KEGG   Labrus mixtus (cuckoo wrasse): 132993392
Entry
132993392         CDS       T10666                                 
Symbol
plcb2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
lmix  Labrus mixtus (cuckoo wrasse)
Pathway
lmix00562  Inositol phosphate metabolism
lmix01100  Metabolic pathways
lmix04020  Calcium signaling pathway
lmix04070  Phosphatidylinositol signaling system
lmix04081  Hormone signaling
lmix04082  Neuroactive ligand signaling
lmix04261  Adrenergic signaling in cardiomyocytes
lmix04270  Vascular smooth muscle contraction
lmix04310  Wnt signaling pathway
lmix04371  Apelin signaling pathway
lmix04540  Gap junction
lmix04621  NOD-like receptor signaling pathway
lmix04912  GnRH signaling pathway
lmix04916  Melanogenesis
Module
lmix_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:lmix00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    132993392 (plcb2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    132993392 (plcb2)
   04371 Apelin signaling pathway
    132993392 (plcb2)
   04020 Calcium signaling pathway
    132993392 (plcb2)
   04070 Phosphatidylinositol signaling system
    132993392 (plcb2)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    132993392 (plcb2)
   04081 Hormone signaling
    132993392 (plcb2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    132993392 (plcb2)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    132993392 (plcb2)
  09152 Endocrine system
   04912 GnRH signaling pathway
    132993392 (plcb2)
   04916 Melanogenesis
    132993392 (plcb2)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    132993392 (plcb2)
   04270 Vascular smooth muscle contraction
    132993392 (plcb2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:lmix04131]
    132993392 (plcb2)
Enzymes [BR:lmix01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     132993392 (plcb2)
Membrane trafficking [BR:lmix04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    132993392 (plcb2)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    132993392 (plcb2)
SSDB
Motif
Pfam: PI-PLC-X PH_14 PI-PLC-Y PLC-beta_C PLCB1-4-like_EFh EF-hand_like C2
Other DBs
NCBI-GeneID: 132993392
NCBI-ProteinID: XP_060919199
LinkDB
Position
18:11142476..11162088
AA seq 1267 aa
MNKKRHFLEPPEVKDYLVKGDRFTKWSEDSTKTHPVTMKMDPKGFYVYWINQSKETTFLD
VATIRDTRIGKYAKLPKHPKVRNVFNLDFPDSNHLAKTLTIVSGPDTVNLTYHNFFASKE
KVTQNWANEIFAIAYNAARNNACRQVFLEKIYVRISLHTNKDGKIPVKYIYKMFPADKKR
VESALASAHLPKGKYDSMKPDVFTEAAYKTFLTHLCPRPEIYEIFTSYSNKPIMTKENFT
KFLNEKQRDSRLNEELFPRLRQDQIKALIDKYEPLSANSNRNLISPEGLLFFLMGPETSV
VVQDRLAKSQDMTQPIPHYFIKSSHNTYLTAGQFSGVSSPEMYRQCLLSGCRCLELDCWK
GKPPDEEPIITHGFTMTTEILFKDVIEAIAESAFKTSQYPVILSFENHVDSVKQQEKMAD
YCKTIFGDALQTEPLDKYPLKPGQQIPSPSELMGKILIKNKKGSHAKPAQNKKTSTAATD
QTTATAAPTQDPNISSTDPANPAPSAQENQEGDAAVEDNEETEETDEQDEEKMKTSDEGT
AGQEVTAYEAMSSIVNYIQPNKFISFDNARKKNKSYVISSFVETKGETMIAKTAVEFVEY
NKRQMSRIYPKGTRMDSSNYNPQPFWNVGSQMVALNYQTMDFPMQLNMALFEFNGRTGYL
LKHDVLRRSDKKFDPFCDRIDTVVASTLTIKIYSGQFLSDKNVKTGVEVEVIGLPGDPKK
KYRTKWSTTPNAINPVWNEEPFVFDKILLPEMASLRIVVHEENGKFLGHRIIPLDAIQSG
FHHICLRSESNMPLTLPALFVFIEVKDYIPAAFADFTDALFNPTKGTEKTTKTPKESSSD
YVSPYEMPLVAQTAAVVAQESEAPVAEKVESEPALQVDASEQSPKSPTDPPQTPEEAPVE
DPAPDAETLPEAVPSSEEPAAVEPTPEEKAPEDPAPEEPAPEEPAPEEEPAPEPEEAPET
KEEPGTESTTKPDPQDTEAAEEPAAVVLPVPAAVASPESLVSNESPQPPTSSEEPSTVPT
EELTQHKNYLKVVKRQEREMKEAEKKYQKKGEDLIQKYSDSFKAMKKKASLKKKEGEKNS
SDSSLKTERVQEQKDKMYVELQALWTEQCDQLKKRKEQCATERLAKLLEMATERHTTELK
TLESESKENKKKSISKCSSSEKAKLKKTMSTELLDETSQSDASSSDNSPQQEALMKKQAV
TLEEIKTLTNQLNQEALKEQAQRMRSIPAEVREAVNVCVGAHFPELVDQSDGKKVEGVGF
YGDVFLG
NT seq 3804 nt   +upstreamnt  +downstreamnt
atgaacaagaaaagacactttctggagcctccagaggtcaaagactacctggtcaaagga
gatagatttaccaagtggtcagaggactcgacaaagactcatcctgtcaccatgaaaatg
gatcccaaaggtttttatgtctactggatcaaccaaagcaaggagacaacgttcctggat
