Labrus mixtus (cuckoo wrasse): 132983612 Help Entry 132983612         CDS       T10666                                  Symbol pkd1a Name (RefSeq) polycystin-1   KO K04985   polycystin 1 Organism lmix  Labrus mixtus (cuckoo wrasse) Brite KEGG Orthology (KO) [BR:lmix00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    03037 Cilium and associated proteins [BR:lmix03037]     132983612 (pkd1a)    04812 Cytoskeleton proteins [BR:lmix04812]     132983612 (pkd1a)    04040 Ion channels [BR:lmix04040]     132983612 (pkd1a)    04091 Lectins [BR:lmix04091]     132983612 (pkd1a) Cilium and associated proteins [BR:lmix03037]  Primary cilia and associated proteins   Other primary cilia associated proteins    132983612 (pkd1a) Cytoskeleton proteins [BR:lmix04812]  Eukaryotic cytoskeleton proteins   Intermediate filaments    Intermediate filament-binding proteins     132983612 (pkd1a) Ion channels [BR:lmix04040]  Voltage-gated cation channels   Transient receptor potential channel (TRP)    132983612 (pkd1a) Lectins [BR:lmix04091]  C-Type lectins   Others    132983612 (pkd1a) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PKD REJ PKD_4 PLAT Polycystin_dom PKD_channel LRR_8 Lectin_C LRR_4 WSC GPS LRR_LRWD1 Motif Other DBs NCBI-GeneID:  132983612 NCBI-ProteinID:  XP_060905981 LinkDB All DBs Position 2:8792584..8864514 Genome browser AA seq 4683 aa AA seqDB search MPCGNGQTLSKRKHGVCVPRFSFFSSLLLALCCLEVWCSGTRGDGGTSCSPCPVNCSCVL AGPLHSCVVNCSNIGLERAPAAADIPEATNVLDLSKNHISSLDTSLLDRLTGLRELYLQG NRINILPRGVFCCGPISILDLSNNLISTIEERTCDNLCNLTQIDLSGNPFECDCELFKLV RWLQERGVRVRRPDAMLCNQPPELRHQPLLNVSLHTCGPNFAACLEDSSSGGGGRSELVI FSSSTPGNFTREQCNSVCFAASHLYGGLGTKHECLCSINSEPNFISESQCSAACTNPDVM KKCGWTLAHDVFAVDFSVSLKPLPLQSVHDRIAFSAASSVTPLTLSWDFGDLSTRVNTTG TEVTIATHKYGLPGRYAVSLMAWAGHKEVSARGEVTVTLPPKLELHCPVLAVANKSLEFK LVSWGAVGVEVDWKIIKDGVQVAKAAPHCPKDGVYHAESSRCFQIVPGQLSWTDARQQCL DRSGDLAIVRSDALRNLLAPRVTQDRGVWLGLSNVDSPGKLRWVNGSEAEEGEEGLPHRS TTPPGNLCVSLDQKGQASSHLCNAKRAFVCQYSPQVPVPDAGVYVSGLTVFPTHKPLQHI PTAALSTPQPSSSGIEVLLFPALSFVQAGRLSSLEFVTKELSSPVHVRFQTYSPHCHYPG HHLLLPSCGGQACAPVAVCVINDTNSSDPPSCPRLEQWCPFHRRCLPLSSPCHPSSCPNC TQTHRLPPGALRPRYTLKYEVVFTLPAGPAAHILVQEDLEDILVSPGDVIALQHDAGPAS LLQCQSSPHSLWRQPVLALNQSDWFWINNTRHQTDPSADHDSDPVPDPELDIEALVKDGE GGWMEEVVCPVRVLYVGQSETQLKGGQLSAGLPQPGLYSLMVTTAEPSYHASASCPLRVV PPLGLTVLHPPSRNSTLYLQSNDTRLLLRVQSRYVTTVSLHGSNRSAVFQPDCSPEFSSG PALCRPSPSSGSGLDVAEPSLYAVLDLSLRSEEQKGPMQVELEVYNNVTEASLTLVVQLE EPLRGLMVQPHPAHRVLMESVVSYTASVLEGSSPTFKWTVDDKPYFTYYNTVLNVIYQHP AVYKLTVTAMNHVSSLTEHFNVTVDRMQPMANLTVKGVPDVVPQGSTQTLTTTVLLDMSV