Labrus mixtus (cuckoo wrasse): 132975467 Help Entry 132975467         CDS       T10666                                  Symbol ryr2b Name (RefSeq) ryanodine receptor 2   KO K04962   ryanodine receptor 2 Organism lmix  Labrus mixtus (cuckoo wrasse) Pathway lmix04020   Calcium signaling pathway lmix04260   Cardiac muscle contraction lmix04261   Adrenergic signaling in cardiomyocytes lmix04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:lmix00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     132975467 (ryr2b)    04020 Calcium signaling pathway     132975467 (ryr2b)  09150 Organismal Systems   09153 Circulatory system    04260 Cardiac muscle contraction     132975467 (ryr2b)    04261 Adrenergic signaling in cardiomyocytes     132975467 (ryr2b)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:lmix04040]     132975467 (ryr2b)    04990 Domain-containing proteins not elsewhere classified [BR:lmix04990]     132975467 (ryr2b) Ion channels [BR:lmix04040]  Voltage-gated cation channels   Ryanodine receptor    132975467 (ryr2b) Domain-containing proteins not elsewhere classified [BR:lmix04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    132975467 (ryr2b) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 SPRY MIR Ins145_P3_rec RIH_assoc Ion_trans EF-hand_1 EF-hand_6 EF-hand_7 EF-hand_8 HbrB Motif Other DBs NCBI-GeneID:  132975467 NCBI-ProteinID:  XP_060896000 LinkDB All DBs Position 6:complement(12229078..12295596) Genome browser AA seq 4962 aa AA seqDB search MTDTGEGDEEYQFLRTGDDVVLQSTFTSQDEHVKLCLAAEGFGSRLCRLEPTSNCKNVPP ELSVCGFVLAQCLSVRALQEMLAHSQHLSTEIDITKQSSQVGAGGSQRTLLYGQAVLFLH SYSGMYLSCLSSSQSSADKLAFDVGLQEDKAGETCWWTVHPASRQRSEGEKVRVGDDLIL VNVSSERYLHLSFGTVFDNKSLSDSLIVNAAFQQTLWSVAPICSGGGVAQGYLKGGDTLR LLHSHSDACLTVPSIEKGEELQRIMHYESGSVCSHARSLWRLEILRVGWCGRHTCWGQPF RLCHMTTGRYLGLTEERGLHLVDRDRADVNTTSFCFRSSKEKLDTGKKTNMEGMGTPEIK YGDSICFVQHVNSGLWLTYQAIDAKTTRMVVAQRKAILHSEGHMDDGLTLSRSQKEESHT ARLIRSATLLFSCFIRKLDVSSQNEHVMSASLPMEKVTQSLQDLIDYFQPPAEGLEHEAK QNNLAALKNRQNMFQEEGVLDLVLDCIDRLHQYSTASHFTEAAQIDTGGEWETILNRFYE LLAALIRGNPVNCAHFSASLDWLISKLERLEASSGVLEVLQCVLVESPEALNVIKEGHIH SIISFLDKHGCNHKVLEVLCSLCVCHGVAVRSNQNLICDNLLPDRDLLLQTRLTNQVTSM RPNIFLAMGEDSAQHRRWYFELVVDHVESFLTPEPTHLRVGWACTEGYQPRPTGGEAWGG NGVGDDLCSYGFDGLHLWSGCMGRRVSSPLPHLLKDDDVVSCCLDLSAPCISFRVNGQPV QGMFENFSGDGLLHPVVSFSAGVTVHFLFGGRHGEFRFLPPPGFAPCSESLLPRVKLKVE PCHTYIFDHDKGKKELIGSLVPATPATFTPMPMDISKVVLPVQLEGIRDKLAENIHELWA MDRIDIGWTYGPVRDETNRHDPSLVEFSKLSEQGRNQNLQMAQDTLRTLLAFGFHMGLTD SSAEERVKYTRVAAKYEQPSGYKPAPLDLRQVFLSPTHEELVNLLAENDHNVWARERIKQ GWTYAAQQDVKAKRSPYLVPYSLLDERRRRVSMESVRETVCTLLAYGYSLETLNHKTTLL SNPYHFSVEKGRVFRPDKSYAVTQGKWYFEFEIVTAGKMRVGWARPDYTPDKELGSDDQA FVFDGFEAQWYHQGVEPLGRPWQRGDVVGCLVDMAECTMMVTLNGEMLFNDRGSELAAKD