Listeria monocytogenes 08-5578 (serotype 1/2a): LM5578_2189
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Entry
LM5578_2189 CDS
T01157
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
lmn
Listeria monocytogenes 08-5578 (serotype 1/2a)
Pathway
lmn00290
Valine, leucine and isoleucine biosynthesis
lmn00620
Pyruvate metabolism
lmn01100
Metabolic pathways
lmn01110
Biosynthesis of secondary metabolites
lmn01210
2-Oxocarboxylic acid metabolism
lmn01230
Biosynthesis of amino acids
Module
lmn_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
lmn00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
LM5578_2189 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
LM5578_2189 (leuA)
Enzymes [BR:
lmn01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
LM5578_2189 (leuA)
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
Herpes_gp350_A
Motif
Other DBs
NCBI-ProteinID:
ADB68936
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All DBs
Position
2178130..2179668
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AA seq
512 aa
AA seq
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MKKIQFFDTTLRDGEQTPGVNFDVKEKIQIALQLEKLGIDVIEAGFPISSPGDFECVKAI
AKAIKHCSVTGLARCVEGDIDRAEEALKDAVSPQIHIFLATSDVHMEYKLKMSRAEVLAS
IKHHISYARQKFEVVQFSPEDATRSDRAFLIEAVQTAIDAGATVINIPDTVGYTNPTEFG
QLFQDLRREIKQFDDITFASHCHDDLGMATANALAAIENGARRVEGTINGIGERAGNTAL
EEVAVALHIRKDFYQAETNIVLNQFKNSSDLISRLSGMPVPRNKAVIGGNAYAHESGIHQ
DGVLKNPDTYEIITPALVGVDKNSLPLGKLSGKHAFNTRMEEMGYTLTEQEQKDAFKRFK
QLADAKKEVTEEDLHALILGQSSESADDFELKHLQVQYVTGGVQGAIVRIEERDGALVED
AATGSGSIEAIYNTINRLMKQDIELTDYRIQAITAGQDAQAEVHVVIKNDKGAEFHGIGI
DFDVLTASAKAYLQASGKSKTASKQADFEEVK
NT seq
1539 nt
NT seq
+upstream
nt +downstream
nt
atgaagaaaatccagttttttgatactacacttagagatggcgaacaaacccctggagtt
aattttgacgtaaaggagaaaatccagattgccttacaactcgaaaaacttggaattgat
gtgattgaagccggctttccgatttcttctcctggagattttgaatgcgtcaaggccatt
gcaaaagcgattaaacattgttctgtaacagggctagcgcgctgtgttgaaggagatatc
gaccgcgcggaagaagcgcttaaagacgctgtttctccgcaaatacatatcttcttagca
acgagcgatgtgcatatggaatacaaattaaaaatgagtcgggcggaagttcttgcttcc
attaaacaccacattagttatgcaagacaaaaattcgaagtagtacagttttcaccagaa
gatgcaactcggtcagatcgtgcttttctaattgaggccgttcaaacagcaattgatgcc
ggggcaactgtcatcaacattccggacacggtcggatatactaacccaaccgaattcgga
cagctattccaagatttgcgtagggaaattaaacaatttgatgatattactttcgcttcc
cattgtcatgatgaccttggtatggcgactgcaaatgcacttgctgcaatcgaaaatggc
gcaagacgcgtcgaaggtacaattaatgggattggcgaacgagctgggaatacggctctt
gaagaagttgctgtcgcgctgcatattcgcaaagatttttatcaagcagaaacaaatatc
gttttgaaccaatttaaaaattctagtgatctgattagtcgtttgtcgggtatgcctgtt
ccgcgtaataaagccgtaattggtggtaatgcttacgcgcacgagtccggtattcatcaa
gatggcgtgctgaaaaacccagatacgtatgaaatcatcacccctgcccttgtcggcgtg
gataaaaactcgcttcctcttggtaaactttctggcaaacatgccttcaatacgcgcatg
gaagaaatgggctacacactaaccgaacaagaacaaaaagatgcctttaaacgtttcaaa
caactagcagatgcgaaaaaagaagtaactgaagaagacttgcacgcgttaattctcggc
caatcttccgagtcagccgatgatttcgaactaaaacatttgcaagttcaatatgttact
ggcggcgtccaaggtgcgattgttcgcattgaagaacgtgatggcgctctagtagaagat
gcagcaactggttcaggtagcattgaagcgatttacaacacaattaatcgcctaatgaaa
caagacatcgaattaaccgattatcgtatccaagcaattacagccggccaagatgcccaa
gcagaagtccatgtcgtcattaaaaatgacaaaggcgctgagttccatggtatcggtatt
gattttgacgttttaaccgctagtgctaaagcttatttgcaagcatcaggcaaaagcaaa
accgccagtaagcaagctgatttcgaggaggtaaaataa
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