Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293: LEUM_0264
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Entry
LEUM_0264 CDS
T00411
Name
(GenBank) D-alanine--D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
lme
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293
Pathway
lme00470
D-Amino acid metabolism
lme00550
Peptidoglycan biosynthesis
lme01100
Metabolic pathways
lme01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
lme00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
LEUM_0264
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
LEUM_0264
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
LEUM_0264
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
lme01011
]
LEUM_0264
Enzymes [BR:
lme01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
LEUM_0264
Peptidoglycan biosynthesis and degradation proteins [BR:
lme01011
]
Precursor biosynthesis
Amino acid ligase
LEUM_0264
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Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
CPSase_L_D2
ATP-grasp
Motif
Other DBs
NCBI-ProteinID:
ABJ61391
UniProt:
Q03ZI1
Structure
PDB
PDBj
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All DBs
Position
223938..225071
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AA seq
377 aa
AA seq
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MTKKRVALIFGGNSSEHDVSKRSAQNFYNAIEATGKYEIIVFAIAQNGFFLDTESSKKIL
ALEDEQPIVDAFMKTVDASDPLARIHALKSAGDFDIFFPVVHGNLGEDGTLQGLFKLLDK
PYVGAPLRGHAVSFDKALTKELLTVNGIRNTKYIVVDPESANNWSWDKIVAELGNIVFVK
AANQGSSVGISRVTNAEEYTEALSDSFQYDYKVLIEEAVNGARELEVGVIGNDQPLVSEI
GAHTVPNQGSGDGWYDYNNKFVDNSAVHFEIPAQLSPEVTKEVKQMALDAYKVLNLRGEA
RMDFLLDENNVPYLGEPNTLPGFTNMSLFKRLWDYSDINNAKLVDMLIDYGFEDFAQNKK
LSYSFVSLGEEKIGKFN
NT seq
1134 nt
NT seq
+upstream
nt +downstream
nt
atgactaaaaaaagagtagcgcttatttttggaggtaattcctctgagcacgacgtatca
aagcgttcagcgcaaaatttctataatgcaatcgaagcaactggtaaatatgaaattatt
gtttttgcaattgcccaaaatggtttctttttagatacggaaagttctaagaaaatactt
gcgttagaagatgaacagcccattgtggacgccttcatgaaaactgtcgatgctagtgat
ccattggcgcgcattcatgctttaaagagtgcgggtgactttgatattttcttccctgta
gttcatggtaacttaggagaagatggtacactgcaaggtttatttaaactattagataaa
ccatatgtgggggcaccgttacgtggccatgcggtaagctttgacaaagctttgactaaa
gaactattgacggtaaatggtattcgcaatactaaatacattgtggtggaccctgagtca
gcaaacaattggtcgtgggataagattgtggctgaattaggcaacattgtgtttgttaaa
gctgctaatcaaggatcttcagtgggaatttcacgtgtaaccaatgccgaagaatatact
gaagcattatcagattcattccaatatgattataaagttttgatagaagaagcagtcaat
ggtgcccgagagttggaagttggtgtgattggtaacgatcagccgcttgtctctgagatt
ggcgcacatacagtgccaaatcagggtagtggggacggttggtatgattataataataag
ttcgttgataattccgctgttcactttgaaattcctgctcagttatccccagaagtaaca
aaagaagttaaacaaatggctttagatgcttataaagtattgaatttacgtggcgaagcg
cgaatggattttttgttagatgaaaataatgttccctacttaggtgaaccaaacacgtta
ccagggttcacgaatatgtcgttatttaaacgtttgtgggattattctgatattaacaac
gccaagctagttgatatgttgattgactacgggtttgaagattttgcacaaaataaaaaa
ttgagttactcatttgtgtcacttggagaagaaaagatagggaagtttaactaa
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