Lutra lutra (Eurasian river otter): 125087205
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Entry
125087205 CDS
T08100
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
llv
Lutra lutra (Eurasian river otter)
Pathway
llv01521
EGFR tyrosine kinase inhibitor resistance
llv01522
Endocrine resistance
llv01524
Platinum drug resistance
llv04010
MAPK signaling pathway
llv04012
ErbB signaling pathway
llv04020
Calcium signaling pathway
llv04066
HIF-1 signaling pathway
llv04151
PI3K-Akt signaling pathway
llv04510
Focal adhesion
llv04520
Adherens junction
llv04530
Tight junction
llv05200
Pathways in cancer
llv05205
Proteoglycans in cancer
llv05206
MicroRNAs in cancer
llv05212
Pancreatic cancer
llv05213
Endometrial cancer
llv05215
Prostate cancer
llv05219
Bladder cancer
llv05223
Non-small cell lung cancer
llv05224
Breast cancer
llv05226
Gastric cancer
llv05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
llv00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
125087205
04012 ErbB signaling pathway
125087205
04066 HIF-1 signaling pathway
125087205
04020 Calcium signaling pathway
125087205
04151 PI3K-Akt signaling pathway
125087205
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
125087205
04520 Adherens junction
125087205
04530 Tight junction
125087205
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
125087205
05206 MicroRNAs in cancer
125087205
05205 Proteoglycans in cancer
125087205
05230 Central carbon metabolism in cancer
125087205
09162 Cancer: specific types
05212 Pancreatic cancer
125087205
05226 Gastric cancer
125087205
05219 Bladder cancer
125087205
05215 Prostate cancer
125087205
05213 Endometrial cancer
125087205
05224 Breast cancer
125087205
05223 Non-small cell lung cancer
125087205
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
125087205
01524 Platinum drug resistance
125087205
01522 Endocrine resistance
125087205
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
llv01001
]
125087205
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
llv04147
]
125087205
04090 CD molecules [BR:
llv04090
]
125087205
Enzymes [BR:
llv01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
125087205
Protein kinases [BR:
llv01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
125087205
Exosome [BR:
llv04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
125087205
CD molecules [BR:
llv04090
]
Proteins
125087205
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
Haspin_kinase
Kinase-like
APH
Motif
Other DBs
NCBI-GeneID:
125087205
NCBI-ProteinID:
XP_047563236
LinkDB
All DBs
Position
16:complement(22324033..22348948)
Genome browser
AA seq
1260 aa
AA seq
DB search
MELAAWCRWGLLLALLPSGVVGTQVCTGTDMKLRLPASPETHLDMLRHLYQACQVVQGNL
ELTYLPANASLSFLQDIQEVQGYVLIAHSQVRQVPLQRLRIVRGTQLFEDHYALAVLDNG
DPPEGGPSVAGAAPEGLRELQLRSLTEILKGGVLIQRNPQLCHQDTILWKDIFHKNNQLA
LTLIDTNRSRACQPCSPACKDPHCWGASSGDCQSLTRTVCAGGCARCKGPKPTDCCHEQC
AAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACP
YNYLSTDVGSCTLVCPLNNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLREVRAVTSAN
IQEFAGCKKIFGSLAFLPESFEGDPASNTAPLQPDQLRVFEALEEITGYLYISAWPDSLP
DLSFFQNLRVIRGRVLHDGAYSLTLRGLGISSLGLRSLRELGSGLALIHRNAHLCFIHTV
PWDQLFRNPHQALLHSANRPEAECVGEGLACYPLCAHGHCWGPGPTQCVNCSQFLRGQEC
VEECRVLQGLPREYVKDRYCLPCHSECRPQNGSVTCFGSEADQCVACAHYKDNPFCVSRC
PSGVKPDLSFMPIWKFADEEGTCQPCPINCTHSCADLDERGCPAEQRASPVTSIIAAVVG
ILLAVLVGLVLGILIKRRRQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETEL
RKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSP
YVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVR
LVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFT
HQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWM
IDSECRPRFRELVAEFSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDDDMGDLVDA
EEYLVPRQGFFCPDPAPGAGGLAHRRHRSSSTRSGGGELTMGLEPSEEEPPKSPRAPSEG
AGSDVFDGDLGMGAAKGLQSLPPQDPSPLQRYSEDPTAPLAPETDGYVVPLTCSPQPEYV
NQPEVWPQPPSPLEGPLPPSRPAGATLERPKTLSPKTLSPGKNGVVKDIFAFGSAVENPE
YLVPQGRAAPQPHPPPAFSPAFDNLYYWDQDPSERGSPPSTFEGTPTAENPEYLGLDVPV