AATFRWSFGDGGYKEFEFKPPYSPSLLCSESPNQVLLSNNVTYIYSQPGIYTALVSVSNR YENISQSINMSVYSILTRVDIQTEPPLLLTGKAADFEAHPLPSPYGIHYDWHFGDASSPQ QGRRVAHTFAQSGVFNVCVSVNNTISSTKECAEMFVYEEIENLTVESSSPTELHSSTTVW AHLASGNNITWTFSMGDGTIYTTSAPHVSHSYRKDGNYTVNVTAMNAVSSGWTLVPVQVF VFQVVKMEPSGCVQERTPVNFEAWVSGNASAHHYEWSFGDGSPNETHHGNPRVLHTYLTS GNYHLSLLLSSGINKDTKANFFNWVCVQPSLTTISLKLEKTQYAVGEEIQFQARAQPEFH YGYKWDFGREEDFLPNHGSEKMVTTYKNPGRYIVSVIVFNNISTINTSVVFDVLTPLGPI LIQHNGTKFNNLTLGAPHYFTTSSTASNVTYVWNFGVGNVIKGQNVLHTYKTSGIYNVTL TAANTVSRNVTSLPVAVLAPILGLTINASLVNVPLNASVHFEAQMVEGDGVRFSWILCDR CTAIIGTHTMFYTFRSVGTFNIIVTAENDVGTAQASIFLFVQRELEGLQILAEEDTRGDG GRGLEGFYFATNRVLHLNAGLKEGTNMTFTWNLIRELDPASSSFNISLKTVEVNFSTPGR CDIILQAANLLGQLSVNRTINFLDPVGHPHLEISNKKIAINASTNLTVLTPEGSDLQYRW SVNGDVLQWNEPWKTQSFSSPGLKLVTVEVFNEVSSEIVSEVLSVQELISGLSFSATNVT EQGYVATNVSLVLEGEVLTGTNVTWTWLLEGRTETGRKTSLIFNEPKTAVMSLNASNDVS GQLVSREFFVQDKIQGLELRASKKCAAVGEKVEFTFSMGAGTDVSLILSISGDATVIPQP NQNYVHTFSRVDTYMVNLTAHNQVSSQRRNLQVQVMEPVSGLSITGISAAIPVGEKRFFV ANILTGKPVCFLWTFDLHKLHKTTIFGKEVSYTPEVEGVLTIHLKAFNSLPSQYITKYIL VQNLLTAAVLYATPRDTFINKTVTLSTYVTPSSNSVECLWDFGDGSSPVHTNNTTVDYNF KNPGHFLVKVNCSNLVSWVLAQVEVNISVLECEEPEVHVVQAPRLPIWRYQPSLVEASVD LKGCLRYGAQYLWQILSTPSCDDDKNHVIPSGMESQPSRSLMKPIIRLPVEVDVQRLQLS LPKMALPTGNYTLVFSLSYKGVPLRKAACIQLSVMAARLMPIIEGGTYRVWSRTQDLQLS AEQSYDPNMDPDSQSLLHYHWECQSTSKGPEHCSTLNFGLGSSGPVLGISGSELEAGVEY TFRLTIIKDGMAPESTTQTVLVQSGHIPMVYLECVSCKAQSIYEVSKNSYVYLRGTCTNC QGFHRGRWSAMTPKNETLVLDSSSTTTGSDGMNLVLRQGVLQHENSYIFTLHVTDGTLDG EGAASITLHHNMPPSGGECHLRGGGETGMEYGDAEVEGLRIRTLLDRVHFNCSGYSDLGV SETPLLYSLLVTRCREDYCEDFCVYKGSSPEHSVFLPPGFSSARNRLAVSITVEDHQGAA SLALNKSIEVVLPDPPPEYNSLPHWLSELTDTTLKKLLEQGDSQRVRELSLAFITVLNEY EQTRKSVRVSRDERSDRVRVRSNITRALTALDLTTVSDIQQTSAALAQCTAVSREFICEE CQNSTLSKLESMLEILQTDTKQGTVTPTEIADNILNIMGDLIHQVSQSASQSYFQPPYMD SPSPHFTSSFSTISEDQGGPLLDPSPSSLEPHPLRVAAKAFSLSSVLMLILMHARVLNEE PLVLRGAEIAATGKLADPQSLLCYHGNDSPECQRFSIPRAFNSCLDKAAAGNSIMQLLFQ VESNPFPFNYVENYTVSTEVASMEFRTENGTQIPISGLDDSLAITVAINNGSSAAEAGPE GAGTGGVPTAGAVNISHCDSVIVKISAGNTNRQAGLFVQLNFTSLHGVSEKEKAEEEPYI TAYLHSHDRPNEFNCTDRKQISLSMTRGQDLDHRKYTFFLSPESYDTTLDYFINVSTTCS PSSHPLGVHLEVGVFASLCQYFSESEKQWRTDGMVPLAETNASRAVCRTRHLTTFAAGLF VPANAVSFKVPERYGPPSLVVLLVCVLGLLSYVVAAAILHKLDQLDLRRAAVVPLCGGEG LFKYEVQVKTGWSRGAGTTAHVGISLYGRESRSGHRHLDSRGAFTRNALDIFHIATDTNL GSVWKIRIWHDNKGLSPAWMLQYVLIKDLQTGSSYYFLVEEWLSVDNEKTDGRVEIELEA SEEALLLEMPRLLRCELQRALCESHMWLSLWERPPRSPFTRLQRATCCAVLLQLFVFANS LWYSIVVDKRYSSQAVSRLSSLNGETVAAGVVTCLIVYPLYLLVFTVFRMSRSKCVTVEQ VQPQSDQESVEIDDFLENSMNGSSFLFFNGETNSEETNLDFPTPSTKSVESWAMAEEEME DRDWPEWLSDGSVVGGAGHGAGMPRLKRGQGSRHLGVDMAFNPDDEEGTGERNKYFTSSD EDLIKHILTDGQNFFPQADESEMADLSSILDDKTEVILLQRPNEFLPPGALRRPKTAFTS