Lutra lutra (Eurasian river otter): 125105653 Help Entry 125105653         CDS       T08100                                  Name (RefSeq) hypoxia-inducible factor 1-alpha   KO K08268   hypoxia-inducible factor 1 alpha Organism llv  Lutra lutra (Eurasian river otter) Pathway llv04066   HIF-1 signaling pathway llv04137   Mitophagy - animal llv04140   Autophagy - animal llv04148   Efferocytosis llv04659   Th17 cell differentiation llv04919   Thyroid hormone signaling pathway llv05167   Kaposi sarcoma-associated herpesvirus infection llv05200   Pathways in cancer llv05205   Proteoglycans in cancer llv05208   Chemical carcinogenesis - reactive oxygen species llv05211   Renal cell carcinoma llv05230   Central carbon metabolism in cancer llv05231   Choline metabolism in cancer llv05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:llv00001]  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     125105653  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     125105653    04137 Mitophagy - animal     125105653    04148 Efferocytosis     125105653  09150 Organismal Systems   09151 Immune system    04659 Th17 cell differentiation     125105653   09152 Endocrine system    04919 Thyroid hormone signaling pathway     125105653  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     125105653    05205 Proteoglycans in cancer     125105653    05208 Chemical carcinogenesis - reactive oxygen species     125105653    05230 Central carbon metabolism in cancer     125105653    05231 Choline metabolism in cancer     125105653    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     125105653   09162 Cancer: specific types    05211 Renal cell carcinoma     125105653   09172 Infectious disease: viral    05167 Kaposi sarcoma-associated herpesvirus infection     125105653  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03000 Transcription factors [BR:llv03000]     125105653 Transcription factors [BR:llv03000]  Eukaryotic type   Basic helix-loop-helix (bHLH)    Factors with PAS domain     125105653 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  bHLH_HIF1A PAS_3 PAS_11 HIF-1a_CTAD PAS HIF-1 PAS_9 PAS_4 HLH DDRGK Motif Other DBs NCBI-GeneID:  125105653 NCBI-ProteinID:  XP_047595248 LinkDB All DBs Position 7:108789726..108831050 Genome browser AA seq 823 aa AA seqDB search MEGAGGANDKKKISSERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASVM RLTISYLRVRKLLDAGDLDIEDEMKAQMNCFYLKALDGFVMVLTDDGDMIYISDNVNKYM GLTQFELTGHSVFDFTHPCDHEEMREMLTHRNGLVKKGKEQNTQRSFFLRMKCTLTSRGR TMNIKSATWKVLHCTGHIHVYDTNSNQSQCGYKKPPMTCLVLICEPIPHPSNIEIPLDSK TFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQV TTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIIQHDLIFSLQQTECV LKPVESSDMKMTQLFTKVESEDTSSLFDKLKKEPDALTLLAPAAGDTIISLDFGSNDTET DDQQLEEVPLYNDVMLPSSNEKLQNINLAMSPLPASETPKPLRSSADPALNQEVALKLEP NPESLELSFTMPQIQDQPASPSDGSTRQSSPEPNSPSEYCFDVDSDMVNEFKLELVEKLF