Listeria monocytogenes L312 (serotype 4b): LMOL312_1990
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Entry
LMOL312_1990 CDS
T02247
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
lmol
Listeria monocytogenes L312 (serotype 4b)
Pathway
lmol00290
Valine, leucine and isoleucine biosynthesis
lmol00620
Pyruvate metabolism
lmol01100
Metabolic pathways
lmol01110
Biosynthesis of secondary metabolites
lmol01210
2-Oxocarboxylic acid metabolism
lmol01230
Biosynthesis of amino acids
Module
lmol_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
lmol00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
LMOL312_1990 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
LMOL312_1990 (leuA)
Enzymes [BR:
lmol01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
LMOL312_1990 (leuA)
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
Ribosomal_S5
Motif
Other DBs
NCBI-ProteinID:
CBY68068
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Position
2048491..2050029
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AA seq
512 aa
AA seq
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MKKIQFFDTTLRDGEQTPGVNFDVKEKIQIALQLEKLGIDVIEAGFPISSPGDFECVKAI
AKAIKHCSVTGLARCVEGDIDRAEEALKDAVSPQIHIFLATSDVHMEYKLKMSRAEVLAS
IKHHISYARQKFDVVQFSPEDATRSDRAFLIEAVQTAIDAGATVINIPDTVGYTNPTEFG
QLFQDLRREIKQFDDIIFASHCHDDLGMATANALAAIENGARRVEGTINGIGERAGNTAL
EEVAVALHIRKDFYQAETNIVLNQFKNSSDLISRLSGMPVPRNKAVIGGNAYAHESGIHQ
DGVLKNPDTYEIITPALVGVDKNSLPLGKLSGKHAFNTRMEEMGYTLTEQEQKDAFKRFK
QLADAKKEVTEEDLHALILGQSSESADDFELKHLQVQYVTGGVQGAIVRIEERDGALVED
AATGSGSIEAIYNTINRLMKQDIELTDYRIQAITAGQDAQAEVHVVIKNDKGAVFHGIGI
DFDVLTASAKAYLQASGKSKTASKQADFEEVK
NT seq
1539 nt
NT seq
+upstream
nt +downstream
nt
atgaagaaaatccagttttttgatactacacttagagatggcgaacaaacccctggagtt
aattttgacgtaaaggagaaaatccagattgccttacaactcgaaaaacttggaatagat
gtgattgaagccggctttccgatttcttctcctggagattttgaatgcgttaaggcgatt
gcaaaagcgattaaacattgttctgtaacagggctagcgcgctgtgttgaaggagatatt
gaccgtgccgaggaagcgctaaaagacgctgtttctccgcaaatacatatcttccttgca
acgagcgatgtgcatatggaatacaaattaaaaatgagtcgggcggaagttcttgcttcc
attaaacaccacattagttatgcgagacaaaaatttgatgttgtacagttttcaccagaa
gatgcaactcggtcagatcgtgcttttctgattgaagcagttcaaacagcgattgatgca
ggagcaactgtcatcaacattccagatacggtcggatatacaaaccccaccgaatttggg
caattattccaagatttgcgccgcgaaataaagcaatttgatgatattattttcgcttct
cattgccatgatgaccttggtatggcgacagcaaacgcacttgctgcaatcgaaaatggc
gcaagacgcgtcgaaggtacgattaatgggattggtgagcgtgctgggaatacggcactg
gaagaagttgcggtagcgcttcatattcgcaaagatttttatcaagctgaaacaaacatt
gtattgaatcaatttaaaaattcaagtgatttgattagccgcttgtctggtatgcctgtt
ccacgtaacaaagctgtaattggtggcaatgcttacgcgcatgaatctggtattcatcaa
gatggtgtcctaaaaaatcctgatacgtatgaaatcatcacccctgcccttgtcggcgtg
gataaaaactctcttccacttggcaaactttctggcaaacatgccttcaatacgcgcatg
gaagaaatgggctacacactaaccgaacaagaacaaaaagatgcctttaaacgtttcaaa
caactagcagatgcgaaaaaagaagtaacagaagaagacttgcacgcgttaattctcgga
caatcttccgagtcagccgatgatttcgaactaaaacatttgcaagttcaatatgttact
ggcggcgtccaaggtgcgattgttcgcattgaagaacgtgatggcgctctagtagaagac
gcagcaactggttcaggtagcattgaagcgatttataatacgattaaccgtcttatgaaa
caagatattgaattaaccgattatcgtatccaagcaattacagccggtcaagatgcccaa
gcagaagtccatgtcgtcattaaaaatgacaaaggcgctgtgttccatggtatcggtatt
gattttgacgttttaactgctagtgctaaagcttatttgcaagcatcaggcaaaagcaaa
accgccagtaagcaagctgatttcgaggaggtaaaataa
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