NTVVTDVCRPRRFPPWCGRAALWGSWAGIALASGVSIWAGHGFSQNVAMMWLISCFSSFL SSCLVLEPIKVLCEAVYYAVYVQRLRPEDQDVLVEFPRVERVVQRVPRVRPPQGFALSQA RHQARKVHMLYTMLKNFLVYMFFLLVVLLLNYSDSAKDTHGLRLRTQLQRALHAPEYHNI SSRGDVLLWLNGSLLPRLLDDTALLRDTGSVLLGTLRLRQIRDTQDALGSWAGESDQGKE QSLSQGAENVSAFGANNTKWGWRLDVYNSGDVVQQLNRSLAQASSSLQQLQQLHWLDYRT RALFVEFSLYNVNTNLLAVFSFLFEFPVSERAQSSLDLFVISLWPITGLDLQLLLMTVLM ALVLYFLVRGILGFLREGHVYLFSAWRLLGICKLTLAASVCGLHLSRCTMASQQWASYLK HPRDAFTDFYPLARQSQMYTVMSALLLFILVLKASHQLRFLREWAVFGRALRCSVWELLG VALALLLLLLAFSHTGHLLFHSVLDGYGSVSSASQSLLGAGGRGLLSWRPTWMTTGPSNT VTSLMFHASFAILRLVLLWLLTSVLLRNYRRARAELYRPAGDLQDYEMVELFLRRLKMWM GLSRAKEFRHKVRFEGMELPPSRSSSTSDCKSLCLPPLDRPDSPSTPDSVDGGSEASWRP TSSSPCSLTEAPGIGLGLGLGLGLGLGPGVVMGSTSWRERAETEASLRRLLPTLDALLQQ LDRVTIATEDLYHVECKMERSQRKKRSRGREKGDSGGQGGRSEAGHRAKGEEKDATGWRD RKTGKEKQKGSKKGKKTDKSELRKDCGNTSANPKKTTEATHAPLIKPQPSPATTQTPAPQ SSTKPLASAPPPTPVKDKSASGFSSPVSSANTPPSRVPLPKTPTAPPCTPAPTSSSFSTP APTPVGGDWDPPTERETFPSSSLFNHPAHTTTIPTRKRKRKPPPLKNKVHPNLDRQGPGH PKP NT seq 14052 nt NT seq  +upstreamnt  +downstreamnt atgccttgtggaaatggacagactttatccaagcgaaaacatggcgtctgcgtcccgagg ttcagcttcttttccagtcttcttttggcgctgtgctgcctggaggtctggtgctccggg acgcggggggacggcgggacgagctgcagcccctgtcccgttaactgcagctgcgtactc gcggggcccctgcactcctgcgtcgtcaactgctccaacatcgggctggagagggcccca gctgcggccgacatcccggaggccaccaacgtgttagatctttccaagaaccacatctcc tcccttgataccagcctgctcgaccgtctcactggcctccgagagctgtatcttcaaggg aacaggatcaatattcttcccagaggcgtattctgctgcggaccgatctcgatccttgat ttgagcaacaacctcatcagcaccatagaagaaagaacatgtgacaacctgtgcaattta actcaaatcgacctgagcggtaaccccttcgagtgcgactgcgagctgttcaagctggtc agatggctgcaggagaggggggtacgggttcgacgcccagacgccatgctttgcaaccaa ccgcctgagctgcggcaccagcccctgctcaatgtcagcctgcacacctgtggcccaaac tttgccgcatgtctggaggacagcagcagtggtggaggtgggcggagcgagctcgtcatc ttctcctcctccacaccggggaacttcacacgtgaacagtgtaacagcgtgtgtttcgct gcgtcgcatctctacggcggcctgggcaccaaacacgagtgtctgtgcagcatcaactcg gagcccaacttcatcagcgagtcgcagtgttctgctgcctgcaccaaccccgacgtcatg aagaaatgtggctggactctggctcacgacgtgtttgccgtggacttctcggtttcgctg aagcctctgccgctgcaaagtgttcacgaccgcatcgctttctccgccgcctcctcggtc acgccgctgacgctgtcctgggactttggtgacctttcaacccgagttaacacgacaggg acagaggtcaccatagcaacccacaaatatggacttccaggacggtatgcagtcagtttg atggcctgggctggccataaggaggtctctgcacgtggagaggtgacggtgactcttcct cctaaactggagctgcactgtccagtcctcgctgtggccaataagagtctagagttcaaa cttgtcagctggggcgctgttggtgttgaagtagactggaagatcataaaggatggcgtc caagttgccaaagccgcccctcactgtccaaaggatggggtgtaccatgccgagtcctca cgctgtttccagatcgttccagggcagttaagttggacagacgctcgacagcagtgtttg gaccgcagcggggatctggcaatagtcaggagtgacgcgctgcgtaacctgctggcaccc