Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293: LEUM_0452
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Entry
LEUM_0452 CDS
T00411
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
lme
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293
Pathway
lme00300
Lysine biosynthesis
lme00550
Peptidoglycan biosynthesis
lme01100
Metabolic pathways
lme01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
lme00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
LEUM_0452
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
LEUM_0452
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
LEUM_0452
Enzymes [BR:
lme01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
LEUM_0452
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
LpxD
Motif
Other DBs
NCBI-ProteinID:
ABJ61568
UniProt:
Q03Z04
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Position
413431..414759
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AA seq
442 aa
AA seq
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MNYSVKKIGQILNATTQIDSKIVTGVSFDSRKVKSGDLFVALVAENDGHDYVQQALTKGA
TAVLVDDRHQIDSKIPAIIVSDTLLALQQLGEYRRHQINPKVVAITGSNGKTTTKDMASA
IMGSQYKTFKTPENFNNEIGVPLTLLTMPDDTEVLVVELGMDRPGQLTTLSELVSPDIAI
ITMIGEAHIEFFKTRENIAKAKLEITKGLKSQGTLLVPYDEPLLTNAQVKQNVQTFGQDI
KDINSSSSKTIFTYQNTRFAIPLLGRYNIMNALAAISAGILLHIELKNAAEALQHFDLTK
NRTEQLTTSHGVNLISDVYNSNPTAVAAVLATLKIIPATHKYVVLGDMLELGEQAASLHA
CLAETVINANVDGVYLVGPLMNKYLYPILQRRFDSAHLHQYETDQLAELIKDLQTLGENG
DVILLKASHGIHLENVVNALVK
NT seq
1329 nt
NT seq
+upstream
nt +downstream
nt
atgaattactcagtaaaaaagataggtcagatattaaatgcgacaacacaaatagattcc
aaaatagttactggtgtgtcttttgattctcgtaaagttaaatctggagatttatttgtt
gctctggttgctgaaaacgatgggcatgattatgtgcaacaggcgttgacaaaaggggcc
acagccgttttagtggacgacaggcatcaaatagattcaaaaattccagctattattgta
tcagacacattgttagctcttcagcaattgggagaatatcgtcgtcaccaaattaatcct
aaagttgttgctattactggttcaaatggtaaaacaacaacaaaagatatggcttcggca
ataatgggttctcaatacaaaacctttaaaacacctgaaaactttaacaatgaaattggt
gttcctttgacgttgctcaccatgccagatgatacagaagtgttagtggtagaattaggt
atggatcgacctggtcaattgacgacattatctgagttagtgagtccagacattgccatc
attactatgattggagaggcgcatattgagtttttcaaaacacgtgaaaatatcgctaag
gcaaaactcgaaattactaaaggtctcaaatcacaaggaacattattggttccttacgat
gaacctcttctgacaaatgcacaagttaaacaaaatgtgcaaacctttggacaagatatt
aaagatattaattcgtcatcctccaagacaatttttacttatcaaaatactcgatttgct
attccactgttgggtcggtataatataatgaatgcgctcgcagcgatttcagcgggtatc
ttattacatattgaattaaaaaacgctgcagaagcgcttcagcattttgatttgacaaaa
aatcgcacagaacagctcaccacatctcacggcgtgaacttaattagcgatgtttataac
tcaaatccaacggctgttgctgctgtcttagcaacattaaaaattataccggccacacac
aagtatgttgtgttgggtgatatgttagaattaggcgaacaggctgcaagcttgcacgct
tgtctggcagaaacggtgataaatgcgaatgttgatggcgtttacttggttggaccattg
atgaataaatatctatatccaatcttgcaacgacgctttgattcagcgcacttgcaccaa
tatgaaacagatcagttagccgaattaatcaaagatttacagacgttaggtgaaaacggg
gacgtgattttgttaaaagcaagtcatgggattcatcttgagaacgttgttaacgcattg
gtaaaatag
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