Lutra lutra (Eurasian river otter): 125089071
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Entry
125089071 CDS
T08100
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 10
KO
K04418
mitogen-activated protein kinase kinase kinase 10 [EC:
2.7.11.25
]
Organism
llv
Lutra lutra (Eurasian river otter)
Pathway
llv04010
MAPK signaling pathway
llv05016
Huntington disease
llv05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
llv00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
125089071
09160 Human Diseases
09164 Neurodegenerative disease
05016 Huntington disease
125089071
05022 Pathways of neurodegeneration - multiple diseases
125089071
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
llv01001
]
125089071
Enzymes [BR:
llv01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.25 mitogen-activated protein kinase kinase kinase
125089071
Protein kinases [BR:
llv01001
]
Serine/threonine kinases: TKL group
MLK family
125089071
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH3_9
SH3_1
SH3_2
Pkinase_fungal
RNase_Y_N
Motif
Other DBs
NCBI-GeneID:
125089071
NCBI-ProteinID:
XP_047566843
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All DBs
Position
17:46770104..46785069
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AA seq
936 aa
AA seq
DB search
MEEEEGGTAKEWGTTPTGPVWTAVFDYEAAGDEELTLRRGDRVQVLSQDCAVSGDEGWWT
GQLPSGRVGVFPSNYVAPGAPAAPAGLQLPQEIPFHELQLEEIIGVGGFGKVYRALWRGE
EVAVKAARLDPERDPAVTAEQVRQEARLFGALKHPNIIALRGACLSPPHLCLVMEYARGG
ALSRVLAGRRVPPHVLVNWAVQVARGMNYLHNDAPVPIIHRDLKSINILILEAIENHNLA
DTVLKITDFGLAREWHKTTKMSAAGTYAWMAPEVIRLSLFSKSSDVWSFGVLLWELLTGE
VPYREIDALAVAYGVAMNKLTLPIPSTCPEPFARLLEECWDPEPHGRPDFGSILKRLEVI
EQSALFQMPLESFHSLQEDWKLEIQHMFDDLRTKEKELRSREEELLRAAQEQRFQEEQLR
RREQELAEREMDIVERELHLLMCQLSQEKPRVRKRKGNFKRSRLLKLREGGSHISLPSGF
EHKITVQASPTLDKRKGSDGASPPASPSIIPRLRAIRLTPVDGGGSSSGSSGGGSGTWGR
SGPPKKEELVGGKKKGRTWGPSSTLQKERAGGEERLKALGEGSKQWSSSAPNLGKSPKHT
PIAPGFASLNEMEEFAEADGDNSVPPSPYTTPSYLTVPLPAEPSPGAPAPLSRPGHGGRR
RCELALLGCATLLGAVGLGADVAEARAADCEEQRRWLDGLFPRAGRFPRGLSPPGRSPGR
RDDAAPGPGLAPSATLVSLSSVSDCNSTRSLLRSDSDEAAPAAPSPPPSPPSTNPLVDLE
LESFKKDPRQSLTPTHVTAARAVSRGHRRTPSDGALGQRGAPEPAAPRPGPRDPLDFPRL
SDPQTLFPTHRRPPEFPGRPTTLTFAPRPRPAASRPRLDPWKLVSFGRTLGISPPSRPDT
PESPGLPGMQPTLLDMDMEGQSQDSTVPLCGAHGSR
NT seq
2811 nt
NT seq
+upstream
nt +downstream
nt
atggaggaggaggagggggggacggccaaggagtggggcacgacccccacggggcccgtc
tggaccgcggtgttcgactacgaggcggcgggcgatgaggagctgaccctgcggaggggc
gaccgcgtccaggtgctttcccaggactgtgcggtgtcgggcgacgagggctggtggacc
gggcagctacccagcggccgtgtgggcgttttccccagcaactacgtagcccccggcgcc
cccgccgcgcccgcgggcctccagctgccccaggagatccctttccacgagctgcagcta