agagtcacacaggatcgaggtgtgtggctgggcctgagtaatgttgactctccaggcaaa ctgcgctgggtaaacggttcagaggcagaggagggagaggagggcctgccgcatcgatcc accaccccccctggaaacttgtgcgtttccctcgatcagaagggtcaggccagttcacac ctatgcaacgccaagcgagccttcgtctgccaatacagcccccaagttcctgttccagat gcaggagtctacgtttcgggtctgactgtgtttcccacccataagcctttgcaacatatc ccaactgctgcgctctctactccacaaccttccagcagtggcatagaggttctgctgttt ccagctctgagctttgttcaggcaggtcgtctctcctccctggagtttgtcactaaggag ctcagttcacccgtccacgtgcgattccagacatacagccctcactgtcattacccgggc catcacctgctgcttcccagttgtggaggtcaagcgtgtgctccggtggctgtttgtgtt attaatgacaccaacagcagtgatcctccgtcttgcccccgcctagagcagtggtgtccc tttcatcgccgctgcctgcctctctccagtccctgtcacccatcctcctgccccaactgc acccagactcaccgcctgccccccggggcgctgaggcctcgatacaccctgaagtacgag gtggtgttcacccttccagcaggaccagctgctcacatactggtgcaagaggatttggag gacatacttgtttcacctggtgatgtcatagccctgcagcacgatgccggccctgcctct cttctccaatgccaatcatccccacactcactttggcgacaacctgttttggccctcaac caatcggactggttctggattaacaacaccagacaccaaactgacccctcagcggaccat gactctgaccctgtgcccgacccggagcttgacatagaggctctggtgaaggacggtgaa ggaggctggatggaggaagtcgtctgccccgtcagagttctctacgtgggtcagagtgag actcagctaaaggggggacagctgtctgctggtctacctcagcccggactctacagcctg atggtgacgacagctgaaccatcgtaccacgcctcagcatcatgcccattgcgggtggtt cctcctctgggcctgacagtcctccaccctccctcccggaacagcaccctctacttgcag tccaacgacacccggctgctgctccgtgtccagtctcgctacgtaacaactgtctctcta catggcagtaatcggagcgcggtcttccagccagactgttcaccagagttttcctccggt ccagctctctgtagaccaagccccagctcagggtccgggttggatgtggcggagcccagc ctgtatgcagtgctggatctgagcctgaggtcggaggaacagaagggtccaatgcaggtg gagttggaggtctataataacgtgactgaggccagcctgactttggttgtccagctggaa gagccgctccgaggactgatggttcagccccaccctgcacacagggtgctcatggagtca gtcgtgagttacacagcatccgtgctggaaggctccagtcctacatttaagtggacggtg gatgacaagccatacttcacctattacaacaccgtcctcaatgtcatctaccagcacccg gccgtctacaagctcactgtgacagccatgaatcatgtcagctccctcactgagcatttc aacgtgactgtggatcgaatgcagccgatggccaacctcacagtgaaaggtgttcccgat gttgttcctcagggctccacacagacccttaccacaactgtgctcctggacatgtctgtg gctgcaaccttcagatggtcatttggggatggcggttataaggagtttgagttcaagcct ccctactccccctccctcctatgctcagagtcgcccaatcaggtcctattaagcaacaat gtcacctatatctactctcagccaggaatatacactgcactggtgtcggtgtccaatcgt tatgagaacatcagtcagagcatcaacatgagtgtctacagcatcctcacacgggtggat atacaaacagagcctccactcctcctcaccggcaaagcggcagatttcgaggctcaccct ctgccctcaccctatggcattcactacgactggcactttggagatgcttcttccccgcag caaggtcgccgcgtagcacacacctttgcacagagcggcgtctttaatgtctgcgtgtca gtaaacaacaccatcagctctactaaggagtgtgcagagatgtttgtatatgaggagatt gaaaatttaacagttgaaagttcgtcccccacagagcttcacagttcaactacagtgtgg gcacaccttgcttccgggaataacatcacctggacgttctccatgggcgatgggactatt