FDVRDGLLPVVSVEVNQVGRLNLGRQVDSLQYFTVCGQQEGYDPFAANMSRDPALWMSWK QPQFTSILPDNHNLQVTRVSGSTDSLSSLRVSQRLFAHHGGGSEIGFYRLSMSIECAAIL KSPAGGVLPVASNSLSPGRKDQEEVDSDFEVLMKSAHNFAGSRDELNHKDHSHDKTSRLK QRFMLKKTKPGLVNSNSSARLLEDVVVDKDNHDHLIQSSRYYYSVRVLPGQEPFNVWVGW VTSNFHQHDVTFDADNVQTVTVTLGDDSGKVQESVKRCNSYMVCAGEATGLSQSRRSAGL EIGCLIDTSTGLLTFTSSGVEMATFYQVEAGSKLFPAVFVKPTTSNMFQFELGRVKNVMP LSAGLLRSQRRNATPQCPPRFQVQKLSPVLWTRIPDCTLRVMVDRPDECHGWRVQCSEPL QVMCLHIPDENRCVDILELSEREDLFTFHQHTLLLYCCLCALGNTRVCHALCSHVDQSQM LHVIQNPHLPGQLRSVFYQLLTQVHLSSHFTACLMMNQEYIVPMTDQTREITLFPSPANA GNAQPPDARQGIPSSCFSPSLKPQMHFSSPCFVRSDGLEGDCAVEVSCSDSPEIPLDIVK NLTVEMLTTGVCAVGQGVRDPVGGSIELLLVPLIRLFYTLLVMGVFGDEDLGKVLRLIEP RVFSIDAETPEEEEEEELSDDEKEWKGGQNKDGESLKQGLLHMKLPEAVKIELCYLLSYL CDCQVRHRIESVIAFSDNFVGQLQENQSFRYNQVMQALNMSAALTARKTKEFRSPPQEQI NMLLGFRHDEQQENCPCPVEIQQLLQDFHHLLNTHCGIETDNDAEDEEVAEMSVKDRLLS LVGSVLGLKKKPIEAEESRLQSAKSLKKLISETMVHWAKETEMEDPELVRAVFTLLHRQY QGLEGQMAGPLSRAYTISQISEEDTMALLSSLSQIRSLLSVRMGKEEERLMIRKLGDIMN NKVFYQHPNLMRALGMHETVMEVMVNVLGEGELKEITFPKMVASCCRFLCYFCRISRHNQ GALFDHLRYLLENSSVGLASPSMRGATPLDVAAASVMDNNELALALKELDLQKVVQYLAD CGLQSCQMLVAKGYPDIGWNPVEGERYVDFLRSAVFCNGESVEENAYVVLKLLIRRPECF GPALRGDGGNGLLAAMEEAIRISEDPSMDGPCTMYQSNRTLDVVQDNDDDLIHMGHAIMT FYSALIDLLGRCAPEMHLIQGGKGEAIRIRAILRSLIPIQDLEGVISISFEIPSVAKDGL VDEPDLSTVFCPDHKAAMVLFLDRVYGIENQNFLLHLLQVGFLPDLQTAVSLDAADLGST DMALALNRYLCTSVLPLLTKCSDLLCSVEDHASLVDALIQAIYNLSRALSLTKAQRDTIE DCLLAVCSKLQPSMMQPLLRRLVFDVPKLTDYSKMPLKLLTCHYEQRWKYYSLAGGQDDQ SSASEEELHLSRKLFWGVFKALAKKPYEPQLFPLCVQSLAAVAKAIPPDHMDSSCTPHSE RKASTDTEGHFELQPVDTSNVSVPERLEFVVNKYAEHTHEKWSLDKFANGWVHGEQLCEN TKVHPLLKPYRALAEKEKEAYRWAIKETIKSMLAFGWTIERTKEGEAFGTHTCSRRVSQS GQLSFEGASTFSPKSLDMSSITLSWDQCAMAEHLAENYHNAWAKKKKLELESKGGGHSMF VPYDTLSAKEKTKFRERAQDILKFLQLNGYTVWRDRRTGELEFQAVANCFSYTLLRRLLS YTEECQEHMLELEVMQARGQMSKGERAPQQQLLNFFSKVVLPLLEQYVKSHRLYFLSTSL CSSGNQSHASKREKEMIASLFCKLATLVRHRISLFGNEGSQVASCLHVLAQALDARTLMK SAPESIQASLHSFFEAAAADLEMIVENLSVTLVCLPQSRSQQAKGVAKVLSYSSSILVPT LTSLFRHLCIQNFGEDLLLGSIQVSCYRILNSLYSLGTSSSIYMEGQRPAAGACLAALTG TFPVCFLEPSYNHNNPYSIYNTMNASEREDLGLLDQVEDMCPLLPSLDQALGEVEELACA GAGARLAPYIHVTEVTLPMLCNYMSLWWHWGPEGQQESPICTSITSQHASDLLGHILRVI HNHVGASQCEWMKQLAVFSQPIICKANSELLKSHFLPLMEKLKKRAGCVLLEEEQMKAEV CDTSEAELQLQEKFTVLVRDLYAFYPLLIPFVDSNRASWLKESNPDAEQLFSMVAEVFTF WAKSHNFKWEEQNYVVQNEINNLAFLVNKDNMSKFDHDKRRMKRKGDCYSTHTSLIVASM KRLLPVGLRVCFHNDQILLVLAKKGFTQKKTEDEIREDVFNYLNHLQSETSNCFGQEAVN AVHPRLFGAIAETKETVDKILEIARVLYYLDQVEHPQKSKKPAWHRVLSKQRKRAVVACL RMAPLYNLPRHRAVNLFIQGYNKSWISAEDLSFEEKLVEDLAKGGVTELCGGDREEEKDV GDVAKPIDPLLQLITLFSRSALTERRKLGNDSLYKSYASIMAKSCQSEDADDEEQEAKSF EEKEMEKQKLLYQQARLHRRGASEMVLQTISASKGAMGAMIAPTLKLGISVLSGGNATVQ QKMLDYLRAKQDVGFFQSMAGLMLSCSVLDLNAFERQNKAEGLGMAMDESSGEKVMPDKD VTCDLFRFLQLLCEGHNSDFQNYLRTQTGNNTTVNIIISTVDYLLRVQESISDFYWHYSG