AEDTEAKNPFSTQDTDLDLEMLAPYIPMDDDFQLRSFDQLSPLESSSTSPQSASTITVFQ PTQMQEPPVTTTSTTATTDELKTVTKDGIEDIKILIASPSPTHVPKVTTSTTTSPYSDTG SRTASPNRAGKGVIEQTEKSHPRSPNVLSVTLSQRTTIPEEELNPKILALQNAQRKRKIE HDGSLFQAVGIGTLLQQPDDRATTTSLSWKRVKGCKSSEHSGMEQKTIILIPSDLACRLL GQSMDESGLPQLTSYDCEVNAPIQGSRNLLQGEELLRALDQVN NT seq 2472 nt NT seq  +upstreamnt  +downstreamnt atggagggcgccggcggcgcgaacgacaagaaaaagataagttctgaacgtcgaaaagaa aagtctagagatgcagctagatctcggcgaagtaaagagtccgaagtgttttatgagctt gctcatcagttgccactcccccataatgtgagctctcatcttgataaggcttctgttatg aggctgaccatcagctatttgcgtgtaaggaaacttctggatgctggtgatttagatatt gaagatgaaatgaaagcacagatgaattgcttttatttgaaagctctggatggttttgtt atggtactcacagatgatggtgacatgatttatatttctgataatgtgaacaaatacatg ggattgactcagtttgaactaactggacacagtgtgtttgattttactcatccatgtgac catgaggaaatgagagaaatgcttacacacagaaatggccttgtgaaaaagggtaaagag cagaatacacagcgaagcttttttctcagaatgaagtgtaccctaactagccgggggaga actatgaacataaagtcagcaacttggaaggtacttcactgcacgggccatattcatgtc tacgatactaatagtaaccaatctcagtgtgggtataagaaaccacctatgacgtgcttg gtgctgatttgtgaacccattcctcatccatcaaatattgaaattcctttagatagcaag acttttctcagtcgtcacagtctggatatgaaattttcttattgtgatgaaagaattact gaattgatgggatatgagccagaagaacttttgggccgctcaatttatgaatattatcat gctttggactctgaccatctgaccaaaactcatcatgatatgtttactaaaggacaagtc accacaggacagtacaggatgcttgccaaaagaggtggatatgtctgggttgaaactcaa gcaactgtcatatataacactaagaattctcaaccacagtgcattgtatgtgtaaattat gtggtgagtggtattattcagcacgacttgattttctcccttcaacaaacagaatgtgtc ctcaaaccagttgaatcttcagatatgaaaatgactcagctattcaccaaagttgaatca gaagatacaagtagtctctttgataaacttaagaaggaacctgatgctttaactttgctg gccccagctgctggagacacaatcatatctttagatttcggcagcaatgacacagaaact gatgaccagcaacttgaggaagttccattgtataatgatgtaatgctcccctcatccaat gaaaaattacagaatataaatttggcaatgtctccattacctgcttctgaaactccaaag ccacttcgaagtagtgctgaccctgcactcaatcaagaagttgcgttaaaattagagcca aatccagagtcactggaactgtcttttactatgccccagattcaagatcagccagctagt ccttctgatggaagcactagacaaagttcacctgagcctaacagtcccagtgaatattgt tttgatgtggatagtgatatggtcaatgaatttaagctggaattggtagagaaacttttt gctgaagacacagaagcaaagaatccattttccacccaggacactgatttagacctggag atgttagctccttatatcccaatggatgatgacttccagttacgttccttcgatcagctg tcgccactggaaagcagttctacaagccctcaaagtgcaagcacaattacagtattccag ccgactcaaatgcaggaacctcctgttaccactaccagtaccactgctaccactgatgaa ttaaaaacagtgacaaaagatggtatagaagacattaaaatattgattgcatccccatct cctactcacgtacctaaagtaactactagtaccacaacatcaccttacagtgatactgga agtcggacagcctcaccaaacagagcaggaaaaggagtcatagaacaaacagaaaaatct catccaagaagccctaatgtgttatctgtcactttgagtcaaagaaccaccattcctgag gaagaactaaatccaaagatactagctttgcagaatgctcagagaaagcgaaaaatagaa catgatggttcactttttcaagcagtaggaattggaacattattacagcagccagacgat cgtgcaactactacgtcactttcttggaaacgcgtaaaaggatgcaaatctagtgaacac agtggaatggagcaaaagacaattattttaataccctctgatttagcatgtagactgctg gggcaatcaatggatgagagtggattaccacaactgaccagttatgattgtgaagttaat gctcctatacaaggcagcagaaacctactgcagggtgaagaattactcagagctttggat caagttaactga

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