Lutra lutra (Eurasian river otter): 125107116
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Entry
125107116 CDS
T08100
Name
(RefSeq) inositol 1,4,5-trisphosphate receptor type 2 isoform X1
KO
K04959
inositol 1,4,5-triphosphate receptor type 2
Organism
llv
Lutra lutra (Eurasian river otter)
Pathway
llv04020
Calcium signaling pathway
llv04022
cGMP-PKG signaling pathway
llv04070
Phosphatidylinositol signaling system
llv04114
Oocyte meiosis
llv04210
Apoptosis
llv04218
Cellular senescence
llv04270
Vascular smooth muscle contraction
llv04371
Apelin signaling pathway
llv04380
Osteoclast differentiation
llv04540
Gap junction
llv04611
Platelet activation
llv04621
NOD-like receptor signaling pathway
llv04625
C-type lectin receptor signaling pathway
llv04720
Long-term potentiation
llv04723
Retrograde endocannabinoid signaling
llv04724
Glutamatergic synapse
llv04725
Cholinergic synapse
llv04726
Serotonergic synapse
llv04728
Dopaminergic synapse
llv04730
Long-term depression
llv04750
Inflammatory mediator regulation of TRP channels
llv04912
GnRH signaling pathway
llv04915
Estrogen signaling pathway
llv04918
Thyroid hormone synthesis
llv04921
Oxytocin signaling pathway
llv04922
Glucagon signaling pathway
llv04924
Renin secretion
llv04925
Aldosterone synthesis and secretion
llv04927
Cortisol synthesis and secretion
llv04928
Parathyroid hormone synthesis, secretion and action
llv04929
GnRH secretion
llv04934
Cushing syndrome
llv04935
Growth hormone synthesis, secretion and action
llv04970
Salivary secretion
llv04971
Gastric acid secretion
llv04972
Pancreatic secretion
llv05010
Alzheimer disease
llv05012
Parkinson disease
llv05017
Spinocerebellar ataxia
llv05020
Prion disease
llv05022
Pathways of neurodegeneration - multiple diseases
llv05163
Human cytomegalovirus infection
llv05167
Kaposi sarcoma-associated herpesvirus infection
llv05170
Human immunodeficiency virus 1 infection
llv05205
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:
llv00001
]
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
125107116
04020 Calcium signaling pathway
125107116
04070 Phosphatidylinositol signaling system
125107116
04022 cGMP-PKG signaling pathway
125107116
09140 Cellular Processes
09143 Cell growth and death
04114 Oocyte meiosis
125107116
04210 Apoptosis
125107116
04218 Cellular senescence
125107116
09144 Cellular community - eukaryotes
04540 Gap junction
125107116
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
125107116
04621 NOD-like receptor signaling pathway
125107116
04625 C-type lectin receptor signaling pathway
125107116
09152 Endocrine system
04922 Glucagon signaling pathway
125107116
