KEGG   Lutra lutra (Eurasian river otter): 125093220
Entry
125093220         CDS       T08100                                 
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
llv  Lutra lutra (Eurasian river otter)
Pathway
llv04010  MAPK signaling pathway
llv04020  Calcium signaling pathway
llv04022  cGMP-PKG signaling pathway
llv04114  Oocyte meiosis
llv04218  Cellular senescence
llv04310  Wnt signaling pathway
llv04360  Axon guidance
llv04370  VEGF signaling pathway
llv04380  Osteoclast differentiation
llv04625  C-type lectin receptor signaling pathway
llv04650  Natural killer cell mediated cytotoxicity
llv04658  Th1 and Th2 cell differentiation
llv04659  Th17 cell differentiation
llv04660  T cell receptor signaling pathway
llv04662  B cell receptor signaling pathway
llv04720  Long-term potentiation
llv04724  Glutamatergic synapse
llv04728  Dopaminergic synapse
llv04921  Oxytocin signaling pathway
llv04922  Glucagon signaling pathway
llv04924  Renin secretion
llv05010  Alzheimer disease
llv05014  Amyotrophic lateral sclerosis
llv05020  Prion disease
llv05022  Pathways of neurodegeneration - multiple diseases
llv05031  Amphetamine addiction
llv05152  Tuberculosis
llv05163  Human cytomegalovirus infection
llv05166  Human T-cell leukemia virus 1 infection
llv05167  Kaposi sarcoma-associated herpesvirus infection
llv05170  Human immunodeficiency virus 1 infection
llv05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
llv05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:llv00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    125093220
   04310 Wnt signaling pathway
    125093220
   04370 VEGF signaling pathway
    125093220
   04020 Calcium signaling pathway
    125093220
   04022 cGMP-PKG signaling pathway
    125093220
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    125093220
   04218 Cellular senescence
    125093220
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    125093220
   04650 Natural killer cell mediated cytotoxicity
    125093220
   04660 T cell receptor signaling pathway
    125093220
   04658 Th1 and Th2 cell differentiation
    125093220
   04659 Th17 cell differentiation
    125093220
   04662 B cell receptor signaling pathway
    125093220
  09152 Endocrine system
   04922 Glucagon signaling pathway
    125093220
   04921 Oxytocin signaling pathway
    125093220
   04924 Renin secretion
    125093220
  09156 Nervous system
   04724 Glutamatergic synapse
    125093220
   04728 Dopaminergic synapse
    125093220
   04720 Long-term potentiation
    125093220
  09158 Development and regeneration
   04360 Axon guidance
    125093220
   04380 Osteoclast differentiation
    125093220
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    125093220
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    125093220
   05170 Human immunodeficiency virus 1 infection
    125093220
   05163 Human cytomegalovirus infection
    125093220
   05167 Kaposi sarcoma-associated herpesvirus infection
    125093220
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    125093220
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    125093220
   05014 Amyotrophic lateral sclerosis
    125093220
   05020 Prion disease
    125093220
   05022 Pathways of neurodegeneration - multiple diseases
    125093220
  09165 Substance dependence
   05031 Amphetamine addiction
    125093220
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    125093220
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:llv01009]
    125093220
Enzymes [BR:llv01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     125093220
Protein phosphatases and associated proteins [BR:llv01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     125093220
SSDB
Motif
Pfam: Metallophos
Other DBs
NCBI-GeneID: 125093220
NCBI-ProteinID: XP_047574039
LinkDB
Position
2:complement(102000435..102323531)
AA seq 521 aa
MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV
ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV
DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD
AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG
NEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP
SLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK
VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV
LTLKGLTPTGMLPSGVLSGGKQTLQSATVEAIEADEAIKGFSPQHKITSFEEAKGLDRIN
ERMPPRRDAMPSDANLNSINKALASETNGTDSNGSNSSNIQ
NT seq 1566 nt   +upstreamnt  +downstreamnt
atgtccgagcccaaggcaattgatcccaagttgtcgacgaccgacagggtggtgaaagct
gtcccatttcctccaagtcaccggcttacagcaaaagaagtgtttgataacgatgggaaa
ccccgtgtggatatcttaaaggcacatctcatgaaggagggcaggctggaagagagcgtt
gcattgagaataataacagagggggcttcaattctccgacaggaaaaaaatttgctggat
attgatgcaccagtcacagtttgtggggacatccatggacaattctttgacttgatgaag
ctttttgaagtggggggatctcctgccaacactcgctacctcttcttaggggactatgtt
gacagagggtacttcagtatcgaatgtgtgctgtatttgtgggccttgaaaattctttat
cctaaaacactgtttttacttcgtggaaatcatgaatgtagacatctaacagagtatttc
acatttaaacaagaatgtaaaataaagtattcagaacgcgtctatgacgcctgtatggat
gcctttgactgcctgcccctggctgccctgatgaaccagcagttcctgtgtgtccacggt
ggtttgtctcccgagattaacaccttagacgatatcagaaaattagaccgattcaaagaa
ccacctgcttatggacctatgtgtgatatcctgtggtcagaccccctggaggattttgga
aatgagaagactcaggaacatttcactcacaacacagtcagggggtgttcgtacttctac
agttacccggctgtatgtgaattcttacagcacaataatttgttatctatactccgagcc
catgaagcccaagatgcagggtatcgcatgtacaggaaaagccaaacgacaggcttccct
tctctaattacaattttctcagcaccaaattacttagatgtatacaataacaaagctgca
gtattgaagtatgagaacaacgtcatgaatatcaggcaattcaactgttctcctcaccca
tactggcttccaaatttcatggatgtcttcacttggtccctgccatttgttggggaaaaa
gtgactgagatgctggtaaatgtgctcaacatctgctcagatgatgaactggggtcagaa
gaagatggatttgatggtgcaacagccgcggcccggaaggaggtgataagaaacaagatc
cgagcaataggcaaaatggcccgagtgttctcggttctcagagaagagagcgagagcgtg
ctgacgctgaaaggcttgacccccacgggcatgctccccagcggagtgctttctggaggg
aagcagacactgcaaagcgctactgttgaggctattgaggctgatgaagctatcaaagga
ttttcaccacaacataagatcactagcttcgaggaggccaagggcttagaccgaattaat
gagaggatgccacctcgcagagatgccatgccctctgacgccaaccttaactccatcaac
aaggctctcgcctcagagactaacggcacggacagcaatggcagtaatagcagcaatatc
cagtga

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