Lutra lutra (Eurasian river otter): 125110272
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Entry
125110272 CDS
T08100
Name
(RefSeq) beta-secretase 1 isoform X1
KO
K04521
beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:
3.4.23.46
]
Organism
llv
Lutra lutra (Eurasian river otter)
Pathway
llv05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
llv00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
125110272
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
llv01002
]
125110272
Enzymes [BR:
llv01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.46 memapsin 2
125110272
Peptidases and inhibitors [BR:
llv01002
]
Aspartic peptidases
Family A1: pepsin family
125110272
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Gene cluster
GFIT
Motif
Pfam:
Asp
TAXi_C
TAXi_N
Motif
Other DBs
NCBI-GeneID:
125110272
NCBI-ProteinID:
XP_047603329
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All DBs
Position
10:complement(13585381..13609363)
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AA seq
501 aa
AA seq
DB search
MAQALPWLLLWMGWGVLPARCSQPGIRLPLRSGLGAPPLGLRLPRETVEEPEEPSRRGSF
VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST
YRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGIL
GLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGI
DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK
VFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRIT
ILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSAC
HVHDEFRTAAVEGPFITPDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQW
RCLRCLRHQHDDFADDISLLK
NT seq
1506 nt
NT seq
+upstream
nt +downstream
nt
atggcccaagcgctgccctggctcctgctgtggatgggctggggagtgctgcccgcccgc
tgctcccagcccggcatccggctgccccttcgaagcgggctgggggcgcccccccttggg
ctgcggctgccccgggagacggtggaggagcccgaggagcccagccggaggggcagcttt
gtggagatggtggacaacctgaggggcaagtccggtcagggctactacgtggaaatgacc
gtgggcagccccccgcagacgctcaacatcctcgtggacacaggcagcagtaactttgcg
gtgggggctgccccccaccctttcctgcatcgctactaccagaggcagctgtccagcacg
taccgggacctccggaagggcgtgtatgtgccctacacccagggcaagtgggagggggag
ctgggcaccgacctggtgagcatcccccacggccccaacgtcactgtgcgcgccaacatc
gctgccatcacggaatcagacaagttcttcatcaatggctccaactgggagggcatcctg
gggctggcctatgctgagatcgccaggcccgatgactccctggagccgttctttgactcc
ctggtaaagcagacccacgttcccaacctcttctccctgcagctctgtggcgcaggcttc
ccgctcaaccagtcggaagtgctagcctcagttggagggagcatgatcatcgggggtatc
gaccactcactgtacacgggcagcctctggtacacacccatccggcgggagtggtactac
gaggtcatcattgtgcgggtggagatcaacgggcaggacctgaaaatggactgcaaggag
tacaactacgacaagagcatcgtggatagtggcaccaccaaccttcgtttgcccaagaaa
gtgtttgaagctgccgtcaaatccatcaaggcagcctcctcgacggagaagttcccggat
gggttctggctgggggagcagctggtgtgctggcaggcaggcaccaccccttggaacatt
ttcccggtcatctccctctacctaatgggcgaggtcaccaatcagtccttccgcatcacc
atccttccacagcaatacctacggccagtggaagacgtggccacgtcccaagatgactgc
tacaagttcgccatctcacagtcctccacgggcactgtgatgggagctgtgatcatggag
ggcttctacgtcgtctttgatcgggcccgaaagcgaatcggctttgctgtcagtgcttgt
cacgtgcacgatgagttcaggacggcggcggtggaaggcccatttatcaccccggacatg
gaagactgtggctacaacatcccacagacagacgagtcgaccctcatgaccatagcctac
gtcatggcggccatctgcgccctcttcatgctgccgctctgcctcatggtgtgccagtgg
cgctgcctccgctgcctgcgccatcaacacgatgactttgctgatgacatctccctgctg
aagtga
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