04929 GnRH secretion
125107116
04912 GnRH signaling pathway
125107116
04915 Estrogen signaling pathway
125107116
04921 Oxytocin signaling pathway
125107116
04935 Growth hormone synthesis, secretion and action
125107116
04918 Thyroid hormone synthesis
125107116
04928 Parathyroid hormone synthesis, secretion and action
125107116
04924 Renin secretion
125107116
04925 Aldosterone synthesis and secretion
125107116
04927 Cortisol synthesis and secretion
125107116
09153 Circulatory system
04270 Vascular smooth muscle contraction
125107116
09154 Digestive system
04970 Salivary secretion
125107116
04971 Gastric acid secretion
125107116
04972 Pancreatic secretion
125107116
09156 Nervous system
04724 Glutamatergic synapse
125107116
04725 Cholinergic synapse
125107116
04728 Dopaminergic synapse
125107116
04726 Serotonergic synapse
125107116
04720 Long-term potentiation
125107116
04730 Long-term depression
125107116
04723 Retrograde endocannabinoid signaling
125107116
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
125107116
09158 Development and regeneration
04380 Osteoclast differentiation
125107116
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
125107116
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
125107116
05163 Human cytomegalovirus infection
125107116
05167 Kaposi sarcoma-associated herpesvirus infection
125107116
09164 Neurodegenerative disease
05010 Alzheimer disease
125107116
05012 Parkinson disease
125107116
05017 Spinocerebellar ataxia
125107116
05020 Prion disease
125107116
05022 Pathways of neurodegeneration - multiple diseases
125107116
09167 Endocrine and metabolic disease
04934 Cushing syndrome
125107116
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
llv04040
]
125107116
Ion channels [BR:
llv04040
]
Ligand-gated channels
IP3 receptor
125107116
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ins145_P3_rec
RYDR_ITPR
MIR
RIH_assoc
Ion_trans
Mis12
Sec2p
DUF2207_C
DUF1798
Motif
Other DBs
NCBI-GeneID:
125107116
NCBI-ProteinID:
XP_047597795
LinkDB
All DBs
Position
8:complement(76117163..76608244)
Genome browser
AA seq
2701 aa
AA seq
DB search
MSDKMSSFLYIGDIVSLYAEGSVNGFISTLGLVDDRCVVHPEAGDLTNPPKKFRDCLFKV
CPMNRYSAQKQYWKAKQAKQGNHTEAALLKKLQHAAELEQKQNESENKKLLGEIVKYSNV
IQLLHIKSNKYLTVNKRLPALLEKNAMRVSLDAAGNEGSWFYIHPFWKLRSEGDNIVVGD
KVVLMPVNAGQPLHASNIELLDNRGCKEVNAVNCNTSWKITLFMKYSSYREDVLKGGDVV
RLFHAEQEKFLTCDEYEKKQHIFLRTTLRQSATSATSSKALWEIEVVHHDPCRGGAGQWN
SLFRFKHLATGNYLAAELNPDYRDAQNEGKNMRDGDLPTSKKKRQAGEKIMYTLVSVPHG
NDIASLFELDATTLQRADCLVPRNSYVRLRHLCTNTWVTSTSIPIDTDEERPVMLKIGTC
QTKEDKEAFAIVSVPLSEVRDLDFANDANKVLATTVKKLENGTITQNERRFVTKLLEDLI
FFVADVLNNGQEVLDVVITKPNRERQKLMREQNILAQVFGILKAPFKEKAGEGSMLRLED