gaggagatcatcggtgtagggggctttggcaaggtctaccgggccctgtggcgcggcgag
gaggtggctgtcaaggccgcccggctggaccctgagcgggacccggcagtgacagcagag
caggtgcgccaggaggcccggctcttcggagccctgaagcaccccaacatcattgccctc
cgaggtgcctgcctcagccccccacacctctgcctggtgatggagtatgccagggggggc
gcactgagcagggtgctggcaggccgccgggtgccccctcacgtgctggtcaactgggct
gtgcaggtggcccggggcatgaactacctacacaatgatgcccctgtgcccatcatccac
cgggacctcaagtccatcaacatccttatcctggaggccatcgagaaccacaacctcgca
gacacggtgctcaagatcacagacttcggcctcgcccgcgagtggcacaagaccaccaaa
atgagcgctgcggggacttacgcctggatggctccagaggtcatccgcctctccctcttc
tccaaaagcagtgacgtctggagcttcggggtgctgctctgggagctgctgacgggtgag
gtcccctaccgtgaaatcgacgccttggccgtggcgtatggcgtggctatgaacaagctg
acgctgcccatcccctccacgtgccccgagccctttgcccgcctcctggaggaatgctgg
gacccagaaccccacgggcggccagatttcgggagcatcttgaagcggcttgaagtcatc
gaacagtcagctctgttccagatgccactggagtccttccactcgctgcaggaagactgg
aagctggaaattcagcatatgttcgatgacctccggaccaaagagaaggagctccggagt
cgggaggaggagctgctgcgggccgctcaggagcagcgcttccaggaggagcagctgcgg
cggcgggagcaggagctggcggagcgcgagatggacatcgtggagcgggagctgcacctg
ctcatgtgccagctgagccaggagaagccgcgggtccgcaaacgcaagggcaacttcaag
cgcagccgcctcctcaagctgcgggaaggcggcagccacatcagcctgccctccggcttc
gagcataagatcacagtccaggcctctccaaccctggacaagcggaaaggatccgacggg
gccagccccccagcgagccccagcatcattccccggctgagggccattcgcttgactcct
gtggacggtggtggcagcagcagtggcagcagcggtggtggcagtgggacatggggccgc
agcgggcccccaaagaaggaagaactggttggaggcaagaagaagggccggacctgggga
cccagctccaccctgcagaaggagcgggctggaggggaggagaggctgaaggccctgggg
gaaggaagcaaacagtggtcatcaagcgcccccaacctgggcaaatcccccaaacataca
ccgatcgccccaggcttcgccagcctcaatgagatggaggagttcgcggaggcggacgga
gacaacagcgtgcccccctccccctacaccaccccgtcctacctcaccgtgcccctgccg
gccgagccctccccgggggcgcccgcgcccctctcccggccgggccacggcggccggcgg
cgctgcgagctggccctgctgggctgcgccacgctgctgggcgccgtgggtctgggcgca
gacgtggccgaggcgcgcgcggcggactgcgaggagcagcggcgctggctggacggcctc
ttcccccgcgccggccgcttcccgcggggcctcagcccgcccgggcgctcgcccggccgc
cgcgacgacgcggcccccggcccgggcctggcgccctcggccaccctggtgtcgctgtcg
tccgtgtctgactgcaactccacgcgttcgctgctgcgctccgacagcgacgaggccgcg
ccggccgcgccctccccgcccccctccccgcccagcaccaaccccctagtggacctggag
ctggagagcttcaagaaagacccccgccagtcgctcacgcccacccacgtcacggccgcg
cgcgcagtgagccgcgggcaccggcggacgccgtcggacggtgcgctggggcagcggggg
gcgcctgagcccgcggctccccgccctggccctcgagaccccctggacttcccccgtctg
tccgacccccagaccttgttcccgacccaccgccggccccctgagttccctggccgccct
accaccctgaccttcgccccaagaccccggccggctgccagccgcccccgcctggacccc
tggaaactggtctcctttggccggacactcggcatctcgcctcctagcaggccggacacc
ccagagagccccggactccctggcatgcagcccacgctgcttgacatggacatggagggg
cagagccaggacagcaccgtgcccctgtgtggggcccatggctcccgctga
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