gttgctaccatcagagacaccagaataggaaaatatgcgaaacttccaaaacaccctaag
gttcgcaacgtgttcaacctcgactttccagacagcaaccaccttgccaaaactctgacc
atcgtctcaggtccagacactgtgaatctgacctatcataacttctttgcctccaaagag
aaagtgacacagaattgggcaaatgaaatctttgcaattgcatacaatgctgccaggaac
aatgcatgcagacaagtcttcctggagaaaatatacgtgcgtatttctcttcacaccaac
aaggacggcaagatcccagtgaaatatatttacaagatgttccctgcggataagaagagg
gtggaaagtgccttagcatcagcacacctccctaaaggaaagtacgactccatgaagccg
gatgtcttcactgaggctgcctataagaccttcttgacacatctctgccctcggcctgag
atctacgagatcttcacttcttactccaacaaacccatcatgacgaaggaaaacttcacc
aagttcctcaacgagaagcagagggactctcgcctcaacgaggagctgttcccacgtctg
cggcaggaccagatcaaggctttgatcgacaaatatgaacccctctctgccaactcgaac
agaaatctgatctctccagagggcctgttgttcttcctcatggggccagagacgtcagtg
gtcgtgcaggacaggctggccaagagtcaggacatgacccaacccatcccccactacttc
atcaagtcctcccataacacatacctgacagctggtcagttctcgggcgtgtcctccccg
gaaatgtaccgtcagtgtctgctgtccggctgccgctgtctggagctggactgctggaag
ggcaaacctccagatgaagagccaatcattacccatggtttcaccatgacaaccgagatc
ctattcaaggatgtaattgaagccattgccgagagcgccttcaagacctcacagtacccg
gttatcctctcattcgagaaccacgttgactcggtgaaacagcaggagaagatggcagac
tactgcaaaaccatatttggtgatgccctgcaaacagagccactggacaaataccctcta
aagccaggccagcagatccccagcccatctgagctcatgggcaagatcctaatcaaaaac
aagaagggcagccatgcaaagccagcccagaataagaaaaccagcacagcagcaactgac
cagaccacagccacagctgcacccactcaggacccaaacatctcctccacagatcctgcc
aacccagcacccagcgcccaggagaaccaagagggggacgcagctgtggaggacaacgag
gagacggaggagacagacgagcaggatgaggaaaaaatgaagacatcggatgagggcaca
gctggacaagaagtgacagcatacgaggccatgtcatctattgtcaactacatccagcca
aacaaattcatctcatttgacaatgccagaaagaaaaacaagagttacgtcatatcatct
tttgtggagaccaaaggggagacaatgattgccaagaccgctgttgaatttgtcgaatac
aataaaaggcagatgagcaggatttaccccaaaggaacaagaatggactcatccaactac
aaccctcagccattttggaacgttggctcccagatggtggcgctaaactaccagaccatg
gatttccccatgcagctgaacatggctctgtttgagttcaatggcagaacaggatacctc
ctcaagcatgatgtgctgcggcgcagtgacaaaaagtttgatcctttttgtgacaggatc
gacacagtggtggcgagcacactgacaataaagatctattcaggtcagtttttgtctgac
aagaatgtgaaaactggagtggaggtagaggtgatcggactgccaggagaccccaagaag
aaatatcgcaccaagtggtccaccacacccaacgccattaaccccgtgtggaacgaggag
ccttttgtttttgacaagattctgctcccagaaatggcctctctaagaattgtagttcac
gaagaaaatggtaaattcttgggacacaggatcatcccacttgatgccatccaatcaggt
ttccatcacatctgcctgcgcagtgagagcaacatgccgctcactctgcctgctctgttt
gtcttcatcgaggtcaaggactatatccctgctgcctttgcagatttcacagatgcttta
ttcaacccgacaaagggcacagaaaagaccacaaagaccccaaaggagtcatcctcggac
tacgtttctccctacgagatgcctcttgtggcccaaaccgctgcagtcgtggctcaggaa
agtgaagccccagttgcagaaaaagtagaatctgaacctgcactacaggttgatgccagt
gagcaatcaccaaagtctccaacggatcctcctcaaactcctgaggaggcccctgttgag
gatccagccccagatgcagaaacccttcctgaagctgttccatcctctgaagagccggct
gctgtagaaccaacccctgaggaaaaagcccctgaagatccagcccctgaagagccggca
cctgaagagccggcacctgaggaggaacccgctccagagccagaggaagctcctgaaact
aaggaggagcctgggactgagtccactacaaagccagatccacaagacacagaagctgct
gaagaacctgctgctgtggtcctgcctgttccagcagcagttgcatcgcctgagtcctta
gtatcaaatgagtcacctcagccgcccacgtctagtgaagagccttcgactgttcccacc
gaagaactgacacagcacaagaactacctgaaggtcgtcaagcgtcaggagagagagatg
aaggaagcagaaaagaagtatcagaaaaaaggagaggacctgattcagaaatattctgac
tccttcaaggccatgaagaagaaggcctcattgaagaaaaaggagggagaaaagaactcc
tctgactccagcctgaagacggagcgggtgcaggagcagaaggacaaaatgtatgtcgag
ctgcaggctttgtggacggagcagtgcgaccagctgaagaagaggaaggagcagtgtgct
acagagagactggccaaactgttagagatggcaacagagagacacaccactgagctgaag
accctggagagcgaatccaaagaaaacaagaagaaatcgatctcaaaatgttcctcctca
gagaaagcaaagctgaaaaagacaatgagcacagagctgctggatgaaacaagtcagtct
gatgcttcttcttcagataacagcccgcagcaagaggctctgatgaagaaacaagctgtt
acactggaggagatcaagaccctgaccaatcagctcaatcaggaagccctgaaggagcaa
gctcagagaatgaggtctattccagccgaggtgagggaggccgttaacgtctgtgtgggg
gcccactttcctgaactggtcgaccagtcagacggcaagaaggtggagggggtcggcttc
tatggggatgtgttcctgggttag

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