LGDQRYAPYKYMLRLCYRVLRHSQQDYRKNQEYIAKNFCVMQSQIGYDILAEDTITALLH
NNRKLLEKHITAKEIETFVSLLRRNREPRFLDYLSDLCVSNTTAIPVTQELICKFMLSPG
NADILIQTKLVSMQVDNPMESSILSDDIDDEEVWLYWIDSNKEPHGKAIRHLAQEAKEGT
KADLEVLTYYRYQLNLFARMCLDRQYLAINQISTQLSVDLILRCVSDESLPFDLRASFCR
LMLHMHVDRDPQESVVPVRYARLWTEIPTKITIHEYDSITDSSRNDMKRKFALTMEFVEE
YLKEVVNQPFPFGDKEKNKLTFEVVHLARNLIYFGFYSFSELLRLTRTLLAILDIVQVPM
SSYFERLSKFQDGGNNVMRTIHGVGEMMTQMVLSRGSIFPMSVPDVQPSIHPSKQGSPIE
HEDVTVMDTKLKIIEILQFILSVRLDYRISYMLSIYKKEFGENNENTETSASGSPDTVLP
SAIVPDIDEIAAQAETMFAGRKEKNPVQLDDEGGRTFLRVLIHLIMHDYPPLLSGALQLL
FKHFSQRAEVLQAFKQVQLLVSNQDVDNYKQIKADLDQLRLTVEKSELWVEKSSSYENGE
MGESQVKGGEEPIEDSSILSPVQDGTRKPQIDSNKSNNYWIVKEILIRLSKLCVQNKKCR
NQHQRLLKNMGAHSVVLDLLKIPYEKNDEKMNEVMNLAHTFLQNFCRGNPQNQVLLHKHL
NLFLTPGLLEAETMRHIFMNNYHLCNEISERVVQHFVHCIETHGRHVEYLRFLQTIVKAD
GKYVKKCQDMVMTELINGGEDVLIFYNDRASFPILLHMMCSERDRGDESGPLAYHITLVE
LLAACTEGKNVYTEIKCNSLLPLDDIVRVVTHDDCVPEVKIAYVNFVNHCYVDTEVEMKE
IYTSNHIWKLFENFLVDMARVCNTTTDRKHADTFLEKCVTESIMNIVSGFFNSPFSDNST
SLQTHQPVFIQLLQSAFRIYNCTWPNPAQKSSVESCIRTLAEVAKNRGIAIPVDLDSQVN
TLFLKSHSNMVQRAAMGWRLSARSGPRFKEALGGPSWDYRNIIEKLQDVVASLEQQFSPM
MQAEFSVLVDVLYSPELLFPEGSDARIRCGAFMSKLINHTKKLMEKEEKLCIKILQTLRE
MLEKKDSFVEEGNTLRKILLNRYFKGDYGVGPNGHLSGTYCKSAQGAGSFSGQDSDKMGI
SMSDIQCLLDKEGASELVIDVIVNTKNDRIFSEGILLGIALLEGGNTQTQYSFYQQLHEQ
KKSEKFFKVLYDRMKAAQKEIRSTVTVNTIDLGNKKRDDDNELMTSGPRMRVRDSSLLLK
EGMKGQLTEASSATSKAYCAYRREMDPEIDIMCAGSEAGNTEEKSAEEVTMSPAIAIMQP
ILRFLQLLCENHNRELQNFLRNQNNKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEK
NVVLVNQTLESLTEYCQGPCHENQTCIATHESNGIDIIIALILNDINPLGKYRMDLVLQL
KNNASKLLLAIMESRHDSENAERILFNMRPRELVDVMKNAYNQGLECDHGEDEGGDDGVS
PKDVGHNIYILAHQLARHNKLLQQMLKPGSDPDDGDEALKYYANHTAQIEIVRHDRTMEQ
IVFPVPNICEYLTRESKCRVFNTTERDEQGSKVNDFFQQTEDLYNEMKWQKKIRNNPALF
WFSRHISLWGSISFNLAVFINLAVALFYPFGDDGDEGTLSPLFSVLLWIAVAVCTSVLFF
FSKPVGIRPFLVSIMLRSIYTIGLGPTLILLGAANLCNKIVFLVSFVGNRGTFTRGYRAV
ILDMAFLYHVAYVLVCMLGLFVHEFFYSFLLFDLVYREETLLNVIKSVTRNGRSIILTAV
LALILVYLFSIIGFLFLKDDFTMEVDRLKNRTPVTGSNEVPTMTLTSTMETCEKDSCSPT
IPASNTADEEYEDGIERTCDTLLMCIVTVLNQGLRNGGGVGDVLRRPSKDEPLFAARVVY
DLLFYFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVSFE
EHIKSEHNMWHYLYFLVLVKVKDPTEYTGPESYVAQMIVEKNLDWFPRMRAMSLVSNEGD
GEQNEIRNLQEKLESTMSLVKQLSAQLAELKEQMTEQRKNKQRLGFLGSNTPHVNHHMPS
H
NT seq
8106 nt
NT seq
+upstream
nt +downstream
nt
atgtctgataaaatgtccagcttcctctacataggggacatcgtgtccctgtacgcggag
ggctcggtcaacggcttcatcagcactctggggttagtggatgacagatgtgtggtgcac
ccagaagcgggagacctcaccaatcctcccaagaaattcagagactgcctctttaaggtg
tgccctatgaaccgatattctgcccagaaacaatactggaaagctaagcaagccaaacag
gggaaccacacagaggcagccttgctgaagaaattacagcatgctgcagaactggaacaa
aaacaaaatgaatcagagaataagaaactgttgggagaaattgtgaaatacagtaatgtt
