Lactococcus cremoris subsp. cremoris KW2: kw2_1179
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Entry
kw2_1179 CDS
T02848
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase LeuA
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
llw
Lactococcus cremoris subsp. cremoris KW2
Pathway
llw00290
Valine, leucine and isoleucine biosynthesis
llw00620
Pyruvate metabolism
llw01100
Metabolic pathways
llw01110
Biosynthesis of secondary metabolites
llw01210
2-Oxocarboxylic acid metabolism
llw01230
Biosynthesis of amino acids
Module
llw_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
llw00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
kw2_1179 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
kw2_1179 (leuA)
Enzymes [BR:
llw01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
kw2_1179 (leuA)
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Motif
Pfam:
HMGL-like
HCS_D2
LeuA_dimer
DUF364
ANAPC4
Motif
Other DBs
NCBI-ProteinID:
AGV73137
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Position
1227319..1228860
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AA seq
513 aa
AA seq
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MRKIEFFDTSLRDGEQTPGVSFSIAEKVTIAKQLEKWGISVIEAGFPAASPDSFEAAKQI
SKALKETAVTALARCVITDIDKAVEAVREAQHPQIHVFIATSPIHMKYKLKISPDEVLKT
IDKCVRYAHEQVEVVEFSPEDATRTEPEFLLKAVQTAVDAGATYINIPDTVGYTTPEEYG
KIFKMLIDNIKADREIIFSPHCHDDLGMAVANSLAAIKAGAGRVEGTVNGIGERAGNAAL
EEIAVALHIRKDYYQAKSPLVLAETMATAELISQFSGIAIPKNKAVVGANAFAHESGIHQ
DGVLKNAETYEIISPELVGIKHNSLPLGKLSGRHAFTEKLTELNISYDAKELPNLFERFK
RLADKKKEITDADIHALFTGETVKNLAGFILNNVQIDGHKALVELKNQDAEIYVSQGEGS
GSVDAIFQAIDKVFNHQLKLISYSVDAVTDGIDAQATTVVSVENLATGTIFNAKGVDYDV
LKGSAIAYMNANVLVQKENSQGKVEQISAHDGI
NT seq
1542 nt
NT seq
+upstream
nt +downstream
nt
atgcgaaaaattgaattctttgacactagcctaagagatggcgaacaaacacctggcgtg
agtttttccatagccgagaaggtaactattgcaaaacaacttgagaaatgggggatatct
gtgattgaagctggctttcctgcagcgagtccggatagttttgaagctgcaaaacaaatt
tctaaagctttaaaggagacggcggtaacagcattagctcgttgcgttataactgacatt
gataaagcagtagaggcagtaagagaagctcaacatccgcaaattcatgtttttattgcc
acttcacccattcacatgaaatataagctcaaaataagtcctgatgaagttctaaaaacg
attgataaatgcgtaagatatgctcatgagcaggttgaagttgttgaattttcgccggaa
gatgcgacacgtactgaaccagaatttctcttgaaagccgttcaaacagcagtagatgct
ggagcaacttacatcaatattcctgatactgttggttatacaactccggaagaatatgga
aaaatatttaaaatgttgattgataatattaaagctgaccgtgaaattatttttagtccg
cattgtcatgatgatttagggatggctgtagcaaattcattagcagcaattaaagctgga
gcgggtagagtagaaggtacggtcaatggaattggcgaacgggctggaaatgctgcgctt
gaagaaattgcagttgctttgcatattcgtaaggattattatcaggcgaaaagtccctta
gtccttgcggaaacaatggcaacagcagaattaatttcgcaattttcaggaattgctatt
cctaaaaacaaggcggttgttggggcaaatgcattcgctcatgaatctggaattcatcag
gatggtgttcttaaaaatgccgaaacttatgaaatcattagtccagaacttgttggaata
aaacacaattcactaccactcgggaaactgtcaggtcggcatgcatttactgaaaaactg
accgaacttaatatttcatatgacgcaaaggaacttccaaacctgtttgaacgttttaaa
cgtctggctgacaagaaaaaggaaattactgacgctgatattcatgctttattcacgggc
gaaacggtgaaaaatctggctggtttcattcttaataatgttcagattgatgggcataaa
gcactagtcgaactcaaaaaccaagatgctgaaatttatgtcagtcagggagagggttct
ggttcagttgatgcaattttccaagccattgataaagtctttaatcatcaactaaaatta
atttcttattctgttgatgctgtgactgatgggattgatgcacaagcaacaaccgttgtt
tctgtcgaaaatctcgctaccggtacaatttttaatgctaaaggggtcgattatgatgtc
ttaaaaggtagtgcgattgcttatatgaatgcgaatgtactggtacagaaagaaaactca
caaggaaaggttgaacaaatttcagctcatgatggaatttaa
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