| Entry |
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| Symbol |
cobA
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| Name |
(GenBank) uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase
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| KO |
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| Organism |
lml Listeria monocytogenes L99 (serotype 4a)
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| Pathway |
| lml01110 | Biosynthesis of secondary metabolites |
| lml01120 | Microbial metabolism in diverse environments |
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| Module |
| lml_M00924 | Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide |
| lml_M00926 | Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme |
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| Brite |
KEGG Orthology (KO) [BR:lml00001]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
lmo4a_1183 (cobA)
Enzymes [BR:lml01000]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
lmo4a_1183 (cobA)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
lmo4a_1183 (cobA)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
1184226..1185707
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| AA seq |
493 aa
MGKVMLIGAGPGDAQLLTVKGLAALRKADVIVYDRLVEPAMLQERKASCKLIYVGKEPLH
HPIPQEEIEQILVREAATNELVVRLKAGDPYVFGRGGEEGETLYKAGIPFEVIPGITSAI
GGLAYAGIPVTHRDFASSFHVITGHLKKGRDPLDWEALARLEGTLVFLMGMTNLPNICAN
LLENGRKAETGVAIVQWASRGKQLTVTGNLQNIEQKVAESGISSPALIVVGDVVSLRPQL
NFFEEMPLFHTKVLLPRARAGKSMLAEQIRDLGGEVTMYPNIQVVDVAPTKTREALIEIN
ELLFTSKEAVERFFDYLTKLDLDIRSLKNTHLTAIGKQTKEAFSEKGIIPDSFIKRRSTE
LILEHLPRLQKNASNLIIGSIVDTSEVNAILAEVEAMEMMPLYDMRPVTERPFDLASFEQ
VCFSSSRSVQNLLDVLTTEEKAILQTKTILSIGRFTSATLASFGINNFIEAESATPESLI
ELIQKTKLEGVPQ |
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| NT seq |
1482 nt +upstreamnt +downstreamnt
atgggaaaagtcatgttaattggtgcaggtcctggagatgcacagttgctaaccgtgaaa
ggcttagctgcactgcgaaaggcagatgttattgtatacgatcgcctcgttgaaccagcg
atgctccaagaacgaaaagctagttgtaaactcatttatgtcggaaaagaaccacttcat
catccaattccccaagaggaaatcgaacaaattcttgttagagaggctgcgacaaatgag
ctggttgttcgtctaaaagcaggagacccttatgtgtttggtcgcggcggggaagaagga
gagacactctataaagcgggaattccatttgaagttattcctggaatcacatccgcgatt
ggtgggcttgcctacgctggaattccagtaacccatcgtgattttgcttcgagttttcac
gtgattactggacatttgaaaaaaggacgtgatccactagattgggaagcccttgctaga
ctggaaggtacgctcgttttcctaatgggaatgactaatttacctaatatttgtgcgaac
ctactagaaaatggtcgaaaagccgaaacgggtgttgcgattgtacaatgggcatctcgc
ggcaaacaattaacggttaccgggaacttacaaaacatcgaacaaaaagtagcggagtct
ggtatttcttcgccggcacttattgtcgttggtgatgtggtgagcttacgaccacagctt
aacttctttgaggaaatgcctcttttccatacaaaagtattacttccaagagcacgagct
ggaaaaagtatgctcgcggaacaaattcgcgatttgggcggagaagtaactatgtatcca
aatattcaagtagtcgatgttgcgccaacgaaaacaagggaagcgctaatcgaaataaac
gaacttcttttcacatctaaagaagcggtagaacgatttttcgactatttaaccaagctt
gatttagatattcgttctctaaaaaatacccatcttactgctattggcaaacaaacaaaa
gaagcttttagtgaaaaaggaattattccagatagttttattaaaagacggagcacggaa
ttaattttggagcatttaccacggttacagaaaaatgcgagcaacttaattatcggaagc
atagttgatacgtcggaagttaacgcaattttagcagaagtggaagcgatggaaatgatg
ccgttatatgatatgcgtcctgtgacagaacgaccatttgaccttgcaagctttgaacaa
gtttgtttctcaagttcgcgttccgttcaaaatttactcgacgtactaacaaccgaagaa
aaagccattttacaaacgaaaacaattctttccattggaaggttcacgagcgcaacgtta
gcatcattcggtatcaacaactttatcgaagccgaaagcgccacaccagagagcttaatt
gaactaatccaaaaaacaaaattagaaggagtaccacaatga |
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