atacaactgctgcatataaaaagcaacaagtatctgactgtcaacaagagattacctgct
ttactggagaagaatgccatgcgtgtgtccttggatgctgcaggaaatgaagggtcttgg
ttttatattcatcccttctggaagctgagaagtgagggtgacaatattgtcgtgggtgat
aaagttgttctgatgcctgtgaacgcgggacagccgctgcacgccagcaacatagagctt
ctcgataatcgagggtgcaaggaggtgaatgctgttaattgcaacactagctggaaaatc
actttattcatgaaatatagttcctatcgagaggatgtactaaaaggaggtgatgttgtt
agactgtttcatgcagaacaagagaagtttctgacttgtgatgaatatgagaagaaacag
cacattttccttcggacaaccttgcgtcaatcagccacttctgctaccagttctaaagcg
ctctgggaaatagaggtcgttcaccatgacccatgccgcgggggtgctggacaatggaac
agcttgttcagatttaaacaccttgcaactgggaactatttagctgcagagcttaatcct
gattatcgagatgctcaaaatgaaggaaaaaatatgagagatggagatcttccaacttca
aagaagaaacgccaggccggggagaagatcatgtatactttagtctcagtcccacatgga
aatgacattgcatccctgtttgagctggatgccacaactcttcagagagctgactgcctg
gttccaaggaactcttatgttcggttgagacatttatgtaccaacacatgggtaacaagt
actagtatacccatagacacagatgaagagagacctgttatgttgaagattggaacttgc
caaacaaaagaagataaagaagcatttgccattgtgtctgtcccgttgtctgaggtccga
gacttagactttgccaatgatgcaaataaagtgctggcgaccacagttaaaaagctggaa
aatggtacaataactcagaatgaaaggaggtttgtaaccaaattattggaagacctcatc
ttctttgtggctgatgtacttaataatggacaagaagttctggatgtggttatcactaag
ccaaaccgagaacgtcaaaaattaatgagggaacaaaacatattggcacaggtatttggg
attctcaaagcaccctttaaagagaaggcaggagaaggctcaatgctgagacttgaagat
ctgggggaccaaagatacgctccctacaagtatatgctgaggctgtgttaccgtgtgctg
agacattcacaacaggactatcggaaaaaccaggaatatattgctaagaatttctgtgtc
atgcagtcccagattggctatgatattttggcagaagataccatcacagctttgttgcac
aacaacagaaaactactagagaaacatatcacagcaaaagaaatagaaacatttgtcagt
ttactcaggagaaatcgtgagccaaggtttttggattatttgtcagatctatgtgtttct
aataccactgctatacctgtaactcaagaactcatctgtaaatttatgctgagcccaggc
aatgcagacattctcattcaaactaagctggtttcaatgcaagtagacaaccccatggag
agctccatcctctcggatgacattgatgatgaagaagtttggctctactggattgacagc
aataaggaacctcatggcaaagctatcaggcaccttgctcaagaagcaaaagaaggcacc
aaagctgatttggaagttcttacctattataggtaccagctaaacctctttgcaaggatg
tgcttggatcgccagtatctggccataaaccagatttctacgcagctctctgtggatttg
atcctgcggtgtgtgtcggatgagagcctgccctttgacctccgagcgtctttttgtcgc
ctcatgctccacatgcatgttgaccgggatccccaggaatccgtggtgcctgttcgctac
gcccggctgtggaccgaaattcctacaaagatcacaattcatgaatatgattctataaca
gactcttccagaaatgatatgaagaggaaatttgcactgacaatggaatttgttgaagaa
tacttgaaagaagttgttaatcagccctttccttttggggataaagaaaaaaacaaactg
acatttgaggtggtccacttggctcggaatcttatatactttggattttatagtttcagc
gaattgttaagactaacaagaacacttctggctatcctagatattgtacaggtccccatg
tcatcgtattttgaaagactaagcaaatttcaagatggtggaaacaatgtcatgagaacc
atccatggggtgggagagatgatgacccaaatggtactcagtcgaggctctatcttcccc
atgagtgtgcctgacgttcagcccagcatccaccccagcaagcaggggagccccatagag
catgaagatgtgaccgtgatggacaccaaactgaagattattgagattctgcagtttatc