KDVIDFHGQQNFSKAIEVAKQVFNTLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHM QMKLSKDSRQIELLKELMDLQKDMVVFLLSMLEGNVVNGMIGKQMVDMLVESSGNVEMIL KFFDMFLKLKDLTSSEAFREYDPDHKGCISRKDFQKAMENCKRFSQTETHFLLSCSEADD SDIVDYEAFVDRFHEPAKDIGFSIAVLLTNLSEHMPNDIRLRTFLELAECVLTYFQPYLG RIEILGSGKRIERVYFEISESSRTQWEKPQVKESKRQFIFDVVNEGGEKEKMEMFVNFCE DTIFEMQLAAQISGSDTGERCVEKEDGSEDEGHDNKGIFFLYQWMLLLTSLLSVKNLKFI MKMSLKDILMSALFLLRFIVMAQVRCVCAVVHSILYVLYIAFVSGGLIEAAKRMKISDLL GGILEPTLDEVMEVPSGVDRLRKYPGSFSSQRELREVGQEAAVTSPRDVDVLSDIFGLQV KKEGGQYRLITQDLTASLSDLFNTASRAISTTDFSEKQQQLKAHTATEEKPEDEEIHLTK GKESEKKTGKEEAEAELTSKKCSHKSEEKDSQRSALLEIISTHNKSLLNYFARNFYNMRL LALFVAFAINFILLFYKVASLPASQEEKEVIASDYTEELSSPAEDDNEGKVYFVLEESSG YMEPSLHFLAVAHTVISFCCMIGYYCLKVPLVIFKREKEVARRLEFDGLYVTEQPPEEDI KGQWDRLVINTPSFPSYYWDKFVKRKVMDKYGDFYGCEKISELLGLDQTALDFSSEREER MRLERDTAWSALFHSIDVKYQVWKLGVVFIDNSFLYLAWYMTMSVLGHYNNFFFAAHLLD IAMGFKTLRTILSSVTHNGKQLALTVGLLAVVVYLYTVVAFNFFRKFYNKSDDDDTRDMK CNDMLTCYMFHMYVGVRAGGGIGDEIEDPAGDEFEVERVVFDITFFFFVIVILLAIIQGL IIDAFGELRDQQEQVKEDMETKCFICGMGSEYFDKVPHGFETHTLQEHNLSNYLFFLMYL INKDETEHTGQESFVWKMYQERSWEFFPVGDCFRKQYEDQLG NT seq 14889 nt NT seq  +upstreamnt  +downstreamnt atgactgacacaggagagggagatgaagaataccagtttttaagaacgggggatgacgtg gttctgcagagtacgttcacctcccaggatgaacatgtgaagctctgtcttgctgctgag ggatttggcagcagactctgcagacttgagcccacctctaactgcaaaaatgttccacct gagttgtctgtatgtggctttgtcctggcacagtgtctctctgttagagcccttcaggag atgctggcccacagccaacacctgtctacagaaattgacataaccaaacaaagctcccag gtgggagctggaggaagccaacgcacccttctgtacggccaggcagtgttgttccttcac tcttatagcggcatgtatctcagctgcttgtcttcatctcagtcttcagctgacaagttg gcttttgatgtcggtctacaggaggataaagcaggtgagacatgttggtggactgtccat ccagcatccagacagcgatcagaaggggagaaagtgcgtgttggagatgacctcatactg gtcaacgtgtcttctgagaggtatctgcacctgtcctttggcactgtttttgacaacaaa agcttgagtgacagcctgattgttaatgcagccttccagcagactctctggagtgttgct cccatctgctctggaggtggagttgctcaaggatatctgaagggtggtgacacattgcgg ctactccacagccacagtgacgcatgtctgactgttccatccatagagaagggagaggag ctgcaaaggatcatgcattatgagagtggatcagtctgcagccatgcccgctcactctgg aggctggagattcttcgtgttggctggtgtggaaggcatacttgctgggggcagcctttc cgactctgccatatgaccactgggaggtacctgggtttgacagaggagcgaggcctgcat ctggttgatcgggacagagctgatgtcaacacaacatccttctgcttccgctcttcaaag gagaagctggacactggcaaaaagacaaatatggaaggcatgggaaccccagagatcaag tatggagactccatttgttttgttcagcatgtaaactctgggctctggctcacctaccaa gctattgatgccaaaactacacgcatggtagtggctcagagaaaggccattctgcacagc gagggtcatatggacgatggactgacgctgtcccgttctcagaaggaggaatcccacact gccagactcatccggagtgctactctcctcttcagttgctttatcaggaaattggatgtt tctagtcaaaacgaacacgtcatgtctgccagtctgccaatggagaaagtcacacaaagt ctgcaggatctgatcgactatttccagcctccagcagaaggacttgagcatgaagctaaa cagaacaacttggcagcactaaagaatcggcagaacatgtttcaggaagagggagtgtta gacttggtcctggattgtattgaccgtctgcaccaatatagtactgcttctcattttact