KEGG   Lutra lutra (Eurasian river otter): 125086956
Entry
125086956         CDS       T08100                                 
Name
(RefSeq) signal transducer and activator of transcription 3 isoform X1
  KO
K04692  signal transducer and activator of transcription 3
Organism
llv  Lutra lutra (Eurasian river otter)
Pathway
llv01521  EGFR tyrosine kinase inhibitor resistance
llv04062  Chemokine signaling pathway
llv04066  HIF-1 signaling pathway
llv04068  FoxO signaling pathway
llv04081  Hormone signaling
llv04217  Necroptosis
llv04550  Signaling pathways regulating pluripotency of stem cells
llv04630  JAK-STAT signaling pathway
llv04659  Th17 cell differentiation
llv04917  Prolactin signaling pathway
llv04920  Adipocytokine signaling pathway
llv04931  Insulin resistance
llv04933  AGE-RAGE signaling pathway in diabetic complications
llv04935  Growth hormone synthesis, secretion and action
llv05145  Toxoplasmosis
llv05160  Hepatitis C
llv05161  Hepatitis B
llv05162  Measles
llv05163  Human cytomegalovirus infection
llv05167  Kaposi sarcoma-associated herpesvirus infection
llv05169  Epstein-Barr virus infection
llv05171  Coronavirus disease - COVID-19
llv05200  Pathways in cancer
llv05203  Viral carcinogenesis
llv05205  Proteoglycans in cancer
llv05206  MicroRNAs in cancer
llv05207  Chemical carcinogenesis - receptor activation
llv05212  Pancreatic cancer
llv05221  Acute myeloid leukemia
llv05223  Non-small cell lung cancer
llv05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
llv05321  Inflammatory bowel disease
llv05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:llv00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    125086956
   04066 HIF-1 signaling pathway
    125086956
   04068 FoxO signaling pathway
    125086956
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    125086956
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    125086956
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    125086956
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    125086956
   04062 Chemokine signaling pathway
    125086956
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    125086956
   04917 Prolactin signaling pathway
    125086956
   04935 Growth hormone synthesis, secretion and action
    125086956
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    125086956
   05206 MicroRNAs in cancer
    125086956
   05205 Proteoglycans in cancer
    125086956
   05207 Chemical carcinogenesis - receptor activation
    125086956
   05203 Viral carcinogenesis
    125086956
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    125086956
  09162 Cancer: specific types
   05212 Pancreatic cancer
    125086956
   05221 Acute myeloid leukemia
    125086956
   05223 Non-small cell lung cancer
    125086956
  09172 Infectious disease: viral
   05161 Hepatitis B
    125086956
   05160 Hepatitis C
    125086956
   05171 Coronavirus disease - COVID-19
    125086956
   05162 Measles
    125086956
   05163 Human cytomegalovirus infection
    125086956
   05167 Kaposi sarcoma-associated herpesvirus infection
    125086956
   05169 Epstein-Barr virus infection
    125086956
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    125086956
  09163 Immune disease
   05321 Inflammatory bowel disease
    125086956
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    125086956
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    125086956
   04933 AGE-RAGE signaling pathway in diabetic complications
    125086956
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    125086956
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:llv03000]
