Lutra lutra (Eurasian river otter): 125100123
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Entry
125100123 CDS
T08100
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X1
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
llv
Lutra lutra (Eurasian river otter)
Pathway
llv00230
Purine metabolism
llv01100
Metabolic pathways
llv04927
Cortisol synthesis and secretion
llv04934
Cushing syndrome
llv05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
llv00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
125100123
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
125100123
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
125100123
09167 Endocrine and metabolic disease
04934 Cushing syndrome
125100123
Enzymes [BR:
llv01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
125100123
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Gene cluster
GFIT
Motif
Pfam:
PDEase_I
PDE8A_N
PDE8
PAS_9
PAS
PAS_3
PAS_4
PAS_8
DUF4194
DHH
Motif
Other DBs
NCBI-GeneID:
125100123
NCBI-ProteinID:
XP_047585979
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All DBs
Position
5:104248054..104532138
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AA seq
892 aa
AA seq
DB search
MGCAPSIHVSQSGVIYCRDSDESNSPRQTTSVSQGPAAPPHGLFVQTDAADVIPPSGASG
PPGAARVRRARAELGSGGSSSSSSSSAGSAAPAATTCRGRRRHCCSSAEAETQTSYTSVK
QVSSAEVRIGPMRLTQDPIQVLLIFAKEDSQSDGFWWACDRAGYRCNIARTPESALECFL
DKHHEIIVIDHRQTRNFDAEAVCRSIRATNPSEHTVILAVVSQALGDREEASVLPLLHAG
FNRRFMENNSIIACYNELIQIEHGEVRSQFKLRACNSVFTALDHCHEAIEITSDDHVIQY
VNPAFERMMGYHKGELLGKELAELPKSDKNRADLLDTINTCIKKGKEWQGVYYARRKSGD
SIQQHVKITPVIGQGGKIRHFVSLKKLCCTTDNNKQLHKIHRDSGDNSQTESHSFRYKNR
RKESIDVKSISSRGSDAPSLQNRRYPSMARIHSMTIEAPITKVINIINAAQENSPVTVAE
ALDRVLEILRTTELYSPQLGTKDEDPHTSDLVGGLMTDGLRRLSGNEYVFTKNVHQSHSH
LAMPITINDVPPCIAQLLDNEESWEFNIFELEAVTHKRPLVYLGLKVFSRFGVCEFLHCS
ETTLRAWLQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAAT
VHDVDHPGRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDSKCNIFKNIDRNHY
RTLRQAIIDMVLATEMTKHFEHVNKFVNSINKPMAAEIEGSDCECNPTGKNFPENQILIK
RMMIKCADVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIPKSQ
ISFIDYFITDMFDAWDAFAHLPALMQHLADNYKHWKTLDDLKCKSLRLPSDS
NT seq
2679 nt
NT seq
+upstream
nt +downstream
nt
atgggctgcgcccccagcatccacgtctcgcagagcggcgtgatctactgccgggactcg
gacgagtccaactcgccccgccagaccaccagcgtgtcgcagggccccgcggccccccca
cacggcctcttcgtccagaccgacgccgccgacgttattcccccgagcggcgcttcggga
ccccccggcgccgcccgcgtccgcagggcccgcgcggagctgggcagcggcgggagcagc
agcagcagcagcagcagcgcgggctccgcagcccccgccgcgaccacctgcaggggccgg
aggcgccactgctgcagcagcgcggaggccgagacccagaccagctacaccagcgtcaag
caggtctcttctgcggaggtgcgcattgggcccatgagactgacgcaggatccaattcag
gttttgctgatctttgcaaaggaagatagtcagagtgatggattctggtgggcctgtgac
agagctggctatagatgcaatattgcacggactccagagtcagcccttgaatgctttcta
gataaacatcatgaaattatcgtaatagatcacagacagacgcgaaactttgacgcagaa
gcggtgtgcaggtcgatccgggccacaaatccttctgagcacacggtgatccttgcggtg
gtttcacaagcattgggtgaccgtgaagaggcctcagtcctccctctcctgcatgcaggc
ttcaacaggagatttatggagaataacagcataattgcttgctataatgaactgattcaa
atagaacatggggaagttcgctcacagttcaaattacgggcctgtaattcagtgtttaca
gccttagaccactgtcatgaagccatagaaattacaagtgatgaccatgtgattcagtac
gtcaacccagcctttgaaagaatgatgggctaccacaaaggcgagctgctgggcaaggag
ctcgccgagctgcccaagagtgataaaaaccgggccgaccttctcgataccatcaacacg
tgcatcaagaaaggcaaggagtggcagggggtttactatgcaagacggaaatccggggac
agcatccaacagcacgtgaagatcactccagtgattggccaaggagggaaaattaggcat
tttgtctccctcaagaaactgtgttgtaccactgacaataataagcagcttcacaagatt
catcgtgattcaggagacaattctcagacagagtctcattcattcagatacaagaacaga
aggaaagagtccattgatgtgaaatcgatatcatctcgaggcagtgatgcaccaagccta
cagaatcgtcgctatccatctatggcaaggatccattccatgaccatcgaggctcccatc
acaaaggttataaatatcatcaatgcagcccaagagaacagccccgtcacagtagcagaa
gccttggacagggttttagaaattctacggaccacagaactgtattcccctcaactgggt
accaaagatgaagatccccacaccagtgatctcgttggaggcctgatgactgatggcttg
agaaggttgtcaggaaacgagtatgtgttcactaagaatgtgcaccagagtcacagccac
cttgcgatgccaataaccatcaacgatgtccccccttgtatcgctcagttacttgataat
gaggaaagttgggagttcaacatctttgaattggaagctgtaacacataaaaggccattg
gtttacctgggcttaaaggtgttttctcggtttggtgtatgtgaatttttacactgctct
gaaactactcttcgagcctggctccaagtgattgaagccaactaccactcctccaatgcc
taccacaactccacccatgccgccgatgtcctgcatgccactgccttcttccttggaaag
gaacgagtgaagggaagcctcgatcagctggacgaggtcgcagcactaattgcggccacg
gtgcacgacgtggatcacccgggaaggaccaactcgttcctttgcaatgcaggcagcgaa
cttgccgtgctctacaatgacaccgctgtcttagagagtcaccacactgccctggctttc
cagctcaccgtcaaggacagcaagtgcaacattttcaagaacatcgacaggaaccattat
cgaacactgcgccaggccattatcgacatggttttagcaacagagatgaccaaacacttt
gaacatgtgaacaaatttgtgaacagcatcaataagccaatggcagctgagattgagggc
agcgactgtgaatgcaaccctactgggaagaactttcctgaaaaccaaatcctgatcaag
cgtatgatgataaagtgtgctgatgtagccaacccatgtcgccccctggacctgtgcatc
gaatgggctgggaggatctctgaggagtattttgcacagactgatgaagagaagagacag
gggctccctgtggtgatgccagtgtttgaccggaatacctgcagcatccccaaatcccag
atctccttcattgactacttcataacagacatgtttgatgcttgggatgcctttgcccat
ctgccagccctgatgcaacatttggctgataactacaaacactggaagacattagatgac
ctcaagtgcaaaagtctgaggcttccatctgatagctaa
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