Lutra lutra (Eurasian river otter): 125095291
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Entry
125095291 CDS
T08100
Name
(RefSeq) bifunctional purine biosynthesis protein ATIC
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
llv
Lutra lutra (Eurasian river otter)
Pathway
llv00230
Purine metabolism
llv00670
One carbon pool by folate
llv01100
Metabolic pathways
llv01523
Antifolate resistance
Module
llv_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
llv00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
125095291
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
125095291
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
125095291
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
llv04147
]
125095291
Enzymes [BR:
llv01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
125095291
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
125095291
Exosome [BR:
llv04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
125095291
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SSDB
Ortholog
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Gene cluster
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Ribosomal_L12_N
Motif
Other DBs
NCBI-GeneID:
125095291
NCBI-ProteinID:
XP_047577506
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All DBs
Position
3:26022926..26052044
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AA seq
592 aa
AA seq
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MAPSQLALFSVSDKTGLVEFARNLTSVGLNLIASGGTAKALRDAGLAVRDVSELTGFPEM
LGGRVKTLHPAVHAGILARNIPEDNADMARLDFSLIRVVVCNLYPFVKTVASPDVTVEQA
VEQIDIGGVTLLRAAAKNHARVTVICEPEDYAAVSTEMQSSNSKDTSLETRRQLALKAFT
HTAQYDEAISDYFRRQYSKGISQMPLRYGMNPHQTPAQLYTLKPKLPITVLNGAPGFINL
CDALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLGEDEAKVCMVYDLYKTLTPIS
TAYARARGADRMSSFGDFVALSDVCDVPTAKIISREVSDGIVAPGYEDEALKILSKKKNG
NYCVLQMDQSYNPDENEVRTLFGLRLSQKRNNGVIERSLFSNVVTKNKDLPESALRDLIV
ATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANYWWLRHHPQVLSMKFKT
GVKRAEISNAIDQYVTGTIGEDEDLIKWKALFEEVPELLTEAEKKEWVDKLSEVSLSSDA
FFPFRDNVDRAKRSGVAYIAAPSGSAADKVVIEACDELGIILAHTNLRLFHH
NT seq
1779 nt
NT seq
+upstream
nt +downstream
nt
atggcacccagccagctcgccttatttagtgtctctgacaaaacgggccttgtggaattt
gccagaaacctaacttcagttggtttgaatctgatcgcctctggagggactgcaaaagct
ctcagggatgcgggtctggcagtcagagatgtctctgagctgacgggatttcctgaaatg
ttaggggggcgtgtgaaaaccttgcatcctgcagtccatgctggaatcttggctcgtaat
atcccagaagataatgctgacatggccagacttgatttcagtcttataagagttgtcgtc
tgcaatctatatccctttgtgaagacagtggcttctccagatgtaactgttgaacaggct
gttgagcagattgatattggcggagtaaccctattgagagcagcagccaaaaaccatgct
cgggtgacagtaatatgtgaacccgaggactatgcagctgtgtccacagagatgcagagc
tccaacagcaaagacacctccttggagaccagacgtcagttagccttgaaggccttcact
catacggcacaatatgatgaagcaatttcagattacttcaggagacagtatagtaaagga
atatctcagatgcctttgaggtatggaatgaaccctcatcaaactcctgcccagttatac
acgctgaagcccaagcttcccatcacagttctaaatggagcccctggatttataaacttg
tgtgatgctttgaatgcctggcagctggtgaaggaactcaaagaagctttaggcattcca
gcagctgcctctttcaaacatgtcagcccagcaggtgctgctgttggaattccactcggt
gaagacgaggccaaagtctgcatggtctatgatctgtataaaacccttacacccatatca
actgcatatgcaagagcaagaggggctgataggatgtcttcatttggtgactttgttgca
ttatctgatgtttgtgatgttcctactgccaaaattatctccagagaggtatctgatggt
attgttgccccaggatatgaagatgaagctttgaaaatactttctaaaaaaaaaaatgga
aactactgtgttcttcagatggatcagtcctacaatccagatgaaaacgaagttcgaact
ctctttggtcttcgtttaagtcagaagagaaataatggtgtcatcgaaaggtcattattt
agcaacgtggtgaccaagaataaagatttgccagagtctgcgctcagagacctcattgta
gccaccattgctgtgaagtacacacagtctaactccgtgtgctatgccaagaatggtcag
gttatcggcattggagcaggacagcagtctcgaatacactgcacacgccttgcaggggat
aaagcaaattattggtggcttagacatcatccacaagtcctttcaatgaagtttaaaact
ggagtgaagagagcagaaatctccaatgccattgatcagtatgttactggaaccattggc
gaggatgaggatttgataaagtggaaggcattgtttgaagaagtgcctgaattattaact
gaagcagagaagaaggaatgggttgacaaacttagtgaagtttctctcagctctgatgcc
ttctttcctttcagggataatgtagacagagctaaaaggagcggtgtggcctacattgct
gctccttctggttctgctgctgacaaagttgtgattgaggcttgcgatgaattgggaata
atccttgctcatacgaatcttcggctctttcatcactga
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