tacacaacatctgcacctcatgtatcacacagctacagaaaagatggaaactatacagtg aatgtgactgccatgaatgctgtgagctctggctggacactggtaccagtgcaggtgttt gtcttccaagttgtgaagatggagccatctgggtgtgtccaagagcggactcccgttaac tttgaagcatgggtgtccggcaacgcatcagctcatcattacgaatggagctttggtgat ggaagccccaacgagacacaccacggcaaccccagagtcttgcacacatacttgacaagc gggaactatcacctctcactgcttctgtcaagcgggataaacaaggacaccaaagccaac ttcttcaactgggtgtgtgtgcagccatctttaaccaccatcagccttaagcttgagaaa acacaatatgctgttggggaggagatccagttccaagccagagctcaaccagaatttcac tatggttacaagtgggactttggtagggaagaagactttttgccaaaccatggttctgaa aaaatggtgacgacatataaaaaccctggtcgttacattgtgtcagtcattgtcttcaac aacatttccaccattaacaccagtgttgtgtttgatgttctgacaccattaggacccatt cttattcaacataatggcactaagtttaacaacctgactcttggtgcaccacactatttc acaacatcttccacagcttctaatgtcacttatgtctggaactttggagtcggaaatgtg attaagggccaaaatgtcctccacacctacaagacctctggaatctacaatgttacattg acagctgccaacactgtaagcagaaatgtcacaagcttacctgttgctgttcttgcgcca atccttgggttgaccatcaatgcaagcttggtcaatgtgcctcttaatgcctcggtccac tttgaggcccaaatggtggagggagatggagttcggttctcttggatcttgtgtgatcgc tgtacagcaataatagggacccacaccatgttttacaccttccgctccgttgggactttc aatattatcgtgacggcggagaatgatgttggaactgcacaagcgagcatcttcctgttt gtccaacgtgaactggagggcctgcagattttagcagaagaggacactcgaggagatgga ggccgagggttggaaggtttctactttgctaccaatcgtgttctccacctaaacgccggt ttaaaagaaggaaccaacatgacatttacttggaacctcatcagagagctcgaccccgcc agttccagctttaacataagtttaaaaacagtggaggtgaacttctccacaccaggccgc tgtgacatcattctccaggcagccaacctccttggtcagctgtctgtaaacagaactatc aacttcctggacccagttggacatccacacctagagatcagcaacaaaaagattgccatc aatgcttcaaccaacctgactgtattgactcctgaaggctcggacctgcagtaccgctgg tctgtgaatggggatgttctgcagtggaacgagccatggaagacccaaagcttcagtagt cctggactgaagctagttactgtggaagttttcaatgaagtgagctcagagattgtgtca gaggtcctcagtgtacaggaattaatttcaggtttaagtttttcagcaaccaatgtgaca gagcaaggttatgtagcaaccaacgtcagccttgtgctcgagggggaggtactcacagga accaatgtgacgtggacatggctgctagagggaaggacagaaactggaaggaaaacctct ctgatttttaatgagccaaaaacagccgtcatgtctttgaatgcctccaatgatgtcagt ggacagttggtttccagagagttctttgttcaggacaagattcaggggttggaactaagg gcgagtaaaaaatgtgcagcagtcggtgagaaagttgagttcactttttccatgggcgca ggtacagacgtcagtctcatcctcagcattagcggcgacgccactgtcatccctcaaccc aaccaaaactatgtccatacgttcagcagggtggatacatacatggtgaatctgactgct cacaaccaggtgagttctcagaggaggaacctccaggtgcaagtgatggagccggtgagt ggactttccatcacgggaatctctgcagcaatccctgtgggtgaaaagaggttttttgtg gccaacatcctcacaggcaaaccagtttgtttcctgtggacctttgatctgcacaaactc cacaagacgacaatatttggcaaagaggtgtcctacaccccagaagtagaaggcgtattg accatccacctgaaggccttcaactccctgcctagtcagtatatcaccaagtacatcctg gtgcagaacctgctgactgctgccgtcctgtatgcaacaccacgggacacttttatcaat