gaggctgcacagattgacacaggcggagagtgggagacgattctcaaccgtttctatgag ctattggctgctctgattagaggaaaccctgtaaactgtgcacatttttcagcttctcta gactggcttattagcaaactggaacgactggaggcgtcttctggagtcttggaggttctg cagtgtgtcctggtggaaagtcctgaagcactcaatgtcattaaagagggacacattcat tcgatcatctctttcctggacaagcatggatgcaaccacaaggtgctggaggtgctgtgc tctctgtgtgtgtgccatggtgtggcagtgcggtccaatcaaaacctcatctgtgacaac ctgctgccagaccgagacctgctgctccaaacacgtctgactaatcaggtcaccagcatg agaccaaacatcttcttggctatgggggaagattcagcccaacaccggaggtggtacttt gagctagttgtggatcatgttgagtccttcctcacacctgagcccacacacctgcgtgtt ggctgggcatgcacagagggttaccagcccaggcccacagggggtgaagcctggggaggt aatggggtgggagatgacctctgctcctatggatttgatggacttcacctctggtcaggc tgcatgggccgcagagtgagctctccactccctcacctgctgaaagatgatgatgtggtc agctgctgccttgacctcagcgctccctgcatctccttccgggtcaacggtcaacctgtt cagggcatgtttgagaatttcagcggagatggactgcttcatcctgtcgtcagcttttct gccggagtcacggttcattttctgtttgggggtaggcatggagagtttcgtttcctgccc ccaccaggttttgctccatgctctgaaagtttgctcccgagagttaagctaaaagtagag ccctgtcacacatacatctttgatcatgacaaagggaaaaaagagctcattggctccttg gtacctgccactccagccacctttactcccatgccaatggatatcagcaaggtggtattg cctgtacaacttgagggtatccgagataaattggcagaaaacatccatgaactttgggca atggacaggattgatattggatggacatatggacctgtgagagatgaaacaaacagacac gatccctctctggtggagttttccaaactttcagagcaggggaggaaccaaaaccttcag atggctcaagacactctcaggactctgcttgcctttggtttccacatgggcctgactgat tccagcgctgaggaaagagtcaaatacacgagagtggctgccaagtatgagcagcccagt ggctataaacctgccccactagacctaaggcaggtttttctcagcccaacccatgaggaa ttggttaacttgctggcagagaatgatcacaatgtatgggccagagagcgtatcaagcaa ggatggacctacgcagcccaacaggatgtgaaagccaagcggagcccgtaccttgtgcca tacagtcttcttgatgaaagaagaagaagagtgagcatggagagtgttagagagactgtt tgtaccctgttagcttacggttacagcctggagaccctcaaccacaaaacgaccttatta tcaaacccttatcatttctctgtggagaaaggcagagtgttcagaccagacaaatcatac gctgtgacccaggggaagtggtactttgaatttgaaatagtgactgctgggaaaatgaga gtgggctgggctcgacccgactatacaccagataaggagctcggctcggatgaccaggca tttgtctttgatggatttgaggctcagtggtaccatcagggtgttgagccactgggacga ccatggcagagaggtgatgtggtgggatgcctggtggacatggctgaatgcacaatgatg gtcacgctcaatggagagatgctgtttaatgacagaggatcagaactggctgccaaggac ttcgatgtcagagacggtttgttgcctgtggtcagtgttgaggtgaaccaggtggggagg ctaaaccttggtcgccaagtggactctctgcagtactttacagtgtgtggccagcaagag ggttatgatccttttgctgccaacatgtctagagacccagccctgtggatgagttggaag cagcctcagtttacctccatactgcctgataatcataatttacaggtcaccagagtcagt ggctcgacagattccttatccagcctgagggtttctcagcggttgtttgcacaccatggt ggaggcagtgagataggcttttaccggctcagcatgtccattgaatgtgctgctatcctt aagagccctgcagggggcgtgcttcctgtggcctccaactctctctctccaggaagaaaa gatcaggaggaggtggactctgactttgaagttttgatgaagtcagcccacaattttgcg ggctcaagagatgagctcaatcataaggatcatagtcacgacaaaacctcaagactgaaa caacgcttcatgcttaagaagaccaaaccaggcctggtcaacagcaactcctccgcacgg