaaacagcagaacatctctctccaggactagaaggactattaggaaaacttgccct gaaggctctgaggcgagccgtgacacatgtgtagatattgatgaatgtgaaaatagagac atttgccagcatgagtgtaaaaatacctttgggagctatcagtgtatctgtccacctggc tatcaactcatgctcaatggaaagacttgtcaagatgttgatgagtgtctggagcagagt gtgcgctgtgggtcaaatcgcatgtgcttcaacatgagaggaagctaccagtgcatcgat accccctgtccgcccaactaccaacgggatcctgtttcagggttctgcctcaagaattgt ccacccaatgatttggaatgtgccttgagcccatatgccttggaatacaaacttgtctct ctcccatttggaatagctgccaatcaagatttaatccggctggtagcatacacgcaggac ggagtgatgcatcccaggacaactttcctcatggtagatgaggaacagactgttcctttt gccttaagggatgaaaacctgaaaggagtggtgtatacaacacgaccattgcgagaacca gagacctaccgcatgagggttcgagcctcatcctacagtgccaacgggactattgaatat cagaccacattcatagtttatatagctgtgtctgcctatccctactaa

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