aagacagtgacgctgtcgacctacgttacacccagctctaactctgtggagtgcttgtgg gactttggtgatggttcatctccagttcataccaacaacacaactgtggattataacttc aaaaaccctgggcacttcctcgtcaaagtgaactgcagcaacctggtgagctgggtgttg gcccaagtggaggtaaacatcagtgtattggagtgtgaggagccagaagtgcatgtggtt caagcccctcgcttgcccatatggcgttaccagccctctttggtggaggccagtgtggat ctgaaaggctgcctacgctacggagctcaatacctctggcagatactttcaacaccatca tgtgatgatgacaaaaaccacgttattccctctgggatggagtctcagccctcccggtct ttgatgaaaccaataattcgcctgccggtggaggtggatgtgcagcggctgcagctatcg ttgcctaagatggccttgccaacagggaactacaccttagtgttttctctgtcatacaaa ggtgtcccactgaggaaggctgcttgtatacaactcagcgtcatggctgccaggctgatg ccgattatagaagggggcacctacagagtgtggtcgagaacacaagacctgcagctcagt gcagagcagtcatacgaccccaacatggaccccgacagtcagtcactactccactaccac tgggagtgtcaaagcacatccaagggtcctgagcactgctccactcttaatttcggcctg ggctccagcggtccagttctgggaatctctggctctgagttggaggcgggtgttgaatac actttcaggctgaccatcattaaagacggcatggcaccagagtcaaccacacagactgtg ctggtgcagagtggtcatatccccatggtgtatctggagtgtgtgtcctgtaaggctcag tccatctacgaggtcagtaagaactcctacgtctacctcagaggaacctgcaccaactgc cagggctttcatcgcgggcgttggagcgccatgacgccgaagaacgagactctggtcctg gactcctcctccaccaccacagggagcgacggcatgaaccttgtgctgcgccagggtgtc ctgcagcacgagaactcctacatcttcaccctgcacgtgaccgacggcactctggacggt gaaggcgccgcctccatcactctgcaccacaacatgcccccgtccggtggagagtgtcac ctgagagggggaggggaaacagggatggagtacggggacgcagaagtagaaggcttgagg atacgcacgctgttggacagggtacacttcaactgttcaggttacagtgatcttggggtc tcagagactcctttgctctacagtctgctggtgacgcgctgcagagaagactactgcgag gacttctgcgtgtacaaaggcagcagccccgagcactctgtcttcctgcccccaggcttc agctcagcacgaaaccgtttagccgtctccatcacagtggaggaccaccagggcgctgcc agccttgcactcaacaagtccattgaggtcgtgctgccagatccgccccctgaatacaac agccttcctcattggctgtcggagctgactgacacaacactcaaaaagctgttggagcag ggagactcccagagggtccgagagttatcactggcttttattacagttctaaatgagtat gagcagaccaggaagtctgtgcgcgtgtcacgagacgagcgcagtgaccgggtcagagtc cgaagcaacatcaccagagctctgaccgccctggacctgaccaccgtcagtgacatccaa caaacctcggctgctttagcacagtgcacggcggtgagtcgggagttcatctgtgaggag tgtcagaacagcacgctgagcaagctggagtccatgctggagattctgcaaactgacacc aagcaaggcaccgtcactcctactgagatagctgacaacatcctcaacatcatgggtgat ctgatccatcaggtcagccagtctgcatcccagtcttacttccagcccccctatatggac tccccctcgccccacttcacctcctctttttctacaatcagcgaggatcaaggaggcccc ctgttagacccctccccttcctcactggagccacaccccttaagagtggcggccaaggcc ttcagcctgtcctctgtcctcatgttgatcctcatgcacgctcgggtcctcaacgaggag ccgctggtgctgaggggagctgagatcgctgccacggggaaactggcagaccctcagagc ctgctctgctaccatggcaacgacagtccagagtgccagcggttctccatcccccgagct ttcaacagctgtcttgacaaagctgcagcaggaaacagcatcatgcagctactttttcag gtggagtccaaccctttcccctttaactacgtggaaaattacaccgtctccacagaggtg