Leishmania mexicana: LMXM_21_1430
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Entry
LMXM_21_1430 CDS
T02288
Name
(RefSeq) 2-oxoisovalerate dehydrogenase alpha subunit,putative
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
lmi
Leishmania mexicana
Pathway
lmi00280
Valine, leucine and isoleucine degradation
lmi00640
Propanoate metabolism
lmi00785
Lipoic acid metabolism
lmi01100
Metabolic pathways
lmi01110
Biosynthesis of secondary metabolites
lmi01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
lmi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
LMXM_21_1430
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
LMXM_21_1430
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
LMXM_21_1430
Enzymes [BR:
lmi01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
LMXM_21_1430
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Motif
Pfam:
E1_dh
DUF4440
Motif
Other DBs
NCBI-GeneID:
13454031
NCBI-ProteinID:
XP_003875399
UniProt:
E9AVC7
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All DBs
Position
21:complement(560513..561952)
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AA seq
479 aa
AA seq
DB search
MFHISRAVRCNALATAIAGRTALSDAIRQVQKVWNLDFKDGPATTSTLAFNDEPDPAAPI
FHVLDLQGRVVVEDTADSGAPAATPSTVDEAGKIELQSAELGEAFRYHAKDETSVITREV
AERMMSAMLAHNTMDKIMLEAQRQGRISFYMTMFGEEAAVIGAAAGLASNDELFAQYREA
GILTYRGYTIPEFIAQCMGNCECDLKGRQMPIHYGSNRLHAQMVSSPLATQIPHGAGAGY
AFRLENQALERRLPAGTLLSTIPEARICATFFGEGAASEGDFHAGLNFASTVGSHTLFFV
RNNGYAISTPTHSQYMGDGILSRAAGYGMPAARVDGLDALAVYHTVRKAREMILNNHRPV
LVEALTYRLSHHSTSDDSTAYRSRDEIEHFAETFSPIERFERFMAERGWWTPVQSKEVVE
KTRKEVLSELRRQEKLPAWPVSTLCDDVFEHMTPELERQRAQLVEHYEAHRSIYDQEKL
NT seq
1440 nt
NT seq
+upstream
nt +downstream
nt
atgtttcacatctctcgtgcagtgcgctgcaacgcactcgccaccgccatcgctggccgt
accgcgctaagtgacgcgatacgccaggtgcagaaggtgtggaatcttgacttcaaggat
ggaccggctaccacgagcacgctggcgttcaatgacgagcctgacccggccgcaccgatc
ttccatgtgctcgatttgcaaggccgtgtcgttgtggaggacacggcggacagcggagcc
cctgcagcaacgccttcaaccgtcgatgaggctggcaaaatcgaactgcagagcgccgag
cttggggaggcatttcgctaccatgcaaaggatgagacgagcgtcatcactcgcgaggtg
gcggagcgcatgatgtcggcgatgctggcgcacaacaccatggataagataatgctagag
gcgcagcggcaaggtcgcatctccttctacatgacgatgttcggcgaggaggccgccgtg
atcggcgcggcggctgggctggccagcaacgacgagctcttcgcgcagtacagagaggct
ggtatcctgacgtaccgcggctacactatacccgagtttatcgcgcagtgcatgggcaac
tgcgagtgcgatttgaagggccgtcagatgcccatccactacggcagcaaccgtctgcat
gctcagatggttagctccccactcgccacgcagatcccgcacggcgccggcgccggctac
gcgttccggttagagaaccaggcgctggagaggaggctgccggctggcacgctgctgtcg
acgattccggaagcgcgcatctgtgccaccttcttcggcgagggagccgcgagcgagggc
gacttccacgcggggctgaacttcgctagcaccgtcggctcgcacaccctcttctttgtg
cgcaacaatggctacgccatctccaccccgacccacagccagtacatgggcgacggcatc
ttgagccgtgcggcaggctacggcatgccagccgcccgcgtcgacggcctcgatgcgctg
gcggtttaccatacggtgcgcaaggcacgtgaaatgatcctgaacaaccaccggcccgtc
ctggtggaggcactgacgtatcgcctctcacaccactcgacctcggacgacagtaccgcg
taccgctcgcgggacgagattgagcactttgcagagacctttagccccatcgagcgcttc
gagcgcttcatggcagagcgcggttggtggacgcccgtgcagtcgaaggaggttgtcgag
aagacccggaaagaggtgcttagcgagctgcgtcggcaggagaagctgcctgcatggccg
gtatcgaccctctgcgatgacgtctttgagcatatgacgccagagctggagcgacagagg
gcgcagctggtggagcactacgaggcacaccggtccatctacgatcaggagaagctttag
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