ctgagtgtcagactagattataggatctcgtatatgctgtcaatatacaagaaggaattt
ggagagaacaatgagaacacggaaacgtctgccagtggttctccagatacggtactacca
tcagctattgttcctgatatagatgaaattgcagcccaggcagaaactatgtttgctgga
agaaaggagaaaaatccagttcaacttgatgatgaaggaggcaggacctttctacgcgtc
ctcattcatctgatcatgcatgactaccctcctttgctctcaggagccctacagctactg
ttcaagcacttcagccagagagcagaagtcttacaggcgtttaaacaggtgcaattgctg
gtgtccaatcaagatgtagataactacaagcaaatcaaggcagatctagaccagcttcga
ctaacggtggaaaaatctgagttatgggttgagaagagcagcagctatgaaaatggagaa
atgggtgaaagtcaagtaaaaggtggtgaagaacccattgaggactcaagcattttaagt
ccagtgcaggatggaacaaggaaacctcagattgacagcaataagagcaataactactgg
attgtgaaggagattttgatcagactaagtaaactctgtgtccagaataaaaagtgtcgg
aatcagcatcaacgattactgaaaaatatgggagctcattcggtggtgttggatcttctg
aagataccctatgaaaagaatgatgaaaagatgaacgaagtgatgaatctggcccacacc
ttcttgcagaatttctgccggggaaatccacagaaccaagttctccttcataaacatctg
aatttgtttttaactcccggtctcctggaagcagaaaccatgaggcacatcttcatgaac
aattaccatctctgcaatgagatcagcgagagagttgtgcaacactttgtgcattgcatt
gagacacacggccgccacgtggagtacctgaggtttctgcaaacgattgtaaaagcagat
ggtaaatatgtgaagaaatgccaggatatggtaatgacagagttgataaatgggggtgaa
gatgtgctgatattttacaatgatagagcatcatttcccatccttctccatatgatgtgt
tcagagagagaccgaggggatgagagtggccccttagcctaccacatcaccctggtggag
ctgctggcagcatgcacagaggggaagaacgtctacactgaaatcaagtgcaattccctt
ctgcccttggacgacatagtgagggtggtgacccatgatgactgcgtccccgaggttaaa
attgcttatgtgaattttgttaatcactgttatgtggacactgaagtggaaatgaaagaa
atctacacgagtaaccacatttggaaattatttgagaacttcttggtggacatggcaagg
gtttgcaacacaaccacggacaggaaacacgcagacaccttcctggagaagtgtgtcact
gagtcaataatgaacattgtgagcggcttctttaattcccccttttcagacaacagtacc
agcctccagacacatcagccagtttttattcagctgctgcaatctgccttcagaatttac
aattgtacctggccaaacccagcgcagaagtcctccgtggagtcctgtatcagaactctg
gcagaagtggcaaagaatcgtgggattgctattccggtggatttggacagccaagtcaat
acccttttcctgaagagccattccaatatggtgcagagagctgccatgggttggagacta
tctgctcgctctggaccacgctttaaggaagctcttggagggccttcttgggattataga
aatattattgaaaagttacaggatgtagtggcctcgttggagcaacagttcagcccaatg
atgcaagctgaattctccgtgttggttgatgtgttgtacagtccggaactactgttcccc
gaggggagtgatgcaagaataagatgtggtgccttcatgtccaagttgattaatcataca
aagaaactaatggagaaagaagaaaagctgtgcattaaaattcttcagactttacgagaa
atgctagagaagaaagacagctttgtggaagagggtaacacattaagaaaaatactcctg
aatcgctactttaaaggagactatggagttggtccgaatggacacctctctgggacctac
tgcaaatctgcacaaggggcagggagcttttctggacaagattcagataagatggggata
tcaatgtcagatattcagtgtctgctggataaagaaggtgcatctgaacttgtcattgat
gttatagtgaacaccaaaaatgacaggattttttcagaaggcattttacttggcattgcc
ttgctcgaaggaggaaatacacagactcagtattccttctaccagcagttgcacgaacaa
aaaaagtcagaaaaattcttcaaagttctctatgaccgaatgaaggctgctcagaaagag
ataagatcaacagtgacagttaataccatagacttaggtaacaaaaaaagggatgatgac
aatgaattgatgacatctggtccacgaatgagagtaagagattcatcattacttttgaaa
