Leuconostoc mesenteroides KFRI-MG: LMES_0386
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Entry
LMES_0386 CDS
T02997
Name
(GenBank) UDP-N-acetylmuramyl pentapeptide synthase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
lmk
Leuconostoc mesenteroides KFRI-MG
Pathway
lmk00300
Lysine biosynthesis
lmk00550
Peptidoglycan biosynthesis
lmk01100
Metabolic pathways
lmk01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
lmk00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
LMES_0386
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
LMES_0386
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
LMES_0386
Enzymes [BR:
lmk01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
LMES_0386
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
LpxD
Motif
Other DBs
NCBI-ProteinID:
AHF18602
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Position
407942..409270
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AA seq
442 aa
AA seq
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MNYSVKKIGQILNATTQIDSKIVTGVSFDSRKVKSGDLFVALVAENDGHDYVQQALTKGA
TAVLVDDRHQIDSKIPAIIVSDTLLALQQLGEYRRHQINPKVVAITGSNGKTTTKDMTSA
IMGSQYKTFKTPENFNNEIGVPLTLLTMPDDTEVLVVELGMDRPGQLTTLSELVSPDIAI
ITMIGEAHIEFFRTRENIAKAKLEITKGLKSQGTLLIPYDEPLLTNAQVKQNVQTFGQDI
KDINSSSSKTIFTYQNTRFAIPLLGRYNIMNALAAISAGILLHIELKNAAEALQHFDLTK
NRTEQLTTSHGVNLISDVYNSNPTAVAAVLATLKIIPATHKYVVLGDMLELGEQAASLHA
CLAETVINANVDGVYLVGPLMNKYLYPILQRRFDSAHLHQYETDQLAELIKDLQTLGENG
DVILLKASHGIHLENVVNALVK
NT seq
1329 nt
NT seq
+upstream
nt +downstream
nt
atgaattactcagtaaaaaagataggtcagatattaaatgcgacaacacaaatagattcc
aaaatagttactggtgtgtcttttgattctcgtaaagttaaatctggagatttatttgtt
gctctggttgctgaaaacgatgggcatgattatgtgcaacaggcgttgacaaaaggggcc
acagccgttttagtggacgacaggcatcaaatagattcaaaaattccagctattattgta
tcagacacattgttagctcttcagcaattgggagaatatcgtcgtcatcaaattaatcct
aaagttgttgctattactggttcaaatggtaaaacaacaacaaaagatatgacttcggca
ataatgggttctcaatacaaaacctttaaaacacctgaaaactttaacaatgaaattggt
gttcctttgacgttgctcactatgccagatgatacagaagtgttagtggtagaattaggt
atggatcgacctggtcaattgacgacattatctgagttagtgagtccagacattgccatc
attactatgattggagaggcgcatattgagtttttcagaacacgtgaaaatatcgctaag
gcaaaactcgaaattactaaaggtctcaaatcacaaggaacattattgattccttacgat
gaacctctcctgacaaatgcacaagttaaacaaaatgtgcaaacctttggacaagatatt
aaagatattaattcgtcatcctccaagacaatttttacttatcaaaatactcgatttgct
attccactgttgggtcggtataatataatgaatgcgctcgcagcgatttcagcgggtatc
ttattacatattgaattaaaaaacgctgcagaagcgcttcagcattttgatttgacaaaa
aatcgcacagaacagctcaccacatctcacggcgtgaacttaattagcgatgtttataac
tcaaatccaacggctgttgctgctgtcttggcaacattaaaaattataccggccacacac
aagtatgttgtgttgggtgatatgttagaattaggcgaacaggctgcaagcttgcacgct
tgtctggcagaaacggtgataaatgcgaatgttgatggcgtttacttggttggaccattg
atgaataaatatctatatccaatcttgcaacgacgctttgattcagcgcacttgcaccaa
tatgaaacagatcagttagccgaattaatcaaagatttacagacgttaggtgaaaacggg
gacgtgattttgttaaaagcaagtcatgggattcatcttgagaacgttgttaacgcattg
gtaaaatag
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