cttctggaagatgtcgtcgttgacaaggataatcacgatcaccttattcagagctccaga tattattactcagtgagggtcctccccggtcaggagccgttcaatgtttgggttggctgg gtaacatcgaactttcatcaacatgatgtcacttttgatgctgacaatgtccaaactgtg actgtcaccctgggagatgacagtggcaaagtccaggaaagtgtgaagcgttgtaactct tacatggtttgtgctggagaggcaacaggtctgtctcagagtcgcagaagtgcagggctg gaaattggctgtttaatcgacacgtccactgggctgctcacgtttacctccagtggagta gagatggcaaccttctatcaagttgaggccggttcaaagctgtttcctgctgtttttgtg aaacccaccaccagcaacatgtttcagtttgaacttggacgcgttaagaatgtgatgccc ctttcagcaggtttgctgcgcagccaaagaaggaatgcaactcctcaatgtcctccgagg tttcaggtgcagaaactcagcccggttttatggaccaggataccggactgcacacttagg gtgatggtggatcggccagatgagtgccatggatggagagtccaatgctctgagcccctt caagtcatgtgtcttcatatccctgatgaaaacaggtgtgttgacattttggagctgtcg gaacgtgaagacctctttacatttcaccaacatactctcctcctgtactgctgcttatgc gcccttggaaacaccagggtttgtcatgccctctgcagtcacgtggaccaatcccagatg cttcatgtcatccagaatccccacctccctgggcaactccgctctgtattttaccagctg ctgactcaggttcacctcagcagccactttacggcatgtcttatgatgaaccaggaatat attgtacctatgactgatcagaccagagaaataacactttttccgagccctgctaatgca ggtaacgctcaacctccagatgcaaggcaaggcattcccagctcttgttttagcccatcc cttaaaccacagatgcacttctcatctccttgttttgtcaggagtgatggtttggaagga gattgtgcagttgaagtatcctgctcagacagcccagagatccctctggacatagtgaaa aatctgactgtagagatgctgactactggagtgtgtgctgtgggtcagggtgtgagggat cctgtaggaggcagcattgagcttctgctggtccctctaattagactgttctacaccctg ctggttatgggggtatttggggatgaagaccttgggaaagttctgagactgatagagcca cgagtcttttcaatagatgctgaaacccctgaggaggaagaggaagaagaattgagtgat gatgaaaaagaatggaaagggggacagaataaagacggtgaaagtctgaaacagggactt ctacatatgaagcttccagaggctgtcaaaattgagctctgctatcttctgtcctacctg tgtgactgccaagtgcgccacaggatagagtctgtcattgccttctctgacaactttgtg ggtcaactgcaggagaaccaaagctttcgctacaaccaggtcatgcaagcactcaacatg tcagccgctctcactgcccgcaagaccaaggagttccgctctcctccgcaggagcagatc aacatgctgctgggcttcagacatgatgagcagcaggagaactgtccctgccctgttgaa attcaacaactcctgcaagactttcatcaccttctcaacacacactgtggaattgaaacg gacaatgacgcagaggatgaagaggttgctgagatgtcagtaaaagatcgacttctcagt ctggtgggaagtgtccttgggttgaagaagaaacccatagaggcagaggagagtaggctg cagagtgccaagtccctgaaaaagctcatctctgagacaatggtgcattgggccaaagag actgagatggaggaccctgaacttgtaagagccgtattcactttgctgcatcgccagtat cagggcctagaggggcaaatggcgggacccctctccagagcctatacgatcagccagatt tcagaagaggacaccatggcactcctctcctccctgagccaaatccgttcccttctcagt gtccgaatggggaaggaagaggagaggctgatgatcagaaaactaggagacatcatgaat aataaagttttttaccagcaccctaatctaatgagggctttggggatgcatgagaccgtg atggaggtgatggtcaatgtcttgggagaaggagaattaaaggagatcacctttcccaaa atggtggccagctgctgtcgtttcctctgttatttttgccgcattagccgtcacaaccag ggagccctgtttgatcatctcagatacctgcttgaaaacagcagcgttggacttgcttca ccatcgatgcggggagccactcctctggatgtagcagcagcctctgtaatggataataat gaactggcattagcactgaaggaacttgacctacagaaggtggtgcagtacctagctgac tgtggtctccagagctgtcagatgctcgtggctaaaggctatcctgatattggatggaat