KEGG   Labrus mixtus (cuckoo wrasse): 132972542
Entry
132972542         CDS       T10666                                 
Symbol
map2k1
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 1 isoform X1
  KO
K04368  mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
Organism
lmix  Labrus mixtus (cuckoo wrasse)
Pathway
lmix04010  MAPK signaling pathway
lmix04012  ErbB signaling pathway
lmix04068  FoxO signaling pathway
lmix04114  Oocyte meiosis
lmix04140  Autophagy - animal
lmix04148  Efferocytosis
lmix04150  mTOR signaling pathway
lmix04210  Apoptosis
lmix04218  Cellular senescence
lmix04270  Vascular smooth muscle contraction
lmix04370  VEGF signaling pathway
lmix04371  Apelin signaling pathway
lmix04510  Focal adhesion
lmix04517  IgSF CAM signaling
lmix04519  Cadherin signaling
lmix04540  Gap junction
lmix04620  Toll-like receptor signaling pathway
lmix04810  Regulation of actin cytoskeleton
lmix04910  Insulin signaling pathway
lmix04912  GnRH signaling pathway
lmix04914  Progesterone-mediated oocyte maturation
lmix04916  Melanogenesis
lmix05132  Salmonella infection
Brite
KEGG Orthology (KO) [BR:lmix00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    132972542 (map2k1)
   04012 ErbB signaling pathway
    132972542 (map2k1)
   04370 VEGF signaling pathway
    132972542 (map2k1)
   04371 Apelin signaling pathway
    132972542 (map2k1)
   04068 FoxO signaling pathway
    132972542 (map2k1)
   04150 mTOR signaling pathway
    132972542 (map2k1)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    132972542 (map2k1)
   04519 Cadherin signaling
    132972542 (map2k1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    132972542 (map2k1)
   04148 Efferocytosis
    132972542 (map2k1)
  09143 Cell growth and death
   04114 Oocyte meiosis
    132972542 (map2k1)
   04210 Apoptosis
    132972542 (map2k1)
   04218 Cellular senescence
    132972542 (map2k1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    132972542 (map2k1)
   04540 Gap junction
    132972542 (map2k1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    132972542 (map2k1)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    132972542 (map2k1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    132972542 (map2k1)
   04912 GnRH signaling pathway
    132972542 (map2k1)
   04914 Progesterone-mediated oocyte maturation
    132972542 (map2k1)
   04916 Melanogenesis
    132972542 (map2k1)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    132972542 (map2k1)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    132972542 (map2k1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:lmix01001]
    132972542 (map2k1)
Enzymes [BR:lmix01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     132972542 (map2k1)
Protein kinases [BR:lmix01001]
 Serine/threonine kinases: STE group
  STE7 family
   132972542 (map2k1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Pkinase_fungal Kinase-like Haspin_kinase Seadorna_VP7
Other DBs
NCBI-GeneID: 132972542
NCBI-ProteinID: XP_060891434
LinkDB
Position
4:6839983..6851155
AA seq 395 aa
MQKRRKPEPIQLNPIPDGNTINGTGATETNLEALQKKLEELELDEQQRKRLEAFLTQKQK
VGELKDDDFEKICELGAGNGGVVFKVSHRPSGLIMARKLIHLEIKPAIRNQIIRELQVLH
ECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQSLKKAGKIPEQILGKVSIAVIKGLSY
LREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTH
YSVQSDIWSMGLSLVEMAIGRFPIPPPDAHELEQIFGFPMEGEAASSESSPKPRPPGRPG
SSYGPDSRPPMAIFELLDYIVNEPPPKLPGLFSPEFQDFVNKCLIKNPAERADLKQLMVH
AFIKQSEAEQVDFAGWLCSTIGLNQPVTPTHGTAM
NT seq 1188 nt   +upstreamnt  +downstreamnt
atgcagaagagaaggaagccagagccgattcaactcaacccgatccccgatggaaacact
atcaacggtaccggagccacggaaacaaacttggaggcgctgcagaagaagctcgaggag
ctcgagttggacgagcagcagaggaaacgcctggaggcctttctaacacagaagcagaag
gtgggagagctgaaagacgatgactttgagaagatctgtgagctcggggcgggcaacgga
ggagttgtcttcaaggtctcccacagaccctctggcttgattatggcgaggaagctgatc
cacctggagatcaaacctgccatcaggaaccagatcattagggagctgcaggtgctgcat
gagtgtaactccccttacattgtgggcttctacggggcgttttacagtgatggagaaatc
agcatctgtatggagcatatggacggcggctccctggaccagtctctgaagaaggcgggc
aagatcccagagcagatccttggcaaagtcagcatcgctgtcatcaaagggctgtcgtac
ctaagggaaaaacacaagatcatgcacagagatgtcaagccctccaacatcctggtgaat
tcccgcggtgagatcaagctgtgtgactttggagtgagcggacagctcatcgactccatg
gctaactcctttgtgggcactcgctcttacatgtctccagagcgtttgcagggcacacat
tactctgttcagtcagacatctggagtatgggtctgtccctggttgaaatggccattgga
cgcttccccatcccaccacctgatgctcacgaactggaacaaatatttggcttcccaatg
gaaggggaggccgcctccagtgagtcctccccgaagccccgcccccccgggcgaccaggc
agctcatacggacctgacagcagaccaccgatggcaatattcgagctgcttgattatatt
gtcaatgagcctccaccgaagctaccaggactttttagccctgaatttcaagactttgtg
aataaatgcctgatcaagaatcctgcagagagagcagacctcaaacagttgatggtgcat
gctttcatcaaacagtctgaggcagagcaggttgactttgctggctggttgtgcagtacc
attggactcaatcagcctgtgacacccacacacggtactgcgatgtga

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