    125086956
Transcription factors [BR:llv03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    125086956
SSDB
Motif
Pfam: STAT_alpha STAT_bind STAT_int STAT_linker SH2 Baculo_PEP_C
Other DBs
NCBI-GeneID: 125086956
NCBI-ProteinID: XP_047562626
LinkDB
Position
16:20057714..20131845
AA seq 770 aa
MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAAWIESQDWAYAASKESHATLVFHNL
LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA
TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK
SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRNIVSELAGLLSAMEYVQKTLTDEEL
ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ
HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY
QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN
GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY
NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS
GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST
KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM
DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGSAAPYLKTKFICVTPTTCSN
TIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMELTSECATSPM
NT seq 2313 nt   +upstreamnt  +downstreamnt
atggcccaatggaatcagctacagcagctcgacacgcggtacctggagcagcttcatcag
ctgtacagcgacagcttcccgatggagctgcggcagtttctagctgcttggatcgagagt
caggattgggcatatgcggccagcaaggaatcacatgcgactttggtgtttcataatctc
ctgggtgagattgaccagcaatacagccgtttcctgcaggagtcaaatgttctctatcag
cacaatctgcggagaattaagcagttcctccagagcagatatctggagaagccaatggag
attgcccgaatcgtggcccggtgcctgtgggaagagtcccgcctgctccagactgcagcc
actgcagcccagcaagggggccaggccaaccaccccacagccgccgtggtgacagagaag
cagcagatgctagagcagcacctacaagatgttcggaagcgagtacaggatctagaacag
aaaatgaaagtggtcgagaatctccaggatgactttgatttcaactacaaaaccctcaag
agtcaaggagacatgcaggatctgaatggaaacaaccagtcagtgaccaggcagaagatg
cagcaactggagcagatgctcacggcgctggaccagatgcgacggaacatcgtgagtgag
ttggcggggctgttgtccgcgatggagtatgtgcagaaaactctcacggacgaagagctg
gctgactggaagaggcggcaacagattgcgtgcattggaggccctcccaacatctgctta
gatcgcctcgaaaactggataacctcattagcggaatctcaacttcagacccgccaacaa
attaagaaactagaggagttgcagcagaaagtgtcctacaagggggatcccatcgtacag
caccggccaatgctggaggagaggattgtagagctgtttagaaacttaatgaaaagtgcc
ttcgtggtcgagcggcagccctgtatgcccatgcaccctgaccggccattggtcatcaag
actggagtccagttcactaccaaagtcagattgctggtcaagttccctgagttaaattat
cagcttaaaattaaagtgtgcattgacaaagactccggggatgttgcagctctcagaggg
tcccggaagtttaacattctgggcacaaacacaaaagtgatgaacatggaagagtccaac
aatggcagcctgtctgcagaattcaaacacctgaccctgagagagcaaagatgtggtaac
gggggccgagccaattgtgacgcctccctgattgttaccgaggagctgcacctgatcaca
tttgagactgaggtctatcaccaaggcctcaagattgaccttgagacccattccttgcca
gttgtggtgatctccaacatctgtcagatgccaaacgcctgggcatcaatcctgtggtat
aacatgctgaccaacaaccccaagaacgtgaacttcttcaccaagcccccgattggcacc
tgggatcaagtggccgaggtgctgagctggcagttctcctccaccacaaagcgagggctg
agcattgagcagttgacgacattggctgagaaactcttaggacccggtgtgaactattca
gggtgtcagattacgtgggctaaattttgcaaagaaaacatggctggcaaaggcttctcc
ttctgggtttggctagacaatatcattgaccttgtgaaaaagtacatcctcgctctttgg
aatgaagggtacataatgggttttatcagtaaggagcgggagcgggccatcttgagcacc
aagcccccaggcaccttcctgctacggttcagtgaaagcagcaaagaaggaggtgtcacc
ttcacttgggtagagaaggacatcagcggtaagacccagatccagtcagtggaaccatat
actaagcagcagctgaacaacatgtcatttgctgaaatcatcatgggctataagatcatg
gacgctaccaatatcctggtgtctccgctggtctatctctaccccgacattccgaaggag
gaggcgtttggaaagtactgtcgaccagagagccaggagcatcccgaagctgacccaggt
agtgctgctccatacctgaagaccaagtttatctgtgtgacaccaacgacgtgcagcaat
accattgacctgccgatgtccccccgcactttagattcattgatgcagtttggaaataat
ggtgaaggtgctgagccctcagcaggagggcagttcgagtccctcacgttcgacatggag
ttgacctcggagtgcgctacctccccgatgtga

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