KEGG   Lutra lutra (Eurasian river otter): 125102908
Entry
125102908         CDS       T08100                                 
Name
(RefSeq) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X1
  KO
K18438  cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:3.1.4.17 3.1.4.35]
Organism
llv  Lutra lutra (Eurasian river otter)
Pathway
llv00230  Purine metabolism
llv01100  Metabolic pathways
llv04024  cAMP signaling pathway
llv05032  Morphine addiction
Brite
KEGG Orthology (KO) [BR:llv00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    125102908
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    125102908
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    125102908
Enzymes [BR:llv01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.17  3',5'-cyclic-nucleotide phosphodiesterase
     125102908
    3.1.4.35  3',5'-cyclic-GMP phosphodiesterase
     125102908
SSDB
Motif
Pfam: PDEase_I GAF GAF_2 GAF_3 SpoVT_C HD DUF7334
Other DBs
NCBI-GeneID: 125102908
NCBI-ProteinID: XP_047590481
LinkDB
Position
6:complement(150731669..151025523)
AA seq 1065 aa
MASPVEPLAPRPHAPLPAAGDEPGSGPGKLRPEPWRGVAGGGSAVGPGRAPEPPGGGRAE
RAAPPRPPPSSAGRASPAGGPGALCSLGSGGWGSARAPFALALSSPVPSSSPSSFYFWPP
PPPPPPSLLPSSSAFHLPVRLPGREGAAAAAAARGGGGGGDAGGGGGGGGQEAAPLSVPP
SSSPRGGGGSGGGRRRRLFLCSALQGLLLPARAGLRLPLGPAARRAGSPGFPGAGGGCPR
PSPGGGGRTPPRPGGAGFALAAASPLLFGSDMEDGPSNNASCFRRLTECFLSPSLTDEKV
KAYLSLHPQVLDEFVSESVSTETVEKWLKRKNNKPEDESAPKEVSRYQDTNMQGVVYELN
SYIEQRLDAGGDNQLLLYELSNVIKIATKADGFALYFLGECNNSLCVFTPPGIKEGKPRL
IPAGPIAQGTTTSAYVAKSRKTLLVEDILGDERFPRGTGLESGTRIQSVLCLPIVTAIGD
LIGVLELYRHWGKEAFCMSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKT
YFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNKELYSDLFDIGEEKEGKPIFKKT
KEIRFSIEKGIAGQVARTGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRGSVI
GVVQMVNKISGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHS
ICTAEEWQDLMRFSLPVRLCKEIELFHFDIGPFESMWPGIFVYMVHRSCGTSCFELEKLC
RFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHGLFTDLERKGLLIACLCHDLDHRG
FSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKA
IIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTA
NDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQIFPPTE
PLLKACRNNLSQWEKVIRGEESAVWISSQPAAHGPSEKLPVKIDD
NT seq 3198 nt   +upstreamnt  +downstreamnt
atggccagccccgtagagccgctcgctccccgcccccacgcccccctgccagcggccggg
gacgagcccggatcgggccccggcaaactccgcccggagccctggcgcggcgttgccggc
ggggggagcgcggtgggcccgggtcgggccccggagccgcccggcggaggccgggccgag
cgcgccgcgcccccgcgcccgcccccctcctccgcaggccgcgccagccccgcggggggc
ccgggcgccctgtgttcgctcggcagcggcggctggggctcagcccgcgctcccttcgcg
ctcgccctctcctcccctgtcccctcctcctctccatcttccttttacttctggccgccg
ccccccccgccccctccttctcttctcccctcctcgtctgcctttcacctccccgtgcgt
ctcccaggaagggagggcgcagcggcggcggcggcggctcgaggaggaggaggcggcggc