gcctccatggagttccgcactgaaaacggaacgcagattcccatctccggactggacgac agtctcgcaatcaccgttgcgattaacaatgggagcagtgcagcggaggccggtcctgag ggtgctggtactggtggggtccccacagctggagctgtgaacatcagccactgtgactct gtgatagtcaagatcagtgcgggaaacaccaacaggcaggcggggctgtttgtgcagctc aacttcacctctctgcatggtgtcagtgagaaggaaaaagcagaagaggagccatacatc acagcctaccttcactcacatgacagacccaacgaattcaactgcacagacagaaaacag atctccctcagtatgaccagggggcaggatctggaccacaggaaatacaccttcttcctg tcgcctgagtcgtacgacaccactctggactacttcatcaacgtgagcacgacctgcagc cccagctcccacccgctgggcgttcacctggaggtcggtgtgtttgcctctctgtgtcag tacttcagtgagagtgagaagcagtggcggacagacggcatggtgcctcttgcggaaacc aatgccagcagggctgtttgtcgcaccagacacctcacaacctttgctgcaggcctcttc gtcccagccaacgctgtcagctttaaagtgccggaacgctacggtccacccagcctggtc gtcctgttagtgtgcgtgttgggtttactgagttatgtggtggcagcagccatcttgcac aagttggatcagctggatctacggcgggctgctgtggttccactctgtgggggagaagga ctctttaagtatgaggtccaggtgaagaccggctggagccgaggggctggcaccacggct cacgtgggaatcagtttgtacgggcgcgagagccgcagcggacaccgacacctcgacagc agaggagctttcacacgcaatgctctcgacatctttcatatcgccacagataccaacctg ggcagtgtctggaaaatacgaatctggcacgacaacaagggtctgtccccagcgtggatg ctccagtatgttttgatcaaagacttgcagacaggaagcagctactacttcctggttgag gagtggctgtcggtggataatgagaaaactgacggacgggtggagattgagttggaggcc tctgaggaggctttgcttcttgagatgccccgcctcctgcgctgtgagctgcagagggcg ctgtgtgagagtcacatgtggctgtctctgtgggagagacctccccgcagccccttcacc cgcctgcagagagccacctgctgtgctgtgttgctgcagctcttcgtattcgccaactcg ctgtggtacagcatcgttgtggacaagagatacagctctcaggccgtgtcgaggttgtct tcactgaacggcgagacggtggcagcaggtgtggtgacctgtttgatagtgtatcctctc tacctgctcgtcttcacagtctttagaatgagccgcagtaagtgcgtgactgttgagcag gtgcagccacaatcagaccaggagtctgtggagatcgatgacttcctggaaaactccatg aatggaagttccttcctcttcttcaatggcgagaccaactcagaggaaaccaatctggat tttcccactccatcaactaaaagtgtggagagctgggctatggcagaggaggagatggag gacagggattggccagagtggttgagtgacggatccgtggtgggaggggcggggcacggg gcaggaatgcccaggcttaagaggggtcaggggagtaggcaccttggtgtggacatggcc ttcaaccccgacgacgaggaggggaccggagaacgcaacaaatatttcacctcctcagat gaggatctgatcaaacacatcctcacagatggacagaacttcttccctcaggcagatgaa agtgaaatggctgatctgtccagcattttggatgataagactgaagtgatcctcctccag aggccgaatgaatttcttcctccaggagctctgagaagaccaaaaacggctttcacctcg aacacagttgtgacagatgtgtgtcgccccaggcggtttcctccctggtgtggacgtgca gccctctggggcagctgggcggggatcgctctggccagtggtgtttccatttgggccggc cacgggttcagtcagaatgtggccatgatgtggctcatctcctgtttctcaagcttcctg tcctcctgcctggtgctcgagcccattaaggtgttgtgtgaggccgtttactacgctgtg tatgtgcaacgcctgcgtccagaggaccaggatgtgctggtggagttcccccgggtggag agagtggtccaacgggtgcctcgggtgagacccccacagggctttgcgttgtctcaggcc cgacaccaggcccgcaaagtccacatgctgtacaccatgctgaagaatttcctggtttac