Lutra lutra (Eurasian river otter): 125103636
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Entry
125103636 CDS
T08100
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
llv
Lutra lutra (Eurasian river otter)
Pathway
llv00230
Purine metabolism
llv01100
Metabolic pathways
llv04927
Cortisol synthesis and secretion
llv04934
Cushing syndrome
llv05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
llv00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
125103636
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
125103636
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
125103636
09167 Endocrine and metabolic disease
04934 Cushing syndrome
125103636
Enzymes [BR:
llv01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
125103636
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Gene cluster
GFIT
Motif
Pfam:
PDEase_I
PDE8A_N
PAS
PDE8
PAS_9
PAS_4
PAS_3
DUF5894
PAS_8
Sina_ZnF
Response_reg
Motif
Other DBs
NCBI-GeneID:
125103636
NCBI-ProteinID:
XP_047591271
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Position
7:complement(4178198..4329480)
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AA seq
830 aa
AA seq
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MGCAPSIHISEGRAVYHGGKEAEDAPGAAAPPPPPAGPKTTASPAARGAGLAEPEPRDGS
GRKVAVADVQFGPMRFHPDQLQVLLVFTKEDNQCNGFCRACEKAGFKCTVTKEAQAVLAC
FLDKHHDIIIIDHRNPRQLDAEALCRSIRSSKLSENTIIIGVVRRTDREESSVMPLIAAG
FTRRYVENPSLMACYNELLQLEFGEVRSQLKLRACNSIFTALEKSQEAIEITSEDRVIQY
ANPAFETTMGYQSGELIGKELAEVPINEKKADLLDTINSCIRIGKEWQGIYHAKKKNGDN
VQQNVKIIPVVGQGGKIRHYVSIIRVCNGSNKAEKITECVQSDPHTDNQSGKHKDRRKSS
LDVRTLASRASEGGSQRRHSSMARIHSMTIEAPITKVINIINAAQESSPMPVTEALDRVL
EILRTTELYSPQFGAKDDDPHANDLVGGLVSDGLRRLSGNEYVLSTKSLQQLPSSVITPI
SLHDVPPRIARAMENEEYWDFNIFELEAATHKRPLIYLGLKMFARFGICEFLNCSETTLR
SWLQVIEANYHSSNPYHNSTHSADVLHATAYFLCKERIKQTLDPVDEVAALIAATIHDVD
HPGRTNSFLCNAGSELAILYNDTAVLESHHAALAFQLTTRDDKCNIFKNMERNDYRTLRQ
GVIDMVLATEMTKHFEHVNKFVNSINKPLAALEADGEVARDEEAVTTMLRTPENRTLVKR
MLIKCADVSNPCRPLEQCIEWAARISEEYFSQTDEEKRQDLPVVMPVFDRNTCSIPKSQI
SFIDYFITDMFDAWDAFVDLPELMQHLDNNFKYWKGLDEMKLRSLRPPPE
NT seq
2493 nt
NT seq
+upstream
nt +downstream
nt
atgggctgcgccccgagcatccacatttccgagggccgggcggtgtaccacggcggcaag
gaggccgaggacgcgccgggagccgccgcgccgccgccgccgcccgccggcccgaagacc
accgcctcgcccgcggcccgcggcgccggcctcgcggagcccgagcctcgcgacggcagc
ggcaggaaggtagcagtagctgacgtgcagttcggcccaatgagatttcatccagatcag
ctccaggtacttttagtgtttaccaaggaagataaccagtgtaatgggttctgcagggca
tgtgaaaaagcggggtttaagtgcacagttaccaaggaggcccaggccgttcttgcctgc
ttcctggacaagcatcatgacatcatcatcattgaccacagaaacccccggcagctggac
gcagaggcgctgtgcaggtctattagatcatcaaaactctctgaaaacacaattattatt
ggtgtagtacgcaggacggatagagaagagtcatctgtgatgcccctcattgccgctggc
tttacgaggaggtatgtggagaaccccagtctcatggcctgctacaacgagctgctccag
ctggagttcggagaggtgcggtcccagctcaaactcagggcttgtaactcaatattcact
gcattagagaaaagtcaagaagcaattgaaattacaagtgaagaccgcgttatacagtat
gcaaatcctgcatttgaaacaaccatgggctatcagtcaggtgaattaataggaaaggag
ttagcagaagtgcctataaatgaaaaaaaagctgatttgctcgatactataaattcgtgc
atcaggataggcaaggagtggcaagggatctaccatgccaagaagaaaaatggagataat
gtgcaacaaaatgtgaagataatacctgtcgttggacagggaggaaaaattagacactat
gtgtccattatcagagtgtgcaatggcagcaataaggctgagaaaataactgaatgtgtt
cagtctgaccctcatacagataatcagtcaggcaaacacaaagacagaaggaagagctcg
ctagatgtcagaactcttgcttctcgagcaagtgaaggtggcagccagagacgacactcc
tccatggcccggatacattccatgacgatcgaggcgcccatcaccaaggtcatcaacatt
atcaatgctgcccaggaaagcagccccatgcctgtgacagaagccttagaccgtgtgctg
gaaattctgagaaccactgagttatactcaccgcagtttggtgctaaggatgacgatcct
catgccaacgacctcgttggaggcttagtgtctgatggtttgcgaagactgtccgggaat
gagtatgttctttcaacaaaaagccttcagcagctgcccagcagtgtgatcacccccatc
tcccttcacgatgtccccccgcggatcgcgcgggccatggagaacgaggagtactgggac
ttcaatatttttgaactggaggccgccacacataagaggcctttgatttatcttggtctc
aaaatgttcgctcgcttcggaatctgtgaattcttgaactgctccgagacgacgctgcga
tcgtggttgcaggtcattgaagccaattaccactcttccaacccctaccacaactcgaca
cactctgccgacgtgcttcacgccactgcctactttctgtgcaaagagaggataaagcaa
actttagatccggtcgacgaggtcgcggccctcatcgcagccaccatccacgacgtggac
caccccgggagaaccaactcattcctgtgcaatgctggaagcgagctggccattttgtat
aatgacactgctgtgctggagagccaccacgcagccttggccttccagctgaccacccga
gatgacaaatgcaatatcttcaagaatatggagaggaacgactaccggacgctgcgtcag
ggggttatcgacatggtcttagccacagaaatgaccaagcacttcgagcacgtcaacaaa
tttgtcaacagcatcaacaagcccctggcagcactcgaagcagatggggaagtggctaga
gatgaagaagccgtgaccaccatgctcaggaccccagagaaccggacactggttaagcgg
atgctgatcaagtgcgcggatgtgtccaacccctgccggcccctggagcagtgcattgag
tgggccgcacgcatctccgaagaatacttttctcagacggatgaggagaagcggcaggac
ttacccgtggtgatgccggtttttgacagaaacacctgcagcatccccaagtcccagatt
tccttcatcgactacttcatcacggacatgtttgatgcttgggacgcctttgtagacctg
cctgagttaatgcagcatcttgacaacaactttaaatactggaaaggactggacgaaatg
aagctgcggagcctccggccgccccccgagtag
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