cctgtggagggcgagcgttatgttgatttcctgcgttctgctgttttctgcaatggtgag agtgtagaggagaatgcttatgtggtgttaaaactgttgattcgtcggcctgagtgtttt ggccctgcactgcgaggtgatggtggaaacggtctccttgcagccatggaggaagccatc aggatctcagaggacccttctatggatggaccttgcaccatgtaccagtccaacagaaca ctagatgtggtccaggacaatgatgatgacctcattcacatggggcacgccatcatgacc ttctactcagctcttattgacttgctgggccgctgcgcgcctgagatgcatttgattcaa ggaggaaaaggagaagctatccgtatcagggccattctgaggtcactcatccccatccag gatcttgagggagtcatcagcatttcctttgaaatcccttcagtggctaaagatggtctg gtggatgagccagacctctctacagtgttctgtcctgaccacaaggcagccatggtcttg tttctggaccgagtttacggcattgagaaccagaattttcttctccacctacttcaagtt ggctttctgcccgaccttcagacagccgtgtctcttgacgctgctgacttaggctccact gatatggccttggccctcaacagatacttgtgtacatctgttcttcccttgctcaccaaa tgttcagatctcctctgttctgttgaggaccatgcctcgctggtggatgctcttatccag gcaatctacaacctctcacgggctctcagcctgaccaaggctcagcgagacactattgag gattgtttgttggcagtgtgcagtaaactccaaccatctatgatgcagcctcttcttaga cgtctggtcttcgatgtccccaagctcacagactacagcaaaatgccgctaaagctcttg acctgtcactatgagcaaaggtggaaatactactcgctagcagggggacaggatgaccag agttctgcctctgaagaggagctccacctgtccagaaagctgttctggggtgtctttaag gccttggcaaagaagccctatgagcctcagttattcccactctgtgttcaaagcctagct gctgtggctaaggccattcctcctgaccacatggactcgagctgcacgcctcatagtgag agaaaagcctccacagacacagaaggacactttgaacttcagcctgtagatacatccaat gtgtcagtgccagagagactggagttcgtggttaataagtatgcagagcacactcacgag aagtggtcactggacaagtttgccaatggttgggttcatggagagcagctctgtgagaac actaaggttcatcctctcctcaagccatacagggctctggctgagaaggagaaggaggca taccgctgggccattaaggagacgataaagagtatgctcgcctttggatggacgatagag aggactaaagagggagaggcatttggaacacatacctgttcacgcagagtctctcagtct ggacagctgtcgtttgagggagcatcaacttttagccccaagtctttggacatgagcagc atcaccttatcgtgggaccagtgtgctatggcggaacatttggctgagaactaccacaat gcctgggctaagaagaagaaattggagcttgagagtaaagggggtggccattcaatgttt gtaccctatgacaccctgagtgctaaggagaaaaccaagttcagagagagggcccaagat atcctcaagtttcttcagcttaatggctacactgtgtggagggatcggaggactggggag ttggaatttcaagctgtagccaattgcttcagctacactcttcttcggcgcctgctgtct tacactgaggagtgtcaggagcacatgctggagctggaggtgatgcaagccagaggacag atgtctaaaggagagagagctccacaacagcaactattaaattttttttccaaggttgtc cttcctcttttggaacaatatgtgaagagccatcgtctgtatttcctgtctacttctctc tgctcaagcggaaatcaaagccatgcctcaaaaagagaaaaagagatgattgcaagcctc ttttgtaagcttgcaactctagtgagacacaggatctctctcttcggtaacgaaggctca caagttgcaagctgcctccatgttttggctcaggctctggatgctaggacattaatgaaa tcagccccagagtctatccaagcgtctctgcactcattctttgaagcagctgcagctgac ctggagatgatcgtggaaaacctctctgtgaccttggtctgtttacctcagagtaggagt cagcaggctaaaggagtggccaaggttctcagctacagcagctccattcttgtgcccacc ctcacttctctctttcggcatctttgcatccaaaactttggcgaggacctcctgttgggg agtatccaggtgtcctgttacagaatcctcaacagcctgtactcacttggcaccagtagc agcatctacatggaggggcagaggccagcagcaggtgcttgtctggcagccctgactggg actttccctgtatgcttcctggagccttcctataatcataacaacccctactccatttac