Listeria monocytogenes SLCC2378 (serotype 4e): LMOSLCC2378_1206
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Entry
LMOSLCC2378_1206 CDS
T02240
Symbol
cobA
Name
(GenBank) uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
lmoo
Listeria monocytogenes SLCC2378 (serotype 4e)
Pathway
lmoo00860
Porphyrin metabolism
lmoo01100
Metabolic pathways
lmoo01110
Biosynthesis of secondary metabolites
lmoo01120
Microbial metabolism in diverse environments
lmoo01240
Biosynthesis of cofactors
Module
lmoo_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
lmoo00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
LMOSLCC2378_1206 (cobA)
Enzymes [BR:
lmoo01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
LMOSLCC2378_1206 (cobA)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
LMOSLCC2378_1206 (cobA)
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GFIT
Motif
Pfam:
TP_methylase
HEM4
Motif
Other DBs
NCBI-ProteinID:
CBY72973
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Position
1202982..1204463
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AA seq
493 aa
AA seq
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MGKVMLIGAGPGDAQLLTVKGLAALQKADVIVYDRLVEPAMLQERKASCKLIYVGKEPLH
HPIPQEEIEQILVKEAATNELVVRLKAGDPYVFGRGGEEGETLYKAGIPFEVIPGITSAI
GGLAYAGIPVTHRDFASSFHVITGHLKKGRDPLDWEALARLEGTLVFLMGMTNLPNICAN
LLENGRKAETGVAIVQWASRGKQLTVTGNLQNIEQKVAESGISSPALIVVGDVVSLRPQL
NFFEEMPLFHTKVLLPRARAGKSMLAEQIRDLGGEVTMYPNIQVVDVVPTKTKEELSEVS
ELLFTSKEAVERFFDYLAQLDLDIRSLKNTHLTAIGKQTKEAFSEKGIIPDSFIKRRSTE
LILEHLPRLQKNVSNLIIGSIVDTAEVNAILAEVEAMEMMPLYDMRPVTERPFDLASFEQ
VCFSSSRSVQNLLDVLTTEEKAILQTKTILSIGRFTSATLASFGINNFIEAESATPESLI
ELIQKTKLEGVPQ
NT seq
1482 nt
NT seq
+upstream
nt +downstream
nt
atgggaaaagtcatgttaattggtgcaggtcctggagatgcacagttgctaaccgtgaaa
ggcttagctgcactgcaaaaggcagatgttattgtatacgatcgcctcgttgaaccagcg
atgctccaagaacgaaaagctagttgtaaactcatttatgtcggaaaagaaccacttcat
catccaattccccaagaggaaatcgagcaaattcttgttaaagaagctgcgacaaatgag
ctggttgttcgtctaaaagcaggagacccttatgtgtttggtcgcggcggggaagaagga
gagacactctataaagcgggaattccatttgaagttattcctggaatcacatccgcaatt
ggtgggcttgcctacgctggaatcccagtaacacatcgtgattttgcttcgagttttcac
gtgattaccggacatttgaaaaaaggacgcgatccactagattgggaagcccttgctaga
ctggaaggtacgctcgttttcctgatgggaatgactaatttgcctaatatttgtgcgaac
ttactagaaaatggtcgaaaagccgaaacgggtgttgcgattgtacaatgggcatctcgc
ggcaaacaattaacggttaccgggaacttacaaaacatcgaacaaaaagtagcggaatct
ggtatttcttcgccggcacttattgttgttggtgatgtggtgagcttacgaccgcagctt
aacttctttgaggaaatgccacttttccatacaaaagtattacttccaagagcacgagct
ggaaaaagtatgctcgcggaacaaattcgcgatttaggcggagaagtaacaatgtatccc
aatattcaagtagtagatgttgtgccaacgaaaacaaaagaagaactaagcgaagtaagc
gaacttcttttcacatccaaagaagcggtagaacgattttttgattatttagcccagctt
gatttagatattcgttctctaaaaaatacccatcttaccgctattggcaaacaaacaaaa
gaagcttttagtgaaaaaggaattattccagatagtttcattaaaaggcggagcacggaa
ttaattttggagcatttaccacggttacagaaaaatgtgagcaacttaattatcggaagc
atagttgatacggcagaagttaacgcaattttagcagaagtggaagcgatggaaatgatg
ccgttatatgatatgcgtcctgtgacagaacgaccatttgaccttgcaagctttgaacaa
gtttgtttctcaagttcgcgttccgttcaaaatttactcgacgtactaacaaccgaagaa
aaagccattttacaaacgaaaacaattctttccattggaaggttcacgagcgcaacgtta
gcatcattcggtatcaacaattttatcgaagccgaaagcgccacaccagagagcttaatt
gaactaatccaaaaaacaaaattagaaggagtaccacaatga
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