Lactococcus lactis subsp. lactis NCDO 2118: NCDO2118_0405
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Entry
NCDO2118_0405 CDS
T03437
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
llx
Lactococcus lactis subsp. lactis NCDO 2118
Pathway
llx00300
Lysine biosynthesis
llx00550
Peptidoglycan biosynthesis
llx01100
Metabolic pathways
llx01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
llx00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
NCDO2118_0405 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
NCDO2118_0405 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
NCDO2118_0405 (murF)
Enzymes [BR:
llx01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
NCDO2118_0405 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF6585
Motif
Other DBs
NCBI-ProteinID:
AII11904
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Position
388792..390114
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AA seq
440 aa
AA seq
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MKLTIHEIAQVVGAKNDWSQLADLSVNKIEFDSRLIEKGDIFLPLKGARDGHDFIEIAFD
NGAIISFSEKEVEQAHLLVDDNLLAFQKLAKYYLEKTKVPVIAVTGSNGKTTTKDMIAAV
LSKKFKTYKTQGNHNNEIGLPYTILHMPDDTEKLVLEMGMDHPGDIDFLSELAKPELAVI
TLIGEAHLEHMGSRENIAKGKMGITAGLHGELIAPADPIINAFIPDNQKIIRFGLPGEDL
FITKLVEHKEKLTFETNFLDESITIPVPGKYNATNAMLAAFVGLHYGLSEAEIKKALKEV
ELTRNRTEWKKAKNGADLLSDVYNANPTAMRLILETFQAIPKNENGRKIAVLADMLELGP
SAAQLHKEILKSIDFNKIDKVYLYGEMMKNLAEISTDKAVSYFTDLDLLTESLSADLKPT
DQVLFKGSNSMKLSEVVEKL
NT seq
1323 nt
NT seq
+upstream
nt +downstream
nt
atgaaactcacaattcacgaaatcgcccaagtcgttggcgcaaaaaatgattggtcgcaa
ctggcagatttgtcagtcaataaaattgaatttgacagccgtttgattgaaaaaggggat
atctttttgccacttaagggggcacgagatggtcatgatttcatcgaaatcgcttttgat
aatggagcaataatcagcttttcagaaaaagaagtcgaacaagctcatctcttggttgac
gataatctgcttgctttccaaaaattagcaaaatattatcttgaaaagacaaaagttcca
gtcattgcggtgacaggttcaaatggaaaaacaacaaccaaagacatgattgctgctgtt
ttgtctaagaaatttaaaacatacaaaacacaaggaaatcacaataatgaaatcggctta
ccctacaccattttacatatgccggacgatactgaaaaattagttttggaaatgggaatg
gatcaccctggtgatattgattttttatcagaacttgctaagcctgaacttgctgttatt
accttaattggtgaagcacatcttgaacatatgggaagtcgcgaaaatattgctaaaggg
aaaatggggattacggctggtttgcatggtgagcttattgcccctgctgacccaattatt
aatgcttttatcccagacaatcaaaaaattattcgctttggtttgcccggtgaagattta
tttattacaaaattagtcgaacacaaagaaaaattaacttttgaaactaattttttagat
gaatcaattactattccagttcctggtaaatataacgcgacgaatgctatgttagctgct
tttgttggcttacattatggactttcagaagccgaaattaaaaaagctttgaaagaagta
gagctgaccagaaatcggacagagtggaaaaaagcaaaaaatggtgcagaccttttgagt
gatgtttataatgccaatccgacagcaatgcgtttgattttggaaactttccaagccatt
cctaaaaatgagaatggtcgaaagattgcagttcttgctgatatgttagaacttggaccc
agtgcagcccaactccataaagaaatattgaaatctattgatttcaataaaattgataaa
gtctatctttatggtgaaatgatgaaaaacttggcagaaatttcgactgacaaagcggtc
agctattttacagatttagatttactgacagaaagtctgtcagcagatttgaaaccaact
gaccaagtgttattcaaaggttcaaatagcatgaaactttcagaggttgttgaaaaatta
taa
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