aacaccatgaatgcttctgaaagagaagacctggggcttctcgatcaggttgaggacatg tgtcccctcctgccctctctggatcaggccctgggggaggtggaggagttggcatgtgct ggtgctggcgctcgcctagccccttacatccatgtcacagaggtcaccttgcccatgctg tgcaactacatgtctctctggtggcactggggcccagagggacagcaagaaagcccaata tgcacctctatcacttctcagcatgcaagtgacctacttggccacatcctccgtgttatc cacaaccatgtgggagctagccagtgtgagtggatgaaacagctggcagttttctctcag cctatcatatgtaaagccaactctgagctgttaaagagccactttcttccactgatggag aagttgaagaaaagggccggatgcgtgctgctggaggaagagcagatgaaagcagaagtg tgtgatacatctgaagcagagctgcagctacaggagaagtttactgtactggtgcgagac ctttacgccttctacccccttctcatcccatttgtggattctaatcgagccagctggctg aaagagtcaaaccctgatgctgagcagctgttcagcatggtggcagaggtcttcactttc tgggccaaatcacataattttaaatgggaggagcagaactatgtggtccaaaatgaaatc aacaacttggcttttttagtcaacaaagacaacatgtccaagttcgaccatgacaaaagg aggatgaagaggaagggggactgttattccacacacacctctctcatagtggcttctatg aagagacttctccctgtgggactgagggtttgttttcacaacgaccagatccttcttgtg ttggctaagaagggcttcacccagaagaagactgaggatgagattcgagaggatgttttc aattacctcaaccatcttcagagtgagacttcaaactgctttgggcaggaggctgttaat gcagtacacccacgcctgtttggggcaatcgctgaaaccaaagagactgttgacaagatt ttggaaattgcacgtgtcctgtattacctggatcaggtcgaacaccctcagaaaagtaaa aaacctgcttggcacagggtcttatccaaacagaggaaacgagcggtggtggcctgtctg agaatggctcctctctacaacctaccaaggcacagggctgtcaacctctttatccaaggc tacaataaatcctggatatctgctgaggacctcagctttgaggagaagcttgttgaggat ttagctaagggaggagtgacagagttgtgtggaggcgacagagaggaagaaaaggatgtg ggagacgttgccaaaccaatcgatcccctcctacagctcattacactcttcagtcgaagc gccctgacagaaaggagaaagcttggaaatgacagtctgtataagtcttatgcttcaatc atggcaaagagctgccaaagtgaagacgctgatgatgaagagcaggaggccaaaagcttt gaagagaaggagatggagaaacagaagctgctttaccagcaggccaggctgcatcgtcgt ggagcttctgagatggtcctccaaaccatcagtgccagcaaaggggccatgggtgcgatg atcgcccccacattgaagctgggcatatctgttctgagtggagggaatgccactgttcaa cagaaaatgctggattatctgagagcgaagcaagatgttggcttctttcagagcatggct ggactaatgctgtcatgtagtgttctggatctgaatgcatttgagagacagaacaaagct gaaggattaggcatggccatggatgagagctcaggagagaaggtgatgcctgacaaagac gtaacctgcgacctgttccgttttttacaactgctctgtgaaggacacaactcagatttc cagaattacctgagaacacaaacaggcaacaacaccactgtcaacatcataatatccact gtggactatttactgagagtgcaggagtcgatcagcgacttttactggcactattcaggg aaagatgtgattgatttccacggccaacaaaacttctccaaggccattgaagtggctaaa caggtcttcaacacactcacagaatacatacagggtccatgtaccgggaaccaacagagt cttgctcacagtcgcctgtgggacgctgttgtgggattcctccatgtctttgctcacatg cagatgaagctctctaaggactcaaggcaaattgagctgctgaaggagctcatggatcta caaaaggacatggttgtgtttctgctttccatgctagaaggtaacgttgtcaatggaatg atcggaaagcagatggtggatatgttggtggagtcatcaggaaatgtggagatgatcctg aagttttttgacatgtttcttaaacttaaagacctcacctcctctgaagcattcagggag tacgaccctgatcataagggatgtatctccaggaaggacttccagaaagcaatggagaac tgcaagcgtttctcacaaactgagactcacttcctcctctcctgctcggaggctgacgat