atgtttttcctgttggtggttttgcttctcaactattctgactcggctaaagacacacac ggcctgagactgcgcactcagctgcagcgagctctacatgcacctgagtaccacaacatc agcagccgaggtgatgttctcctgtggctgaacgggtccttgttgccacggctactggat gacacggccctcttgagagacacaggcagtgtgttactcggcacactgaggctccgtcaa atccgtgacacacaggatgctcttggttcctgggcaggagagagcgatcagggaaaggaa caatctctgagtcaaggagctgagaacgtgtctgcttttggagctaacaatacaaaatgg gggtggcgtttggatgtgtataacagcggagatgtggttcaacagctgaacagaagcctg gcgcaggcctcgtcctccttacagcagctgcagcagctgcactggctcgactacaggact cgcgctctttttgtggagttctcactctacaacgtcaacacaaacctcctggctgtcttc tccttcctgtttgagttccctgtttctgagcgtgctcagtccagccttgacctctttgtc atcagtctttggccaatcacaggcctggacctgcagctccttctcatgactgtcctcatg gcgctggtcttgtacttcttggttcgggggatcttgggcttcctcagagaaggccatgtg tacttgttctcagcctggaggctcctaggcatctgcaaactgactctggcggcctctgtg tgcgggctacacctgagccgctgcaccatggcatcgcagcagtgggcgtcatacctgaag cacccacgggacgccttcacagacttctaccctctggcccgacagagtcagatgtacacc gtcatgtctgcattgctgttgttcatcctcgtgctcaaggcctcccaccagttgcggttc ctcagagagtgggccgtgtttggcagagctctgcgctgctcagtctgggagctgctggga gtcgccctggcgttactgctgttgttgctggctttctcacacacaggacacctgctcttc cactctgtattggacggctacggcagtgtgagctctgccagtcagtccctgttgggtgct ggtggacgtggtcttctgtcatggcgtcccacctggatgactaccggtccctccaacact gtgacctcattgatgttccatgccagctttgccatacttcggctggtgttgctttggttg ctcacatctgtgttgctgaggaactaccggcgtgcaagagcggagctgtaccgtcccgca ggggatctccaagactacgagatggttgagctgttcctgcgacggctcaaaatgtggatg gggctcagcagggccaaggagtttcgtcataaggtacgttttgagggcatggagttacca ccatctcgttcgtcttctaccagcgattgtaagtccctgtgcctgccaccactggaccgt cctgactccccttccaccccagacagtgttgatggaggttctgaggcctcgtggcgccct acttcctctagcccctgcagcctgaccgaagcccctggaatcggcctgggactcgggctg ggcctcggtttggggcttggcccaggagtggtgatgggaagtaccagctggagggagaga gctgagaccgaagcctctctgaggaggctccttcctaccctggacgccctcctgcaacag cttgaccgtgtcactattgccaccgaggatctttaccacgtggagtgtaaaatggagcga tcccagagaaaaaagaggagtagaggacgggagaagggagatagtggtggtcagggaggg agaagtgaggcagggcatagagcaaaaggagaggagaaggacgctactggatggcgagat cgaaaaactggcaaagaaaaacaaaaagggagcaaaaaggggaaaaagacagataaaagt gaacttagaaaagactgtggaaacacctctgctaaccccaaaaagactacagaagccaca catgctccccttataaagcctcaaccttcccctgctactacacaaacccctgctcctcaa tcatcaaccaaacctttagctagtgcacctccgccaacaccagtcaaagataaatctgcc tctggcttttcctctcccgtttcatcagcgaacactcccccttcacgtgtcccactaccc aaaacacccaccgcacctccatgcactcctgcaccaacctcttcttctttttctacccct gcccctacgccagtaggtggggattgggacccacccacggagagagagaccttcccttcc tccagtctgttcaaccacccagctcacacaaccacaatacctacacgcaagcgaaaacgc aaacccccacccctcaaaaacaaggtgcatcccaatctagacaggcagggccctggacac ccaaaaccttga

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