Leishmania major: LMJF_35_0050
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Entry
LMJF_35_0050 CDS
T01014
Name
(RefSeq) putative 2-oxoisovalerate dehydrogenase beta subunit, mitochondrial precursor
KO
K00167
2-oxoisovalerate dehydrogenase E1 component subunit beta [EC:
1.2.4.4
]
Organism
lma
Leishmania major
Pathway
lma00280
Valine, leucine and isoleucine degradation
lma00640
Propanoate metabolism
lma00785
Lipoic acid metabolism
lma01100
Metabolic pathways
lma01110
Biosynthesis of secondary metabolites
lma01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
lma00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
LMJF_35_0050
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
LMJF_35_0050
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
LMJF_35_0050
Enzymes [BR:
lma01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
LMJF_35_0050
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Motif
Pfam:
Transketolase_C
Transket_pyr
PFOR_II
Transketolase_C_1
Motif
Other DBs
NCBI-GeneID:
12982189
NCBI-ProteinID:
XP_003722402
UniProt:
E9AEI2
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Position
35:complement(17610..18710)
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AA seq
366 aa
AA seq
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MRRLFDASATAVVAASSAAAKRHGSVQPSEFVFAPAPGEEEAMRNGVKMNLFQAVNSGLD
HALSKERTVLLGEDVAFGGVFRCTLDLRKKHGPQKVFDSPLTEQGIVGFAVGMAAVGWHP
IAEVQFADYIFPAFDQIVNEAAKYRFRTGSNFHCGMLIRAPCSAVGHGGIYHSQSVEGYF
THCPGLKIVMPSSPSEAKGLLLKCVEENDPCIFFEPKILYRSAVEEVNPDYYTLPLGKGR
ILVEGRDVTMVTYGSQVYVAAKAAEMARKEGISVELIDLRSLLPWDRQLVADSVKKTGKV
IVTHEAPKTSGYGAELVSSITEDCFLSLEAPPTRVCGLDTPFPLHERLYLPNELKLLDAI
KSVVHF
NT seq
1101 nt
NT seq
+upstream
nt +downstream
nt
atgcgtcgcctctttgatgcctctgccactgcggtcgttgcagccagctctgcggcggcc
aagaggcatggtagcgttcaaccgagtgagtttgtattcgcgcccgcgcccggcgaggaa
gaggcgatgcgcaacggcgtcaagatgaacttgtttcaggcggtcaactcgggtcttgat
cacgcactatccaaagagaggacggtacttctcggtgaagacgtcgcgttcggcggcgtt
tttcgttgcacgcttgatctgcgcaagaagcatggtccgcagaaggtattcgactcgccg
ctaacggaacagggcattgtcggttttgcggtgggcatggctgccgtcggctggcatccc
atcgccgaggtacagttcgccgactacatctttccagcctttgaccagattgtgaacgaa
gctgccaagtaccgctttcgcacgggcagcaactttcactgtggcatgctgattcgcgcc
ccgtgctctgcagtgggccacggtggcatttaccactcacagagtgttgagggatacttt
actcactgccctggattgaagattgtcatgccgtcgtctccgtcggaggcaaagggcctg
ttgctgaaatgtgtcgaggagaacgacccctgcatcttcttcgagcccaagattctctac
cgcagtgcagtggaggaggtgaacccggactactacacactgccgctgggcaagggccga
attctcgtagagggacgtgacgtgactatggttacctacggttctcaagtgtacgtggca
gccaaggcggcagagatggcgcgcaaggagggcatttccgtagagctcattgaccttcgc
agcttgttgccgtgggaccgtcaactggtggcggactcagtgaagaagacgggtaaagtc
attgtcacgcatgaggcgccaaagacgagcgggtacggtgccgagctggtgtctagcata
acagaggactgcttcctctcgctcgaggccccgccgacgcgcgtgtgcggcttggacacg
ccgttccctttgcacgagcgcctctacctaccaaacgagctgaagctgttggacgctatc
aagtccgtggtgcacttctga
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