Lactococcus cremoris subsp. cremoris KW2: kw2_0345
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Entry
kw2_0345 CDS
T02848
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase MurF
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
llw
Lactococcus cremoris subsp. cremoris KW2
Pathway
llw00300
Lysine biosynthesis
llw00550
Peptidoglycan biosynthesis
llw01100
Metabolic pathways
llw01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
llw00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
kw2_0345 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
kw2_0345 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
kw2_0345 (murF)
Enzymes [BR:
llw01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
kw2_0345 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AGV72328
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Position
337448..338770
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AA seq
440 aa
AA seq
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MKLTIHEIAQVVGAKNDWSQLADLSVNKIEFDSRLIEKGDIFLPLKGARDGHDFIEIAFD
NGAIISFSEKEVEQAHLLVDDNLAAFQTLAKYYLEKTKVPVIAVTGSNGKTTTKDMIAAV
LSKKYKTYKTQGNHNNEIGLPYTILHMPEDTEKLVLEMGMDHPGDIDFLSQLAQPELALI
TLIGEAHLEFMGSRENIAKGKMGITAGLHGELIAPADPIINAFIPENQKISRFGLPGEDL
FITKLIEHKERLTFETNFLDESITIPVPGKYNATNAMLAAYVGLHYGLTEAEIKKALKEV
ELTRNRTEWKKSKNGADLLSDVYNANPTAMRLILETFQAIPKNENGRKIAVLADMLELGP
TAAQLHKEVLKSIDFTKIDKVYLYGEMMKNLADISTDKPVSYFTDLDLLTESLSADLKPA
DQVLFKGSNSMKLSEVVEKL
NT seq
1323 nt
NT seq
+upstream
nt +downstream
nt
atgaaactcacaattcacgaaatcgctcaagtcgttggcgcaaaaaatgattggtcgcaa
ctggcagatttgtcagtaaataaaattgaatttgacagccgtttaattgaaaaaggagat
atctttttgccactcaaaggggcacgagatggtcatgatttcatcgagattgcttttgac
aatggagcaataattagcttttcagaaaaagaagttgaacaagctcatcttttggttgat
gataatctagcagctttccaaacattagcaaaatattatctggaaaaaacaaaagttcca
gttattgcggtgacaggctcaaatggtaaaacaaccaccaaggatatgattgctgctgtt
ttatctaaaaaatataaaacctataaaacacaaggaaatcataataacgaaattggattg
ccttacacaattttacacatgccagaggatactgaaaaattagtattagaaatgggaatg
gaccaccctggcgatattgattttctctcacaactagctcaacctgaactagctcttatt
accttaattggtgaagctcatcttgaatttatgggtagtcgtgaaaatattgcaaaaggt
aaaatgggtattactgctggtctacatggtgaattaattgcccctgctgacccaattatt
aatgcttttattccagaaaatcaaaaaatcagtcgttttggtttgcccggtgaagattta
ttcattacaaaattaattgagcacaaagaaagattgacttttgaaactaattttttagat
gaatcaataacgattccagttcctggtaaatataatgcaacgaatgctatgttagctgct
tatgttggcttacattatggattgacagaagctgaaatcaaaaaagctttgaaagaagtt
gaactgaccagaaatcggacagagtggaaaaaatctaaaaatggagctgaccttttaagc
gacgtctataatgccaatccaacagctatgcgcctgattttggaaactttccaagccatt
cctaaaaatgaaaatggtcgaaaaatcgcagttcttgctgacatgttagaactcggacca
acagctgctcaacttcataaagaggtgctgaaatcgattgatttcacaaaaattgataaa
gtctatctttatggcgaaatgatgaaaaatttggcagatatttcgactgacaaacctgtc
agctattttacagatttggatttactgacagaaagtctgtcagcagatttgaaaccagca
gaccaagttttattcaagggctcaaacagcatgaaactttcagaagttgttgaaaaatta
taa
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