NT seq
3783 nt
NT seq
+upstream
nt +downstream
nt
atggagctggcggcctggtgccgctgggggctcctgctcgccctcctgccctccggagtc
gtgggcacccaagtgtgcaccggcacagacatgaagctgcggctcccagccagtcccgag
acccacctggatatgctccgccacctctaccaggcctgtcaagtggtgcagggtaacctg
gagctcacctacctgcctgccaatgccagcctgtccttcctgcaggatatccaggaggtg
cagggctacgtgctcatcgctcacagccaagtgagacaggtcccgctgcagaggctccga
atcgtgcggggcacccagctctttgaggatcactatgccctggccgtgctggacaatgga
gatccgcccgaggggggcccctctgtggcaggggctgccccagaagggctgcgggagctg
cagcttcgaagcctcacagagatcctgaagggcggggtcttgattcagcggaacccacag
ctctgccaccaggacacgatcctgtggaaggacatcttccacaagaacaaccagctggcc
ctcacgctgatagacaccaaccgctctcgggcctgccagccctgttctccagcttgtaaa
gacccccactgctggggagcaagttccggggactgtcagagcttgacgcgaaccgtctgt
gctggcggctgtgcccgatgcaagggcccgaaacccacggactgctgccacgagcagtgt
gcagctggctgcacgggccccaagcactcggactgcctggcctgccttcacttcaaccac
agtggcatctgtgagctgcactgtccagccctggtcacctacaacacagacaccttcgaa
tccatgcccaaccctgagggccggtacaccttcggagccagctgtgtgaccgcctgtccc
tacaattacctgtcaacggatgtgggatcctgcaccttggtctgtcccctgaacaaccaa
gaggtgacggctgaggacggaacgcagcggtgtgagaaatgcagcaagccctgtgcccga
gtgtgctatggcctgggcatggagcacttgcgggaggtgagggcggtcaccagcgccaac
atccaagagtttgccggctgcaagaagatctttgggagcctggcgtttctgccagaaagc
tttgagggagacccagcctccaacactgcccccctccagcctgaccagctcagagtgttt
gaggctctggaggagatcacaggttacctgtacatctcagcatggccagacagcctgcct
gacctcagtttcttccagaacctgcgagtcatccggggacgagttctgcatgacggcgcc
tactcactgaccctgcgagggctgggcatcagctcgctggggctgcgctcgctgcgggaa
ctgggcagcgggctggccctcatccaccgcaacgcccacctgtgcttcatacacacggtg
ccctgggaccagctcttccggaacccgcaccaggccctgctccacagcgccaatcggcca
gaggccgagtgtgtgggcgagggcctggcctgctacccgctgtgcgcccatgggcactgc
tggggtccggggcccacccagtgcgtcaactgcagccaattccttcggggccaggagtgc
gtggaggaatgccgagtactgcaggggctaccccgggagtatgtgaaggacaggtactgt
ctcccgtgccactccgagtgtcggccgcagaatggctcagtgacctgctttgggtcggaa
gctgaccagtgtgtggcctgcgcccactacaaggacaatcccttctgcgtgtctcgctgc
cccagtggcgtgaaacccgacctctccttcatgcccatttggaagttcgccgatgaggag
ggcacgtgccagccgtgccccatcaactgcacccactcctgtgcggatctggacgagagg
ggctgccccgccgagcagagagccagccctgtgacgtccattattgccgctgtggtgggc
attctgctggccgtgcttgtggggctggtcctcggcatcctaatcaagcgaaggcggcag
aagatccgcaagtacacgatgcgaaggctgctgcaggaaaccgagctggtggagccgctg
acgcctagcggagccatgcccaaccaggctcagatgcggatcctgaaagagacagaactg
aggaaggtgaaagtgcttggatccggagcctttggcaccgtttacaagggcatctggatc
cctgatggggaaaatgtgaagatcccagtggccattaaagtgttgagggaaaacacatct
cccaaagccaacaaagaaatcttggacgaagcatatgtgatggctggcgtgggctcccca
tatgtgtcccgccttctgggcatctgcctgacatccacagtgcagctggtgacacagctt
atgccctatggctgcctcttagaccacgtccgagagcaccgtgggcgcctgggctcccag
gacctgctgaactggtgtgtgcagatcgctaaggggatgagctacttggaggacgttcgg
ctggtgcacagggacctggctgcccggaacgtgctggtcaagagtcccaaccatgtcaag
ataacagactttgggctggctcggttgctggacattgacgagaccgagtaccacgcggat
gggggcaaggtgcccatcaagtggatggcgctggagtccattctccgccggcggttcacc
caccagagtgacgtgtggagctatggtgtgactgtgtgggaactgatgacttttggggcc
aaaccttacgatgggatcccagcccgggagatccctgacctgctggaaaagggggaacgg
ctgccccagccccccatctgcaccattgacgtctacatgatcatggtcaaatgttggatg
atagactctgaatgtcgaccacggttccgggagttggtggccgaattctcccgcatggcc
agggacccccagcgcttcgtggtcatccagaatgaagacttgggccccgccagcccactg
gacagcaccttctaccgctcgctgctggaagatgatgacatgggggacctggtggatgct
gaggagtacctggtgccccggcaggggttcttctgccccgaccctgccccaggtgctggg
ggcctggcccaccgcaggcaccgcagctcgtccacgaggagtggcggtggtgagctgaca
atgggactggagccctccgaggaggagcccccaaagtctccacgggcaccctcagagggg
gctggctctgacgtgtttgatggcgacttgggaatgggggcagccaaggggctgcagagc
cttcccccacaggaccccagccctctacagcggtacagtgaggaccctactgcacccctg
gccccagagactgatggctatgttgtccccctgacctgcagcccccagcctgaatacgtg
aaccagccggaggtttggccgcagcccccctcgcccctagaaggccctctgcctccttct
cgacctgccggtgccactctggaaaggcccaagactctgtcccccaagactctctcccct
ggcaagaatggggttgtcaaagacatttttgcctttgggagtgctgtggagaaccctgag
tacttggtaccccagggcagggctgcccctcagccccaccctcctccagccttcagtcca
gcctttgacaacctctattactgggaccaggacccatcagagcggggctctccacccagc
acctttgaagggacccctacagcagagaaccctgagtacctgggcctggatgtgccagtg
tga
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