gagggaatgaaagggcaattaacagaagcttcttcagcgacatccaaagcatactgtgcc
taccgaagggaaatggatccagaaatagacattatgtgtgcaggatcggaagcgggaaac
actgaggaaaagtctgcggaggaagtcacgatgagccctgcgatcgccatcatgcagccc
atactacggtttcttcagctgctgtgtgagaatcacaaccgggaactgcagaacttcttg
aggaatcaaaacaacaaaacaaattataacctcgtctgtgaaacccttcagtttttggac
tgcatctgtggaagtaccacgggtggcctgggcctgttgggtctctacatcaatgagaag
aacgtagtactggtcaaccagactctggagagcttgacggaatattgccagggcccatgc
catgaaaatcagacttgtattgctactcatgaatcaaatgggattgatatcatcattgct
ttgattctaaatgacataaaccctctgggtaaatatcgaatggatctggtgctccaacta
aagaacaatgcctctaagcttttgctggccattatggaaagcagacatgacagcgagaac
gcggaaagaattctttttaacatgagacccagggaactggtggatgtgatgaagaatgcc
tataaccaaggactggaatgtgaccatggggaggatgagggcggagatgatggtgtttcc
ccaaaagatgttggacacaatatctatatcctggcccatcagttggctcgtcacaacaaa
ctcttacagcaaatgctcaaaccaggatcagatccagatgacggggatgaagctttaaaa
tattacgccaaccacactgcacagattgagattgttcggcatgataggacgatggagcaa
atagtttttcctgtccccaatatatgtgaataccttacacgagaatccaagtgccgtgtg
ttcaatacaactgaaagggatgaacaaggaagtaaagtgaatgactttttccagcaaaca
gaagatctctacaatgaaatgaagtggcagaagaaaatcaggaataaccctgcactgttc
tggttctcgaggcacatatccctctgggggagcatttccttcaacttggctgtgttcatc
aatttagctgttgctctcttctatccatttggggatgacggagatgaaggtacactttct
ccgttgttctccgttcttctttggatagccgtcgctgtctgcacatctgtgctgtttttc
ttctccaagcctgtgggtattcggccatttcttgtgtcaataatgctcaggtcgatatat
acaataggtcttgggcctacgttaatacttcttggtgcagctaatctttgtaataaaatc
gtatttctggtgagtttcgtgggcaatcgtggcaccttcacccgaggctaccgagcagta
atcctggatatggcctttctctaccacgtggcgtacgtcctggtttgcatgctgggtctc
tttgtccatgaattcttctatagcttcctgctttttgatttggtgtacagagaagagact
ctgcttaatgtcataaagagtgtcacgcggaatggccgctccatcattctaactgccgtc
ctggcgctcatcctcgtctacctgttttccattattgggttccttttcctgaaggacgac
ttcacgatggaggtggaccggctgaaaaacagaactcctgtgacaggtagtaacgaagtt
cctactatgactttaacttcaacgatggaaacatgtgaaaaggacagctgctcacccaca
ataccggcttcaaatacagctgatgaagagtatgaggatggaattgaaaggacatgtgac
actctcctcatgtgtatcgtcactgtcctgaaccagggccttcggaatggtggcggtgtg
ggagacgttctcaggaggccatcgaaagatgagcctttgtttgctgcccgagtggtgtat
gaccttcttttctatttcattgtcatcattattgtcctaaacttgatttttggtgttatc
attgatacttttgctgatctcagaagtgaaaaacagaaaaaagaagagattctaaagaca
acctgcttcatctgtggacttgagagagacaagtttgataataaaacggtttcatttgag
gagcacatcaagtcagaacacaatatgtggcattatttgtacttcctcgtcctggtgaag
gttaaagacccaactgaatacactggacctgaaagttacgtggctcagatgatcgtggag
aagaatttagactggtttcctcggatgcgagccatgtccctcgttagcaatgaaggtgat
ggtgagcaaaatgagattcggaacctgcaggagaagttggaatccaccatgagcttggtc
aaacagctgtcggcacagctggcagagctcaaagagcagatgacagaacaaaggaagaat
aagcagagactgggctttctcggatcaaacacaccccatgtgaaccatcacatgccatca
cactga
DBGET
integrated database retrieval system