agtgatattgtggattatgaggcgtttgtggatcgcttccatgagccagccaaagacatc ggcttcagcattgctgttctccttaccaatttgtccgaacacatgccaaatgatataaga ctaaggacattcctggaactggcagagtgtgtcctgacttacttccagccctatctggga cgtatagagatcctcggcagtgggaagcgcattgaacgtgtctactttgaaatcagtgaa tccagccgcacacaatgggagaagcctcaggtgaaagagtccaagaggcagttcattttt gatgtcgtcaatgagggtggcgagaaggagaaaatggagatgtttgtcaatttctgtgag gacaccatctttgagatgcagcttgctgcccagatctctggctctgacactggagagagg tgtgttgaaaaagaagatgggagtgaagacgaaggtcatgacaacaaaggaattttcttc ctttatcagtggatgttgttgctgacatctttactttctgtcaaaaacctgaaattcata atgaagatgtcattgaaggatatcctcatgtcagctcttttcttgctcagattcattgtt atggctcaggttcggtgtgtttgtgccgtggttcacagcatcttatatgtgctgtatata gcttttgtcagtggtgggcttatagaggcagccaaaaggatgaaaatatctgacttgctg ggtgggatcctggaaccaactcttgatgaggtcatggaggtgccaagcggtgtggatcgt ctgaggaagtaccctggcagtttttcttcccagagagagttgagggaggttgggcaggag gcagctgtgacctcccccagggacgtggatgtactgtcagacatatttggcctccaagtg aagaaagagggaggtcaatacagacttataacacaagacctcactgccagtctgtctgac ctgttcaacacagcctccagagcaatttccaccactgatttttctgagaagcagcagcag cttaaagcccacaccgccacagaggaaaaaccagaagatgaggaaatacatctcacaaaa gggaaggaatctgaaaagaaaacggggaaggaggaagctgaagcagaattaacatccaag aaatgctctcacaagtcggaggaaaaggatagccaacggtctgctctcttggagattata agcactcacaacaagagcctgctgaattattttgcaaggaatttttacaatatgcggttg ctggctttgtttgtcgcctttgcaatcaatttcatcctcctcttctacaaggtcgcatcc ttgcctgcatcacaagaagagaaagaagtgatcgcatctgattatactgaggaactgagc tctcctgctgaagatgacaatgagggcaaagtttattttgtgctcgaggagagcagtgga tacatggagccgtcactccatttcctggctgtagcacacacagtcatctccttctgttgt atgattggttactactgccttaaggtaccattggttattttcaaacgtgagaaggaagtg gcacgaaggctggagtttgatgggctgtatgtgacagagcaaccgcctgaggaggacatc aaagggcaatgggaccgactggtcataaatacaccatcctttccgagttattactgggat aaatttgtgaagaggaaggtgatggataagtacggtgacttctatggctgtgagaagatc agtgagctcctgggtctggaccaaaccgctttagacttcagctctgagagagaagaaagg atgaggctcgagagagatactgcctggagtgctctatttcactccattgatgtgaagtac caggtctggaaactgggagttgtgttcattgataattcctttttgtacttggcctggtac atgaccatgtcagttttgggccattataacaacttcttctttgctgcccaccttttggac atcgccatgggctttaagacacttcgtacgatcctttcttctgtcacacacaatgggaaa cagttggcgctgactgttggcctgttggcggttgtggtctatctctacaccgttgtggcc ttcaacttcttcaggaagttctacaacaagagtgatgacgatgacacccgggacatgaag tgcaatgacatgctaacttgctacatgttccacatgtatgtgggagtgcgtgctggcggg ggcattggcgacgagattgaggacccagctggagatgagtttgaagtggaacgcgttgtc ttcgacattacatttttcttctttgtcatcgtcatcctcctggctatcatccagggcttg ataattgatgcctttggggagctgcgtgaccagcaggagcaggtgaaagaggatatggag accaaatgttttatatgtggaatgggaagtgaatactttgataaagtcccccatggcttt gagactcacactcttcaggaacacaacctatccaactatctattttttctgatgtacctt ataaacaaggatgaaactgaacacacagggcaggaatcctttgtgtggaaaatgtaccag gagcgttcctgggaattctttcctgtgggagactgtttccgtaagcaatatgaggatcaa ctgggatga

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