gatgctggcggcggcggcggaggaggaggacaagaggcagctcccttgagcgtccctccc
agcagtagtccccgcggcggcggtggcagcggcggcgggcggcggcggcggctcttcctc
tgctccgcgctccagggtttgctgctcccagcccgcgccgggctccggctcccgctcggc
ccggccgcccgccgcgcgggctcccccggcttcccgggtgccggcgggggctgcccccgc
cccagcccaggcggcggcggccgaactccgccgcggcccggaggcgccggcttcgccctc
gctgccgcgtcccccctgctcttcggctccgacatggaagatggaccttctaataacgcg
agctgcttccgaaggttgacggagtgtttcctgagccccagtttgacagatgaaaaagtg
aaggcgtatctttctctccatccccaggtgttagacgagtttgtatctgaaagtgttagc
acagagactgtagaaaaatggctgaagcggaaaaacaacaaacccgaagatgagtcggct
cctaaggaagtcagcaggtaccaagacacgaatatgcagggagttgtatatgaactcaac
agctacatagagcagcggctggacgcaggaggagacaaccagctactcctctatgagttg
agtaacgtcattaaaatagccacaaaagctgatggatttgcactgtatttccttggagag
tgcaataatagtctgtgcgtcttcactccacctggaatcaaagaaggaaaaccccggctc
atccctgctgggcccattgcccagggtaccaccacctctgcctacgtggccaagtccaga
aaaaccttgctagtggaggacatccttggggatgagcgatttccgagaggtactggactg
gagtcggggactcgcatccagtcggtgctctgtttaccgattgtcactgccattggcgat
ttgatcggcgtcctcgagctgtatcggcactggggcaaagaagccttctgtatgagccac
caggaggttgcaacagccaatctcgcctgggcttcagtagcaatacatcaggtgcaggta
tgcagaggccttgctaagcagacggaactgaatgacttcctacttgatgtgtccaagaca
tattttgataacatagtcgcaatagactctctacttgaacacataatgatatatgcaaaa
aatctggtgaatgcagatcgttgtgcacttttccaggtagaccataagaacaaggagtta
tattcagacctttttgatattggagaggaaaaggaaggaaaacctatcttcaagaagacc
aaagagataagattttcaattgagaaaggaattgctggtcaggtagcaagaacgggggaa
gtcctgaacattccagatgcctatgcagacccacgcttcaacagggaagtggacctgtac
acggggtacacgacccggaatatcctgtgcatgcccatcgtgagccgaggcagcgtgatc
ggcgtggtgcagatggtgaacaagatcagcggcagtgccttctcgaagacggacgagaac
aacttcaagatgttcgctgtcttctgcgctttagccttacactgtgccaacatgtaccac
cgaatccgccattccgagtgcatttaccgggtgacgatggagaagctgtcctaccacagc
atctgcacggccgaggagtggcaggacctcatgcgtttcagcctccccgtgcgcctctgc
aaggagatcgaactattccactttgacattggtcctttcgaaagcatgtggcctgggatt
tttgtgtacatggtccatcggtcctgtgggacgtcctgctttgagcttgaaaagttgtgt
cgctttattatgtctgtgaagaagaactaccgccgggtgccgtaccacaactggaagcac
gccgtcacggtggcacactgcatgtacgccatcctgcagaacaaccacgggctcttcacc
gaccttgagcgcaaaggactgctgatcgcgtgcctgtgtcatgacctggaccacaggggt
ttcagcaacagctacctgcagaagttcgaccaccccctggccgcgctctactccacgtcc
accatggagcagcaccacttctcccagaccgtgtccatcctccagctggaagggcacaat
atcttctccaccctgagctccagtgaatatgaacaggtgcttgagatcatccgaaaagcc
atcattgccacagaccttgctctgtactttggaaacaggaaacagttggaagagatgtac
cagaccggatcgctaaaccttaataatcaatcacatagagatcgtgtcattggtctgatg
atgactgcctgtgatctttgctctgtaacaaaactatggccggttacaaaattgacagca
aatgatatatatgcagaattctgggctgagggtgatgagatgaagaagttgggaatacag
cctattcccatgatggacagagacaagaaggatgaggtcccacaaggccagctgggcttc
tacaacgccgtggccatcccctgctacacgacgctcacgcagatcttcccgcccacggag
ccgctcctcaaagcctgcaggaataacctcagccagtgggagaaggtgatccgaggggag
gagagcgccgtgtggatctcatcccagcccgcggcccacgggccctcggagaagctgcct
gtgaagatcgacgactga

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